{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T15:21:54Z","timestamp":1760368914241},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2010,8,19]],"date-time":"2010-08-19T00:00:00Z","timestamp":1282176000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diabetol Metab Syndr"],"published-print":{"date-parts":[[2010,12]]},"DOI":"10.1186\/1758-5996-2-56","type":"journal-article","created":{"date-parts":[[2010,9,8]],"date-time":"2010-09-08T14:14:16Z","timestamp":1283955256000},"source":"Crossref","is-referenced-by-count":4,"title":["Symptomatic cerebral oedema during treatment of diabetic ketoacidosis: effect of adjuvant octreotide infusion"],"prefix":"10.1186","volume":"2","author":[{"given":"Ora","family":"Seewi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Vierzig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernhard","family":"Roth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eckhard","family":"Sch\u00f6nau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,8,19]]},"reference":[{"key":"85_CR1","first-page":"379","volume":"3","author":"N Glaser","year":"2006","unstructured":"Glaser N: New perspectives on the pathogenesis of cerebral edema complicating diabetic ketoacidosis in children. Pediatr Endocrinol Rev. 2006, 3: 379-386.","journal-title":"Pediatr Endocrinol Rev"},{"key":"85_CR2","doi-asserted-by":"publisher","first-page":"2549","DOI":"10.1093\/brain\/awf257","volume":"125","author":"HJ Schoch","year":"2002","unstructured":"Schoch HJ, Fischer S, Marti HH: Hypoxia-induced vascular endothelial growth factor expression causes vascular leakage in the brain. Brain. 2002, 125: 2549-2557. 10.1093\/brain\/awf257.","journal-title":"Brain"},{"key":"85_CR3","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1055\/s-2007-978716","volume":"31","author":"A Bereket","year":"1999","unstructured":"Bereket A, Lang HC, Wilson TA: Alterations in the growth hormone-insulin-like growth factor axis in insulin dependent diabetes mellitus. Horm Metab Res. 1999, 31: 172-181. 10.1055\/s-2007-978716.","journal-title":"Horm Metab Res"},{"key":"85_CR4","doi-asserted-by":"publisher","first-page":"1209","DOI":"10.2337\/diab.44.10.1209","volume":"44","author":"MA Hussain","year":"1995","unstructured":"Hussain MA, Studer K, Messmer EP, Froesch ER: Treatment with insulin-like growth factor I alters capillary permeability in skin and retina. Diabetes. 1995, 44: 1209-1212. 10.2337\/diabetes.44.10.1209.","journal-title":"Diabetes"},{"key":"85_CR5","doi-asserted-by":"publisher","first-page":"2968","DOI":"10.1210\/jc.81.8.2968","volume":"81","author":"PD Lee","year":"1996","unstructured":"Lee PD, Pivarnik JM, Bukar JG, Muurahainen N, Berry PS, Skolnik PR, Nerad JL, Kudsk KA, Jackson L, Ellis KJ, Gesundheit N: A randomized, placebo-controlled trial of combined insulin-like growth factor I and low dose growth hormone therapy for wasting associated with human immunodeficiency virus infection. J Clin Endocrinol Metab. 1996, 81: 2968-2975. 10.1210\/jc.81.8.2968.","journal-title":"J Clin Endocrinol Metab"},{"key":"85_CR6","doi-asserted-by":"publisher","first-page":"585","DOI":"10.2337\/diacare.22.4.585","volume":"22","author":"KM Thrailkill","year":"1999","unstructured":"Thrailkill KM, Quattrin T, Baker L, Kuntze JE, Compton PG, Martha PM, rhIGF-I in IDDM Study Group: Cotherapy with recombinant human insulin-like growth factor I and insulin improves glycemic control in type 1 diabetes. Diabetes Care. 1999, 22: 585-592. 10.2337\/diacare.22.4.585.","journal-title":"Diabetes Care"},{"key":"85_CR7","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1172\/JCI0213776","volume":"109","author":"V Poulaki","year":"2002","unstructured":"Poulaki V, Quin W, Joussen AM: Acute intensive insulin therapy exacerbates diabetic blood-retinal barrier breakdown via hypoxia-inducible factor alpha and VEGF. J Clin Invest. 2002, 109: 805-815.","journal-title":"J Clin Invest"},{"key":"85_CR8","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1186\/1471-2407-10-184","volume":"10","author":"C Zhang","year":"2010","unstructured":"Zhang C, Hao L, Wang L, Xiao Y, Ge H, Zhu Z, Luo Y, Zhang Y, Zhang Y: Elevated IGFIR expression regulating VEGF and VEGF-C predicts lymph node metastasis in human colorectal cancer. BMC Cancer. 