{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:22:38Z","timestamp":1787019758324,"version":"build-2736575974"},"reference-count":64,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2010,4,6]],"date-time":"2010-04-06T00:00:00Z","timestamp":1270512000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp &amp; Trans Stroke Med"],"published-print":{"date-parts":[[2010,12]]},"DOI":"10.1186\/2040-7378-2-8","type":"journal-article","created":{"date-parts":[[2010,4,7]],"date-time":"2010-04-07T02:28:48Z","timestamp":1270607328000},"source":"Crossref","is-referenced-by-count":6,"title":["Neuronal precursor cell proliferation in the hippocampus after transient cerebral ischemia: a comparative study of two rat strains using stereological tools"],"prefix":"10.1186","volume":"2","author":[{"given":"Jesper","family":"Kelsen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne H","family":"Larsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens Christian","family":"S\u00f8rensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arne","family":"M\u00f8ller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f8rgen","family":"Fr\u00f8ki\u00e6r","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00f8ren","family":"Nielsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens R","family":"Nyengaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens D","family":"Mikkelsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars Christian B","family":"R\u00f8nn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,4,6]]},"reference":[{"key":"16_CR1","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1097\/00004647-199908000-00001","volume":"19","author":"FC Barone","year":"1999","unstructured":"Barone FC, Feuerstein GZ: Inflammatory mediators and stroke: new opportunities for novel therapeutics. J Cereb Blood Flow Metab 1999, 19: 819\u2013834. 10.1097\/00004647-199908000-00001","journal-title":"J Cereb Blood Flow Metab"},{"key":"16_CR2","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1038\/35094583","volume":"2","author":"SM Allan","year":"2001","unstructured":"Allan SM, Rothwell NJ: Cytokines and acute neurodegeneration. Nat Rev Neurosci 2001, 2: 734\u2013744. 10.1038\/35094583","journal-title":"Nat Rev Neurosci"},{"key":"16_CR3","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1038\/nri1664","volume":"5","author":"SM Allan","year":"2005","unstructured":"Allan SM, Tyrrell PJ, Rothwell NJ: Interleukin-1 and neuronal injury. Nat Rev Immunol 2005, 5: 629\u2013640. 10.1038\/nri1664","journal-title":"Nat Rev Immunol"},{"key":"16_CR4","doi-asserted-by":"publisher","first-page":"1750","DOI":"10.2741\/1920","volume":"11","author":"G Feuerstein","year":"2006","unstructured":"Feuerstein G: Inflammation and stroke: therapeutic effects of adenoviral expression of secretory Leukocyte Protease Inhibitor. Front Biosci 2006, 11: 1750\u20131757. 10.2741\/1920","journal-title":"Front Biosci"},{"key":"16_CR5","first-page":"644","volume":"10","author":"E Candelario-Jalil","year":"2009","unstructured":"Candelario-Jalil E: Injury and repair mechanisms in ischemic stroke: considerations for the development of novel neurotherapeutics. Curr Opin Investig Drugs 2009, 10: 644\u2013654.","journal-title":"Curr Opin Investig Drugs"},{"key":"16_CR6","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1038\/nm747","volume":"8","author":"A Arvidsson","year":"2002","unstructured":"Arvidsson A, Collin T, Kirik D, Kokaia Z, Lindvall O: Neuronal replacement from endogenous precursors in the adult brain after stroke. Nat Med 2002, 8: 963\u2013970. 