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It is a very time-consuming and error-prone task. In order to reduce the burden on physicians and improve the segmentation accuracy, the computer-aided detection (CAD) systems need to be developed. Due to the powerful feature learning ability of the deep learning technology, many deep learning-based methods have been applied to the brain tumor segmentation CAD systems and achieved satisfactory accuracy. However, deep learning neural networks have high computational complexity, and the brain tumor segmentation process consumes significant time. Therefore, in order to achieve the high segmentation accuracy of brain tumors and obtain the segmentation results efficiently, it is very demanding to speed up the segmentation process of brain tumors.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Compared with traditional computing platforms, the proposed FPGA accelerator has greatly improved the speed and the power consumption. Based on the BraTS19 and BraTS20 dataset, our FPGA-based brain tumor segmentation accelerator is 5.21 and 44.47 times faster than the TITAN V GPU and the Xeon CPU. In addition, by comparing energy efficiency, our design can achieve 11.22 and 82.33 times energy efficiency than GPU and CPU, respectively.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>We quantize and retrain the neural network for brain tumor segmentation and merge batch normalization layers to reduce the parameter size and computational complexity. The FPGA-based brain tumor segmentation accelerator is designed to map the quantized neural network model. The accelerator can increase the segmentation speed and reduce the power consumption on the basis of ensuring high accuracy which provides a new direction for the automatic segmentation and remote diagnosis of brain tumors.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12859-021-04347-6","type":"journal-article","created":{"date-parts":[[2021,9,7]],"date-time":"2021-09-07T09:03:15Z","timestamp":1631005395000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":48,"title":["MRI-based brain tumor segmentation using FPGA-accelerated neural network"],"prefix":"10.1186","volume":"22","author":[{"given":"Siyu","family":"Xiong","sequence":"first","affiliation":[]},{"given":"Guoqing","family":"Wu","sequence":"additional","affiliation":[]},{"given":"Xitian","family":"Fan","sequence":"additional","affiliation":[]},{"given":"Xuan","family":"Feng","sequence":"additional","affiliation":[]},{"given":"Zhongcheng","family":"Huang","sequence":"additional","affiliation":[]},{"given":"Wei","family":"Cao","sequence":"additional","affiliation":[]},{"given":"Xuegong","family":"Zhou","sequence":"additional","affiliation":[]},{"given":"Shijin","family":"Ding","sequence":"additional","affiliation":[]},{"given":"Jinhua","family":"Yu","sequence":"additional","affiliation":[]},{"given":"Lingli","family":"Wang","sequence":"additional","affiliation":[]},{"given":"Zhifeng","family":"Shi","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2021,9,7]]},"reference":[{"key":"4347_CR1","doi-asserted-by":"publisher","first-page":"1426","DOI":"10.1016\/j.mri.2013.05.002","volume":"31","author":"N Gordillo","year":"2013","unstructured":"Gordillo N, Montseny E, Sobrevilla P. 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