{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T09:59:25Z","timestamp":1781603965850,"version":"3.54.5"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ital J Pediatr"],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1186\/1824-7288-39-78","type":"journal-article","created":{"date-parts":[[2013,12,13]],"date-time":"2013-12-13T17:00:59Z","timestamp":1386954059000},"source":"Crossref","is-referenced-by-count":36,"title":["Childhood asthma and vitamin D deficiency in Turkey: is there cause and effect relationship between them?"],"prefix":"10.1186","volume":"39","author":[{"given":"Metin","family":"Uysalol","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Levent Cem","family":"Mutlu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gamze Varol","family":"Saracoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erkut","family":"Karasu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Savas","family":"Guzel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Semra","family":"Kayaoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nedret","family":"Uzel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,12,13]]},"reference":[{"key":"334_CR1","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1093\/jn\/135.2.279","volume":"135","author":"S Hatun","year":"2005","unstructured":"Hatun S, Ozkan B, Orbak Z, Doneray H, Cizmecioglu F, Toprak D, Calikoglu AS: Vitamin D deficiency in early infancy. The Journal of nutrition. 2005, 135: 279-282.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15671226\n                    \n                  ,","journal-title":"The Journal of nutrition"},{"key":"334_CR2","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/S0899-9007(01)00724-9","volume":"18","author":"N Andiran","year":"2002","unstructured":"Andiran N, Yordam N, Ozon A: Risk factors for vitamin D deficiency in breast-fed newborns and their mothers. Nutrition. 2002, 18: 47-50. 10.1016\/S0899-9007(01)00724-9.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11827764\n                    \n                  ,","journal-title":"Nutrition"},{"key":"334_CR3","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1056\/NEJMra070553","volume":"357","author":"MF Holick","year":"2007","unstructured":"Holick MF: Vitamin D deficiency. The New England journal of medicine. 2007, 357: 266-281. 10.1056\/NEJMra070553.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17634462\n                    \n                  ,","journal-title":"The New England journal of medicine"},{"key":"334_CR4","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/j.annepidem.2007.12.001","volume":"19","author":"MF Holick","year":"2009","unstructured":"Holick MF: Vitamin D status: measurement, interpretation, and clinical application. Annals of epidemiology. 2009, 19: 73-78. 10.1016\/j.annepidem.2007.12.001.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18329892\n                    \n                  ,","journal-title":"Annals of epidemiology"},{"key":"334_CR5","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1093\/ajcn\/85.3.788","volume":"85","author":"CA Camargo Jr","year":"2007","unstructured":"Camargo CA, Rifas-Shiman SL, Litonjua AA, Rich-Edwards JW, Weiss ST, Gold DR, Kleinman K, Gillman MW: Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 y of age. The American journal of clinical nutrition. 2007, 85: 788-795.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17344501\n                    \n                  ,","journal-title":"The American journal of clinical nutrition"},{"key":"334_CR6","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1164\/rccm.200808-1361OC","volume":"179","author":"JM Brehm","year":"2009","unstructured":"Brehm JM, Celedon JC, Soto-Quiros ME, Avila L, Hunninghake GM, Forno E, Laskey D, Sylvia JS, Hollis BW, Weiss ST, Litonjua AA: Serum vitamin D levels and markers of severity of childhood asthma in Costa Rica. Am J Respir Crit Care Med. 2009, 179: 765-771. 10.1164\/rccm.200808-1361OC.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19179486\n                    \n                  ,","journal-title":"Am J Respir Crit Care Med"},{"key":"334_CR7","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.2310\/JIM.0b013e31822a234a","volume":"59","author":"LE Staple","year":"2011","unstructured":"Staple LE, Teach SJ: Evidence for the role of inadequate vitamin D in asthma severity among children. J Investig Med. 2011, 59: 1086-1088.