10.1038\/nm747","journal-title":"Nat Med"},{"key":"16_CR7","doi-asserted-by":"publisher","first-page":"11839","DOI":"10.1073\/pnas.0404474101","volume":"101","author":"S Kelly","year":"2004","unstructured":"Kelly S, Bliss TM, Shah AK, Sun GH, Ma M, Foo WC, Masel J, Yenari MA, Weissman IL, Uchida N, et al.: Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex. Proc Natl Acad Sci USA 2004, 101: 11839\u201311844. 10.1073\/pnas.0404474101","journal-title":"Proc Natl Acad Sci USA"},{"key":"16_CR8","doi-asserted-by":"publisher","first-page":"I69","DOI":"10.1161\/01.HYP.6.2_Pt_2.I69","volume":"6","author":"P Coyle","year":"1984","unstructured":"Coyle P: Outcomes to middle cerebral artery occlusion in hypertensive and normotensive rats. Hypertension 1984, 6: I69-I74.","journal-title":"Hypertension"},{"key":"16_CR9","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1038\/jcbfm.1988.88","volume":"8","author":"S Brint","year":"1988","unstructured":"Brint S, Jacewicz M, Kiessling M, Tanabe J, Pulsinelli W: Focal Brain Ischemia in the Rat - Methods for Reproducible Neocortical Infarction Using Tandem Occlusion of the Distal Middle Cerebral and Ipsilateral Common Carotid Arteries. Journal of Cerebral Blood Flow and Metabolism 1988, 8: 474\u2013485.","journal-title":"Journal of Cerebral Blood Flow and Metabolism"},{"key":"16_CR10","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/S0149-7634(05)80182-4","volume":"16","author":"FC Barone","year":"1992","unstructured":"Barone FC, Price WJ, White RF, Willette RN, Feuerstein GZ: Genetic hypertension and increased susceptibility to cerebral ischemia. Neurosci Biobehav Rev 1992, 16: 219\u2013233. 10.1016\/S0149-7634(05)80182-4","journal-title":"Neurosci Biobehav Rev"},{"key":"16_CR11","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1161\/01.STR.17.3.520","volume":"17","author":"P Coyle","year":"1986","unstructured":"Coyle P: Different susceptibilities to cerebral infarction in spontaneously hypertensive (SHR) and normotensive Sprague-Dawley rats. Stroke 1986, 17: 520\u2013525.","journal-title":"Stroke"},{"key":"16_CR12","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1161\/01.STR.14.4.605","volume":"14","author":"P Coyle","year":"1983","unstructured":"Coyle P, Jokelainen PT: Differential outcome to middle cerebral artery occlusion in spontaneously hypertensive stroke-prone rats (SHRSP) and Wistar Kyoto (WKY) rats. Stroke 1983, 14: 605\u2013611.","journal-title":"Stroke"},{"key":"16_CR13","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1097\/00004872-198805000-00011","volume":"6","author":"M Grabowski","year":"1988","unstructured":"Grabowski M, Nordborg C, Brundin P, Johansson BB: Middle cerebral artery occlusion in the hypertensive and normotensive rat: a study of histopathology and behaviour. J Hypertens 1988, 6: 405\u2013411. 10.1097\/00004872-198805000-00011","journal-title":"J Hypertens"},{"key":"16_CR14","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1097\/00004647-200103000-00004","volume":"21","author":"E Perfilieva","year":"2001","unstructured":"Perfilieva E, Risedal A, Nyberg J, Johansson BB, Eriksson PS: Gender and strain influence on neurogenesis in dentate gyrus of young rats. J Cereb Blood Flow Metab 2001, 21: 211\u2013217. 