{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T13:59:40Z","timestamp":1788184780903,"version":"build-2803163510"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2013,8,8]],"date-time":"2013-08-08T00:00:00Z","timestamp":1375920000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Hematol Oncol"],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1186\/2162-3619-2-22","type":"journal-article","created":{"date-parts":[[2013,8,9]],"date-time":"2013-08-09T00:14:30Z","timestamp":1376007270000},"source":"Crossref","is-referenced-by-count":2,"title":["Hairy cell leukemia in kidney transplantation: lesson from a rare disorder"],"prefix":"10.1186","volume":"2","author":[{"given":"Fabrizio","family":"Vinante","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Tomei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluigi","family":"Zaza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Zam\u00f2","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Lupo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,8,8]]},"reference":[{"key":"59_CR1","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1681\/ASN.V9112135","volume":"9","author":"FJ Van Der Woude","year":"1998","unstructured":"Van Der Woude FJ: Impact of renal cadaveric transplantation on survival in end-stage renal failure: evidence for reduced mortality risk compared with hemodialysis during long-term follow-up. J Am Soc Nephrol 1998, 9: 2135\u20132141.","journal-title":"J Am Soc Nephrol"},{"key":"59_CR2","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1056\/NEJM200003023420901","volume":"342","author":"S Hariharan","year":"2000","unstructured":"Hariharan S, Johnson CP, Bresnahan BA, Taranto SE, McIntosh MJ, Stablein D: Improved graft survival after renal transplantation in the United States, 1988 to 1996. N Engl J Med 2000, 342: 605\u2013612. 10.1056\/NEJM200003023420901","journal-title":"N Engl J Med"},{"key":"59_CR3","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1111\/j.1600-6143.2004.00332.x","volume":"4","author":"HU Meier-Kriesche","year":"2004","unstructured":"Meier-Kriesche HU, Schold JD, Srinivas TR, Kaplan B: Lack of improvement in renal allograft survival despite a marked decrease in acute rejection rates over the most recent era. Am J Transplant 2004, 4: 378\u2013383. 10.1111\/j.1600-6143.2004.00332.x","journal-title":"Am J Transplant"},{"key":"59_CR4","doi-asserted-by":"publisher","first-page":"905","DOI":"10.1111\/j.1600-6143.2004.00450.x","volume":"4","author":"BL Kasiske","year":"2004","unstructured":"Kasiske BL, Snyder JJ, Gilbertson DT, Wang C: Cancer after kidney transplantation in the United States. Am J Transplant 2004, 4: 905\u2013913. 10.1111\/j.1600-6143.2004.00450.x","journal-title":"Am J Transplant"},{"key":"59_CR5","doi-asserted-by":"publisher","first-page":"2823","DOI":"10.1001\/jama.296.23.2823","volume":"296","author":"CM Vajdic","year":"2006","unstructured":"Vajdic CM, McDonald SP, McCredie MR, Van Leeuwen MT, Stewart JH, Law M, Chapman JR, Webster AC, Kaldor JM, Grulich AE: Cancer incidence before and after kidney transplantation. JAMA 2006, 296: 2823\u20132831. 10.1001\/jama.296.23.2823","journal-title":"JAMA"},{"key":"59_CR6","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1007\/s11255-009-9558-5","volume":"42","author":"MA Marinella","year":"2010","unstructured":"Marinella MA: Hematologic abnormalities following renal transplantation. Int Urol Nephrol 2010, 42: 151\u2013164. 10.1007\/s11255-009-9558-5","journal-title":"Int Urol Nephrol"},{"key":"59_CR7","doi-asserted-by":"publisher","first-page":"888","DOI":"10.1097\/01.tp.0000203554.54242.56","volume":"81","author":"S Caillard","year":"2006","unstructured":"Caillard S, Agodoa LY, Bohen EM, Abbott KC: Myeloma, Hodgkin disease, and lymphoid leukemia after renal transplantation: characteristics, risk factors and prognosis. Transplantation 2006, 81: 888\u2013895. 