{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T00:06:22Z","timestamp":1768521982011,"version":"3.49.0"},"reference-count":73,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Fluids Barriers CNS"],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1186\/2045-8118-11-2","type":"journal-article","created":{"date-parts":[[2014,1,29]],"date-time":"2014-01-29T04:01:55Z","timestamp":1390968115000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Gene expression-based comparison of the human secretory neuroepithelia of the brain choroid plexus and the ocular ciliary body: potential implications for glaucoma"],"prefix":"10.1186","volume":"11","author":[{"given":"Sarah F","family":"Janssen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theo GMF","family":"Gorgels","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacoline B","family":"ten Brink","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nomdo M","family":"Jansonius","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arthur AB","family":"Bergen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,1,29]]},"reference":[{"key":"87_CR1","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1038\/35067582","volume":"2","author":"A Alvarez-Buylla","year":"2001","unstructured":"Alvarez-Buylla A, Garcia-Verdugo JM, Tramontin AD: A unified hypothesis on the lineage of neural stem cells. Nat Rev Neurosci. 2001, 2: 287-293. 10.1038\/35067582.","journal-title":"Nat Rev Neurosci"},{"key":"87_CR2","doi-asserted-by":"publisher","first-page":"2102","DOI":"10.1016\/j.biochi.2011.06.032","volume":"93","author":"C Leclerc","year":"2011","unstructured":"Leclerc C, Neant I, Moreau M: Early neural development in vertebrates is also a matter of calcium. Biochimie. 2011, 93: 2102-2111. 10.1016\/j.biochi.2011.06.032.","journal-title":"Biochimie"},{"key":"87_CR3","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.2741\/218","volume":"3","author":"M Preston","year":"2011","unstructured":"Preston M, Sherman LS: Neural stem cell niches: roles for the hyaluronan-based extracellular matrix. Front Biosci (Schol Ed). 2011, 3: 1165-1179.","journal-title":"Front Biosci (Schol Ed)"},{"key":"87_CR4","doi-asserted-by":"publisher","first-page":"1055","DOI":"10.1242\/dev.090860","volume":"140","author":"PA Johansson","year":"2013","unstructured":"Johansson PA, Irmler M, Acampora D, Beckers J, Simeone A, Gotz M: The transcription factor Otx2 regulates choroid plexus development and function. Development. 2013, 140: 1055-1066. 10.1242\/dev.090860.","journal-title":"Development"},{"key":"87_CR5","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1016\/j.ijdevneu.2009.04.004","volume":"27","author":"KB Larsen","year":"2009","unstructured":"Larsen KB, Lutterodt M, Rath MF, Moller M: Expression of the homeobox genes PAX6, OTX2, and OTX1 in the early human fetal retina. Int J Dev Neurosci. 2009, 27: 485-492. 10.1016\/j.ijdevneu.2009.04.004.","journal-title":"Int J Dev Neurosci"},{"key":"87_CR6","doi-asserted-by":"crossref","first-page":"6853","DOI":"10.1523\/JNEUROSCI.16-21-06853.1996","volume":"16","author":"K Nicholson-Flynn","year":"1996","unstructured":"Nicholson-Flynn K, Hitchcock-DeGregori SE, Levitt P: Restricted expression of the actin-regulatory protein, tropomyosin, defines distinct boundaries, evaginating neuroepithelium, and choroid plexus forerunners during early CNS development. J Neurosci. 1996, 16: 6853-6863.","journal-title":"J Neurosci"},{"key":"87_CR7","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1016\/j.ydbio.2006.04.461","volume":"296","author":"FJ VON","year":"2006","unstructured":"Von FJ, Wizenmann A, Gotz M: The transcription factors Emx1 and Emx2 suppress choroid plexus development and promote neuroepithelial cell fate. Dev Biol. 2006, 296: 239-252. 