{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T16:46:30Z","timestamp":1732034790978},"reference-count":64,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/2.0"},{"start":{"date-parts":[[2013,12,20]],"date-time":"2013-12-20T00:00:00Z","timestamp":1387497600000},"content-version":"vor","delay-in-days":19,"URL":"https:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cilia"],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1186\/2046-2530-2-18","type":"journal-article","created":{"date-parts":[[2013,12,20]],"date-time":"2013-12-20T18:24:28Z","timestamp":1387563868000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Enhanced response to pulmonary Streptococcus pneumoniae infection is associated with primary ciliary dyskinesia in mice lacking Pcdp1 and Spef2"],"prefix":"10.1186","volume":"2","author":[{"given":"Casey W","family":"McKenzie","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua M","family":"Klonoski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taylor","family":"Maier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Glenda","family":"Trujillo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter F","family":"Vitiello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor C","family":"Huber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lance","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,12,20]]},"reference":[{"key":"183_CR1","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1046\/j.1525-1497.2000.04429.x","volume":"15","author":"JA Brandenburg","year":"2000","unstructured":"Brandenburg JA, Marrie TJ, Coley CM, Singer DE, Obrosky DS, Kapoor WN, Fine MJ: Clinical presentation, processes and outcomes of care for patients with pneumococcal pneumonia. J Gen Intern Med. 2000, 15: 638-646. 10.1046\/j.1525-1497.2000.04429.x.","journal-title":"J Gen Intern Med"},{"key":"183_CR2","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.it.2003.12.006","volume":"25","author":"A Kadioglu","year":"2004","unstructured":"Kadioglu A, Andrew PW: The innate immune response to pneumococcal lung infection: the untold story. Trends Immunol. 2004, 25: 143-149. 10.1016\/j.it.2003.12.006.","journal-title":"Trends Immunol"},{"key":"183_CR3","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1055\/s-2005-925523","volume":"26","author":"A Ortqvist","year":"2005","unstructured":"Ortqvist A, Hedlund J, Kalin M: Streptococcus pneumoniae: epidemiology, risk factors, and clinical features. Semin Respir Crit Care Med. 2005, 26: 563-574. 10.1055\/s-2005-925523.","journal-title":"Semin Respir Crit Care Med"},{"key":"183_CR4","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/j.ijantimicag.2009.10.002","volume":"35","author":"E Calbo","year":"2010","unstructured":"Calbo E, Garau J: Of mice and men: innate immunity in pneumococcal pneumonia. Int J Antimicrob Agents. 2010, 35: 107-113. 10.1016\/j.ijantimicag.2009.10.002.","journal-title":"Int J Antimicrob Agents"},{"key":"183_CR5","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1172\/JCI0215217","volume":"109","author":"MR Knowles","year":"2002","unstructured":"Knowles MR, Boucher RC: Mucus clearance as a primary innate defense mechanism for mammalian airways. J Clin Invest. 2002, 109: 571-577.","journal-title":"J Clin Invest"},{"key":"183_CR6","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1080\/01926230601060025","volume":"35","author":"A Livraghi","year":"2007","unstructured":"Livraghi A, Randell SH: Cystic fibrosis and other respiratory diseases of impaired mucus clearance. Toxicol Pathol. 