{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T18:14:01Z","timestamp":1765995241106},"reference-count":5,"publisher":"Springer Science and Business Media LLC","issue":"S2","license":[{"start":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T00:00:00Z","timestamp":1697587200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T00:00:00Z","timestamp":1697587200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Bioinformatics"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This Supplement issue, presents five research articles which are distributed, mainly due to the subject they address, from the 8th International Work-Conference on Bioinformatics and Biomedical Engineering (IWBBIO 2020), which was held on line, during September, 30th\u20132nd October, 2020. These contributions have been chosen because of their quality and the importance of their findings. Those contributions were then invited to participate in this supplement for the following journals of BMC: BMC Bioinformatics and BMC Genomics. In the present Editorial in BMC journal, we summarize the contributions that provide a clear overview of the thematic areas covered by the IWBBIO conference, ranging from theoretical\/review aspects to real-world applications of bioinformatic and biomedical engineering.<\/jats:p>","DOI":"10.1186\/s12859-023-05448-0","type":"journal-article","created":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T08:02:43Z","timestamp":1697616163000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Advances and challenges in Bioinformatics and Biomedical Engineering: IWBBIO 2020"],"prefix":"10.1186","volume":"24","author":[{"given":"Olga","family":"Valenzuela","sequence":"first","affiliation":[]},{"given":"Mario","family":"Cannataro","sequence":"additional","affiliation":[]},{"given":"Irena","family":"Rusur","sequence":"additional","affiliation":[]},{"given":"Jianxin","family":"Wang","sequence":"additional","affiliation":[]},{"given":"Zhongming","family":"Zhao","sequence":"additional","affiliation":[]},{"given":"Ignacio","family":"Rojas","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2023,10,18]]},"reference":[{"key":"5448_CR1","doi-asserted-by":"crossref","unstructured":"Rojas I, Valenzuela O, Rojas F, Herrera LJ, Ortu\u00f1o F. (eds.): Bioinformatics and Biomedical Engineering, IWBBIO2020. Lecture Notes in Computer Science, volume 12108; 2020.","DOI":"10.1007\/978-3-030-45385-5"},{"key":"5448_CR2","doi-asserted-by":"publisher","DOI":"10.1186\/s12859-022-04945-y","author":"D Grigoriadis","year":"2022","unstructured":"Grigoriadis D, Perdikopanis N, Georgakilas GK, Hatzigeorgiou AG. DeepTSS: multi-branch convolutional neural network for transcription start site identification from CAGE data. BMC Bioinform. 2022. https:\/\/doi.org\/10.1186\/s12859-022-04945-y.","journal-title":"BMC Bioinform"},{"key":"5448_CR3","doi-asserted-by":"publisher","DOI":"10.1186\/s12859-022-04582-5","author":"L Cappelletti","year":"2022","unstructured":"Cappelletti L, Petrini A, Gliozzo J, Casiraghi E, Schubach M, Kircher M, Valentini G. Boosting tissue-specific prediction of active cis-regulatory regions through deep learning and Bayesian optimization techniques. BMC Bioinform. 2022. https:\/\/doi.org\/10.1186\/s12859-022-04582-5.","journal-title":"BMC Bioinform"},{"key":"5448_CR4","doi-asserted-by":"publisher","DOI":"10.1186\/s12859-022-04958-7","author":"B Sarker","year":"2022","unstructured":"Sarker B, Khare N, Devignes MD, Aridhi S. Improving automatic GO annotation with semantic similarity. BMC Bioinform. 2022. https:\/\/doi.org\/10.1186\/s12859-022-04958-7.","journal-title":"BMC Bioinform"},{"key":"5448_CR5","doi-asserted-by":"publisher","DOI":"10.1186\/s12864-022-08550-4","author":"M Nykrynova","year":"2022","unstructured":"Nykrynova M, Barton V, Bezdicek M, Lengerova M, Skutkova H. Identification of highly variable sequence fragments in unmapped reads for rapid bacterial genotyping. BMC Genomics. 2022. https:\/\/doi.org\/10.1186\/s12864-022-08550-4.","journal-title":"BMC Genomics"}],"container-title":["BMC Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12859-023-05448-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12859-023-05448-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12859-023-05448-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T08:02:48Z","timestamp":1697616168000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcbioinformatics.biomedcentral.com\/articles\/10.1186\/s12859-023-05448-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,18]]},"references-count":5,"journal-issue":{"issue":"S2","published-online":{"date-parts":[[2023,10]]}},"alternative-id":["5448"],"URL":"https:\/\/doi.org\/10.1186\/s12859-023-05448-0","relation":{},"ISSN":["1471-2105"],"issn-type":[{"value":"1471-2105","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,18]]},"assertion":[{"value":"18 October 2023","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"361"}}