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The dataset was used to extract CT-radiomics features from regions of interest (ROI), The intra-class correlation coefficient (ICC) was used to screen the robust feature from all the radiomic features. Using, then, statistical methods to screen CT-radiomics features, which could distinguish peripheral lung cancer and PIPT. And the ability of radiomics features distinguished peripheral lung cancer and PIPT was estimated by receiver operating characteristic (ROC) curve and compared by the Delong test.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 435 radiomics features were extracted, of which 361 features showed relatively good repeatability (ICC\u2009\u2265\u20090.6). 20 features showed the ability to distinguish peripheral lung cancer from PIPT. these features were seen in 14 of 330 Gray-Level Co-occurrence Matrix features, 1 of 49 Intensity Histogram features, 5 of 18 Shape features. The area under the curves (AUC) of these features were 0.731 \u00b1 0.075, 0.717, 0.748 \u00b1 0.038, respectively. The\n                      <jats:italic>P<\/jats:italic>\n                      values of statistical differences among ROC were 0.0499 (F9, F20), 0.0472 (F10, F11) and 0.0145 (F11, Mean4). The discrimination ability of forming new features (Parent Features) after averaging the features extracted at different angles and distances was moderate compared to the previous features (Child features).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Radiomics features extracted from non-contrast CT based on PET\/CT images can help distinguish peripheral lung cancer and PIPT.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12880-020-00475-2","type":"journal-article","created":{"date-parts":[[2020,7,6]],"date-time":"2020-07-06T08:03:44Z","timestamp":1594022624000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Using CT texture analysis to differentiate between peripheral lung cancer and pulmonary inflammatory pseudotumor"],"prefix":"10.1186","volume":"20","author":[{"given":"Chenlu","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changsheng","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinghao","family":"Duan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingtao","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanluan","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhenhua","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,7,6]]},"reference":[{"issue":"1, Supplement","key":"475_CR1","doi-asserted-by":"crossref","first-page":"21S","DOI":"10.1378\/chest.123.1_suppl.21S","volume":"123","author":"AJ Alberg","year":"2003","unstructured":"Alberg AJ, Samet JM. 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After a vote (Total 11, Agree 11, Disagree 0), the IRB agreed that the study followed the guidelines of good clinical practice (GCP) and that the trial could be conducted at Shandong Cancer Hospital and Institute (NO. 201905047).","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"75"}}