{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T09:14:40Z","timestamp":1769937280214,"version":"3.49.0"},"reference-count":7,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cases Journal"],"published-print":{"date-parts":[[2009,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>A 23-year-old female patient presented to the outpatient clinic with bilateral nasal obstruction and discharge since birth. Endoscopic examination and paranasal sinus tomography revealed bilateral choanal atresia. She did not have any other congenital abnormalities. Her parents reported cyanosis in childhood that worsened during feeding and improved during crying; however, they had not visited a physician. She did not have remarkable complaints during early childhood or adolescence.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>The patient was operated under general anesthesia, using a 0\u00b0 4 mm rigid endoscope. The orifice was widened with a curette and, to prevent stenosis, mitomycin-C (1 mg\/ml) was applied topically to the nasopharyngeal orifice for 5 minutes. No stents were placed.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Follow-up evaluation at postoperative 12th month showed that her symptoms improved significantly and, on endoscopic examination, both choanae remained patent.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1757-1626-2-9307","type":"journal-article","created":{"date-parts":[[2009,12,17]],"date-time":"2009-12-17T10:55:01Z","timestamp":1261047301000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Bilateral choanal atresia in an adult - management with mitomycin C and without stents: a case report"],"prefix":"10.1186","volume":"2","author":[{"given":"Fadlullah","family":"Aksoy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hasan","family":"Demirhan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yavuz Selim","family":"Yildirim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Orhan","family":"Ozturan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2009,12,11]]},"reference":[{"key":"1381_CR1","doi-asserted-by":"publisher","first-page":"1095","DOI":"10.1177\/000348946107000414","volume":"70","author":"CG Flake","year":"1961","unstructured":"Flake CG, Ferguson CF: Congenital choanal atresia in infants and children. Ann Otol Rhino Laryngol. 1961, 70: 1095-1110.","journal-title":"Ann Otol Rhino Laryngol"},{"key":"1381_CR2","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/S0165-5876(96)01486-3","volume":"40","author":"E Deutsch","year":"1997","unstructured":"Deutsch E, Kaufman M, Eilon A: Transnasal endoscopic management of choanal atresia. Int J Pediatr Otorhinolaryngol. 1997, 40: 19-26. 10.1016\/S0165-5876(96)01486-3.","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"1381_CR3","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1258\/002221504322928099","volume":"118","author":"NK Panda","year":"2004","unstructured":"Panda NK, Simhadri S, Ghosh S: Bilateral choanal atresia in an adult: is it compatible with life?. J Laryngol Otol. 2004, 118: 244-5.","journal-title":"J Laryngol Otol"},{"key":"1381_CR4","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1097\/00005537-199601000-00019","volume":"106","author":"OE Brown","year":"1996","unstructured":"Brown OE, Pownell P, Manning Sc: Choanal atresia: A new anatomic classification and clinical management applications. Laryngoscope. 1996, 106: 97-101. 10.1097\/00005537-199601000-00019.","journal-title":"Laryngoscope"},{"issue":"12","key":"1381_CR5","doi-asserted-by":"publisher","first-page":"1136","DOI":"10.1007\/s00405-006-0108-9","volume":"263","author":"H El-Sawy","year":"2006","unstructured":"El-Sawy H, Siddiq MA, Anbarasu A: Bilateral choanal atresia and paranasal sinus hypoplasia in an adult patient with hypogammaglobulinaemia. Eur Arch Otorhinolaryngol. 2006, 263 (12): 1136-8. 10.1007\/s00405-006-0108-9.","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"6","key":"1381_CR6","doi-asserted-by":"publisher","first-page":"716","DOI":"10.2500\/ajr.2007.21.3100","volume":"21","author":"H Yasar","year":"2007","unstructured":"Yasar H, Ozkul MH: Bilateral congenital choanal atresia in a 51-year-old woman. Am J Rhinol. 2007, 21 (6): 716-8. 10.2500\/ajr.2007.21.3100.","journal-title":"Am J Rhinol"},{"key":"1381_CR7","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1001\/archotol.128.4.398","volume":"128","author":"M Prasad","year":"2002","unstructured":"Prasad M, Ward RF, April MM, Bent JP, Froehlich P: Topical mitomycin as an adjunct to choanal atresia repair. Arch Otolaryngol Head Neck Surg. 2002, 128: 398-400.","journal-title":"Arch Otolaryngol Head Neck Surg"}],"container-title":["Cases Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1757-1626-2-9307.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,2]],"date-time":"2021-09-02T13:53:18Z","timestamp":1630590798000},"score":1,"resource":{"primary":{"URL":"https:\/\/casesjournal.biomedcentral.com\/articles\/10.1186\/1757-1626-2-9307"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12]]},"references-count":7,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["1381"],"URL":"https:\/\/doi.org\/10.1186\/1757-1626-2-9307","relation":{},"ISSN":["1757-1626"],"issn-type":[{"value":"1757-1626","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,12]]},"assertion":[{"value":"3 November 2009","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 December 2009","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 December 2009","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"9307"}}