{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T21:45:34Z","timestamp":1772574334981,"version":"3.50.1"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,8,15]],"date-time":"2019-08-15T00:00:00Z","timestamp":1565827200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,8,15]],"date-time":"2019-08-15T00:00:00Z","timestamp":1565827200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008435","name":"Abramson Family Cancer Research Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008435","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006098","name":"Radiological Society of North America","doi-asserted-by":"publisher","award":["572241"],"award-info":[{"award-number":["572241"]}],"id":[{"id":"10.13039\/100006098","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Med Imaging"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1186\/s12880-019-0366-9","type":"journal-article","created":{"date-parts":[[2019,8,15]],"date-time":"2019-08-15T09:02:57Z","timestamp":1565859777000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Radiomic features from MRI distinguish myxomas from myxofibrosarcomas"],"prefix":"10.1186","volume":"19","author":[{"given":"Teresa","family":"Martin-Carreras","sequence":"first","affiliation":[]},{"given":"Hongming","family":"Li","sequence":"additional","affiliation":[]},{"given":"Kumarasen","family":"Cooper","sequence":"additional","affiliation":[]},{"given":"Yong","family":"Fan","sequence":"additional","affiliation":[]},{"given":"Ronnie","family":"Sebro","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2019,8,15]]},"reference":[{"issue":"2","key":"366_CR1","doi-asserted-by":"publisher","first-page":"374","DOI":"10.2214\/AJR.14.12888","volume":"204","author":"AD Baheti","year":"2015","unstructured":"Baheti AD, Tirumani SH, Rosenthal MH, Howard SA, Shinagare AB, Ramaiya NH, Jagannathan JP. Myxoid soft-tissue neoplasms: comprehensive update of the taxonomy and MRI features. AJR Am J Roentgenol. 2015;204(2):374\u201385. \n                    https:\/\/doi.org\/10.2214\/AJR.14.12888\n                    \n                  .","journal-title":"AJR Am J Roentgenol"},{"issue":"2","key":"366_CR2","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.cancergencyto.2007.11.008","volume":"181","author":"Neil J. Rawlinson","year":"2008","unstructured":"Rawlinson, NJ, West WW, Nelson M, Bridge, JA. Aggressive angiomyxoma with t (12;21) and HMGA2 rearrangement: Report of a case and review of the literature. Cancer Genetics and Cytogenetics. 2008; 181 (2): 119\u2013124. \n                    https:\/\/doi.org\/10.1016\/j.cancergencyto.2007.11.008\n                    \n                  . PMC 2396496. PMID 18295664.","journal-title":"Cancer Genetics and Cytogenetics"},{"issue":"11","key":"366_CR3","doi-asserted-by":"publisher","first-page":"981","DOI":"10.1002\/gcc.20483","volume":"46","author":"Fabiola Medeiros","year":"2007","unstructured":"Medeiros F, Erickson-Johnson MR, Keeney GL, Clayton AC, Nascimento AG, Wang X, Oliveira AM. Frequency and characterization of HMGA2 and HMGA1 rearrangements in mesenchymal tumours of the lower genital tract. Genes Chromosom Cancer 2007; 46 (11): 981\u2013990. \n                    https:\/\/doi.org\/10.1002\/gcc.20483\n                    \n                  . PMID 17654722.","journal-title":"Genes, Chromosomes and Cancer"},{"issue":"6","key":"366_CR4","doi-asserted-by":"publisher","first-page":"838","DOI":"10.1007\/s00428-006-0186-5","volume":"448","author":"Francesca Micci","year":"2006","unstructured":"Micci F, Panagopoulos I, Bjerkehagen B, Heim S. Deregulation of HMGA2 in an aggressive angiomyxoma with t (11;12)(q23;q15). Virchows Arch 2006; 448 (6): 838\u2013842. doi:\n                    https:\/\/doi.org\/10.1007\/s00428-006-0186-5\n                    \n                  . PMID 16568309.","journal-title":"Virchows Archiv"},{"issue":"2","key":"366_CR5","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1002\/gcc.1179","volume":"32","author":"Marisa R. Nucci","year":"2001","unstructured":"Nucci MR, Weremowicz S, Neskey DM, Sornberger K, Tallini G, Morton CC, Quade BJ. Chromosomal translocation t (8;12) induces aberrant HMGIC expression in aggressive angiomyxoma of the vulva. Genes Chromosom Cancer 2001; 32 (2): 172\u2013176. doi:\n                    https:\/\/doi.org\/10.1002\/gcc.1179\n                    \n                  . PMID 11550285.","journal-title":"Genes, Chromosomes and Cancer"},{"issue":"10","key":"366_CR6","doi-asserted-by":"publisher","first-page":"1475","DOI":"10.1007\/s00256-013-1641-4","volume":"42","author":"H Yamashita","year":"2013","unstructured":"Yamashita H, Endo K, Takeda C, Teshima R, Osaki M, Yoshida H. Intramuscular myxoma of the buttock mimicking low-grade fibromyxoid sarcoma: diagnostic usefulness of MUC4 expression. Skelet Radiol. 