2010, 10: 184-10.1186\/1471-2407-10-184.","journal-title":"BMC Cancer"},{"key":"85_CR9","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1080\/13813450902949012","volume":"115","author":"Z Laron","year":"2009","unstructured":"Laron Z: Insulin and the brain. Arch Physiol Biochem. 2009, 115: 112-116.","journal-title":"Arch Physiol Biochem"},{"key":"85_CR10","doi-asserted-by":"publisher","first-page":"1459","DOI":"10.1210\/jc.75.6.1459","volume":"75","author":"S Ezzat","year":"1992","unstructured":"Ezzat S, Ren SG, Braunstein GD, Melmed S: Octreotide stimulates insulin-like growth factor-binding protein-1: a potential pituitary-independent mechanism for drug action. J Clin Endocrinol Metab. 1992, 75: 1459-1463. 10.1210\/jc.75.6.1459.","journal-title":"J Clin Endocrinol Metab"},{"key":"85_CR11","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1530\/EJE-08-0822","volume":"160","author":"A Pokrajac","year":"2009","unstructured":"Pokrajac A, Frystyk J, Flyvbjerg A, Trainer P: Pituitary-independent effect of octreotide on IGF-1 generation. Eur J Endocrinol. 2009, 160: 543-548. 10.1530\/EJE-08-0822.","journal-title":"Eur J Endocrinol"},{"key":"85_CR12","doi-asserted-by":"publisher","first-page":"629","DOI":"10.2337\/diacare.25.3.629","volume":"25","author":"M Bosnak","year":"2002","unstructured":"Bosnak M, Dikici B, Dogru O, Davutoglu M, Haspolat K: Somatostatin therapy in the management of resistant diabetic ketoacidosis. Letter. Diabetes Care. 2002, 25: 629-630. 10.2337\/diacare.25.3.629.","journal-title":"Diabetes Care"},{"key":"85_CR13","doi-asserted-by":"publisher","first-page":"1152","DOI":"10.2337\/diab.36.10.1152","volume":"36","author":"EW Glaser","year":"1987","unstructured":"Glaser EW, Goldstein S, Phillips LS: Nutrition and somatomedin. XVII. Circulating somatomedin C during treatment of diabetic ketoacidosis. Diabetes. 1987, 36: 1152-1160. 10.2337\/diabetes.36.10.1152.","journal-title":"Diabetes"},{"key":"85_CR14","doi-asserted-by":"publisher","first-page":"1312","DOI":"10.1210\/jc.80.4.1312","volume":"80","author":"A Bereket","year":"1995","unstructured":"Bereket A, Lang CH, Blethen SL, Gelato MC, Fan J, Frost RA, Wilson TA: Effect of insulin on the IGF system in children with new onset insulin dependent diabetes mellitus. J Clin Endocrinol Metab. 1995, 80: 1312-1317. 10.1210\/jc.80.4.1312.","journal-title":"J Clin Endocrinol Metab"},{"key":"85_CR15","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1111\/j.1399-543X.2006.00156.x","volume":"2","author":"NS Glaser","year":"2006","unstructured":"Glaser NS, Wooton-Gorges SL, Buonocore MH, Marcin JP, Rewers A, Strain J, DiCarlo J, Neely EK, Barnes P, Kuppermann N: Frequency of sub-clinical cerebral edema in children with diabetic ketoacidosis. Pediatric Diabetes. 2006, 2: 75-80. 10.1111\/j.1399-543X.2006.00156.x.","journal-title":"Pediatric Diabetes"},{"key":"85_CR16","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1111\/j.1399-5448.2007.00224.x","volume":"8","author":"J Wolfsdorf","year":"2007","unstructured":"Wolfsdorf J, Craig ME, Daneman D, Dunger D, Edge J, Lee WR, Rosenbloom A, Sperling MA, Hanas R, International Society for Pediatric and Adolescent Diabetes: Diabetic ketoacidosis. Pediatr Diabetes. 2007, 8: 28-43. 10.1111\/j.1399-5448.2007.00224.x.","journal-title":"Pediatr Diabetes"},{"key":"85_CR17","doi-asserted-by":"publisher","first-page":"2002","DOI":"10.1007\/s00125-006-0363-8","volume":"49","author":"JA Edge","year":"2006","unstructured":"Edge JA, Jakes RW, Roy Y, Hawkins M, Winter D, Ford-Adams ME, Murphy NP, Bergomi A, Widmer B, Dunger DB: The UK case-control study of cerebral edema complicating diabetic ketoacidosis in children. Diabetologia. 2006, 49: 2002-2009. 10.1007\/s00125-006-0363-8.","journal-title":"Diabetologia"},{"key":"85_CR18","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1016\/S0022-3476(76)80386-1","volume":"89","author":"MM Martin","year":"1976","unstructured":"Martin MM, Martin ALA: Continuous low-dose infusion in the treatment of diabetic ketoacidosis in children. J Pediatr. 