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21804406\n                    \n                  ,","journal-title":"J Investig Med"},{"key":"334_CR8","doi-asserted-by":"publisher","first-page":"948","DOI":"10.1016\/j.jpeds.2009.12.033","volume":"156","author":"RJ Freishtat","year":"2010","unstructured":"Freishtat RJ, Iqbal SF, Pillai DK, Klein CJ, Ryan LM, Benton AS, Teach SJ: High prevalence of vitamin D deficiency among inner-city African American youth with asthma in Washington, DC. J Pediatr. 2010, 156: 948-952. 10.1016\/j.jpeds.2009.12.033.\n                    http:\/\/ac.els-cdn.com\/S0022347609012906\/1-s2.0-S0022347609012906-main.pdf?_tid=7ee726ad3b70f7e8cd8adbe00765d3ab&acdnat=1333743586_26aec9e4e97a967c8d24dcfa81ca2897\n                    \n                  ,","journal-title":"J Pediatr"},{"key":"334_CR9","doi-asserted-by":"publisher","first-page":"251","DOI":"10.4168\/aair.2011.3.4.251","volume":"3","author":"S Alyasin","year":"2011","unstructured":"Alyasin S, Momen T, Kashef S, Alipour A, Amin R: The relationship between serum 25 hydroxy vitamin d levels and asthma in children. Allergy, asthma & immunology research. 2011, 3: 251-325. 10.4168\/aair.2011.3.4.251.\n                    http:\/\/synapse.koreamed.org\/Synapse\/Data\/PDFData\/0166AAIR\/aair-3-251.pdf\n                    \n                  ,","journal-title":"Allergy, asthma & immunology research"},{"key":"334_CR10","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1159\/000323941","volume":"157","author":"A Bener","year":"2012","unstructured":"Bener A, Ehlayel MS, Tulic MK, Hamid Q: Vitamin D deficiency as a strong predictor of asthma in children. Int Arch Allergy Immunol. 2012, 157: 168-175. 10.1159\/000323941.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21986034\n                    \n                  ,","journal-title":"Int Arch Allergy Immunol"},{"key":"334_CR11","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1164\/rccm.201203-0431OC","volume":"186","author":"JM Brehm","year":"2012","unstructured":"Brehm JM, Acosta-Perez E, Klei L, Roeder K, Barmada M, Boutaoui N, Forno E, Kelly R, Paul K, Sylvia J, Litonjua AA, Cabana M, Alvarez M, Colon-Semidey A, Canino G, Celedon JC: Vitamin D insufficiency and severe asthma exacerbations in Puerto Rican children. Am J Respir Crit Care Med. 2012, 186: 140-146. 10.1164\/rccm.201203-0431OC.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22652028\n                    \n                  ,","journal-title":"Am J Respir Crit Care Med"},{"key":"334_CR12","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.jaci.2010.03.043","volume":"126","author":"JM Brehm","year":"2010","unstructured":"Brehm JM, Schuemann B, Fuhlbrigge AL, Hollis BW, Strunk RC, Zeiger RS, Weiss ST, Litonjua AA: Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study. J Allergy Clin Immunol. 2010, 126: 52-58 e5. 10.1016\/j.jaci.2010.03.043.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20538327\n                    \n                  ,","journal-title":"J Allergy Clin Immunol"},{"key":"334_CR13","doi-asserted-by":"publisher","first-page":"995","DOI":"10.1016\/j.jaci.2010.03.008","volume":"125","author":"DA Searing","year":"2010","unstructured":"Searing DA, Zhang Y, Murphy JR, Hauk PJ, Goleva E, Leung DY: Decreased serum vitamin D levels in children with asthma are associated with increased corticosteroid use. J Allergy Clin Immunol. 2010, 125: 995-1000. 10.1016\/j.jaci.2010.03.008.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20381849\n                    \n                  ,","journal-title":"J Allergy Clin Immunol"},{"key":"334_CR14","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1016\/j.jpeds.2010.08.043","volume":"158","author":"I Chinellato","year":"2011","unstructured":"Chinellato I, Piazza M, Sandri M, Peroni D, Piacentini G, Boner AL: Vitamin D serum levels and markers of asthma control in Italian children. J Pediatr. 2011, 158: 437-441. 10.1016\/j.jpeds.2010.08.043.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20870246\n                    \n                  ,","journal-title":"J Pediatr"},{"key":"334_CR15","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1001\/archinternmed.2008.560","volume":"169","author":"AA Ginde","year":"2009","unstructured":"Ginde AA, Mansbach JM, Camargo CA: Association between serum 25-hydroxyvitamin D level and upper respiratory tract infection in the Third National Health and Nutrition Examination Survey. Arch Intern Med. 2009, 169: 384-390. 