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The zebrafish model organism database (ZFIN) uses the ZFA and ZFS to annotate phenotype and gene expression data from the primary literature and from contributed data sets.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The ZFA models anatomy and development with a subclass hierarchy, a partonomy, and a developmental hierarchy and with relationships to the ZFS that define the stages during which each anatomical entity exists. The ZFA and ZFS are developed utilizing OBO Foundry principles to ensure orthogonality, accessibility, and interoperability. The ZFA has 2860 classes representing a diversity of anatomical structures from different anatomical systems and from different stages of development.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The ZFA describes zebrafish anatomy and development semantically for the purposes of annotating gene expression and anatomical phenotypes. The ontology and the data have been used by other resources to perform cross-species queries of gene expression and phenotype data, providing insights into genetic relationships, morphological evolution, and models of human disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/2041-1480-5-12","type":"journal-article","created":{"date-parts":[[2014,2,25]],"date-time":"2014-02-25T13:01:36Z","timestamp":1393333296000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":67,"title":["The zebrafish anatomy and stage ontologies: representing the anatomy and development of Danio rerio"],"prefix":"10.1186","volume":"5","author":[{"given":"Ceri E","family":"Van Slyke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yvonne M","family":"Bradford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monte","family":"Westerfield","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa A","family":"Haendel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,2,25]]},"reference":[{"key":"161_CR1","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/j.ydbio.2012.08.026","volume":"371","author":"DM Medeiros","year":"2012","unstructured":"Medeiros DM, Crump JG: New perspectives on pharyngeal dorsoventral patterning in development and evolution of the vertebrate jaw. 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