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However, this procedure is less commonly used in comparison to US guided transcutaneous biopsy. The aim of this study is to compare the efficacy and safety of US-guided transoral and transcutaneous core needle biopsy (CNB) in patients with oral masses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>From November 2019 to March 2021, consecutive patients with oral masses were randomly assigned to undergo US-guided transoral CNB (transoral group) and US-guided transcutaneous CNB from a submental approach (transcutaneous group). During the operation, procedure time, intra\u2011operative blood loss volume, diagnostic performance, rate of complications and pain level were recorded and compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There were 112 patients (62 in the transoral group and 50 in the transcutaneous group) evaluated in this study. The postprocedural complication rate of the transcutaneous group was significantly higher than the transoral group (24% vs. 0%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.000). There was no significant difference in accuracy (95.2% vs. 88%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.30), biopsy time (76\u2009\u00b1\u200912\u00a0s vs. 80\u2009\u00b1\u200913\u00a0s,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.09), blood losses (2.6\u2009\u00b1\u20090.5\u00a0mL vs. 2.7\u2009\u00b1\u20090.4\u00a0mL,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.17) and visual analogue score (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.327 and\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.444 before and after the sampling procedure) between the two groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>US-guided transoral CNB results in high rates of technical success and lower rates of postprocedural complications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12880-022-00784-8","type":"journal-article","created":{"date-parts":[[2022,4,7]],"date-time":"2022-04-07T00:12:33Z","timestamp":1649290353000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Comparative study on efficacy and safety of ultrasound guided transoral and transcutaneous core needle biopsy in patients with oral masses"],"prefix":"10.1186","volume":"22","author":[{"given":"Ting","family":"Wei","sequence":"first","affiliation":[]},{"given":"Man","family":"Lu","sequence":"additional","affiliation":[]},{"given":"Juan","family":"Li","sequence":"additional","affiliation":[]},{"given":"Ziyue","family":"Hu","sequence":"additional","affiliation":[]},{"given":"Tingting","family":"Li","sequence":"additional","affiliation":[]},{"given":"Xueqing","family":"Cheng","sequence":"additional","affiliation":[]},{"given":"Lu","family":"Wang","sequence":"additional","affiliation":[]},{"given":"Wei","family":"Pu","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2022,4,7]]},"reference":[{"issue":"9","key":"784_CR1","doi-asserted-by":"publisher","first-page":"1083","DOI":"10.1080\/0284186X.2021.1931712","volume":"60","author":"BB Lauritzen","year":"2021","unstructured":"Lauritzen BB, Jensen JS, Gr\u00f8nh\u00f8j C, Wessel I, von Buchwald C. 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E.g., the Declaration of Helsinki. This prospective study was approved by the Ethics Committee of Sichuan Cancer Hospital (Chengdu, China), and written informed consent was obtained from all participants.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"65"}}