2007, 35: 116-129. 10.1080\/01926230601060025.","journal-title":"Toxicol Pathol"},{"key":"183_CR7","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1165\/rcmb.2006-0082SF","volume":"35","author":"SH Randell","year":"2006","unstructured":"Randell SH, Boucher RC: Effective mucus clearance is essential for respiratory health. Am J Respir Cell Mol Biol. 2006, 35: 20-28. 10.1165\/rcmb.2006-0082SF.","journal-title":"Am J Respir Cell Mol Biol"},{"key":"183_CR8","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1002\/path.1652","volume":"204","author":"BA Afzelius","year":"2004","unstructured":"Afzelius BA: Cilia-related diseases. J Pathol. 2004, 204: 470-477. 10.1002\/path.1652.","journal-title":"J Pathol"},{"key":"183_CR9","doi-asserted-by":"publisher","first-page":"1136","DOI":"10.1136\/adc.2006.096958","volume":"92","author":"A Bush","year":"2007","unstructured":"Bush A, Chodhari R, Collins N, Copeland F, Hall P, Harcourt J, Hariri M, Hogg C, Lucas J, Mitchison HM, O'Callaghan C, Phillips G: Primary ciliary dyskinesia: current state of the art. Arch Dis Child. 2007, 92: 1136-1140. 10.1136\/adc.2006.096958.","journal-title":"Arch Dis Child"},{"issue":"1","key":"183_CR10","doi-asserted-by":"publisher","first-page":"R27","DOI":"10.1093\/hmg\/ddg061","volume":"12","author":"I Ibanez-Tallon","year":"2003","unstructured":"Ibanez-Tallon I, Heintz N, Omran H: To beat or not to beat: roles of cilia in development and disease. Hum Mol Genet. 2003, 12 (1): R27-R35.","journal-title":"Hum Mol Genet"},{"key":"183_CR11","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.gene.2010.11.006","volume":"473","author":"L Lee","year":"2011","unstructured":"Lee L: Mechanisms of mammalian ciliary motility: insights from primary ciliary dyskinesia genetics. Gene. 2011, 473: 57-66. 10.1016\/j.gene.2010.11.006.","journal-title":"Gene"},{"key":"183_CR12","doi-asserted-by":"publisher","first-page":"1117","DOI":"10.1002\/jnr.23238","volume":"91","author":"L Lee","year":"2013","unstructured":"Lee L: Riding the wave of ependymal cilia: genetic susceptibility to hydrocephalus in primary ciliary dyskinesia. J Neurosci Res. 2013, 91: 1117-1132. 10.1002\/jnr.23238.","journal-title":"J Neurosci Res"},{"key":"183_CR13","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1097\/GIM.0b013e3181a53562","volume":"11","author":"MW Leigh","year":"2009","unstructured":"Leigh MW, Pittman JE, Carson JL, Ferkol TW, Dell SD, Davis SD, Knowles MR, Zariwala MA: Clinical and genetic aspects of primary ciliary dyskinesia\/Kartagener syndrome. Genet Med. 2009, 11: 473-487. 10.1097\/GIM.0b013e3181a53562.","journal-title":"Genet Med"},{"key":"183_CR14","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1097\/00000441-200101000-00002","volume":"321","author":"MJ Cowan","year":"2001","unstructured":"Cowan MJ, Gladwin MT, Shelhamer JH: Disorders of ciliary motility. Am J Med Sci. 2001, 321: 3-10. 10.1097\/00000441-200101000-00002.","journal-title":"Am J Med Sci"},{"key":"183_CR15","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1053\/j.semperi.2005.11.001","volume":"30","author":"T Ferkol","year":"2006","unstructured":"Ferkol T, Leigh M: Primary ciliary dyskinesia and newborn respiratory distress. Semin Perinatol. 2006, 30: 335-340. 