{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:12:21Z","timestamp":1787497941885,"version":"build-2736575974"},"reference-count":88,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,6,10]],"date-time":"2011-06-10T00:00:00Z","timestamp":1307664000000},"content-version":"vor","delay-in-days":160,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical &amp; Translational All"],"published-print":{"date-parts":[[2011,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    For decades, fungi have been recognized as associated with asthma and other reactive airway diseases. In contrast to type I\u2010mediated allergies caused by pollen, fungi cause a large number of allergic diseases such as allergic bronchopulmonary mycoses, rhinitis, allergic sinusitis and hypersensitivity pneumonitis. Amongst the fungi,\n                    <jats:italic>Aspergillus fumigatus<\/jats:italic>\n                    is the most prevalent cause of severe pulmonary allergic disease, including allergic bronchopulmonary aspergillosis (ABPA), known to be associated with chronic lung injury and deterioration in pulmonary function in people with chronic asthma and cystic fibrosis (CF). The goal of this review is to discuss new understandings of host\u2010pathogen interactions in the genesis of allergic airway diseases caused by\n                    <jats:italic>A. fumigatus<\/jats:italic>\n                    . Host and pathogen related factors that participate in triggering the inflammatory cycle leading to pulmonary exacerbations in ABPA are discussed.\n                  <\/jats:p>","DOI":"10.1186\/2045-7022-1-4","type":"journal-article","created":{"date-parts":[[2011,6,11]],"date-time":"2011-06-11T02:20:39Z","timestamp":1307758839000},"source":"Crossref","is-referenced-by-count":79,"title":["Impact of\n                    <i>Aspergillus fumigatus<\/i>\n                    in allergic airway diseases"],"prefix":"10.1002","volume":"1","author":[{"given":"Neelkamal","family":"Chaudhary","sequence":"first","affiliation":[{"name":"School of Medicine Johns Hopkins University Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kieren A","family":"Marr","sequence":"additional","affiliation":[{"name":"School of Medicine Johns Hopkins University Baltimore MD USA"},{"name":"The Sidney Kimmel Cancer Center Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,6,10]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000107578"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.06.00074705"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2009.03339.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/13693786.2010.504752"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2009.10.011"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/ACI.0b013e32833653d7"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/mi.2009.102"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00014-09"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.7.4.317"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.118.1.66"},{"key":"e_1_2_7_12_1","first-page":"137","article-title":"Allergic bronchopulmonary aspergillosis: serologic update for 1995","volume":"46","author":"Krasnick J","year":"1995","journal-title":"J Clin Lab Immunol"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.2008.01680.x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201001-0087OC"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2010.02542.x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1569-1993(02)00033-4"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-2586"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1086\/376525"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0954-6111(95)90198-1"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1985.tb02311.x"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.2007.01432.x"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(99)70023-0"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-86-4-405"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2007.05.004"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature08264"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.63.9.3266-3271.1995"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11882-003-0021-x"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1080\/13693780802609604"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1586\/eri.10.72"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2010.05.046"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1042\/BST0370863"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.51.7.507"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2009.11.010"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.3109\/13693786.2010.529304"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.3109\/13693780903127506"},{"key":"e_1_2_7_36_1","first-page":"1035","article-title":"Aspergillus\/allergic bronchopulmonary aspergillosis in an Irish cystic fibrosis population: a diagnostically challenging entity","volume":"53","author":"Chotirmall SH","year":"2008","journal-title":"Respir Care"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200603-423OC"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.155.6.9196093"},{"key":"e_1_2_7_39_1","first-page":"45","article-title":"Cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations in allergic bronchopulmonary aspergillosis","volume":"59","author":"Miller PW","year":"1996","journal-title":"Am J Hum