10.1016\/j.ydbio.2006.04.461.","journal-title":"Dev Biol"},{"key":"87_CR8","doi-asserted-by":"publisher","first-page":"15934","DOI":"10.1523\/JNEUROSCI.3227-12.2012","volume":"32","author":"M Watanabe","year":"2012","unstructured":"Watanabe M, Kang YJ, Davies LM, Meghpara S, Lau K, Chung CY, Kathiriya J, Hadjantonakis AK, Monuki ES: BMP4 sufficiency to induce choroid plexus epithelial fate from embryonic stem cell-derived neuroepithelial progenitors. J Neurosci. 2012, 32: 15934-15945. 10.1523\/JNEUROSCI.3227-12.2012.","journal-title":"J Neurosci"},{"key":"87_CR9","doi-asserted-by":"crossref","first-page":"4435","DOI":"10.1242\/dev.129.19.4435","volume":"129","author":"S Zhao","year":"2002","unstructured":"Zhao S, Chen Q, Hung FC, Overbeek PA: BMP signaling is required for development of the ciliary body. Development. 2002, 129: 4435-4442.","journal-title":"Development"},{"key":"87_CR10","first-page":"2274","volume":"19","author":"SS Whitmore","year":"2013","unstructured":"Whitmore SS, Braun TA, Skeie JM, Haas CM, Sohn EH, Stone EM, Scheetz TE, Mullins RF: Altered gene expression in dry age-related macular degeneration suggests early loss of choroidal endothelial cells. Mol Vis. 2013, 19: 2274-2297.","journal-title":"Mol Vis"},{"key":"87_CR11","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.exer.2013.03.004","volume":"111","author":"AH Wagner","year":"2013","unstructured":"Wagner AH, Anand VN, Wang WH, Chatterton JE, Sun D, Shepard AR, Jacobson N, Pang IH, Deluca AP, Casavany TL, Scheetz TE, Mullins RF, Braun TA, Clark AF: Exon-level expression profiling of ocular tissues. Exp Eye Res. 2013, 111: 105-111.","journal-title":"Exp Eye Res"},{"key":"87_CR12","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1097\/01.pas.0000176430.88702.e0","volume":"30","author":"M Hasselblatt","year":"2006","unstructured":"Hasselblatt M, B\u00f6hm C, Tatenhorst L, Dinh V, Newrzella D, Keyvani K, Jeibmann A, Buerger H, Rickert CH, Paulus W: Identification of novel diagnostic markers for choroid plexus tumors: a microarray-based approach. Am J Surg Pathol. 2006, 30: 66-74. 10.1097\/01.pas.0000176430.88702.e0.","journal-title":"Am J Surg Pathol"},{"key":"87_CR13","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1186\/1471-2164-10-164","volume":"10","author":"JC Booij","year":"2009","unstructured":"Booij JC, Van SS, Swagemakers SM, Essing AH, Verkerk AJ, Van Der Spek PJ, Gorgels TG, Bergen AA: Functional annotation of the human retinal pigment epithelium transcriptome. BMC Genomics. 2009, 10: 164-10.1186\/1471-2164-10-164.","journal-title":"BMC Genomics"},{"key":"87_CR14","doi-asserted-by":"publisher","first-page":"e9341","DOI":"10.1371\/journal.pone.0009341","volume":"5","author":"JC Booij","year":"2010","unstructured":"Booij JC, Ten Brink JB, Swagemakers SM, Verkerk AJ, Essing AH, van der Spek PJ, Bergen AA: A new strategy to identify and annotate human RPE-specific gene expression. PLoS One. 2010, 5: e9341-10.1371\/journal.pone.0009341.","journal-title":"PLoS One"},{"key":"87_CR15","first-page":"1608","volume":"13","author":"SS van Soest","year":"2007","unstructured":"van Soest SS, de Wit GM, Essing AH, Ten Brink JB, Kamphuis W, De Jong PT, Bergen AA: Comparison of human retinal pigment epithelium gene expression in macula and periphery highlights potential topographic differences in Bruch's membrane. Mol Vis. 2007, 13: 1608-1617.","journal-title":"Mol Vis"},{"key":"87_CR16","doi-asserted-by":"publisher","first-page":"e44973","DOI":"10.1371\/journal.pone.0044973","volume":"7","author":"SF Janssen","year":"2012","unstructured":"Janssen SF, Gorgels TG, Bossers K, Ten Brink JB, Essing AH, Nagtegaal M, van der Spek PJ, Jansonius NM, Bergen AA: Gene expression and functional annotation of the human ciliary body epithelia. PLoS One. 2012, 7: e44973-10.1371\/journal.pone.0044973.","journal-title":"PLoS One"},{"issue":"12","key":"87_CR17","doi-asserted-by":"publisher","first-page":"e83345","DOI":"10.1371\/journal.pone.0083345","volume":"8","author":"SF Janssen","year":"2013","unstructured":"Janssen SF, van der Spek SJF, Ten Brink JB, Essing AHW, Gorgels TGMF, van der Spek PJ, Jansonius NM, Bergen AAB: Gene expression and functional annotation of the human and mouse choroid plexus epithelium. PlosOne. 