10.1053\/j.semperi.2005.11.001.","journal-title":"Semin Perinatol"},{"key":"183_CR16","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1089\/jamp.2007.0659","volume":"21","author":"MA Mall","year":"2008","unstructured":"Mall MA: Role of cilia, mucus, and airway surface liquid in mucociliary dysfunction: lessons from mouse models. J Aerosol Med Pulm Drug Deliv. 2008, 21: 13-24. 10.1089\/jamp.2007.0659.","journal-title":"J Aerosol Med Pulm Drug Deliv"},{"key":"183_CR17","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1513\/pats.201103-024SD","volume":"8","author":"SD Sagel","year":"2011","unstructured":"Sagel SD, Davis SD, Campisi P, Dell SD: Update of respiratory tract disease in children with primary ciliary dyskinesia. Proc Am Thorac Soc. 2011, 8: 438-443. 10.1513\/pats.201103-024SD.","journal-title":"Proc Am Thorac Soc"},{"key":"183_CR18","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1089\/jam.2006.19.110","volume":"19","author":"W Stannard","year":"2006","unstructured":"Stannard W, O\u2019Callaghan C: Ciliary function and the role of cilia in clearance. J Aerosol Med. 2006, 19: 110-115. 10.1089\/jam.2006.19.110.","journal-title":"J Aerosol Med"},{"key":"183_CR19","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1002\/ppul.1950100104","volume":"10","author":"EG Barlocco","year":"1991","unstructured":"Barlocco EG, Valletta EA, Canciani M, Lungarella G, Gardi C, De Santi MM, Mastella G: Ultrastructural ciliary defects in children with recurrent infections of the lower respiratory tract. Pediatr Pulmonol. 1991, 10: 11-17. 10.1002\/ppul.1950100104.","journal-title":"Pediatr Pulmonol"},{"key":"183_CR20","doi-asserted-by":"publisher","first-page":"2376","DOI":"10.1183\/09031936.97.10102376","volume":"10","author":"A Ellerman","year":"1997","unstructured":"Ellerman A, Bisgaard H: Longitudinal study of lung function in a cohort of primary ciliary dyskinesia. Eur Respir J. 1997, 10: 2376-2379. 10.1183\/09031936.97.10102376.","journal-title":"Eur Respir J"},{"key":"183_CR21","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1007\/s004310050843","volume":"157","author":"J Hellinckx","year":"1998","unstructured":"Hellinckx J, Demedts M, De Boeck K: Primary ciliary dyskinesia: evolution of pulmonary function. Eur J Pediatr. 1998, 157: 422-426. 10.1007\/s004310050843.","journal-title":"Eur J Pediatr"},{"key":"183_CR22","doi-asserted-by":"publisher","first-page":"1332","DOI":"10.1183\/09031936.99.14613329","volume":"14","author":"S Homma","year":"1999","unstructured":"Homma S, Kawabata M, Kishi K, Tsuboi E, Narui K, Nakatani T, Saiki S, Nakata K: Bronchiolitis in Kartagener\u2019s syndrome. Eur Respir J. 1999, 14: 1332-1339. 10.1183\/09031936.99.14613329.","journal-title":"Eur Respir J"},{"key":"183_CR23","first-page":"102","volume":"127","author":"H Levison","year":"1983","unstructured":"Levison H, Mindorff CM, Chao J, Turner JA, Sturgess JM, Stringer DA: Pathophysiology of the ciliary motility syndromes. Eur J Respir Dis Suppl. 1983, 127: 102-117.","journal-title":"Eur J Respir Dis Suppl"},{"key":"183_CR24","doi-asserted-by":"publisher","first-page":"816","DOI":"10.1002\/ppul.22577","volume":"47","author":"ML Magnin","year":"2012","unstructured":"Magnin ML, Cros P, Beydon N, Mahloul M, Tamalet A, Escudier E, Clement A, Le Pointe HD, Blanchon S: Longitudinal lung function and structural changes in children with primary ciliary dyskinesia. Pediatr Pulmonol. 2012, 47: 816-825. 