{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T20:55:11Z","timestamp":1769720111563,"version":"3.49.0"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2020,9,16]],"date-time":"2020-09-16T00:00:00Z","timestamp":1600214400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,9,16]],"date-time":"2020-09-16T00:00:00Z","timestamp":1600214400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Tianjin Medical University Natural Science Funds","award":["2016KYZM02"],"award-info":[{"award-number":["2016KYZM02"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Med Imaging"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>We compared the ultrasound features, superb microvascular imaging (SMI) and micro vessel density (MVD) of pleomorphic adenoma (PA), Warthin\u2019s tumor (WT) and basal cell adenoma (BCA) to explore the clinic value of SMI in differential diagnosis of benign tumors of parotid gland.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>The vascular distributions and grade by color doppler flow imaging (CDFI) and SMI, as well as vascular index (VI) of 249 parotid gland masses from 217 patients were analyzed.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The internal echogenicity of BCA are more homogeneous in comparing with WT and PA(<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). By SMI, the vascular distribution and vascular grade in PA were mainly peripheral (33.1%) and avascular (25.7%), Grade 1 (27.8%) and Grade 0 (25.7%). WT were mainly central (31.3%) and mixed distribution (34.9%), in Grade 3 (37.3%) and Grade 2 (36.2%). BCA was mainly peripheral (33.3%) and mixed distribution (33.3%), in Grade 2 (33.3%) and Grade 3 (33.3%). The overall detection rate of SMI for vascular Grade 2 and 3 was significantly higher than that of CDFI (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). Both VI and MVD were lowest in PA, highest in WT (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). The VI by SMI was correlated with MVD (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). The correlation index between vascular distribution and grade by SMI and MVD were significantly higher than CDFI.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>SMI can provide low-velocity blood flow information, which is helpful for the differential diagnosis of common benign tumors of parotid gland, and is expected to be more widely used.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12880-020-00506-y","type":"journal-article","created":{"date-parts":[[2020,9,16]],"date-time":"2020-09-16T11:05:01Z","timestamp":1600254301000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["The diagnostic value of Superb Microvascular Imaging in identifying benign tumors of parotid gland"],"prefix":"10.1186","volume":"20","author":[{"given":"Lihui","family":"Zhao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yiran","family":"Mao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Mu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fangxuan","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2277-9855","authenticated-orcid":false,"given":"Sheng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaojie","family":"Xin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,9,16]]},"reference":[{"issue":"S4","key":"506_CR1","doi-asserted-by":"crossref","first-page":"S144","DOI":"10.1002\/lary.22021","volume":"121","author":"MD HelenPerakis","year":"2011","unstructured":"HelenPerakis MD, Albert D'Heurle BS, Brandon Miller BS, et al. Usefulness of CT and MRI in predicting parotid gland tumor histopathology. Laryngoscope. 2011;121(S4):S144.","journal-title":"Laryngoscope"},{"issue":"5","key":"506_CR2","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1007\/s00405-009-1139-9","volume":"267","author":"R Kawata","year":"2010","unstructured":"Kawata R, Yoshimura K, Lee K, et al. Basal cell adenoma of the parotid gland: a clinicopathological study of nine cases--basal cell adenoma versus pleomorphic adenoma and Warthin\u2019s tumor. Eur Arch Otorhinolaryngol. 2010;267(5):779\u201383.","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"506_CR3","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0929-8266(00)00096-3","volume":"12","author":"P Zajkowski","year":"2000","unstructured":"Zajkowski P, Jakubowski W, Bialek EJ, et al. Pleomorphic adenoma and adenolymphoma in ultrasonography. 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Written consents were obtained from each adult patient or children\u2019s (age under 16\u2009years old) parents.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written consents were obtained from each adult patient or children\u2019s (age under 16\u2009years old) parents to publishing their pathological images as represent Figures.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors have declared that no competing interests exist.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"107"}}