{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T19:27:26Z","timestamp":1771529246645,"version":"3.50.1"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ital J Pediatr"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>The incidence of severe acute respiratory tract infections in children caused by <jats:italic>Mycoplasma pneumoniae<\/jats:italic> (syn. <jats:italic>Schizoplasma pneumoniae<\/jats:italic>) and <jats:italic>Chlamydophila pneumoniae<\/jats:italic> (<jats:italic>formerly Chlamydia pneumoniae<\/jats:italic>) varies greatly from year to year and place to place around the world. This study investigated the epidemiology of <jats:italic>M<\/jats:italic>. <jats:italic>pneumoniae<\/jats:italic> and <jats:italic>C<\/jats:italic>. <jats:italic>pneumoniae<\/jats:italic> infections among children hospitalized with acute respiratory infections in Suzhou, China in the year 2006, and associations between incidence rates and climatic conditions.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>Nasopharyngeal aspirates obtained from 1598 patients (aged 26.4\u2009\u00b1\u200928.3 months; range, 1 month to 13 years) were analyzed with real-time PCR and ELISA. Meteorological data were obtained from the weather bureau.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>About 18.5% of patients were infected with <jats:italic>M<\/jats:italic>. <jats:italic>pneumoniae<\/jats:italic> and, <jats:italic>C<\/jats:italic>. <jats:italic>pneumoniae<\/jats:italic>, or both. Isolated <jats:italic>M<\/jats:italic>. <jats:italic>pneumoniae<\/jats:italic> infection was positively correlated with increasing age (\u03c7<jats:sup>2<\/jats:sup>\u2009=\u200934.76, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001). Incidence of <jats:italic>M<\/jats:italic>. <jats:italic>pneumoniae<\/jats:italic> infection was seasonal with a peak in summer (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001) and minimum in winter (<jats:italic>P<\/jats:italic>\u2009=\u20090.0001), whereas <jats:italic>C<\/jats:italic>. <jats:italic>pneumoniae<\/jats:italic> infection was low only in autumn (<jats:italic>P<\/jats:italic>\u2009=\u20090.02). Monthly mean temperature was strongly correlated with the incidence of <jats:italic>M<\/jats:italic>. <jats:italic>pneumoniae<\/jats:italic> infection (<jats:italic>r<\/jats:italic>\u2009=\u20090.825, <jats:italic>P<\/jats:italic>\u2009=\u20090.001).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>\n              <jats:italic>M<\/jats:italic>. <jats:italic>pneumoniae<\/jats:italic> and <jats:italic>C<\/jats:italic>. <jats:italic>pneumoniae<\/jats:italic> are important infectious agents in hospitalized children with acute respiratory tract infections. <jats:italic>M<\/jats:italic>. <jats:italic>pneumoniae<\/jats:italic> infection showed a strong direct correlation with environmental temperature.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1824-7288-39-34","type":"journal-article","created":{"date-parts":[[2013,5,25]],"date-time":"2013-05-25T10:14:39Z","timestamp":1369476879000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Epidemiology and associations with climatic conditions of Mycoplasma pneumoniae and Chlamydophila pneumoniae infections among Chinese children hospitalized with acute respiratory infections"],"prefix":"10.1186","volume":"39","author":[{"given":"Zhengrong","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Ji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuqing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongdong","family":"Yan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuejun","family":"Shao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,5,25]]},"reference":[{"key":"295_CR1","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1186\/1471-2164-11-181","volume":"11","author":"G D'Auria","year":"2010","unstructured":"D'Auria G, Jim\u00e9nez-Hern\u00e1ndez N, Peris-Bondia F, Moya A, Latorre A: Legionella pneumophila pangenome reveals strain-specific virulence factors. 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