10.1097\/00004647-200103000-00004","journal-title":"J Cereb Blood Flow Metab"},{"key":"16_CR15","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1161\/01.HYP.38.1.116","volume":"38","author":"L Marks","year":"2001","unstructured":"Marks L, Carswell HV, Peters EE, Graham DI, Patterson J, Dominiczak AF, Macrae IM: Characterization of the microglial response to cerebral ischemia in the stroke-prone spontaneously hypertensive rat. Hypertension 2001, 38: 116\u2013122.","journal-title":"Hypertension"},{"key":"16_CR16","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/0730-725X(94)00081-D","volume":"13","author":"K Kohno","year":"1995","unstructured":"Kohno K, Back T, Hoehn-Berlage M, Hossmann KA: A modified rat model of middle cerebral artery thread occlusion under electrophysiological control for magnetic resonance investigations. Magn Reson Imaging 1995, 13: 65\u201371. 10.1016\/0730-725X(94)00081-D","journal-title":"Magn Reson Imaging"},{"key":"16_CR17","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1161\/01.STR.20.1.84","volume":"20","author":"EZ Longa","year":"1989","unstructured":"Longa EZ, Weinstein PR, Carlson S, Cummins R: Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 1989, 20: 84\u201391.","journal-title":"Stroke"},{"key":"16_CR18","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1080\/01616412.1997.11740834","volume":"19","author":"GJ Zarow","year":"1997","unstructured":"Zarow GJ, Karibe H, States BA, Graham SH, Weinstein PR: Endovascular suture occlusion of the middle cerebral artery in rats: Effect of suture insertion distance on cerebral blood flow, infarct distribution and infarct volume. Neurological Research 1997, 19: 409\u2013416.","journal-title":"Neurological Research"},{"key":"16_CR19","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.brainres.2006.02.040","volume":"1085","author":"C Hundahl","year":"2006","unstructured":"Hundahl C, Kelsen J, Kjaer K, Ronn LC, Weber RE, Geuens E, Hay-Schmidt A, Nyengaard JR: Does neuroglobin protect neurons from ischemic insult? A quantitative investigation of neuroglobin expression following transient MCAo in spontaneously hypertensive rats. Brain Res 2006, 1085: 19\u201327. 10.1016\/j.brainres.2006.02.040","journal-title":"Brain Res"},{"key":"16_CR20","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1111\/j.1699-0463.1988.tb00954.x","volume":"96","author":"HJ Gundersen","year":"1988","unstructured":"Gundersen HJ, Bagger P, Bendtsen TF, Evans SM, Korbo L, Marcussen N, Moller A, Nielsen K, Nyengaard JR, Pakkenberg B, et al.: The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. APMIS 1988, 96: 857\u2013881. 10.1111\/j.1699-0463.1988.tb00954.x","journal-title":"APMIS"},{"issue":"Pt 1","key":"16_CR21","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1111\/j.1365-2818.1988.tb04609.x","volume":"151","author":"HJ Gundersen","year":"1988","unstructured":"Gundersen HJ: The nucleator. J Microsc 1988,151(Pt 1):3\u201321.","journal-title":"J Microsc"},{"issue":"Pt 3","key":"16_CR22","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1111\/j.1365-2818.1987.tb02837.x","volume":"147","author":"HJ Gundersen","year":"1987","unstructured":"Gundersen HJ, Jensen EB: The efficiency of systematic sampling in stereology and its prediction. J Microsc 1987,147(Pt 3):229\u2013263.","journal-title":"J Microsc"},{"key":"16_CR23","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/S0165-0270(98)00129-0","volume":"85","author":"JO Larsen","year":"1998","unstructured":"Larsen JO: Stereology of nerve cross sections. J Neurosci Methods 1998, 85: 107\u2013118. 10.1016\/S0165-0270(98)00129-0","journal-title":"J Neurosci Methods"},{"key":"16_CR24","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1093\/acprof:oso\/9780198505280.003.0008","volume-title":"Quantitative methods in neuroscience","author":"JR Nyengaard","year":"2004","unstructured":"Nyengaard JR, Evans SM: Section introduction. In Quantitative methods in neuroscience. 