{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T17:15:07Z","timestamp":1791220507035,"version":"4.1.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Chiropr Man Therap"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Transient synovitis of the hip (TS) is considered to be a self-limiting disease in childhood. However, because the etiology is unclear and some cases precede Legg-Perthes\u2019 disease, data on follow-up are important. Our aim was to summarize the knowledge on the clinical course of TS in children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study design was a systematic review and a literature search was conducted in Medline and Embase. Studies describing short and\/or long-term follow-up of TS in children were included. Case reports, reviews and studies describing traumatic hip pain were excluded. Study quality was scored and data extraction was performed. The main outcome measures were short-term and long-term clinical course, and recurrence of symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 25 studies were included of which 14 were of high quality. At two-week follow-up, almost all children with TS were symptom free. Those with symptoms persisting for over one month were more prone to develop other hip pathology, such as Legg-Perthes\u2019 disease. The recurrence rate of TS ranged from 0\u201326.3%. At long-term follow-up, 0-10% of the children diagnosed with TS developed Legg-Perthes\u2019 disease. Hip pain after intensive physical effort and limited range of motion of the hip at long-term follow-up was reported in 12-28% and in 0-18% of the children, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The majority of the studies indicate that children with TS recover within two weeks; recurrence was seen in 0-26% of the cases. Children with TS should be followed at least six months to increase the likelihood of not missing Legg-Perthes\u2019 disease.<\/jats:p><\/jats:sec>","DOI":"10.1186\/2045-709x-21-39","type":"journal-article","created":{"date-parts":[[2013,11,14]],"date-time":"2013-11-14T10:02:14Z","timestamp":1384423334000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["What is the clinical course of transient synovitis in children: a systematic review of the literature"],"prefix":"10.1186","volume":"21","author":[{"given":"Sylvana S","family":"Asche","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rogier M","family":"van Rijn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes HJM","family":"Bessems","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marjolein","family":"Krul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sita MA","family":"Bierma-Zeinstra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,11,14]]},"reference":[{"issue":"2","key":"104_CR1","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1302\/0301-620X.69B2.3818754","volume":"69","author":"LA Landin","year":"1987","unstructured":"Landin LA, Danielsson LG, Wattsgard C: Transient synovitis of the hip. 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