10.1001\/archinternmed.2008.560.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19237723\n                    \n                  ,","journal-title":"Arch Intern Med"},{"key":"334_CR16","doi-asserted-by":"publisher","first-page":"1255","DOI":"10.3945\/ajcn.2009.29094","volume":"91","author":"M Urashima","year":"2010","unstructured":"Urashima M, Segawa T, Okazaki M, Kurihara M, Wada Y, Ida H: Randomized trial of vitamin D supplementation to prevent seasonal influenza A in schoolchildren. Am J Clin Nutr. 2010, 91: 1255-1260. 10.3945\/ajcn.2009.29094.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20219962\n                    \n                  ,","journal-title":"Am J Clin Nutr"},{"key":"334_CR17","doi-asserted-by":"publisher","first-page":"137","DOI":"10.4161\/derm.20434","volume":"4","author":"SD Brown","year":"2012","unstructured":"Brown SD, Calvert HH, Fitzpatrick AM: Vitamin D and asthma. Dermato-endocrinology. 2012, 4: 137-145. 10.4161\/derm.20434.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22928069\n                    \n                  ,","journal-title":"Dermato-endocrinology"},{"key":"334_CR18","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1016\/j.prrv.2011.07.003","volume":"13","author":"A Gupta","year":"2012","unstructured":"Gupta A, Bush A, Hawrylowicz C, Saglani S: Vitamin D and asthma in children. Paediatr Respir Rev. 2012, 13: 236-243. 10.1016\/j.prrv.2011.07.003.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23069123\n                    \n                  ,","journal-title":"Paediatr Respir Rev"},{"key":"334_CR19","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1183\/09031936.00138707","volume":"31","author":"ED Bateman","year":"2008","unstructured":"Bateman ED, Hurd SS, Barnes PJ, Bousquet J, Drazen JM, FitzGerald M, Gibson P, Ohta K, O\u2019Byrene P, Pedersen SE, Pizzichini E, Sullivan SD, Wenzel SE, Zar HJ: Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J. 2008, 31: 143-178. 10.1183\/09031936.00138707.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18166595\n                    \n                  ,","journal-title":"Eur Respir J"},{"key":"334_CR20","doi-asserted-by":"publisher","first-page":"353","DOI":"10.4065\/81.3.353","volume":"81","author":"MF Holick","year":"2006","unstructured":"Holick MF: High prevalence of vitamin D inadequacy and implications for health. Mayo Clin Proc. 2006, 81: 353-373. 10.4065\/81.3.353.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16529140\n                    \n                  ,","journal-title":"Mayo Clin Proc"},{"key":"334_CR21","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1542\/peds.2007-1894","volume":"122","author":"M Misra","year":"2008","unstructured":"Misra M, Pacaud D, Petryk A, Collett-Solberg PF, Kappy M: Vitamin D deficiency in children and its management: review of current knowledge and recommendations. Pediatrics. 2008, 122: 398-417. 10.1542\/peds.2007-1894.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18676559\n                    \n                  ,","journal-title":"Pediatrics"},{"key":"334_CR22","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1186\/1475-2891-12-81","volume":"12","author":"S Bose","year":"2013","unstructured":"Bose S, Breysse PN, McCormack MC, Hansel NN, Rusher RR, Matsui E, Peng R, Curtin-Brosnan J, Diette GB: Outdoor exposure and vitamin D levels in urban children with asthma. Nutr J. 2013, 12: 81-87. 10.1186\/1475-2891-12-81.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23758744\n                    \n                  ,","journal-title":"Nutr J"},{"key":"334_CR23","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1186\/1824-7288-39-35","volume":"4","author":"F Cadario","year":"2013","unstructured":"Cadario F, Savastio S, Pozzi E, Capelli A, Dondi E, Gatto M, Zaffaroni M, Bona G: Vitamin D status in cord blood and newborns: ethnic differences. Ital J Pediatr. 2013, 4: 35-39.