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A fall in FEV1 of \u226510% in either challenge test was deemed positive for exercise-induced bronchoconstriction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fourteen (32%) athletes were atopic and 7 (16%) had a history of physician-diagnosed asthma. Absolute lung function values were significantly lower in patients of group 1 and 2 compared to group 3. Nine (20%) athletes were positive to EVH (8 paraplegics, 1 tetraplegic), and 8 (18%) athletes were positive to MCT (7 paraplegics, 1 tetraplegic). Fourteen (22.7%) subjects were positive to at least one challenge; only three athletes were positive to both tests. None of the athletes in group 3 had a positive test. Both challenge tests showed a significant association with physician-diagnosed asthma status (p\u2009=\u20090.0001). The positive and negative predictive value to diagnose physician-diagnosed asthma was 89% and 91% for EHV, and 75% and 86% for MCT, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>EVH and MCT can be used to identify, but especially exclude asthma in Paralympic athletes.<\/jats:p><\/jats:sec>","DOI":"10.1186\/2052-1847-5-7","type":"journal-article","created":{"date-parts":[[2013,4,15]],"date-time":"2013-04-15T17:00:10Z","timestamp":1366045210000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Bronchial hyperresponsiveness testing in athletes of the Swiss Paralympic team"],"prefix":"10.1186","volume":"5","author":[{"given":"Mirjam","family":"Osthoff","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franz","family":"Michel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Strupler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Miedinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne B","family":"Taegtmeyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f6rg D","family":"Leuppi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Perret","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,4,15]]},"reference":[{"key":"10_CR1","unstructured":"The International Paralympic Committee: http:\/\/www.paralympic.org (accessed Feb 19, 2012)"},{"key":"10_CR2","unstructured":"The International Olympic Committee: http:\/\/www.olympic.org\/Documents\/Reports\/EN\/en_report_1302.pdf (accessed Feb 19, 2012)"},{"key":"10_CR3","doi-asserted-by":"publisher","first-page":"732","DOI":"10.1097\/00005768-200004000-00003","volume":"32","author":"RL Wilber","year":"2000","unstructured":"Wilber RL, Rundell KW, Szmedra L, Jenkinson DM, Im J, Drake SD: Incidence of exercise-induced bronchospasm in olympic winter sport athletes. 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