10.1002\/ppul.22577.","journal-title":"Pediatr Pulmonol"},{"key":"183_CR25","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1186\/1824-7288-35-24","volume":"35","author":"S Montella","year":"2009","unstructured":"Montella S, Santamaria F, Salvatore M, Maglione M, Iacotucci P, De Santi MM, Mollica C: Lung disease assessment in primary ciliary dyskinesia: a comparison between chest high-field magnetic resonance imaging and high-resolution computed tomography findings. Ital J Pediatr. 2009, 35: 24-10.1186\/1824-7288-35-24.","journal-title":"Ital J Pediatr"},{"key":"183_CR26","first-page":"129","volume":"127","author":"B Mossberg","year":"1983","unstructured":"Mossberg B, Camner P, Afzelius BA: The immotile-cilia syndrome compared to other obstructive lung diseases: a clue to their pathogenesis. Eur J Respir Dis Suppl. 1983, 127: 129-136.","journal-title":"Eur J Respir Dis Suppl"},{"key":"183_CR27","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1164\/rccm.200303-365OC","volume":"169","author":"PG Noone","year":"2004","unstructured":"Noone PG, Leigh MW, Sannuti A, Minnix SL, Carson JL, Hazucha M, Zariwala MA, Knowles MR: Primary ciliary dyskinesia: diagnostic and phenotypic features. Am J Respir Crit Care Med. 2004, 169: 459-467. 10.1164\/rccm.200303-365OC.","journal-title":"Am J Respir Crit Care Med"},{"key":"183_CR28","first-page":"118","volume":"127","author":"M Pedersen","year":"1983","unstructured":"Pedersen M, Stafanger G: Bronchopulmonary symptoms in primary ciliary dyskinesia. A clinical study of 27 patients. Eur J Respir Dis Suppl. 1983, 127: 118-128.","journal-title":"Eur J Respir Dis Suppl"},{"key":"183_CR29","doi-asserted-by":"publisher","first-page":"993","DOI":"10.1136\/thoraxjnl-2011-200137","volume":"67","author":"M Pifferi","year":"2012","unstructured":"Pifferi M, Bush A, Pioggia G, Caramella D, Tartarisco G, Di Cicco M, Zangani M, Chinellato I, Maggi F, Tezza G, Macchia P, Boner A: Evaluation of pulmonary disease using static lung volumes in primary ciliary dyskinesia. Thorax. 2012, 67: 993-999. 10.1136\/thoraxjnl-2011-200137.","journal-title":"Thorax"},{"key":"183_CR30","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1378\/chest.07-2812","volume":"134","author":"F Santamaria","year":"2008","unstructured":"Santamaria F, Montella S, Tiddens HA, Guidi G, Casotti V, Maglione M, de Jong PA: Structural and functional lung disease in primary ciliary dyskinesia. Chest. 2008, 134: 351-357. 10.1378\/chest.07-2812.","journal-title":"Chest"},{"key":"183_CR31","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1542\/peds.67.6.805","volume":"67","author":"JA Turner","year":"1981","unstructured":"Turner JA, Corkey CW, Lee JY, Levison H, Sturgess J: Clinical expressions of immotile cilia syndrome. Pediatrics. 1981, 67: 805-810.","journal-title":"Pediatrics"},{"key":"183_CR32","doi-asserted-by":"publisher","first-page":"1262","DOI":"10.1164\/rccm.200811-1731OC","volume":"181","author":"JK Marthin","year":"2010","unstructured":"Marthin JK, Petersen N, Skovgaard LT, Nielsen KG: Lung function in patients with primary ciliary dyskinesia: a cross-sectional and 3-decade longitudinal study. Am J Respir Crit Care Med. 2010, 181: 1262-1268. 10.1164\/rccm.200811-1731OC.","journal-title":"Am J Respir Crit Care Med"},{"key":"183_CR33","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1378\/chest.129.1.118","volume":"129","author":"A Bush","year":"2006","unstructured":"Bush A, Payne D, Pike S, Jenkins G, Henke MO, Rubin BK: Mucus properties in children with primary ciliary dyskinesia: comparison with cystic fibrosis. Chest. 