{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,14]],"date-time":"2026-11-14T10:13:54Z","timestamp":1794651234057,"version":"4.9.1"},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cases Journal"],"published-print":{"date-parts":[[2009,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>Intestinal necrosis and perforation is a clinical and pathological presentation of the infrequently seen mesenteric venous thrombosis in women using oral contraceptives.<\/jats:p>\n          <jats:p>We report a case of a previously healthy 31-year-old female patient, who presented with a 3-day history of abdominal pain.<\/jats:p>\n          <jats:p>Although chest and abdomen radiographs showed small bowel obstruction, conservative treatment failed and the patient developed peritonism. Contrast-enhanced Tomography of the abdomen revealed free air associated with dilated and thickened small bowel. A laparotomy was performed and segmental resection of both small and large bowel was required. The pathological examination showed intestinal ischemia and mesenteric venous thrombosis. There were no further predisposing factors and mesenteric venous thrombosis was ascribed to oral contraceptives.<\/jats:p>","DOI":"10.1186\/1757-1626-2-7416","type":"journal-article","created":{"date-parts":[[2009,7,22]],"date-time":"2009-07-22T12:32:43Z","timestamp":1248265963000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Massive intestinal ischemia, a rare complication of oral contraceptive-induced mesenteric venous thrombosis: a case report and review of literature"],"prefix":"10.1186","volume":"2","author":[{"given":"Eleni I","family":"Efremidou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Kouklakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Tsirogianni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolaos","family":"Courcoutsakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos J","family":"Manolas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolaos","family":"Liratzopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2009,5,18]]},"reference":[{"key":"751_CR1","first-page":"350","volume":"145","author":"JD Schneiderman","year":"1986","unstructured":"Schneiderman JD, Cello PJ: Intestinal ischemia and infraction associated with oral contraceptives. West J Med. 1986, 145: 350-355.","journal-title":"West J Med"},{"key":"751_CR2","first-page":"513","volume":"116","author":"KS Koh","year":"1977","unstructured":"Koh KS, Danzinger RG: Massive intestinal infraction in young women: complication of use of oral contraceptives?. Can Med Assoc J. 1977, 116: 513-515.","journal-title":"Can Med Assoc J"},{"key":"751_CR3","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1097\/00004836-199907000-00023","volume":"29","author":"HA Hassan","year":"1999","unstructured":"Hassan HA: Oral contraceptive-included mesenteric venous thrombosis with resultant intestinal ischemia. J Cl Gastroenterology. 1999, 29: 90-95. 10.1097\/00004836-199907000-00023.","journal-title":"J Cl Gastroenterology"},{"key":"751_CR4","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1023\/B:THRO.0000003323.80742.4d","volume":"15","author":"D Voora","year":"2003","unstructured":"Voora D, Vijayan A: Mesenteric vein thrombosis associated with intravaginal contraceptives: a case report and a review of the literature. J Thromb Thrombolysis. 2003, 15: 105-108. 10.1023\/B:THRO.0000003323.80742.4d.","journal-title":"J Thromb Thrombolysis"},{"key":"751_CR5","first-page":"76","volume":"39","author":"JD Greig","year":"1989","unstructured":"Greig JD: Oral contraceptives and intestinal ischemia. Journal of the Royal College of General Practitioners. 1989, 39: 76.","journal-title":"Journal of the Royal College of General Practitioners"},{"key":"751_CR6","first-page":"634","volume":"66","author":"C Engelke","year":"1995","unstructured":"Engelke C, Bittscheidt H, Poley F: Mesenteric vein thrombosis with hemorrhagic infract of the small intestinal as a complication of oral contraceptives. Chirurg. 1995, 66: 634-637.","journal-title":"Chirurg"},{"key":"751_CR7","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1007\/s10024-004-7079-x","volume":"8","author":"AK Bailey","year":"2005","unstructured":"Bailey AK, Bass J, Nizalik E, Jimenez C: Unusual case of mesenteric venous thrombosis associated with oral contraceptive use in an adolescent girl. Pediatric and Developmental Pathology. 2005, 8: 128-131. 10.1007\/s10024-004-7079-x.","journal-title":"Pediatric and Developmental Pathology"},{"key":"751_CR8","first-page":"167","volume":"53","author":"B Oliviero","year":"2007","unstructured":"Oliviero B, Di Micco P, Guarino G, De Sio I, D'Uva M, Gentile S: A case of thrombosis of the superior mesenteric vein occurring in a young woman taking oral contraceptives: Full and fast resolution with low molecular weight heparin. Clinical Laboratory. 2007, 53: 167-171.","journal-title":"Clinical Laboratory"},{"key":"751_CR9","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1111\/j.1445-2197.1976.tb03216.x","volume":"46","author":"PY Milne","year":"1976","unstructured":"Milne PY, Thomas RJ: Mesenteric Venous thrombosis associated with oral contraceptives: a case report. Aust N J Surg. 1976, 46: 134-136. 10.1111\/j.1445-2197.1976.tb03216.x.","journal-title":"Aust N J Surg"}],"container-title":["Cases Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1757-1626-2-7416.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,2]],"date-time":"2021-09-02T20:07:44Z","timestamp":1630613264000},"score":1,"resource":{"primary":{"URL":"https:\/\/casesjournal.biomedcentral.com\/articles\/10.1186\/1757-1626-2-7416"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5,18]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["751"],"URL":"https:\/\/doi.org\/10.1186\/1757-1626-2-7416","relation":{},"ISSN":["1757-1626"],"issn-type":[{"value":"1757-1626","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,5,18]]},"assertion":[{"value":"19 December 2008","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 March 2009","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 May 2009","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"7416"}}