2013, 8 (12): e83345-10.1371\/journal.pone.0083345.","journal-title":"PlosOne"},{"key":"87_CR18","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1093\/jnen\/59.7.561","volume":"59","author":"N Strazielle","year":"2000","unstructured":"Strazielle N, Ghersi-Egea JF: Choroid plexus in the central nervous system: biology and physiopathology. J Neuropathol Exp Neurol. 2000, 59: 561-574.","journal-title":"J Neuropathol Exp Neurol"},{"key":"87_CR19","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1016\/j.preteyeres.2007.01.002","volume":"26","author":"M Coca-Prados","year":"2007","unstructured":"Coca-Prados M, Escribano J: New perspectives in aqueous humor secretion and in glaucoma: the ciliary body as a multifunctional neuroendocrine gland. Prog Retin Eye Res. 2007, 26: 239-262. 10.1016\/j.preteyeres.2007.01.002.","journal-title":"Prog Retin Eye Res"},{"key":"87_CR20","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1016\/j.exer.2003.09.021","volume":"78","author":"MM Civan","year":"2004","unstructured":"Civan MM, Macknight AD: The ins and outs of aqueous humour secretion. Exp Eye Res. 2004, 78: 625-631. 10.1016\/j.exer.2003.09.021.","journal-title":"Exp Eye Res"},{"key":"87_CR21","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1186\/1743-8454-5-10","volume":"5","author":"CE Johanson","year":"2008","unstructured":"Johanson CE, Duncan JA, Klinge PM, Brinker T, Stopa EG, Silverberg GD: Multiplicity of cerebrospinal fluid functions: New challenges in health and disease. Cerebrospinal Fluid Res. 2008, 5: 10-10.1186\/1743-8454-5-10.","journal-title":"Cerebrospinal Fluid Res"},{"key":"87_CR22","doi-asserted-by":"publisher","first-page":"5189","DOI":"10.1167\/iovs.03-0174","volume":"44","author":"JB Jonas","year":"2003","unstructured":"Jonas JB, Berenshtein E, Holbach L: Anatomic relationship between lamina cribrosa, intraocular space, and cerebrospinal fluid space. Invest Ophthalmol Vis Sci. 2003, 44: 5189-5195. 10.1167\/iovs.03-0174.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"87_CR23","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1097\/IJG.0b013e31815c5f7c","volume":"17","author":"WH Morgan","year":"2008","unstructured":"Morgan WH, Yu DY, Balaratnasingam C: The role of cerebrospinal fluid pressure in glaucoma pathophysiology: the dark side of the optic disc. J Glaucoma. 2008, 17: 408-413. 10.1097\/IJG.0b013e31815c5f7c.","journal-title":"J Glaucoma"},{"key":"87_CR24","first-page":"1163","volume":"36","author":"WH Morgan","year":"1995","unstructured":"Morgan WH, Yu DY, Cooper RL, Alder VA, Cringle SJ, Constable IJ: The influence of cerebrospinal fluid pressure on the lamina cribrosa tissue pressure gradient. Invest Ophthalmol Vis Sci. 1995, 36: 1163-1172.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"87_CR25","doi-asserted-by":"publisher","first-page":"5412","DOI":"10.1167\/iovs.08-2228","volume":"49","author":"JP Berdahl","year":"2008","unstructured":"Berdahl JP, Fautsch MP, Stinnett SS, Allingham RR: Intracranial pressure in primary open angle glaucoma, normal tension glaucoma, and ocular hypertension: a case\u2013control study. Invest Ophthalmol Vis Sci. 2008, 49: 5412-5418. 10.1167\/iovs.08-2228.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"87_CR26","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1016\/j.ophtha.2008.01.013","volume":"115","author":"JP Berdahl","year":"2008","unstructured":"Berdahl JP, Allingham RR, Johnson DH: Cerebrospinal fluid pressure is decreased in primary open-angle glaucoma. Ophthalmology. 2008, 115: 763-768. 10.1016\/j.ophtha.2008.01.013.","journal-title":"Ophthalmology"},{"key":"87_CR27","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/j.ophtha.2009.06.058","volume":"117","author":"R Ren","year":"2010","unstructured":"Ren R, Jonas JB, Tian G, Zhen Y, Ma K, Li S, Wang H, Li B, Zhang X, Wang N: Cerebrospinal fluid pressure in glaucoma: a prospective study. Ophthalmology. 2010, 117: 259-266. 