1st edition. Edited by: Evans SM, Janson AM, Nyengaard JR. Oxford University Press; 2004:185\u2013196. full_text","edition":"1"},{"key":"16_CR25","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1046\/j.1365-2818.2001.00958.x","volume":"204","author":"KA Dorph-Petersen","year":"2001","unstructured":"Dorph-Petersen KA, Nyengaard JR, Gundersen HJ: Tissue shrinkage and unbiased stereological estimation of particle number and size. J Microsc 2001, 204: 232\u2013246. 10.1046\/j.1365-2818.2001.00958.x","journal-title":"J Microsc"},{"key":"16_CR26","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1002\/ar.1092310411","volume":"231","author":"MJ West","year":"1991","unstructured":"West MJ, Slomianka L, Gundersen HJ: Unbiased stereological estimation of the total number of neurons in thesubdivisions of the rat hippocampus using the optical fractionator. Anat Rec 1991, 231: 482\u2013497. 10.1002\/ar.1092310411","journal-title":"Anat Rec"},{"key":"16_CR27","doi-asserted-by":"publisher","first-page":"2252","DOI":"10.1161\/01.STR.0000083625.54851.9A","volume":"34","author":"M Dittmar","year":"2003","unstructured":"Dittmar M, Spruss T, Schuierer G, Horn M: External carotid artery territory ischemia impairs outcome in the endovascular filament model of middle cerebral artery occlusion in rats. Stroke 2003, 34: 2252\u20132257. 10.1161\/01.STR.0000083625.54851.9A","journal-title":"Stroke"},{"key":"16_CR28","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1186\/1742-2094-3-31","volume":"3","author":"J Kelsen","year":"2006","unstructured":"Kelsen J, Kjaer K, Chen G, Pedersen M, Rohl L, Frokiaer J, Nielsen S, Nyengaard JR, Ronn LC: Parecoxib is neuroprotective in spontaneously hypertensive rats after transient middle cerebral artery occlusion: a divided treatment response? J Neuroinflammation 2006, 3: 31. 10.1186\/1742-2094-3-31","journal-title":"J Neuroinflammation"},{"key":"16_CR29","doi-asserted-by":"publisher","first-page":"2743","DOI":"10.1161\/01.STR.30.12.2743","volume":"30","author":"Z He","year":"1999","unstructured":"He Z, Yamawaki T, Yang S, Day AL, Simpkins JW, Naritomi H: Experimental model of small deep infarcts involving the hypothalamus in rats: changes in body temperature and postural reflex. Stroke 1999, 30: 2743\u20132751.","journal-title":"Stroke"},{"key":"16_CR30","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/S0022-510X(00)00434-2","volume":"182","author":"Z He","year":"2000","unstructured":"He Z, Yang SH, Naritomi H, Yamawaki T, Liu QL, King MA, Day AL, Simpkins JW: Definition of the anterior choroidal artery territory in rats using intraluminal occluding technique. Journal of the Neurological Sciences 2000, 182: 16\u201328. 10.1016\/S0022-510X(00)00434-2","journal-title":"Journal of the Neurological Sciences"},{"key":"16_CR31","doi-asserted-by":"publisher","DOI":"10.1093\/acprof:oso\/9780198505280.001.0001","volume-title":"Quantitative methods in neuroscience","author":"SM Evans","year":"2004","unstructured":"Evans SM, Janson AM, Nyengaard JR: Quantitative methods in neuroscience. Oxford University Press; 2004."},{"key":"16_CR32","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3995\/jstroke.8.1","volume":"8","author":"J Koizumi","year":"1986","unstructured":"Koizumi J, Yoshida Y, Nakazawa T, Ooneda G: Experimental studies of ischemic brain edema: 1. A new experimental model of cerebral embolism in rats in which recirculation can be introduced in the ischemic area. Jpn J Stroke 1986, 8: 1\u20138.","journal-title":"Jpn J Stroke"},{"key":"16_CR33","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1186\/2040-7378-1-7","volume":"1","author":"K Sicard","year":"2009","unstructured":"Sicard K, Fisher M: Animal models of focal brain ischemia. Experimental & Translational Stroke Medicine 2009, 1: 7. 