10.1097\/01.tp.0000203554.54242.56","journal-title":"Transplantation"},{"key":"59_CR8","doi-asserted-by":"publisher","first-page":"2088","DOI":"10.1093\/oxfordjournals.ndt.a027106","volume":"11","author":"MF Mamzer-Bruneel","year":"1996","unstructured":"Mamzer-Bruneel MF, Legendre C, Hermine O, Flandrin G, Varet B, Kreis H: Hairy-cell leukaemia in a renal transplant recipient. Nephrol Dial Transplant 1996, 11: 2088\u20132089. 10.1093\/oxfordjournals.ndt.a027106","journal-title":"Nephrol Dial Transplant"},{"key":"59_CR9","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1080\/10428190500254505","volume":"47","author":"L Tsao","year":"2006","unstructured":"Tsao L, Chu EK, Bhagat G, Alobeid B: Development of hairy cell leukemia in a patient after cardiac transplantation. Leuk Lymphoma 2006, 47: 361\u2013363. 10.1080\/10428190500254505","journal-title":"Leuk Lymphoma"},{"key":"59_CR10","doi-asserted-by":"publisher","first-page":"714","DOI":"10.1111\/j.1365-2141.1993.tb03213.x","volume":"85","author":"A Staines","year":"1993","unstructured":"Staines A, Cartwright RA: Hairy cell leukaemia: descriptive epidemiology and a case\u2013control study. Br J Haematol 1993, 85: 714\u2013717. 10.1111\/j.1365-2141.1993.tb03213.x","journal-title":"Br J Haematol"},{"key":"59_CR11","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1182\/blood.V13.7.609.609","volume":"13","author":"BA Bouroncle","year":"1958","unstructured":"Bouroncle BA, Wiseman BK, Doan CA: Leukemic reticuloendotheliosis. Blood 1958, 13: 609\u2013630.","journal-title":"Blood"},{"key":"59_CR12","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1182\/blood.V70.5.1530.1530","volume":"70","author":"M Chilosi","year":"1987","unstructured":"Chilosi M, Semenzato G, Cetto G, Ambrosetti A, Fiore-Donati L, Perona G, Berton G, Lestani M, Scarpa A, Agostini C, Trentin L, Zambello R, Masciarelli M, Dazzi F, Vinante F, Caligaris-Cappio F, Pizzolo G: Soluble interleukin-2 receptors in the sera of patients with hairy cell leukemia: relationship with the effect of recombinant alpha-interferon therapy on clinical parameters and natural killer in vitro activity. Blood 1987, 70: 1530\u20131535.","journal-title":"Blood"},{"key":"59_CR13","first-page":"1051","volume":"9","author":"L Trentin","year":"1995","unstructured":"Trentin L, Pizzolo G, Zambello R, Agostini C, Morosato L, Sancetta R, Adami F, Vinante F, Chilosi M, Gallati H, Semenzato G: Leukemic cells in hairy-cell leukemia and B-cell chronic lymphocytic-leukemia release soluble TNF receptors. Leukemia 1995, 9: 1051\u20131055.","journal-title":"Leukemia"},{"key":"59_CR14","first-page":"385","volume":"15","author":"L Trentin","year":"1991","unstructured":"Trentin L, Zambello R, Pizzolo G, Vinante F, Ambrosetti A, Chisesi T, Vespignani M, Feruglio C, Adami F, Agostini C, Semenzato G: Tumor-necrosis-factor-alpha and B-cell growth-factor induce leukemic hairy-cells to proliferate in vitro. Cancer Detect Prev 1991, 15: 385\u2013390.","journal-title":"Cancer Detect Prev"},{"key":"59_CR15","doi-asserted-by":"publisher","first-page":"1025","DOI":"10.1046\/j.1365-2141.1998.00872.x","volume":"102","author":"F Vinante","year":"1998","unstructured":"Vinante F, Rigo A, Tecchio C, Morosato L, Nadali G, Ricetti MM, Krampera M, Zanolin E, Locatelli F, Gallati H, Chilosi M, Pizzolo G: Serum levels of p55 and p75 soluble TNF receptors in adult acute leukaemia at diagnosis: correlation with clinical and biological features and outcome. Br J Haematol 1998, 102: 1025\u20131034. 10.1046\/j.1365-2141.1998.00872.x","journal-title":"Br J Haematol"},{"key":"59_CR16","doi-asserted-by":"publisher","first-page":"4251","DOI":"10.1182\/blood-2010-01-262071","volume":"116","author":"SM Kornblau","year":"2010","unstructured":"Kornblau SM, McCue D, Singh N, Chen W, Estrov Z, Coombes KR: Recurrent expression signatures of cytokines and chemokines are present and are independently prognostic in acute myelogenous leukemia and myelodysplasia. Blood 2010, 116: 4251\u20134261. 