2006, 129: 118-123. 10.1378\/chest.129.1.118.","journal-title":"Chest"},{"key":"183_CR34","doi-asserted-by":"publisher","first-page":"7993","DOI":"10.1128\/MCB.22.22.7993-8004.2002","volume":"22","author":"Z Zhang","year":"2002","unstructured":"Zhang Z, Sapiro R, Kapfhamer D, Bucan M, Bray J, Chennathukuzhi V, McNamara P, Curtis A, Zhang M, Blanchette-Mackie EJ, Strauss JF: A sperm-associated WD repeat protein orthologous to Chlamydomonas PF20 associates with Spag6, the mammalian orthologue of Chlamydomonas PF16. Mol Cell Biol. 2002, 22: 7993-8004. 10.1128\/MCB.22.22.7993-8004.2002.","journal-title":"Mol Cell Biol"},{"key":"183_CR35","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1002\/cm.20189","volume":"64","author":"Z Zhang","year":"2007","unstructured":"Zhang Z, Tang W, Zhou R, Shen X, Wei Z, Patel AM, Povlishock JT, Bennett J, Strauss JF: Accelerated mortality from hydrocephalus and pneumonia in mice with a combined deficiency of SPAG6 and SPAG16L reveals a functional interrelationship between the two central apparatus proteins. Cell Motil Cytoskeleton. 2007, 64: 360-376. 10.1002\/cm.20189.","journal-title":"Cell Motil Cytoskeleton"},{"key":"183_CR36","doi-asserted-by":"publisher","first-page":"6298","DOI":"10.1128\/MCB.22.17.6298-6305.2002","volume":"22","author":"R Sapiro","year":"2002","unstructured":"Sapiro R, Kostetskii I, Olds-Clarke P, Gerton GL, Radice GL, Strauss IJ: Male infertility, impaired sperm motility, and hydrocephalus in mice deficient in sperm-associated antigen 6. Mol Cell Biol. 2002, 22: 6298-6305. 10.1128\/MCB.22.17.6298-6305.2002.","journal-title":"Mol Cell Biol"},{"key":"183_CR37","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1095\/biolreprod.105.049254","volume":"74","author":"Z Zhang","year":"2006","unstructured":"Zhang Z, Kostetskii I, Tang W, Haig-Ladewig L, Sapiro R, Wei Z, Patel AM, Bennett J, Gerton GL, Moss SB, Radice GL, Strauss JF: Deficiency of SPAG16L causes male infertility associated with impaired sperm motility. Biol Reprod. 2006, 74: 751-759. 10.1095\/biolreprod.105.049254.","journal-title":"Biol Reprod"},{"key":"183_CR38","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1165\/rcmb.2012-0362OC","volume":"48","author":"ME Teves","year":"2013","unstructured":"Teves ME, Zhang Z, Costanzo RM, Henderson SC, Corwin FD, Zweit J, Sundaresan G, Subler M, Salloum FN, Rubin BK, Strauss JF: Sperm-associated antigen-17 gene is essential for motile cilia function and neonatal survival. Am J Respir Cell Mol Biol. 2013, 48: 765-772. 10.1165\/rcmb.2012-0362OC.","journal-title":"Am J Respir Cell Mol Biol"},{"key":"183_CR39","doi-asserted-by":"publisher","first-page":"e13600","DOI":"10.1371\/journal.pone.0013600","volume":"5","author":"D Love","year":"2010","unstructured":"Love D, Li FQ, Burke MC, Cyge B, Ohmitsu M, Cabello J, Larson JE, Brody SL, Cohen JC, Takemaru K: Altered lung morphogenesis, epithelial cell differentiation and mechanics in mice deficient in the Wnt\/beta-catenin antagonist Chibby. PLoS One. 2010, 5: e13600-10.1371\/journal.pone.0013600.","journal-title":"PLoS One"},{"key":"183_CR40","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1083\/jcb.200809144","volume":"185","author":"VA Voronina","year":"2009","unstructured":"Voronina VA, Takemaru K, Treuting P, Love D, Grubb BR, Hajjar AM, Adams A, Li FQ, Moon RT: Inactivation of Chibby affects function of motile airway cilia. J Cell Biol. 2009, 185: 225-233. 