10.1186\/2040-7378-1-7","journal-title":"Experimental & Translational Stroke Medicine"},{"key":"16_CR34","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1161\/01.STR.24.2.294","volume":"24","author":"RJ Laing","year":"1993","unstructured":"Laing RJ, Jakubowski J, Laing RW: Middle cerebral artery occlusion without craniectomy in rats. Which method works best? Stroke 1993, 24: 294\u2013297.","journal-title":"Stroke"},{"key":"16_CR35","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/0006-8993(95)00033-M","volume":"675","author":"HS Oliff","year":"1995","unstructured":"Oliff HS, Weber E, Eilon G, Marek P: The role of strain\/vendor differences on the outcome of focal ischemia induced by intraluminal middle cerebral artery occlusion in the rat. Brain Res 1995, 675: 20\u201326. 10.1016\/0006-8993(95)00033-M","journal-title":"Brain Res"},{"key":"16_CR36","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/S0022-510X(97)00184-6","volume":"153","author":"K Takano","year":"1997","unstructured":"Takano K, Tatlisumak T, Bergmann AG, Gibson DG III, Fisher M: Reproducibility and reliability of middle cerebral artery occlusion using a silicone-coated suture (Koizumi) in rats. J Neurol Sci 1997, 153: 8\u201311. 10.1016\/S0022-510X(97)00184-6","journal-title":"J Neurol Sci"},{"key":"16_CR37","doi-asserted-by":"publisher","first-page":"2162","DOI":"10.1161\/01.STR.29.10.2162","volume":"29","author":"R Schmid-Elsaesser","year":"1998","unstructured":"Schmid-Elsaesser R, Zausinger S, Hungerhuber E, Baethmann A, Reulen HJ: A critical reevaluation of the intraluminal thread model of focal cerebral ischemia: evidence of inadvertent premature reperfusion and subarachnoid hemorrhage in rats by laser-Doppler flowmetry. Stroke 1998, 29: 2162\u20132170.","journal-title":"Stroke"},{"key":"16_CR38","doi-asserted-by":"publisher","first-page":"2372","DOI":"10.1161\/01.STR.0000142134.37512.a7","volume":"35","author":"T Gerriets","year":"2004","unstructured":"Gerriets T, Stolz E, Walberer M, Muller C, Rottger C, Kluge A, Kaps M, Fisher M, Bachmann G: Complications and pitfalls in rat stroke models for middle cerebral artery occlusion: a comparison between the suture and the macrosphere model using magnetic resonance angiography. Stroke 2004, 35: 2372\u20132377. 10.1161\/01.STR.0000142134.37512.a7","journal-title":"Stroke"},{"key":"16_CR39","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/2040-7378-1-8","volume":"1","author":"S Braeuninger","year":"2009","unstructured":"Braeuninger S, Kleinschnitz C: Rodent models of focal cerebral ischemia: procedural pitfalls and translational problems. Experimental & Translational Stroke Medicine 2009, 1: 8. 10.1186\/2040-7378-1-8","journal-title":"Experimental & Translational Stroke Medicine"},{"key":"16_CR40","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/S0165-0270(02)00277-7","volume":"122","author":"J Woitzik","year":"2002","unstructured":"Woitzik J, Schilling L: Control of completeness and immediate detection of bleeding by a single laser-Doppler flow probe during intravascular middle cerebral artery occlusion in rats. J Neurosci Methods 2002, 122: 75\u201378. 10.1016\/S0165-0270(02)00277-7","journal-title":"J Neurosci Methods"},{"key":"16_CR41","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1179\/016164105X18214","volume":"27","author":"R Prieto","year":"2005","unstructured":"Prieto R, Carceller F, Roda JM, Avendano C: The intraluminal thread model revisited: rat strain differences in local cerebral blood flow. Neurol Res 2005, 27: 47\u201352. 