10.1182\/blood-2010-01-262071","journal-title":"Blood"},{"key":"59_CR17","doi-asserted-by":"publisher","first-page":"3373","DOI":"10.2174\/138161212801227005","volume":"18","author":"T Robak","year":"2012","unstructured":"Robak T, Robak P: Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des 2012, 18: 3373\u20133388. 10.2174\/138161212801227005","journal-title":"Curr Pharm Des"},{"key":"59_CR18","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.mayocp.2011.09.001","volume":"87","author":"RR Naik","year":"2012","unstructured":"Naik RR, Saven A: My treatment approach to hairy cell leukemia. Mayo Clin Proc 2012, 87: 67\u201376. 10.1016\/j.mayocp.2011.09.001","journal-title":"Mayo Clin Proc"},{"key":"59_CR19","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.1093\/ndt\/gfn605","volume":"24","author":"S Domhan","year":"2009","unstructured":"Domhan S, Zeier M, Abdollahi A: Immunosuppressive therapy and post-transplant malignancy. Nephrol Dial Transplant 2009, 24: 1097\u20131103.","journal-title":"Nephrol Dial Transplant"},{"key":"59_CR20","doi-asserted-by":"publisher","first-page":"720","DOI":"10.1038\/nature03890","volume":"436","author":"C Michaloglou","year":"2005","unstructured":"Michaloglou C, Vredeveld LC, Soengas MS, Denoyelle C, Kuilman T, Van der Horst CM, Majoor DM, Shay JW, Mooi WJ, Peeper DS: BRAFE600-associated senescence-like cell cycle arrest of human naevi. Nature 2005, 436: 720\u2013724. 10.1038\/nature03890","journal-title":"Nature"},{"key":"59_CR21","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1097\/PAT.0b013e328360b61d","volume":"45","author":"S Pakneshan","year":"2013","unstructured":"Pakneshan S, Salajegheh A, Smith RA, Lam AK: Clinicopathological relevance of BRAF mutations in human cancer. Pathology 2013, 45: 356\u2013356.","journal-title":"Pathology"},{"key":"59_CR22","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1186\/1756-8722-6-30","volume":"6","author":"T Huang","year":"2013","unstructured":"Huang T, Karsy M, Zhuge J, Zhong M, Liu D: B-Raf and the inhibitors: from bench to bedside. J Hematol Oncol 2013, 6: 30. 10.1186\/1756-8722-6-30","journal-title":"J Hematol Oncol"},{"key":"59_CR23","doi-asserted-by":"publisher","first-page":"2305","DOI":"10.1056\/NEJMoa1014209","volume":"364","author":"E Tiacci","year":"2011","unstructured":"Tiacci E, Trifonov V, Schiavoni G, Holmes A, Kern W, Martelli MP, Pucciarini A, Bigerna B, Pacini R, Wells VA, Sportoletti P, Pettirossi V, Mannucci R, Elliott O, Liso A, Ambrosetti A, Pulsoni A, Forconi F, Trentin L, Semenzato G, Inghirami G, Capponi M, Di Raimondo F, Patti C, Arcaini L, Musto P, Pileri S, Haferlach C, Schnittger S, Pizzolo G, Fo\u00e0 R, Farinelli L, Haferlach T, Pasqualucci L, Rabadan R, Falini B: BRAF mutations in hairy-cell leukemia. N Engl J Med 2011, 364: 2305\u20132315. 10.1056\/NEJMoa1014209","journal-title":"N Engl J Med"},{"key":"59_CR24","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.gde.2006.12.005","volume":"17","author":"N Dhomen","year":"2007","unstructured":"Dhomen N, Marais R: New insight into BRAF mutations in cancer. Curr Opin Genet Dev 2007, 17: 31\u201339. 10.1016\/j.gde.2006.12.005","journal-title":"Curr Opin Genet Dev"},{"key":"59_CR25","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1038\/nature08996","volume":"465","author":"X Wu","year":"2010","unstructured":"Wu X, Nguyen BC, Dziunycz P, Chang S, Brooks Y, Lefort K, Hofbauer GF, Dotto GP: Calcineurin and ATF3: opposite roles in squamous skin cancer. Nature 2010, 465: 368\u2013372. 10.1038\/nature08996","journal-title":"Nature"},{"key":"59_CR26","doi-asserted-by":"publisher","first-page":"1055","DOI":"10.1101\/gad.187252.112","volume":"26","author":"LC Vredeveld","year":"2012","unstructured":"Vredeveld LC, Possik PA, Smit MA, Meissl K, Michaloglou C, Horlings HM, Ajouaou A, Kortman PC, Dankort D, McMahon M, Mooi WJ, Peeper DS: Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis. Genes Dev 2012, 26: 1055\u20131069. 