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Preoperative T1 mapping and DWI on gadoxetic acid-enhanced MRI was performed. The parameters including precontrast, postcontrast and reduction rate of T1 relaxation time and apparent diffusion coefficient (ADC) values were measured for differentiating MVI-positive HCCs (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200938) from MVI-negative HCCs (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200956). The receiver operating characteristic curve (ROC) was analyzed to compare the diagnostic performance of the calculated parameters.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      MVI-positive HCCs demonstrated a significantly lower reduction rate of T1 relaxation time than that of MVI-negative HCCs (39.4% vs 49.9,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001). The areas under receiver operating characteristic curve (AUC) were 0.587, 0.728, 0.824, 0,690 and 0.862 for the precontrast, postcontrast, reduction rate of T1 relaxation time, ADC and the combination of reduction rate and ADC, respectively. The cut-off value of the reduction rate and ADC calculated through maximal Youden index in ROC analyses was 44.9% and 1553.5\u2009s\/mm\n                      <jats:sup>2<\/jats:sup>\n                      . To achieve a better diagnostic performance, the criteria of combining the reduction rate lower than 44.9% and the ADC value lower than 1553.5\u2009s\/mm\n                      <jats:sup>2<\/jats:sup>\n                      was proposed with a high specificity of 91.8% and accuracy of 80.9%.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      The proposed criteria of combining the reduction rate of T1 relaxation time lower than 44.9% and the ADC value lower than 1553.5\u2009s\/mm\n                      <jats:sup>2<\/jats:sup>\n                      on gadoxetic acid-enhanced MRI holds promise for evaluating MVI status of HCC.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12880-020-00433-y","type":"journal-article","created":{"date-parts":[[2020,4,28]],"date-time":"2020-04-28T08:03:54Z","timestamp":1588061034000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Value of T1 mapping on gadoxetic acid-enhanced MRI for microvascular invasion of hepatocellular carcinoma: a retrospective study"],"prefix":"10.1186","volume":"20","author":[{"given":"Chenyi","family":"Rao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinquan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minda","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guofeng","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongmei","family":"Gu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,4,28]]},"reference":[{"issue":"6","key":"433_CR1","doi-asserted-by":"publisher","first-page":"394","DOI":"10.3322\/caac.21492","volume":"68","author":"F Bray","year":"2018","unstructured":"Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. 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