10.1083\/jcb.200809144.","journal-title":"J Cell Biol"},{"key":"183_CR41","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1128\/MCB.00354-07","volume":"28","author":"L Lee","year":"2008","unstructured":"Lee L, Campagna DR, Pinkus JL, Mulhern H, Wyatt TA, Sisson JH, Pavlik JA, Pinkus GS, Fleming MD: Primary ciliary dyskinesia in mice lacking the novel ciliary protein Pcdp1. Mol Cell Biol. 2008, 28: 949-957. 10.1128\/MCB.00354-07.","journal-title":"Mol Cell Biol"},{"key":"183_CR42","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1095\/biolreprod.111.091132","volume":"85","author":"A Sironen","year":"2011","unstructured":"Sironen A, Kotaja N, Mulhern H, Wyatt TA, Sisson JH, Pavlik JA, Miiluniemi M, Fleming MD, Lee L: Loss of SPEF2 function in mice results in spermatogenesis defects and primary ciliary dyskinesia. Biol Reprod. 2011, 85: 690-701. 10.1095\/biolreprod.111.091132.","journal-title":"Biol Reprod"},{"key":"183_CR43","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1513\/pats.200508-090JS","volume":"2","author":"TR Martin","year":"2005","unstructured":"Martin TR, Frevert CW: Innate immunity in the lungs. Proc Am Thorac Soc. 2005, 2: 403-411. 10.1513\/pats.200508-090JS.","journal-title":"Proc Am Thorac Soc"},{"key":"183_CR44","doi-asserted-by":"publisher","first-page":"2111","DOI":"10.1007\/s10439-008-9538-4","volume":"36","author":"W Mitzner","year":"2008","unstructured":"Mitzner W, Fallica J, Bishai J: Anisotropic nature of mouse lung parenchyma. Ann Biomed Eng. 2008, 36: 2111-2120. 10.1007\/s10439-008-9538-4.","journal-title":"Ann Biomed Eng"},{"key":"183_CR45","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1038\/nmeth.2089","volume":"9","author":"CA Schneider","year":"2012","unstructured":"Schneider CA, Rasband WS, Eliceiri KW: NIH Image to ImageJ: 25\u00a0years of image analysis. Nat Methods. 2012, 9: 671-675. 10.1038\/nmeth.2089.","journal-title":"Nat Methods"},{"key":"183_CR46","doi-asserted-by":"publisher","first-page":"e26587","DOI":"10.1371\/journal.pone.0026587","volume":"6","author":"CJ Sanchez","year":"2011","unstructured":"Sanchez CJ, Hinojosa CA, Shivshankar P, Hyams C, Camberlein E, Brown JS, Orihuela CJ: Changes in capsular serotype alter the surface exposure of pneumococcal adhesins and impact virulence. PLoS One. 2011, 6: e26587-10.1371\/journal.pone.0026587.","journal-title":"PLoS One"},{"key":"183_CR47","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1083\/jcb.200912009","volume":"189","author":"CG DiPetrillo","year":"2010","unstructured":"DiPetrillo CG, Smith EF: Pcdp1 is a central apparatus protein that binds Ca(2+)-calmodulin and regulates ciliary motility. J Cell Biol. 2010, 189: 601-612. 10.1083\/jcb.200912009.","journal-title":"J Cell Biol"},{"key":"183_CR48","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1095\/biolreprod.108.074971","volume":"82","author":"A Sironen","year":"2010","unstructured":"Sironen A, Hansen J, Thomsen B, Andersson M, Vilkki J, Toppari J, Kotaja N: Expression of SPEF2 during mouse spermatogenesis and identification of IFT20 as an interacting protein. Biol Reprod. 2010, 82: 580-590. 