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23735116\n                    \n                  ,","journal-title":"Ital J Pediatr"},{"key":"334_CR24","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1016\/j.pharmthera.2013.06.006","volume":"140","author":"AH Poon","year":"2013","unstructured":"Poon AH, Mahboub B, Hamid Q: Vitamin D deficiency and severe asthma. Pharmacol Ther. 2013, 140: 148-155. 10.1016\/j.pharmthera.2013.06.006.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23792089\n                    \n                  ,","journal-title":"Pharmacol Ther"},{"key":"334_CR25","doi-asserted-by":"publisher","first-page":"2130","DOI":"10.1210\/jc.2006-2250","volume":"92","author":"N Binkley","year":"2007","unstructured":"Binkley N, Novotny R, Krueger D, Kawahara T, Daida YG, Lensmeyer G, Hollis BW, Drezner MK: Low vitamin D status despite abundant sun exposure. J Clin Endocr Metab. 2007, 92: 2130-2135. 10.1210\/jc.2006-2250.\n                    http:\/\/jcem.endojournals.org\/content\/92\/6\/2130.full.pdf\n                    \n                  ,","journal-title":"J Clin Endocr Metab"},{"key":"334_CR26","doi-asserted-by":"publisher","first-page":"1342","DOI":"10.1164\/rccm.201107-1239OC","volume":"184","author":"A Gupta","year":"2011","unstructured":"Gupta A, Sjoukes A, Richards D, Banya W, Hawrylowicz C, Bush A, Saglani S: Relationship between serum vitamin D, disease severity, and airway remodeling in children with asthma. Am J Respir Crit Care Med. 2011, 184: 1342-1349. 10.1164\/rccm.201107-1239OC.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21908411\n                    \n                  ,","journal-title":"Am J Respir Crit Care Med"},{"key":"334_CR27","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1016\/j.jada.2011.01.004","volume":"111","author":"AC Ross","year":"2011","unstructured":"Ross AC, Manson JE, Abrams SA, Aloia JF, Brannon PM, Clinton SK, Durazo-Arvizu RA, Gallagher JC, Galio RL, Jones G, Kovacs CS, Mayne ST, Rosen CJ, Shapses SR: The 2011 Dietary Reference Intakes for Calcium and Vitamin D: what dietetics practitioners need to know. J Am Diet Assoc. 2011, 111: 524-527. 10.1016\/j.jada.2011.01.004.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21118827\n                    \n                  ,","journal-title":"J Am Diet Assoc"},{"key":"334_CR28","doi-asserted-by":"publisher","first-page":"1366","DOI":"10.1183\/09031936.00044710","volume":"37","author":"I Chinellato","year":"2011","unstructured":"Chinellato I, Piazza M, Sandri M, Peroni DG, Cardinale F, Piacentini GL, Boner AL: Serum vitamin D levels and exercise-induced bronchoconstriction in children with asthma. Eur Respir J. 2011, 37: 1366-1370. 10.1183\/09031936.00044710.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21071468\n                    \n                  ,","journal-title":"Eur Respir J"},{"key":"334_CR29","doi-asserted-by":"publisher","first-page":"150","DOI":"10.2174\/187152807781696437","volume":"6","author":"M Corradi","year":"2007","unstructured":"Corradi M, Zinelli C, Caffarelli C: Exhaled breath biomarkers in asthmatic children. Inflamm Allergy Drug Targets. 2007, 6: 150-159. 10.2174\/187152807781696437.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17897051\n                    \n                  ,","journal-title":"Inflamm Allergy Drug Targets"},{"key":"334_CR30","first-page":"38","volume":"31","author":"A Manna","year":"2012","unstructured":"Manna A, Caffarelli C, Varini M, Povesi Dascola C, Montella S, Maglione M, Sperl\u00ec F, Santamaria F: Clinical application of exhaled nitric oxide measurement in pediatric lung diseases. Ital J Pediatr. 2012, 31: 38-74.\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23273317\n                    \n                  ,","journal-title":"Ital J Pediatr"}],"container-title":["Italian Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1824-7288-39-78.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1824-7288-39-78\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1824-7288-39-78.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,21]],"date-time":"2019-01-21T13:44:05Z","timestamp":1548078245000},"score":1,"resource":{"primary":{"URL":"https:\/\/ijponline.biomedcentral.com\/articles\/10.1186\/1824-7288-39-78"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["334"],"URL":"https:\/\/doi.org\/10.1186\/1824-7288-39-78","relation":{},"ISSN":["1824-7288"],"issn-type":[{"value":"1824-7288","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12]]},"article-number":"78"}}