10.1101\/gad.187252.112","journal-title":"Genes Dev"},{"key":"59_CR27","doi-asserted-by":"publisher","first-page":"297","DOI":"10.4161\/cc.7.3.5357","volume":"7","author":"H Medyouf","year":"2008","unstructured":"Medyouf H, Ghysdael J: The calcineurin\/NFAT signaling pathway: a novel therapeutic target in leukemia and solid tumors. Cell Cycle 2008, 7: 297\u2013303. 10.4161\/cc.7.3.5357","journal-title":"Cell Cycle"},{"key":"59_CR28","doi-asserted-by":"publisher","first-page":"1448","DOI":"10.1038\/sj.bjc.6605277","volume":"101","author":"RJ Flockhart","year":"2009","unstructured":"Flockhart RJ, Armstrong JL, Reynolds NJ, Lovat PE: NFAT signalling is a novel target of oncogenic BRAF in metastatic melanoma. Br J Cancer 2009, 101: 1448\u20131455. 10.1038\/sj.bjc.6605277","journal-title":"Br J Cancer"},{"key":"59_CR29","doi-asserted-by":"publisher","first-page":"16","DOI":"10.4161\/cc.6.1.3650","volume":"6","author":"M Buchholz","year":"2007","unstructured":"Buchholz M, Ellenrieder V: An emerging role for Ca2+\/calcineurin\/NFAT signaling in cancerogenesis. Cell Cycle 2007, 6: 16\u201319. 10.4161\/cc.6.1.3650","journal-title":"Cell Cycle"},{"key":"59_CR30","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1016\/j.coph.2008.06.014","volume":"8","author":"E Halilovic","year":"2008","unstructured":"Halilovic E, Solit DB: Therapeutic strategies for inhibiting oncogenic BRAF signaling. Curr Opin Pharmacol 2008, 8: 419\u2013426. 10.1016\/j.coph.2008.06.014","journal-title":"Curr Opin Pharmacol"},{"key":"59_CR31","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1097\/CCO.0b013e32835b639e","volume":"25","author":"NA Warfel","year":"2013","unstructured":"Warfel NA, El-Deiry WS: p21WAF1 and tumourigenesis: 20 years after. Curr Opin Oncol 2013, 25: 52\u201358. 10.1097\/CCO.0b013e32835b639e","journal-title":"Curr Opin Oncol"},{"key":"59_CR32","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1056\/NEJMe1111636","volume":"366","author":"AT Weeraratna","year":"2012","unstructured":"Weeraratna AT: RAF around the Edges \u2014 the paradox of BRAF inhibitors. N Engl J Med 2012, 366: 271\u2013273. 10.1056\/NEJMe1111636","journal-title":"N Engl J Med"},{"key":"59_CR33","doi-asserted-by":"publisher","first-page":"8200","DOI":"10.1158\/0008-5472.CAN-06-0809","volume":"66","author":"A Sharma","year":"2006","unstructured":"Sharma A, Tran MA, Liang S, Sharma AK, Amin S, Smith CD, Dong C, Robertson GP: Targeting mitogen-activated protein kinase\/extracellular signal-regulated kinase kinase in the mutant (V600E) B-Raf signaling cascade effectively inhibits melanoma lung metastases. Cancer Res 2006, 66: 8200\u20138209. 10.1158\/0008-5472.CAN-06-0809","journal-title":"Cancer Res"},{"key":"59_CR34","doi-asserted-by":"publisher","first-page":"2652","DOI":"10.1038\/jid.2012.179","volume":"132","author":"V Perotti","year":"2012","unstructured":"Perotti V, Baldassari P, Bersani I, Molla A, Vegetti C, Tassi E, Dal Col J, Dolcetti R, Anichini A, Mortarini R: NFATc2 is a potential therapeutic target in human melanoma. J Invest Dermatol 2012, 132: 2652\u20132660. 10.1038\/jid.2012.179","journal-title":"J Invest Dermatol"}],"container-title":["Experimental Hematology & Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/2162-3619-2-22.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/2162-3619-2-22\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/2162-3619-2-22.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,3]],"date-time":"2022-03-03T10:18:46Z","timestamp":1646302726000},"score":1,"resource":{"primary":{"URL":"https:\/\/ehoonline.biomedcentral.com\/articles\/10.1186\/2162-3619-2-22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8,8]]},"references-count":34,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["59"],"URL":"https:\/\/doi.org\/10.1186\/2162-3619-2-22","relation":{},"ISSN":["2162-3619"],"issn-type":[{"value":"2162-3619","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,8,8]]},"article-number":"22"}}