10.1016\/j.ophtha.2009.06.058.","journal-title":"Ophthalmology"},{"key":"87_CR28","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1007\/s00417-011-1657-1","volume":"249","author":"R Ren","year":"2011","unstructured":"Ren R, Wang N, Zhang X, Cui T, Jonas JB: Trans-lamina cribrosa pressure difference correlated with neuroretinal rim area in glaucoma. Graefes Arch Clin Exp Ophthalmol. 2011, 249: 1057-1063. 10.1007\/s00417-011-1657-1.","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"87_CR29","doi-asserted-by":"publisher","first-page":"2065","DOI":"10.1016\/j.ophtha.2012.03.054","volume":"119","author":"N Wang","year":"2012","unstructured":"Wang N, Xie X, Yang D, Xian J, Li Y, Ren R, Peng X, Jonas JB, Weinreb RN: Orbital cerebrospinal fluid space in glaucoma: the Beijing intracranial and intraocular pressure (iCOP) study. Ophthalmology. 2012, 119: 2065-2073. 10.1016\/j.ophtha.2012.03.054.","journal-title":"Ophthalmology"},{"key":"87_CR30","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1016\/j.neuroscience.2004.07.003","volume":"129","author":"PD Brown","year":"2004","unstructured":"Brown PD, Davies SL, Speake T, Millar ID: Molecular mechanisms of cerebrospinal fluid production. Neuroscience. 2004, 129: 957-970.","journal-title":"Neuroscience"},{"key":"87_CR31","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.preteyeres.2013.09.001","volume":"37","author":"SF Janssen","year":"2013","unstructured":"Janssen SF, Gorgels TG, Ramdas WD, Klaver CC, van Duijn CM, Jansonius NM, Bergen AA: The vast complexity of primary open angle glaucoma: Disease genes, risks, molecular mechanisms and pathobiology. Prog Retin Eye Res. 2013, 37: 31-67.","journal-title":"Prog Retin Eye Res"},{"key":"87_CR32","doi-asserted-by":"publisher","first-page":"5329","DOI":"10.1242\/dev.02153","volume":"132","author":"B Banizs","year":"2005","unstructured":"Banizs B, Pike MM, Millican CL, Ferguson WB, Komlosi P, Sheetz J, Bell PD, Schwiebert EM, Yoder BK: Dysfunctional cilia lead to altered ependyma and choroid plexus function, and result in the formation of hydrocephalus. Development. 2005, 132: 5329-5339. 10.1242\/dev.02153.","journal-title":"Development"},{"key":"87_CR33","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1111\/j.1600-0854.2009.01016.x","volume":"11","author":"K Narita","year":"2010","unstructured":"Narita K, Kawate T, Kakinuma N, Takeda S: Multiple primary cilia modulate the fluid transcytosis in choroid plexus epithelium. Traffic. 2010, 11: 287-301. 10.1111\/j.1600-0854.2009.01016.x.","journal-title":"Traffic"},{"key":"87_CR34","first-page":"503","volume":"62","author":"S Dhechakaisaya","year":"1979","unstructured":"Dhechakaisaya S, Shuangshoti S, Susakares A: Extramedullary hematopoiesis of cranial dura mater and choroid plexus and terminal convulsions in a patient with thalassemia-hemoglobin E disease. J Med Assoc Thai. 1979, 62: 503-511.","journal-title":"J Med Assoc Thai"},{"key":"87_CR35","doi-asserted-by":"publisher","first-page":"1715","DOI":"10.1111\/j.1537-2995.2011.03499.x","volume":"52","author":"AE Eskazan","year":"2012","unstructured":"Eskazan AE, Ar MC, Baslar Z: Intracranial extramedullary hematopoiesis in patients with thalassemia: a case report and review of the literature. Transfusion. 2012, 52: 1715-1720. 10.1111\/j.1537-2995.2011.03499.x.","journal-title":"Transfusion"},{"key":"87_CR36","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1186\/1752-1947-5-580","volume":"5","author":"H Tabesh","year":"2011","unstructured":"Tabesh H, Shekarchizadeh A, Mahzouni P, Mokhtari M, Abrishamkar S, Abbasi FS: An intracranial extramedullary hematopoiesis in a 34-year-old man with beta thalassemia: a case report. J Med Case Rep. 2011, 5: 580-10.1186\/1752-1947-5-580.","journal-title":"J Med Case Rep"},{"key":"87_CR37","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1006\/bbrc.2000.2473","volume":"270","author":"I Ahmad","year":"2000","unstructured":"Ahmad I, Tang L, Pham H: Identification of neural progenitors in the adult mammalian eye. Biochem Biophys Res Commun. 