10.1179\/016164105X18214","journal-title":"Neurol Res"},{"key":"16_CR42","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1002\/(SICI)1096-9861(19970929)386:3<461::AID-CNE9>3.0.CO;2-#","volume":"386","author":"E Lehrmann","year":"1997","unstructured":"Lehrmann E, Christensen T, Zimmer J, Diemer NH, Finsen B: Microglial and macrophage reactions mark progressive changes and define the penumbra in the rat neocortex and striatum after transient middle cerebral artery occlusion. J Comp Neurol 1997, 386: 461\u2013476. 10.1002\/(SICI)1096-9861(19970929)386:3<461::AID-CNE9>3.0.CO;2-#","journal-title":"J Comp Neurol"},{"key":"16_CR43","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/S0165-0173(99)00007-7","volume":"30","author":"G Raivich","year":"1999","unstructured":"Raivich G, Bohatschek M, Kloss CU, Werner A, Jones LL, Kreutzberg GW: Neuroglial activation repertoire in the injured brain: graded response, molecular mechanisms and cues to physiological function. Brain Res Brain Res Rev 1999, 30: 77\u2013105. 10.1016\/S0165-0173(99)00007-7","journal-title":"Brain Res Brain Res Rev"},{"key":"16_CR44","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1016\/0166-2236(96)10049-7","volume":"19","author":"GW Kreutzberg","year":"1996","unstructured":"Kreutzberg GW: Microglia: a sensor for pathological events in the CNS. Trends Neurosci 1996, 19: 312\u2013318. 10.1016\/0166-2236(96)10049-7","journal-title":"Trends Neurosci"},{"key":"16_CR45","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1186\/1742-2094-1-14","volume":"1","author":"WJ Streit","year":"2004","unstructured":"Streit WJ, Mrak RE, Griffin WS: Microglia and neuroinflammation: a pathological perspective. J Neuroinflammation 2004, 1: 14. 10.1186\/1742-2094-1-14","journal-title":"J Neuroinflammation"},{"key":"16_CR46","doi-asserted-by":"publisher","first-page":"1304","DOI":"10.1161\/01.STR.17.6.1304","volume":"17","author":"JB Bederson","year":"1986","unstructured":"Bederson JB, Pitts LH, Germano SM, Nishimura MC, Davis RL, Bartkowski HM: Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats. Stroke 1986, 17: 1304\u20131308.","journal-title":"Stroke"},{"key":"16_CR47","doi-asserted-by":"publisher","first-page":"840","DOI":"10.1161\/01.STR.12.6.840","volume":"12","author":"GK Rieke","year":"1981","unstructured":"Rieke GK, Bowers DE Jr, Penn P: Vascular supply pattern to rat caudatoputamen and globus pallidus: scanning electronmicroscopic study of vascular endocasts of stroke-prone vessels. Stroke 1981, 12: 840\u2013847.","journal-title":"Stroke"},{"key":"16_CR48","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1006\/exnr.2000.7367","volume":"163","author":"D Reglodi","year":"2000","unstructured":"Reglodi D, Somogyvari-Vigh A, Maderdrut JL, Vigh S, Arimura A: Postischemic spontaneous hyperthermia and its effects in middle cerebral artery occlusion in the rat. Exp Neurol 2000, 163: 399\u2013407. 10.1006\/exnr.2000.7367","journal-title":"Exp Neurol"},{"key":"16_CR49","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1007\/s00221-001-0909-4","volume":"142","author":"H Abraham","year":"2002","unstructured":"Abraham H, Somogyvari-Vigh A, Maderdrut JL, Vigh S, Arimura A: Filament size influences temperature changes and brain damage following middle cerebral artery occlusion in rats. Exp Brain Res 2002, 142: 131\u2013138. 