1976, 89: 560-564. 10.1016\/S0022-3476(76)80386-1.","journal-title":"J Pediatr"},{"key":"85_CR19","first-page":"212","volume":"12","author":"M Shichiri","year":"1982","unstructured":"Shichiri M, Kawamori R, Murata T, Yamasaki Y, Morishima T, Abe H: Quantification of insulin resistance and adaptive blood glucose control in diabetic ketosis and ketoacidosis by the artificial endocrine pancreas with computer algorithm for self-adaptive control. Horm Metab Res\/Supplement Series. 1982, 12: 212-215.","journal-title":"Horm Metab Res\/Supplement Series"},{"key":"85_CR20","doi-asserted-by":"publisher","first-page":"1038","DOI":"10.1210\/jcem-44-6-1038","volume":"44","author":"DS Schade","year":"1977","unstructured":"Schade DS, Eaton RP: Dose response to insulin in man: differential effects on glucose and ketone body regulation. J Endocrinol Metab. 1977, 44: 1038-1053. 10.1210\/jcem-44-6-1038.","journal-title":"J Endocrinol Metab"},{"issue":"Suppl 11","key":"85_CR21","first-page":"34","volume":"10","author":"N Datz","year":"2009","unstructured":"Datz N, Schuetz WV, Kordonouri O, Nestoris C, Hethey S, Engelcke G, Danne T: Cerebral crisis in severe diabetic ketoacidosis (DKA) despite adaequate fluid and insulin therapy. Abstract. Pediatric Diabetes. 2009, 10 (Suppl 11): 34-","journal-title":"Pediatric Diabetes"},{"key":"85_CR22","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1111\/j.1399-5448.2009.00536.x","volume":"11","author":"R Putta","year":"2010","unstructured":"Putta R, Cooke D, Subbarayan A, Odeka E, Ariyaswansa I, Bine M, Doughty I, Patel L, Amin R, North West England Paediatric Diabetes Network: Low dose (0.05 units\/kg\/h) is comparable with standard dose (0.1 units\/kg\/h) intravenous insulin infusion for the initial treatment of diabetic ketoacidosis in children with type 1 diabetes - an observational study. Pediatric Diabetes. 2010, 11: 12-17. 10.1111\/j.1399-5448.2009.00536.x.","journal-title":"Pediatric Diabetes"},{"issue":"Suppl 2","key":"85_CR23","first-page":"A 242","volume":"46","author":"ASA Khan","year":"2003","unstructured":"Khan ASA, Siddals KW, Gardener EA, Kaushal K, Tieszen KL, New JP, Gibson JM: Marked changes in insulin-like growth factor (IGF) system and the phosphorylation of insulin-like growth factor binding protein-1(IGFBP-1) during recovery from diabetic ketoacidosis (DKA). Abstract. Diabetologia. 2003, 46 (Suppl 2): A 242-","journal-title":"Diabetologia"},{"key":"85_CR24","doi-asserted-by":"publisher","first-page":"199","DOI":"10.2165\/00024677-200504040-00001","volume":"4","author":"MB Grant","year":"2005","unstructured":"Grant MB, Caballero S: The potential role of octreotide in the treatment of diabetic retinopathy. Treat Endocrinol. 2005, 4: 199-203. 10.2165\/00024677-200504040-00001.","journal-title":"Treat Endocrinol"},{"key":"85_CR25","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/j.ghir.2004.12.005","volume":"15","author":"E Chantelau","year":"2005","unstructured":"Chantelau E, Frystyk J: Progression of diabetic retinopathy during improved metabolic control may be treated with reduced insulin dosage and\/or somatostatin analogue administration - a case report. Growth Hormone & IGF Research. 2005, 15: 130-135.","journal-title":"Growth Hormone & IGF Research"}],"container-title":["Diabetology & Metabolic Syndrome"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1758-5996-2-56.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1758-5996-2-56\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1758-5996-2-56.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,23]],"date-time":"2019-01-23T03:12:15Z","timestamp":1548213135000},"score":1,"resource":{"primary":{"URL":"https:\/\/dmsjournal.biomedcentral.com\/articles\/10.1186\/1758-5996-2-56"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8,19]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["85"],"URL":"https:\/\/doi.org\/10.1186\/1758-5996-2-56","relation":{},"ISSN":["1758-5996"],"issn-type":[{"value":"1758-5996","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,8,19]]},"article-number":"56"}}