2000, 270: 517-521. 10.1006\/bbrc.2000.2473.","journal-title":"Biochem Biophys Res Commun"},{"key":"87_CR38","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1016\/j.exer.2009.04.005","volume":"89","author":"B Bhatia","year":"2009","unstructured":"Bhatia B, Singhal S, Lawrence JM, Khaw PT, Limb GA: Distribution of Muller stem cells within the neural retina: evidence for the existence of a ciliary margin-like zone in the adult human eye. Exp Eye Res. 2009, 89: 373-382. 10.1016\/j.exer.2009.04.005.","journal-title":"Exp Eye Res"},{"key":"87_CR39","doi-asserted-by":"publisher","first-page":"1653","DOI":"10.1016\/j.visres.2004.12.017","volume":"45","author":"AV Das","year":"2005","unstructured":"Das AV, James J, Rahnenfuhrer J, Thoreson WB, Bhattacharya S, Zhao X, Ahmad I: Retinal properties and potential of the adult mammalian ciliary epithelium stem cells. Vision Res. 2005, 45: 1653-1666. 10.1016\/j.visres.2004.12.017.","journal-title":"Vision Res"},{"key":"87_CR40","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1159\/000048710","volume":"23","author":"AJ Fischer","year":"2001","unstructured":"Fischer AJ, Reh TA: Transdifferentiation of pigmented epithelial cells: a source of retinal stem cells?. Dev Neurosci. 2001, 23: 268-276. 10.1159\/000048710.","journal-title":"Dev Neurosci"},{"key":"87_CR41","doi-asserted-by":"publisher","first-page":"992","DOI":"10.1016\/j.modgep.2006.04.003","volume":"6","author":"J Lord-Grignon","year":"2006","unstructured":"Lord-Grignon J, Abdouh M, Bernier G: Identification of genes expressed in retinal progenitor\/stem cell colonies isolated from the ocular ciliary body of adult mice. Gene Expr Patterns. 2006, 6: 992-999. 10.1016\/j.modgep.2006.04.003.","journal-title":"Gene Expr Patterns"},{"key":"87_CR42","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1002\/cne.21860","volume":"511","author":"GC Martinez-Navarrete","year":"2008","unstructured":"Martinez-Navarrete GC, Angulo A, Martin-Nieto J, Cuenca N: Gradual morphogenesis of retinal neurons in the peripheral retinal margin of adult monkeys and humans. J Comp Neurol. 2008, 511: 557-580. 10.1002\/cne.21860.","journal-title":"J Comp Neurol"},{"key":"87_CR43","doi-asserted-by":"publisher","first-page":"93","DOI":"10.2174\/1567202611310020002","volume":"10","author":"C Abburi","year":"2013","unstructured":"Abburi C, Prabhakar S, Kalra J, Huria A, Anand A: Vascular endothelial growth factor (VEGF) induced proliferation of human fetal derived ciliary epithelium stem cells is mediated by jagged-N cadherin pathway. Curr Neurovasc Res. 2013, 10: 93-102. 10.2174\/1567202611310020002.","journal-title":"Curr Neurovasc Res"},{"key":"87_CR44","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1242\/bio.2012027","volume":"1","author":"BG Ballios","year":"2012","unstructured":"Ballios BG, Clarke L, Coles BL, Shoichet MS, van der Kooy D: The adult retinal stem cell is a rare cell in the ciliary epithelium whose progeny can differentiate into photoreceptors. Biol Open. 2012, 1: 237-246. 10.1242\/bio.2012027.","journal-title":"Biol Open"},{"key":"87_CR45","doi-asserted-by":"publisher","first-page":"e33338","DOI":"10.1371\/journal.pone.0033338","volume":"7","author":"GC Demontis","year":"2012","unstructured":"Demontis GC, Aruta C, Comitato A, De MA, Marigo V: Functional and molecular characterization of rod-like cells from retinal stem cells derived from the adult ciliary epithelium. PLoS One. 2012, 7: e33338-10.1371\/journal.pone.0033338.","journal-title":"PLoS One"},{"key":"87_CR46","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1002\/stem.1283","volume":"31","author":"Y Fang","year":"2013","unstructured":"Fang Y, Cho KS, Tchedre K, Lee SW, Guo C, Kinouchi H, Fried S, Sun X, Chen DF: Ephrin-A3 suppresses Wnt signaling to control retinal stem cell potency. Stem Cells. 2013, 31: 349-359. 