10.1095\/biolreprod.108.074971.","journal-title":"Biol Reprod"},{"key":"183_CR49","doi-asserted-by":"publisher","first-page":"4179","DOI":"10.1242\/jcs.01297","volume":"117","author":"H Zhang","year":"2004","unstructured":"Zhang H, Mitchell DR: Cpc1, a Chlamydomonas central pair protein with an adenylate kinase domain. J Cell Sci. 2004, 117: 4179-4188. 10.1242\/jcs.01297.","journal-title":"J Cell Sci"},{"key":"183_CR50","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1099\/0022-1317-49-12-1057","volume":"49","author":"SH Gillespie","year":"2000","unstructured":"Gillespie SH, Balakrishnan I: Pathogenesis of pneumococcal infection. J Med Microbiol. 2000, 49: 1057-1067.","journal-title":"J Med Microbiol"},{"key":"183_CR51","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1128\/IAI.68.2.492-501.2000","volume":"68","author":"A Kadioglu","year":"2000","unstructured":"Kadioglu A, Gingles NA, Grattan K, Kerr A, Mitchell TJ, Andrew PW: Host cellular immune response to pneumococcal lung infection in mice. Infect Immun. 2000, 68: 492-501. 10.1128\/IAI.68.2.492-501.2000.","journal-title":"Infect Immun"},{"key":"183_CR52","doi-asserted-by":"publisher","first-page":"1745","DOI":"10.1097\/00003246-199909000-00008","volume":"27","author":"C Monton","year":"1999","unstructured":"Monton C, Torres A, El-Ebiary M, Filella X, Xaubet A, de la Bellacasa JP: Cytokine expression in severe pneumonia: a bronchoalveolar lavage study. Crit Care Med. 1999, 27: 1745-1753. 10.1097\/00003246-199909000-00008.","journal-title":"Crit Care Med"},{"key":"183_CR53","doi-asserted-by":"publisher","first-page":"1281","DOI":"10.7150\/ijbs.4874","volume":"8","author":"M Rincon","year":"2012","unstructured":"Rincon M, Irvin CG: Role of IL-6 in asthma and other inflammatory pulmonary diseases. Int J Biol Sci. 2012, 8: 1281-1290.","journal-title":"Int J Biol Sci"},{"key":"183_CR54","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1086\/514062","volume":"176","author":"T van der Poll","year":"1997","unstructured":"van der Poll T, Keogh CV, Guirao X, Buurman WA, Kopf M, Lowry SF: Interleukin-6 gene-deficient mice show impaired defense against pneumococcal pneumonia. J Infect Dis. 1997, 176: 439-444. 10.1086\/514062.","journal-title":"J Infect Dis"},{"key":"183_CR55","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1016\/j.canlet.2012.10.014","volume":"328","author":"WM Chu","year":"2013","unstructured":"Chu WM: Tumor necrosis factor. Cancer Lett. 2013, 328: 222-225. 10.1016\/j.canlet.2012.10.014.","journal-title":"Cancer Lett"},{"key":"183_CR56","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.immuni.2013.01.004","volume":"38","author":"W Liao","year":"2013","unstructured":"Liao W, Lin JX, Leonard WJ: Interleukin-2 at the crossroads of effector responses, tolerance, and immunotherapy. Immunity. 2013, 38: 13-25. 10.1016\/j.immuni.2013.01.004.","journal-title":"Immunity"},{"issue":"A","key":"183_CR57","doi-asserted-by":"publisher","first-page":"S47","DOI":"10.1016\/S1526-0542(04)90010-3","volume":"5","author":"JG Martin","year":"2004","unstructured":"Martin JG, Suzuki M, Ramos-Barbon D, Isogai S: T cell cytokines: animal models. Paediatr Respir Rev. 2004, 5 (A): S47-S51.","journal-title":"Paediatr Respir Rev"},{"key":"183_CR58","doi-asserted-by":"publisher","first-page":"986","DOI":"10.1016\/j.jaci.2009.03.033","volume":"123","author":"C Nembrini","year":"2009","unstructured":"Nembrini C, Marsland BJ, Kopf M: IL-17-producing T cells in lung immunity and inflammation. J Allergy Clin Immunol. 2009, 123: 986-994. 