{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T14:30:38Z","timestamp":1787236238917,"version":"build-2736575974"},"reference-count":6,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Ophthal Inflamm Infect"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>We report a case of bacterial endophthalmitis caused by an intraocular cilium in a patient without any history of trauma or ocular surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings<\/jats:title>\n                    <jats:p>\n                      A 32-year-old Caucasian male showed symptoms of orbital myositis and scleritis, with no intraocular inflammation in the right eye. The patient had been treated with infliximab for Crohn\u2019s disease. Three weeks after initiation of oral prednisolone therapy, he developed bacterial endophthalmitis. During pars plana vitrectomy, a cilium in the massive vitreous opacity was found. A focal scleral necrosis was detected just outside where the cilium was intraoperatively observed. Vitreous culture showed the presence of\n                      <jats:italic>Staphylococcus aureus<\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The intraocular cilium seemed to be the aetiology of the endophthalmitis in this case, which suggests that anti-tumour necrosis factor-\u03b1 therapy may play a role in the migration of cilia into the globe and the occurrence of endophthalmitis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/1869-5760-3-50","type":"journal-article","created":{"date-parts":[[2013,6,5]],"date-time":"2013-06-05T18:38:58Z","timestamp":1370457538000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Bacterial endophthalmitis caused by an intraocular cilium in a patient under treatment with infliximab"],"prefix":"10.1186","volume":"3","author":[{"given":"Xue-hai","family":"Jin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenichi","family":"Namba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wataru","family":"Saito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daiju","family":"Iwata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susumu","family":"Ishida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,6,5]]},"reference":[{"issue":"2","key":"49_CR1","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1111\/j.1600-0420.1996.tb00072.x","volume":"74","author":"AK Gupta","year":"1996","unstructured":"Gupta AK, Ghosh B, Mazumdar S, Gupta A: An unusual intraocular foreign body. Acta Ophthalmol Scand 1996,74(2):200\u2013201.","journal-title":"Acta Ophthalmol Scand"},{"issue":"3","key":"49_CR2","doi-asserted-by":"crossref","first-page":"243","DOI":"10.3928\/1542-8877-19960301-14","volume":"27","author":"KT Oh","year":"1996","unstructured":"Oh KT, Singerman LJ: An eyelash in the vitreous cavity without apparent etiology. Ophthalmic Surg Lasers 1996,27(3):243\u2013245.","journal-title":"Ophthalmic Surg Lasers"},{"issue":"3","key":"49_CR3","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1016\/S0008-4182(04)80126-1","volume":"39","author":"PJ Kertes","year":"2004","unstructured":"Kertes PJ, Al-Ghamdi AA, Brownstein S, Coupal D, Gilberg S, Britton WA Jr: An intraocular cilium of uncertain origin. Can J Ophthalmol 2004,39(3):279\u2013281.","journal-title":"Can J Ophthalmol"},{"issue":"3","key":"49_CR4","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1055\/s-2005-858106","volume":"222","author":"MG Wirth","year":"2005","unstructured":"Wirth MG, Helbig H: Can eyelashes migrate? Klin Monbl Augenheilkd 2005,222(3):238\u2013240. 10.1055\/s-2005-858106","journal-title":"Klin Monbl Augenheilkd"},{"issue":"10","key":"49_CR5","doi-asserted-by":"publisher","first-page":"1285","DOI":"10.1016\/S1286-4579(00)01282-X","volume":"2","author":"D Schluter","year":"2000","unstructured":"Schluter D, Deckert M: The divergent role of tumor necrosis factor receptors in infectious diseases. Microbes Infect 2000,2(10):1285\u20131292. 10.1016\/S1286-4579(00)01282-X","journal-title":"Microbes Infect"},{"issue":"9","key":"49_CR6","doi-asserted-by":"publisher","first-page":"e88","DOI":"10.1086\/425123","volume":"39","author":"G Haerter","year":"2004","unstructured":"Haerter G, Manfras BJ, de Jong-Hesse Y, Wilts H, Mertens T, Kern P, Schmitt M: Cytomegalovirus retinitis in a patient treated with anti-tumor necrosis factor alpha antibody therapy for rheumatoid arthritis. Clin Infect Dis 2004,39(9):e88-e94. 10.1086\/425123","journal-title":"Clin Infect Dis"}],"container-title":["Journal of Ophthalmic Inflammation and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1869-5760-3-50.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T15:57:24Z","timestamp":1630511844000},"score":1,"resource":{"primary":{"URL":"https:\/\/joii-journal.springeropen.com\/articles\/10.1186\/1869-5760-3-50"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6,5]]},"references-count":6,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["49"],"URL":"https:\/\/doi.org\/10.1186\/1869-5760-3-50","relation":{},"ISSN":["1869-5760"],"issn-type":[{"value":"1869-5760","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6,5]]},"assertion":[{"value":"10 April 2013","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 May 2013","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 June 2013","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"50"}}