2013;42(10):1475\u20139. \n                    https:\/\/doi.org\/10.1007\/s00256-013-1641-4\n                    \n                   Epub 2013 May 19.","journal-title":"Skelet Radiol"},{"issue":"4","key":"366_CR7","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1016\/j.soc.2016.05.007","volume":"25","author":"AM Crago","year":"2016","unstructured":"Crago AM, Dickson MA. Liposarcoma: multimodality management and future targeted therapies. Surg Oncol Clin N Am. 2016;25(4):761\u201373.","journal-title":"Surg Oncol Clin N Am"},{"issue":"2","key":"366_CR8","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1007\/s00428-015-1778-8","volume":"467","author":"JM Cates","year":"2015","unstructured":"Cates JM, Memoli VA, Gonzalez RS. Cell cycle and apoptosis regulatory proteins, proliferative markers, cell signaling molecules, CD209, and decorin immunoreactivity in low-grade myxofibrosarcoma and myxoma. Virchows Arch. 2015;467(2):211\u20136. \n                    https:\/\/doi.org\/10.1007\/s00428-015-1778-8\n                    \n                   Epub 2015 May 5.","journal-title":"Virchows Arch"},{"issue":"3","key":"366_CR9","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1002\/dc.2840110312","volume":"11","author":"NP Caraway","year":"1994","unstructured":"Caraway NP, Staerkel GA, Fanning CV, Varma DG, Pollock RE. Diagnosing intramuscular myxoma by fine-needle aspiration: a multidisciplinary approach. Diagn Cytopathol. 1994;11(3):255\u201361.","journal-title":"Diagn Cytopathol"},{"issue":"2","key":"366_CR10","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1055\/s-2000-19248","volume":"32","author":"I Schlenz","year":"2000","unstructured":"Schlenz I, Kuzbari R, Holle J, Worseg A. Soft tissue tumours with difficult to distinguish boundaries. From myxoma to myxofibrosarcoma: a case report. Handchir Mikrochir Plast Chir. 2000;32(2):138\u201342.","journal-title":"Handchir Mikrochir Plast Chir"},{"issue":"4","key":"366_CR11","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1097\/00000478-199604000-00001","volume":"20","author":"T Mentzel","year":"1996","unstructured":"Mentzel T, Calonje E, Wadden C, Camplejohn RS, Beham A, Smith MA, Fletcher CD. Myxofibrosarcoma. Clinicopathologic analysis of 75 cases with emphasis on the low-grade variant. Am J Surg Pathol. 1996;20(4):391\u2013405.","journal-title":"Am J Surg Pathol"},{"issue":"Suppl 3","key":"366_CR12","doi-asserted-by":"publisher","first-page":"iii102","DOI":"10.1093\/annonc\/mdu254","volume":"25","author":"The ESMO\/European Sarcoma Network Working Group","year":"2014","unstructured":"The ESMO\/European Sarcoma Network Working Group. Soft tissue and visceral sarcomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2014;25(Suppl 3):iii102\u201312.","journal-title":"Ann Oncol"},{"issue":"11","key":"366_CR13","doi-asserted-by":"publisher","first-page":"2992","DOI":"10.1007\/s11999-010-1401-x","volume":"468","author":"S Kasraeian","year":"2010","unstructured":"Kasraeian S, Allison DC, Ahlmann ER, Fedenko AN, Menendez LR. A comparison of fine-needle aspiration, core biopsy, and surgical biopsy in the diagnosis of extremity soft tissue masses. Clin Orthop Relat Res. 2010;468(11):2992\u20133002.","journal-title":"Clin Orthop Relat Res"},{"issue":"5","key":"366_CR14","doi-asserted-by":"publisher","first-page":"1255","DOI":"10.2214\/ajr.178.5.1781255","volume":"178","author":"LW Bancroft","year":"2002","unstructured":"Bancroft LW, Kransdorf MJ, Menke DM, O'Connor MI, Foster WC. Intramuscular myxoma: characteristic MR imaging features. AJR Am J Roentgenol. 