10.1016\/j.jaci.2009.03.033. Quiz 995\u2013996","journal-title":"J Allergy Clin Immunol"},{"key":"183_CR59","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1016\/j.cytogfr.2010.10.002","volume":"21","author":"JM Reynolds","year":"2010","unstructured":"Reynolds JM, Angkasekwinai P, Dong C: IL-17 family member cytokines: regulation and function in innate immunity. Cytokine Growth Factor Rev. 2010, 21: 413-423. 10.1016\/j.cytogfr.2010.10.002.","journal-title":"Cytokine Growth Factor Rev"},{"key":"183_CR60","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1084\/jem.194.4.519","volume":"194","author":"P Ye","year":"2001","unstructured":"Ye P, Rodriguez FH, Kanaly S, Stocking KL, Schurr J, Schwarzenberger P, Oliver P, Huang W, Zhang P, Zhang J, Shellito JE, Bagby GJ, Nelson S, Charrier K, Peschon JJ, Kolls JK: Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense. J Exp Med. 2001, 194: 519-527. 10.1084\/jem.194.4.519.","journal-title":"J Exp Med"},{"key":"183_CR61","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/S0065-2776(10)05004-2","volume":"105","author":"K Fujio","year":"2010","unstructured":"Fujio K, Okamura T, Yamamoto K: The family of IL-10-secreting CD4+ T cells. Adv Immunol. 2010, 105: 99-130.","journal-title":"Adv Immunol"},{"key":"183_CR62","doi-asserted-by":"publisher","first-page":"683","DOI":"10.1146\/annurev.immunol.19.1.683","volume":"19","author":"KW Moore","year":"2001","unstructured":"Moore KW, de Waal MR, Coffman RL, O\u2019Garra A: Interleukin-10 and the interleukin-10 receptor. Annu Rev Immunol. 2001, 19: 683-765. 10.1146\/annurev.immunol.19.1.683.","journal-title":"Annu Rev Immunol"},{"key":"183_CR63","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1007\/s11882-996-0005-8","volume":"6","author":"Z Urry","year":"2006","unstructured":"Urry Z, Xystrakis E, Hawrylowicz CM: Interleukin-10-secreting regulatory T cells in allergy and asthma. Curr Allergy Asthma Rep. 2006, 6: 363-371. 10.1007\/s11882-996-0005-8.","journal-title":"Curr Allergy Asthma Rep"},{"key":"183_CR64","doi-asserted-by":"publisher","first-page":"994","DOI":"10.1093\/infdis\/174.5.994","volume":"174","author":"T van der Poll","year":"1996","unstructured":"van der Poll T, Marchant A, Keogh CV, Goldman M, Lowry SF: Interleukin-10 impairs host defense in murine pneumococcal pneumonia. J Infect Dis. 1996, 174: 994-1000. 10.1093\/infdis\/174.5.994.","journal-title":"J Infect Dis"}],"container-title":["Cilia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/2046-2530-2-18.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/2046-2530-2-18\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/2046-2530-2-18.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,20]],"date-time":"2022-03-20T11:17:53Z","timestamp":1647775073000},"score":1,"resource":{"primary":{"URL":"https:\/\/ciliajournal.biomedcentral.com\/articles\/10.1186\/2046-2530-2-18"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12]]},"references-count":64,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["183"],"URL":"https:\/\/doi.org\/10.1186\/2046-2530-2-18","relation":{},"ISSN":["2046-2530"],"issn-type":[{"value":"2046-2530","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12]]},"assertion":[{"value":"17 September 2013","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 December 2013","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 December 2013","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"18"}}