10.1002\/stem.1283.","journal-title":"Stem Cells"},{"key":"87_CR47","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1002\/stem.279","volume":"28","author":"T Inoue","year":"2010","unstructured":"Inoue T, Coles BL, Dorval K, Bremner R, Bessho Y, Kageyama R, Hino S, Matsuoka M, Craft CM, McInnes RR: Maximizing functional photoreceptor differentiation from adult human retinal stem cells. Stem Cells. 2010, 28: 489-500.","journal-title":"Stem Cells"},{"key":"87_CR48","doi-asserted-by":"publisher","first-page":"2430","DOI":"10.1634\/stemcells.2007-0035","volume":"25","author":"A MacNeil","year":"2007","unstructured":"MacNeil A, Pearson RA, MacLaren RE, Smith AJ, Sowden JC, Ali RR: Comparative analysis of progenitor cells isolated from the iris, pars plana, and ciliary body of the adult porcine eye. Stem Cells. 2007, 25: 2430-2438. 10.1634\/stemcells.2007-0035.","journal-title":"Stem Cells"},{"key":"87_CR49","doi-asserted-by":"publisher","first-page":"2032","DOI":"10.1126\/science.287.5460.2032","volume":"287","author":"V Tropepe","year":"2000","unstructured":"Tropepe V, Coles BL, Chiasson BJ, Horsford DJ, Elia AJ, McInnes RR, van der Kooy D: Retinal stem cells in the adult mammalian eye. Science. 2000, 287: 2032-2036. 10.1126\/science.287.5460.2032.","journal-title":"Science"},{"key":"87_CR50","doi-asserted-by":"publisher","first-page":"1674","DOI":"10.1167\/iovs.06-1034","volume":"48","author":"H Xu","year":"2007","unstructured":"Xu H, Sta Iglesia DD, Kielczewski JL, Valenta DF, Pease ME, Zack DJ, Quigley HA: Characteristics of progenitor cells derived from adult ciliary body in mouse, rat, and human eyes. Invest Ophthalmol Vis Sci. 2007, 48: 1674-1682. 10.1167\/iovs.06-1034.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"87_CR51","doi-asserted-by":"publisher","first-page":"6685","DOI":"10.1073\/pnas.0901596106","volume":"106","author":"SA Cicero","year":"2009","unstructured":"Cicero SA, Johnson D, Reyntjens S, Frase S, Connell S, Chow LM, Baker SJ, Sorrentino BP, Dyer MA: Cells previously identified as retinal stem cells are pigmented ciliary epithelial cells. Proc Natl Acad Sci USA. 2009, 106: 6685-6690. 10.1073\/pnas.0901596106.","journal-title":"Proc Natl Acad Sci USA"},{"key":"87_CR52","doi-asserted-by":"publisher","first-page":"1048","DOI":"10.1002\/stem.423","volume":"28","author":"S Gualdoni","year":"2010","unstructured":"Gualdoni S, Baron M, Lakowski J, Decembrini S, Smith AJ, Pearson RA, Ali RR, Sowden JC: Adult ciliary epithelial cells, previously identified as retinal stem cells with potential for retinal repair, fail to differentiate into new rod photoreceptors. Stem Cells. 2010, 28: 1048-1059. 10.1002\/stem.423.","journal-title":"Stem Cells"},{"key":"87_CR53","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1159\/000092359","volume":"42","author":"P Longatti","year":"2006","unstructured":"Longatti P, Basaldella L, Orvieto E: Dei Tos A, Martinuzzi A: Aquaporin(s) expression in choroid plexus tumours. Pediatr Neurosurg. 2006, 42: 228-233. 10.1159\/000092359.","journal-title":"Pediatr Neurosurg"},{"key":"87_CR54","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1016\/j.preteyeres.2008.04.001","volume":"27","author":"AS Verkman","year":"2008","unstructured":"Verkman AS, Ruiz-Ederra J, Levin MH: Functions of aquaporins in the eye. Prog Retin Eye Res. 2008, 27: 420-433. 10.1016\/j.preteyeres.2008.04.001.","journal-title":"Prog Retin Eye Res"},{"key":"87_CR55","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1016\/j.neuroscience.2003.10.004","volume":"123","author":"MF Karadsheh","year":"2004","unstructured":"Karadsheh MF, Byun N, Mount DB, Delpire E: Localization of the KCC4 potassium-chloride cotransporter in the nervous system. Neuroscience. 2004, 123: 381-391. 10.1016\/j.neuroscience.2003.10.004.","journal-title":"Neuroscience"},{"key":"87_CR56","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1186\/2043-9113-3-21","volume":"3","author":"SF Janssen","year":"2013","unstructured":"Janssen SF, Gorgels TGMF, van der Spek PJ, Jansonius NM, Bergen AAB: In silico analysis of the molecular machinery underlying aquoeus humor production: potential implication for glaucoma. J CLin Bioinform. 