10.1007\/s00221-001-0909-4","journal-title":"Exp Brain Res"},{"key":"16_CR50","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/0006-8993(94)91071-5","volume":"649","author":"Q Zhao","year":"1994","unstructured":"Zhao Q, Memezawa H, Smith ML, Siesjo BK: Hyperthermia complicates middle cerebral artery occlusion induced by an intraluminal filament. Brain Res 1994, 649: 253\u2013259. 10.1016\/0006-8993(94)91071-5","journal-title":"Brain Res"},{"key":"16_CR51","doi-asserted-by":"publisher","first-page":"4710","DOI":"10.1073\/pnas.081011098","volume":"98","author":"K Jin","year":"2001","unstructured":"Jin K, Minami M, Lan JQ, Mao XO, Batteur S, Simon RP, Greenberg DA: Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat. Proc Natl Acad Sci USA 2001, 98: 4710\u20134715. 10.1073\/pnas.081011098","journal-title":"Proc Natl Acad Sci USA"},{"key":"16_CR52","doi-asserted-by":"publisher","first-page":"1890","DOI":"10.1161\/01.STR.32.8.1890","volume":"32","author":"Y Yagita","year":"2001","unstructured":"Yagita Y, Kitagawa K, Ohtsuki T, Takasawa K, Miyata T, Okano H, Hori M, Matsumoto M: Neurogenesis by progenitor cells in the ischemic adult rat hippocampus. Stroke 2001, 32: 1890\u20131896.","journal-title":"Stroke"},{"key":"16_CR53","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1002\/jnr.20724","volume":"83","author":"C Ernst","year":"2006","unstructured":"Ernst C, Christie BR: Temporally specific proliferation events are induced in the hippocampus following acute focal injury. J Neurosci Res 2006, 83: 349\u2013361. 10.1002\/jnr.20724","journal-title":"J Neurosci Res"},{"key":"16_CR54","doi-asserted-by":"crossref","first-page":"7768","DOI":"10.1523\/JNEUROSCI.18-19-07768.1998","volume":"18","author":"J Liu","year":"1998","unstructured":"Liu J, Solway K, Messing RO, Sharp FR: Increased neurogenesis in the dentate gyrus after transient global ischemia in gerbils. J Neurosci 1998, 18: 7768\u20137778.","journal-title":"J Neurosci"},{"key":"16_CR55","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1097\/01.WCB.0000100065.36077.4A","volume":"24","author":"T Sasaki","year":"2004","unstructured":"Sasaki T, Kitagawa K, Yamagata K, Takemiya T, Tanaka S, Omura-Matsuoka E, Sugiura S, Matsumoto M, Hori M: Amelioration of hippocampal neuronal damage after transient forebrain ischemia in cyclooxygenase-2-deficient mice. J Cereb Blood Flow Metab 2004, 24: 107\u2013113. 10.1097\/01.WCB.0000100065.36077.4A","journal-title":"J Cereb Blood Flow Metab"},{"key":"16_CR56","doi-asserted-by":"publisher","first-page":"1043","DOI":"10.1016\/S0006-3223(00)00228-6","volume":"47","author":"TM Madsen","year":"2000","unstructured":"Madsen TM, Treschow A, Bengzon J, Bolwig TG, Lindvall O, Tingstrom A: Increased neurogenesis in a model of electroconvulsive therapy. Biol Psychiatry 2000, 47: 1043\u20131049. 10.1016\/S0006-3223(00)00228-6","journal-title":"Biol Psychiatry"},{"key":"16_CR57","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1016\/j.neuroscience.2005.06.082","volume":"135","author":"MM Kluska","year":"2005","unstructured":"Kluska MM, Witte OW, Bolz J, Redecker C: Neurogenesis in the adult dentate gyrus after cortical infarcts: effects of infarct location, N-methyl-D-aspartate receptor blockade and anti-inflammatory treatment. Neuroscience 2005, 135: 723\u2013735. 10.1016\/j.neuroscience.2005.06.082","journal-title":"Neuroscience"},{"key":"16_CR58","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1046\/j.0953-816x.2001.01611.x","volume":"14","author":"A Arvidsson","year":"2001","unstructured":"Arvidsson A, Kokaia Z, Lindvall O: N-methyl-D-aspartate receptor-mediated increase of neurogenesis in adult rat dentate gyrus following stroke. Eur J Neurosci 2001, 14: 10\u201318. 