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They were divided into a TLE with depression group (n\u2009=\u200911) and a TLE without depression group (n\u2009=\u200913), according to the results of the HAMD-24 Scale. Two groups patients were examined using <jats:sup>18<\/jats:sup>F-FDG PET brain imaging.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The low metabolic regions of the TLE with depression group were mainly found in the left frontal lobe, temporal lobe and fusiform gyrus, while the high metabolic regions of the TLE with depression group were mainly located in the right frontal lobe, visual joint cortex and superior posterior cingulate cortex. Both of the TLE groups had high metabolic compensation in the non-epileptic area during the interictal period.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>There is an uptake difference of <jats:sup>18<\/jats:sup>F-FDG between TLE patients with depression and TLE patients without depression in multiple encephalic regions.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12880-021-00547-x","type":"journal-article","created":{"date-parts":[[2021,2,22]],"date-time":"2021-02-22T09:04:07Z","timestamp":1613984647000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["A PET imaging study of the brain changes of glucose metabolism in patients with temporal lobe epilepsy and depressive disorder"],"prefix":"10.1186","volume":"21","author":[{"given":"Jin-Feng","family":"Wen","sequence":"first","affiliation":[]},{"given":"Xin-Wen","family":"Guo","sequence":"additional","affiliation":[]},{"given":"Xiang-Yi","family":"Cao","sequence":"additional","affiliation":[]},{"given":"Ji-Wu","family":"Liao","sequence":"additional","affiliation":[]},{"given":"Ping","family":"Ma","sequence":"additional","affiliation":[]},{"given":"Xiang-Shu","family":"Hu","sequence":"additional","affiliation":[]},{"given":"Ji-Yang","family":"Pan","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2021,2,22]]},"reference":[{"key":"547_CR1","doi-asserted-by":"publisher","first-page":"106412","DOI":"10.1016\/j.eplepsyres.2020.106412","volume":"166","author":"Y Zhang","year":"2020","unstructured":"Zhang Y, Liu Y, Jia Y, Zhao Y, Ma C, Bao X, et al. 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