2013, 3: 21-10.1186\/2043-9113-3-21.","journal-title":"J CLin Bioinform"},{"key":"87_CR57","doi-asserted-by":"crossref","first-page":"C173","DOI":"10.1152\/ajpcell.1997.272.1.C173","volume":"272","author":"MD Plotkin","year":"1997","unstructured":"Plotkin MD, Kaplan MR, Peterson LN: Gullans SRm Hebert SC, Delpire E: Expression of the Na(+)-K(+)-2Cl- cotransporter BSC2 in the nervous system. Am J Physiol. 1997, 272: C173-SC183.","journal-title":"Am J Physiol"},{"key":"87_CR58","doi-asserted-by":"crossref","first-page":"C1565","DOI":"10.1152\/ajpcell.1998.275.6.C1565","volume":"275","author":"Q Wu","year":"1998","unstructured":"Wu Q, Delpire E, Hebert SC, Strange K: Functional demonstration of Na\u2009+\u2009\u2212K\u2009+\u2009\u22122Cl- cotransporter activity in isolated, polarized choroid plexus cells. Am J Physiol. 1998, 275: C1565-C1572.","journal-title":"Am J Physiol"},{"key":"87_CR59","first-page":"304","volume":"4","author":"HL Christensen","year":"2013","unstructured":"Christensen HL, Nguyen AT, Pedersen FD, Damkier HH: Na\u2009+\u2009dependent acid\u2013base transporters in the choroid plexus; insights from slc4 and slc9 gene deletion studies. Front Physion. 2013, 4: 304-","journal-title":"Front Physion"},{"key":"87_CR60","doi-asserted-by":"crossref","first-page":"F920","DOI":"10.1152\/ajprenal.2001.281.5.F920","volume":"281","author":"D Bok","year":"2001","unstructured":"Bok D, Schibler MJ, Pushkin A, Sassani P, Abuladze N, Naser Z, Kurtz I: Immunolocalization of electrogenic sodium-bicarbonate cotransporters pNBC1 and kNBC1 in the rat eye. Am J Physiol Renal Physiol. 2001, 281: F920-F935.","journal-title":"Am J Physiol Renal Physiol"},{"key":"87_CR61","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1007\/BF00370788","volume":"419","author":"MA Watsky","year":"1991","unstructured":"Watsky MA, Cooper K, Rae JL: Sodium channels in ocular epithelia. Pflugers Arch. 1991, 419: 454-459. 10.1007\/BF00370788.","journal-title":"Pflugers Arch"},{"key":"87_CR62","doi-asserted-by":"publisher","first-page":"1539","DOI":"10.1016\/j.ophtha.2012.02.004","volume":"119","author":"KP Burdon","year":"2012","unstructured":"Burdon KP, Crawford A, Casson RJ, Hewitt AW, Landers J, Danoy P, Mackey DA, Mitchell P, Healey PR, Craig JE: Glaucoma risk alleles at CDKN2B-AS1 are associated with lower intraocular pressure, normal-tension glaucoma, and advanced glaucoma. Ophthalmology. 2012, 119: 1539-1545. 10.1016\/j.ophtha.2012.02.004.","journal-title":"Ophthalmology"},{"key":"87_CR63","doi-asserted-by":"publisher","first-page":"1819","DOI":"10.1016\/j.ophtha.2012.02.044","volume":"119","author":"F Mabuchi","year":"2012","unstructured":"Mabuchi F, Sakurada Y, Kashiwagi K, Yamagata Z, Iijima H, Tsukahara S: Association between genetic variants associated with vertical cup-to-disc ratio and phenotypic features of primary open-angle glaucoma. Ophthalmology. 2012, 119: 1819-1825. 10.1016\/j.ophtha.2012.02.044.","journal-title":"Ophthalmology"},{"key":"87_CR64","doi-asserted-by":"publisher","first-page":"e40107","DOI":"10.1371\/journal.pone.0040107","volume":"7","author":"M Takamoto","year":"2012","unstructured":"Takamoto M, Kaburaki T, Mabuchi A, Araie M, Amano S, Aihara M, Tomidokoro A, Iwase A, Mabuchi F, Kashiwagi K: Common variants on chromosome 9p21 are associated with normal tension glaucoma. PLoS One. 2012, 7: e40107-10.1371\/journal.pone.0040107.","journal-title":"PLoS One"},{"key":"87_CR65","doi-asserted-by":"publisher","first-page":"e1002654","DOI":"10.1371\/journal.pgen.1002654","volume":"8","author":"JL Wiggs","year":"2012","unstructured":"Wiggs JL, Yaspan BL, Hauser MA, Kang JH, Allingham RR, Olson LM, Abdrabou W, Fan BJ, Wang DY, Brodeur W: Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma. PLoS Genet. 