{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T00:41:49Z","timestamp":1649119309895},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Ophthal Inflamm Infect"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>\n              <jats:italic>Candida dubliniensis<\/jats:italic> is a recently described opportunistic fungal pathogen that rarely infects the eye. Reported cases of <jats:italic>C. dubliniensis<\/jats:italic> endophthalmitis have been of endogenous etiology and demonstrated recovery of visual acuity with timely treatment. We herein report an unusual case of severe <jats:italic>C. dubliniensis<\/jats:italic> endophthalmitis requiring enucleation.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Findings<\/jats:title>\n            <jats:p>This is a retrospective, descriptive case report with a brief literature review. A 41-year-old Caucasian man, with a history of blunt trauma 8 months prior, presented to the emergency department with left eye pain and loss of vision 2 days after complicated cataract surgery. He was first evaluated by an outside ophthalmologist 3 months after trauma for left eye pain and progressive vision loss. He was found to have light perception vision with non-granulomatous anterior uveitis but no sign of ruptured globe. A dense cataract developed while he was treated with topical and subtenon's corticosteroids for which he underwent cataract surgery. Our examination revealed no light perception vision with a relative afferent pupillary defect, elevated intraocular pressure, moderate anterior chamber reaction, pupillary membrane, vitritis, and choroidal thickening on B-scan ultrasonography. Diagnostic vitrectomy revealed purulent vitreal debris, retinal detachment with severe retinal necrosis, and choroidal infiltrates. Operative fungal cultures grew <jats:italic>C. dubliniensis<\/jats:italic>. Despite intravitreal and systemic anti-fungal treatment, vision and pain did not improve, resulting in subsequent enucleation.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>\n              <jats:italic>C. dubliniensis<\/jats:italic> endophthalmitis is uncommonly encountered and typically has reasonable visual outcomes. This is the first reported case of <jats:italic>C. dubliniensis<\/jats:italic>, likely exogenous endophthalmitis, resulting in enucleation, illustrating the potential virulence of this newly described organism.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1869-5760-4-11","type":"journal-article","created":{"date-parts":[[2014,5,2]],"date-time":"2014-05-02T13:01:31Z","timestamp":1399035691000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Rare case of exogenous Candida dubliniensis endophthalmitis: a case report and brief review of the literature"],"prefix":"10.1186","volume":"4","author":[{"given":"Brian Douglas","family":"McMillan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary James","family":"Miller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,5,2]]},"reference":[{"key":"75_CR1","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1016\/j.ajo.2011.06.020","volume":"153","author":"A Lingappan","year":"2012","unstructured":"Lingappan A, Wykoff CC, Albini TA: Endogenous fungal endophthalmitis: causative organisms, management strategies, and visual acuity outcomes. 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