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The study was approved by the University of California Committee for the Protection of Human Subjects, the California Health and Human Services Agency Committee for the Protection of Human Subjects, and the institutional review boards of all participating hospitals. The biospecimens (neonatal blood specimens) and corresponding data used in this study were obtained from the California Biobank Program (SIS request number(s) 26, Section 6555(b)), 17 CCR. The California Department of Public Health is not responsible for the results or conclusions drawn by the authors of this publication.Both investigations obtained biospecimens from human subjects with informed written consent under protocols that had been approved by institutional review boards from all participating institutions. Written informed consent to participate in childhood leukemia research was obtained from the parents of all study subjects from the California Childhood Leukemia Study.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"334"}}