{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T11:47:41Z","timestamp":1771501661309,"version":"3.50.1"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2013,1,10]],"date-time":"2013-01-10T00:00:00Z","timestamp":1357776000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Health Inf Sci Syst"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>Kyoto Encyclopedia of Genes and Genomes (KEGG) is an online and integrated molecular database for several organisms. KEGG has been a highly useful site, helping domain scientists understand, research, study, and teach metabolisms by linking sequenced genomes to higher level systematic functions. KEGG databases are accessible through the web pages of the system, but the capabilities of the web interface are limited. Third party systems have been built over the KEGG data to provide extensive functionalities. However, there have been no attempts towards providing a tablet interface for KEGG data. Recognizing the rise of mobile technologies and the importance of tablets in education, this paper presents the design and implementation of iPathCase<jats:sup>KEGG<\/jats:sup>, an iPad interface for KEGG data, which is empowered with multiple browsing and visualization capabilities.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>iPathCase<jats:sup>KEGG<\/jats:sup> has been implemented and is available, free of charge, in the Apple App Store (locatable by searching for \u201cPathcase\u201d in the app store). The application provides browsing and interactive visualization functionalities on the KEGG data. Users can pick pathways, visualize them, and see detail pages of reactions and molecules using the multi-touch interface of iPad.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>iPathCase<jats:sup>KEGG<\/jats:sup> provides a mobile interface to access KEGG data. Interactive visualization and browsing functionalities let users to interact with the data in multiple ways. As the importance of tablets and their usage in research education continue to rise, we think iPathCase<jats:sup>KEGG<\/jats:sup> will be a useful tool for life science instructors and researchers.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/2047-2501-1-4","type":"journal-article","created":{"date-parts":[[2013,1,10]],"date-time":"2013-01-10T20:37:38Z","timestamp":1357850258000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["iPathCaseKEGG: An iPad interface for KEGG metabolic pathways"],"prefix":"10.1007","volume":"1","author":[{"given":"Stephen R","family":"Johnson","sequence":"first","affiliation":[]},{"given":"Xinjian","family":"Qi","sequence":"additional","affiliation":[]},{"given":"A Ercument","family":"Cicek","sequence":"additional","affiliation":[]},{"given":"Gultekin","family":"Ozsoyoglu","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2013,1,10]]},"reference":[{"key":"4_CR1","doi-asserted-by":"publisher","first-page":"D109","DOI":"10.1093\/nar\/gkr988","volume":"40","author":"M Kanehisa","year":"2012","unstructured":"Kanehisa M, Goto S, Sato Y, Furumichi M, Tanabe M: KEGG for integration and interpretation of large-scale molecular datasets. Nucleic Acids Res. 2012, 40: D109-D114. 10.1093\/nar\/gkr988.","journal-title":"Nucleic Acids Res"},{"key":"4_CR2","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1093\/nar\/28.1.27","volume":"28","author":"M Kanehisa","year":"2000","unstructured":"Kanehisa M, Goto S: KEGG: Kyoto Encyclopedia of Genes and Genomes. Nucleic Acids Res. 2000, 28: 27-30. 10.1093\/nar\/28.1.27.","journal-title":"Nucleic Acids Res"},{"issue":"21","key":"4_CR3","doi-asserted-by":"publisher","first-page":"2526","DOI":"10.1093\/bioinformatics\/btn459","volume":"24","author":"B Elliott","year":"2008","unstructured":"Elliott B, Kirac M, Cakmak A, Yavas G, Mayes S, Cheng E, Wang Y, Gupta C, Ozsoyoglu G, Ozsoyoglu ZM: PathCase: pathways database system. 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