2002;178(5):1255\u20139.","journal-title":"AJR Am J Roentgenol"},{"issue":"1","key":"366_CR15","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1148\/radiol.2251011627","volume":"225","author":"MD Murphey","year":"2002","unstructured":"Murphey MD, McRae GA, Fanburg-Smith JC, Temple HT, Levine AM, Aboulafia AJ. Imaging of soft-tissue myxoma with emphasis on CT and MR and comparison of radiologic and pathologic findings. Radiology. 2002;225(1):215\u201324.","journal-title":"Radiology."},{"issue":"774","key":"366_CR16","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1259\/0007-1285-65-774-485","volume":"65","author":"IF Abdelwahab","year":"1992","unstructured":"Abdelwahab IF, Kenan S, Hermann G, Lewis MM, Klein MJ. Intramuscular myxoma: magnetic resonance features. Br J Radiol. 1992;65(774):485\u201390.","journal-title":"Br J Radiol"},{"key":"366_CR17","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1186\/1477-7819-10-132","volume":"10","author":"J Nishio","year":"2012","unstructured":"Nishio J, Naito M. FDG PET\/CT and MR imaging of intramuscular myxoma in the gluteus maximus. World J Surg Oncol. 2012;10:132. \n                    https:\/\/doi.org\/10.1186\/1477-7819-10-132\n                    \n                  .","journal-title":"World J Surg Oncol"},{"issue":"12","key":"366_CR18","doi-asserted-by":"publisher","first-page":"1085","DOI":"10.1007\/s00256-008-0542-4","volume":"37","author":"M Kaya","year":"2008","unstructured":"Kaya M, Wada T, Nagoya S, Sasaki M, Matsumura T, Yamaguchi T, Hasegawa T, Yamashita T. MRI and histological evaluation of the infiltrative growth pattern of myxofibrosarcoma. Skelet Radiol. 2008;37(12):1085\u201390. \n                    https:\/\/doi.org\/10.1007\/s00256-008-0542-4\n                    \n                   Epub 2008 Jul 16.","journal-title":"Skelet Radiol"},{"issue":"4","key":"366_CR19","doi-asserted-by":"publisher","first-page":"964","DOI":"10.1148\/rg.344130110","volume":"34","author":"JM Petscavage-Thomas","year":"2014","unstructured":"Petscavage-Thomas JM, Walker EA, Logie CI, Clarke LE, Duryea DM, Murphey MD. Soft-tissue myxomatous lesions: review of salient imaging features with pathologic comparison. Radiographics. 2014;34(4):964\u201380. \n                    https:\/\/doi.org\/10.1148\/rg.344130110\n                    \n                  .","journal-title":"Radiographics."},{"key":"366_CR20","unstructured":"R Core Team 2015. R: a language and environment for statistical computing. 3rd ed. Vienna, Austria: R Foundation for Statistical Computing; 2015. \n                    http:\/\/www.R-project.org\/\n                    \n                  ."},{"issue":"6","key":"366_CR21","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1007\/s00256-012-1563-6","volume":"42","author":"RA Lefkowitz","year":"2013","unstructured":"Lefkowitz RA, Landa J, Hwang S, Zabor EC, Moskowitz CS, Agaram NP, Panicek DM. Myxofibrosarcoma: prevalence and diagnostic value of the \"tail sign\" on magnetic resonance imaging. Skelet Radiol. 2013;42(6):809\u201318. \n                    https:\/\/doi.org\/10.1007\/s00256-012-1563-6\n                    \n                   Epub 2013 Jan 15.","journal-title":"Skelet Radiol"},{"issue":"1","key":"366_CR22","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.crad.2016.09.013","volume":"72","author":"E Sala","year":"2017","unstructured":"Sala E, Mema E, Himoto Y, Veeraraghavan H, Brenton JD, Snyder A, Weigelt B, Vargas HA. Unravelling tumour heterogeneity using next-generation imaging: radiomics, radiogenomics, and habitat imaging. Clin Radiol. 2017;72(1):3\u201310.","journal-title":"Clin Radiol"},{"issue":"7","key":"366_CR23","doi-asserted-by":"publisher","first-page":"2041","DOI":"10.1007\/s00330-014-3576-0","volume":"25","author":"IM Noebauer-Huhmann","year":"2015","unstructured":"Noebauer-Huhmann IM, Amann G, Krssak M, Panotopoulos J, Szomolanyi P, Weber M, Czerny C, Breitenseher M, Grabner G, Bogner W, Nemec S, Dominkus M, Funovics P, Windhager R, Trattnig S. Use of diagnostic dynamic contrast-enhanced (DCE)-MRI for targeting of soft tissue tumour biopsies at 3T: preliminary results. Eur Radiol. 