10.1046\/j.0953-816x.2001.01611.x","journal-title":"Eur J Neurosci"},{"key":"16_CR59","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1097\/00004647-200203000-00007","volume":"22","author":"K Takasawa","year":"2002","unstructured":"Takasawa K, Kitagawa K, Yagita Y, Sasaki T, Tanaka S, Matsushita K, Ohstuki T, Miyata T, Okano H, Hori M, et al.: Increased proliferation of neural progenitor cells but reduced survival of newborn cells in the contralateral hippocampus after focal cerebral ischemia in rats. J Cereb Blood Flow Metab 2002, 22: 299\u2013307. 10.1097\/00004647-200203000-00007","journal-title":"J Cereb Blood Flow Metab"},{"key":"16_CR60","doi-asserted-by":"publisher","first-page":"586","DOI":"10.1046\/j.1471-4159.2003.02022.x","volume":"87","author":"RJ Dempsey","year":"2003","unstructured":"Dempsey RJ, Sailor KA, Bowen KK, Tureyen K, Vemuganti R: Stroke-induced progenitor cell proliferation in adult spontaneously hypertensive rat brain: effect of exogenous IGF-1 and GDNF. J Neurochem 2003, 87: 586\u2013597. 10.1046\/j.1471-4159.2003.02022.x","journal-title":"J Neurochem"},{"key":"16_CR61","doi-asserted-by":"publisher","first-page":"1790","DOI":"10.1161\/01.STR.0000173151.36031.be","volume":"36","author":"V Darsalia","year":"2005","unstructured":"Darsalia V, Heldmann U, Lindvall O, Kokaia Z: Stroke-induced neurogenesis in aged brain. Stroke 2005, 36: 1790\u20131795. 10.1161\/01.STR.0000173151.36031.be","journal-title":"Stroke"},{"key":"16_CR62","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1016\/S0306-4522(00)00297-9","volume":"100","author":"M Sabbatini","year":"2000","unstructured":"Sabbatini M, Strocchi P, Vitaioli L, Amenta F: The hippocampus in spontaneously hypertensive rats: a quantitative microanatomical study. Neuroscience 2000, 100: 251\u2013258. 10.1016\/S0306-4522(00)00297-9","journal-title":"Neuroscience"},{"key":"16_CR63","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1016\/S0047-6374(01)00362-1","volume":"123","author":"M Sabbatini","year":"2002","unstructured":"Sabbatini M, Catalani A, Consoli C, Marletta N, Tomassoni D, Avola R: The hippocampus in spontaneously hypertensive rats: an animal model of vascular dementia? Mech Ageing Dev 2002, 123: 547\u2013559. 10.1016\/S0047-6374(01)00362-1","journal-title":"Mech Ageing Dev"},{"key":"16_CR64","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1002\/1096-9861(20001002)425:4<479::AID-CNE2>3.0.CO;2-3","volume":"425","author":"TD Palmer","year":"2000","unstructured":"Palmer TD, Willhoite AR, Gage FH: Vascular niche for adult hippocampal neurogenesis. J Comp Neurol 2000, 425: 479\u2013494. 10.1002\/1096-9861(20001002)425:4<479::AID-CNE2>3.0.CO;2-3","journal-title":"J Comp Neurol"}],"container-title":["Experimental &amp; Translational Stroke Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/2040-7378-2-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/2040-7378-2-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/2040-7378-2-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,22]],"date-time":"2019-01-22T06:44:38Z","timestamp":1548139478000},"score":1,"resource":{"primary":{"URL":"https:\/\/etsmjournal.biomedcentral.com\/articles\/10.1186\/2040-7378-2-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,4,6]]},"references-count":64,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["16"],"URL":"https:\/\/doi.org\/10.1186\/2040-7378-2-8","relation":{},"ISSN":["2040-7378"],"issn-type":[{"value":"2040-7378","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,4,6]]},"article-number":"8"}}