Genet"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2009.12.465"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200003163421102"},{"key":"e_1_2_7_42_1","first-page":"CD001108","article-title":"Azoles for allergic bronchopulmonary aspergillosis associated with asthma","author":"Wark PA","year":"2004","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.20656"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2249.2000.01232.x"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1011080229374"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.177.8.5186"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1002\/jgm.1119"},{"key":"e_1_2_7_48_1","article-title":"Lack of Cftr in CD3+ Lymphocytes Leads to Aberrant Cytokine Secretion and Hyper\u2010inflammatory Adaptive Immune Responses","author":"Mueller C","year":"2010","journal-title":"Am J Respir Cell Mol Biol"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI42388"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.169.10.5904"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.180.9.6000"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2007.04.025"},{"key":"e_1_2_7_53_1","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2000.106210"},{"key":"e_1_2_7_54_1","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1999.1093"},{"key":"e_1_2_7_55_1","doi-asserted-by":"publisher","DOI":"10.1086\/517272"},{"key":"e_1_2_7_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2004.07.060"},{"key":"e_1_2_7_57_1","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2001.119025"},{"key":"e_1_2_7_58_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.169.9.5315"},{"key":"e_1_2_7_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/mi.2007.13"},{"key":"e_1_2_7_60_1","doi-asserted-by":"publisher","DOI":"10.1038\/mi.2010.4"},{"key":"e_1_2_7_61_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI200420509"},{"key":"e_1_2_7_62_1","doi-asserted-by":"publisher","DOI":"10.1080\/mmy.39.1.9.17"},{"key":"e_1_2_7_63_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00927-07"},{"key":"e_1_2_7_64_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.176.6.3717"},{"key":"e_1_2_7_65_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.0010030"},{"key":"e_1_2_7_66_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni1460"},{"key":"e_1_2_7_67_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.200838950"},{"key":"e_1_2_7_68_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10875-009-9319-3"},{"key":"e_1_2_7_69_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-04-279307"},{"key":"e_1_2_7_70_1","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2008-0408OC"},{"key":"e_1_2_7_71_1","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/6.6.627"},{"key":"e_1_2_7_72_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature05746"},{"key":"e_1_2_7_73_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1095336"},{"key":"e_1_2_7_74_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2008.03092.x"},{"key":"e_1_2_7_75_1","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2000.109913"},{"key":"e_1_2_7_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2007.04.037"},{"key":"e_1_2_7_77_1","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.4049\/jimmunol.163.3.1205","article-title":"Peptide dose, affinity, and time of differentiation can contribute to the Th1\/Th2 cytokine balance","volume":"163","author":"Rogers PR","year":"1999","journal-title":"J Immunol"},{"key":"e_1_2_7_78_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.128.3.1611"},{"key":"e_1_2_7_79_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.2006.03007.x"},{"key":"e_1_2_7_80_1","doi-asserted-by":"publisher","DOI":"10.1515\/CCLM.2007.033"},{"key":"e_1_2_7_81_1","doi-asserted-by":"publisher","DOI":"10.2174\/187221307782418874"},{"key":"e_1_2_7_82_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1744-313X.2006.00616.x"},{"key":"e_1_2_7_83_1","doi-asserted-by":"publisher","DOI":"10.1186\/1476-7961-4-3"},{"key":"e_1_2_7_84_1","doi-asserted-by":"publisher","DOI":"10.1086\/429964"},{"key":"e_1_2_7_85_1","doi-asserted-by":"publisher","DOI":"10.1097\/ACI.0b013e3283306533"},{"key":"e_1_2_7_86_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200506-890OC"},{"key":"e_1_2_7_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2008.04.030"},{"key":"e_1_2_7_88_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-0321"},{"key":"e_1_2_7_89_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201003-0322OC"}],"container-title":["Clinical and Translational Allergy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1186\/2045-7022-1-4","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/2045-7022-1-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1186\/2045-7022-1-4","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/2045-7022-1-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1186\/2045-7022-1-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T07:11:44Z","timestamp":1693638704000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1186\/2045-7022-1-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1]]},"references-count":88,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,1]]}},"alternative-id":["10.1186\/2045-7022-1-4"],"URL":"https:\/\/doi.org\/10.1186\/2045-7022-1-4","archive":["Portico"],"relation":{},"ISSN":["2045-7022","2045-7022"],"issn-type":[{"value":"2045-7022","type":"print"},{"value":"2045-7022","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,1]]},"article-number":"4"}}