2012, 8: e1002654-10.1371\/journal.pgen.1002654.","journal-title":"PLoS Genet"},{"key":"87_CR66","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1016\/j.ajo.2012.04.023","volume":"154","author":"DP Dimasi","year":"2012","unstructured":"Dimasi DP, Burdon KP, Hewitt AW, Fitzgerald J, Wang JJ, Healey PR, Mitchell P, Mackey DA, Craig JE: Genetic investigation into the endophenotypic status of central corneal thickness and optic disc parameters in relation to open-angle glaucoma. Am J Ophthalmol. 2012, 154: 833-842. 10.1016\/j.ajo.2012.04.023.","journal-title":"Am J Ophthalmol"},{"key":"87_CR67","doi-asserted-by":"publisher","first-page":"e1000978","DOI":"10.1371\/journal.pgen.1000978","volume":"6","author":"WD Ramdas","year":"2010","unstructured":"Ramdas WD, van Koolwijk LM, Ikram MK, Jansonius NM, De Jong PT, Bergen AA, Isaacs A, Amin N, Aulchenko YS, Wolfs RC: A genome-wide association study of optic disc parameters. PLoS Genet. 2010, 6: e1000978-10.1371\/journal.pgen.1000978.","journal-title":"PLoS Genet"},{"issue":"Suppl 5","key":"87_CR68","doi-asserted-by":"publisher","first-page":"S13","DOI":"10.1097\/IJG.0b013e31829349bf","volume":"22","author":"JB Jonas","year":"2013","unstructured":"Jonas JB, Wang N: Intracranial pressure and glaucoma. J Glaucoma. 2013, 22 (Suppl 5): S13-S14.","journal-title":"J Glaucoma"},{"key":"87_CR69","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1136\/bjophthalmol-2011-300663","volume":"96","author":"HE Killer","year":"2012","unstructured":"Killer HE, Miller NR, Flammer J, Meyer P, Weinreb RN, Remonda L, Jaggi GP: Cerebrospinal fluid exchange in the optic nerve in normal-tension glaucoma. Br J Ophthalmol. 2012, 96: 544-548. 10.1136\/bjophthalmol-2011-300663.","journal-title":"Br J Ophthalmol"},{"key":"87_CR70","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1016\/j.ajo.2013.03.003","volume":"156","author":"P Wostyn","year":"2013","unstructured":"Wostyn P, De GV, Van DD, Audenaert K, De Deyn PP: Senescent changes in cerebrospinal fluid circulatory physiology and their role in the pathogenesis of normal-tension glaucoma. Am J Ophthalmol. 2013, 156: 5-14. 10.1016\/j.ajo.2013.03.003.","journal-title":"Am J Ophthalmol"},{"key":"87_CR71","doi-asserted-by":"publisher","first-page":"1699","DOI":"10.1016\/0024-3205(83)90831-7","volume":"32","author":"GC Chiou","year":"1983","unstructured":"Chiou GC: Effects of alpha 1 and alpha 2 activation of adrenergic receptors on aqueous humor dynamics. Life Sci. 1983, 32: 1699-1704. 10.1016\/0024-3205(83)90831-7.","journal-title":"Life Sci"},{"key":"87_CR72","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S0022-3565(25)31573-9","volume":"208","author":"JR Haywood","year":"1979","unstructured":"Haywood JR, Vogh BP: Some measurements of autonomic nervous system influence on production of cerebrospinal fluid in the cat. J Pharmacol Exp Ther. 1979, 208: 341-346.","journal-title":"J Pharmacol Exp Ther"},{"key":"87_CR73","doi-asserted-by":"publisher","first-page":"974","DOI":"10.1227\/00006123-199306000-00016","volume":"32","author":"JM McCormick","year":"1993","unstructured":"McCormick JM, McCormick PW, Zabramski JM, Spetzler RF: Intracranial pressure reduction by a central alpha-2 adrenoreceptor agonist after subarachnoid hemorrhage. Neurosurgery. 1993, 32: 974-979. 10.1227\/00006123-199306000-00016.","journal-title":"Neurosurgery"}],"container-title":["Fluids and Barriers of the CNS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/2045-8118-11-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T18:05:14Z","timestamp":1746122714000},"score":1,"resource":{"primary":{"URL":"https:\/\/fluidsbarrierscns.biomedcentral.com\/articles\/10.1186\/2045-8118-11-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,29]]},"references-count":73,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["87"],"URL":"https:\/\/doi.org\/10.1186\/2045-8118-11-2","relation":{},"ISSN":["2045-8118"],"issn-type":[{"value":"2045-8118","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,29]]},"assertion":[{"value":"19 November 2013","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 January 2014","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 January 2014","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"2"}}