2015;25(7):2041\u20138. \n                    https:\/\/doi.org\/10.1007\/s00330-014-3576-0\n                    \n                   Epub 2015 Jan 11.","journal-title":"Eur Radiol"},{"issue":"23","key":"366_CR24","doi-asserted-by":"publisher","first-page":"5765","DOI":"10.1158\/1078-0432.CCR-16-0702","volume":"22","author":"P Kickingereder","year":"2016","unstructured":"Kickingereder P, G\u00f6tz M, Muschelli J, Wick A, Neuberger U, Shinohara RT, Sill M, Nowosielski M, Schlemmer HP, Radbruch A, Wick W, Bendszus M, Maier-Hein KH, Bonekamp D. Large-scale Radiomic profiling of recurrent glioblastoma identifies an imaging predictor for stratifying anti-Angiogenic treatment response. Clin Cancer Res. 2016;22(23):5765\u201371.","journal-title":"Clin Cancer Res"},{"issue":"4","key":"366_CR25","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1007\/s11548-017-1691-5","volume":"13","author":"B Shofty","year":"2018","unstructured":"Shofty B, Artzi M, Ben bashat D, Liberman G, Haim O, Kashanian A, Bokstein F, Blumenthal DT, Ram Z, Shahar T. MRI radiomics analysis of molecular alterations in low-grade gliomas. Int J Comput Assist Radiol Surg. 2018;13(4):563\u201371.","journal-title":"Int J Comput Assist Radiol Surg"},{"issue":"3","key":"366_CR26","doi-asserted-by":"publisher","first-page":"223","DOI":"10.18383\/j.tom.2016.00250","volume":"2","author":"SD Mcgarry","year":"2016","unstructured":"Mcgarry SD, Hurrell SL, Kaczmarowski AL, Cochran EJ, Connelly J, Rand SD, Schmainda KM, LaViolette PS. Magnetic resonance imaging-based Radiomic profiles predict patient prognosis in newly diagnosed glioblastoma before therapy. Tomography. 2016;2(3):223\u20138.","journal-title":"Tomography."},{"issue":"2","key":"366_CR27","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1016\/j.radonc.2018.06.025","volume":"129","author":"Hongming Li","year":"2018","unstructured":"Li H, Galperin-Aizenberg M, Pryma D, Simone CB, Fan Y. Unsupervised machine learning of radiomic features for predicting treatment response and overall survival of early stage non-small cell lung cancer patients treated with stereotactic body radiation therapy. Radiother Oncol. 2018;129(2):218-26.","journal-title":"Radiotherapy and Oncology"},{"key":"366_CR28","doi-asserted-by":"publisher","unstructured":"Li H, Boimel P, Janopaul-Naylor J, Zhong H, Xiao Y, Ben-Josef E, Fan Y. Deep convolutional neural networks for imaging data based survival analysis of rectal cancer, 2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI 2019), Venice, Italy, 2019, pp. 846-849. \n                    https:\/\/doi.org\/10.1109\/ISBI.2019.8759301\n                    \n                  .","DOI":"10.1109\/ISBI.2019.8759301"},{"key":"366_CR29","doi-asserted-by":"crossref","unstructured":"Men K, Geng H, Zhong H, Fan Y, Lin A, Xiao Y. A deep learning model for predicting xerostomia due to radiation therapy for head and neck squamous cell carcinoma in the RTOG 0522 Clinical Trial. Int J Radiat Oncol Biol Phys. 2019. In press.","DOI":"10.1016\/j.ijrobp.2019.06.009"}],"container-title":["BMC Medical Imaging"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12880-019-0366-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12880-019-0366-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12880-019-0366-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,13]],"date-time":"2020-08-13T23:12:10Z","timestamp":1597360330000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcmedimaging.biomedcentral.com\/articles\/10.1186\/s12880-019-0366-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,15]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["366"],"URL":"https:\/\/doi.org\/10.1186\/s12880-019-0366-9","relation":{},"ISSN":["1471-2342"],"issn-type":[{"value":"1471-2342","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,15]]},"assertion":[{"value":"7 January 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 August 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 August 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The study was reviewed and approved by the senior authors\u2019 institutional review board and approved for publication. The need for signed informed consent was waived by the IRB because the results presented do not disclose personal health information (PHI).","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"67"}}