{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T22:11:29Z","timestamp":1774044689558,"version":"3.50.1"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T00:00:00Z","timestamp":1652659200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T00:00:00Z","timestamp":1652659200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100010270","name":"Capital Health Research and Development of Special Fund","doi-asserted-by":"publisher","award":["2020-2-4063"],"award-info":[{"award-number":["2020-2-4063"]}],"id":[{"id":"10.13039\/501100010270","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010270","name":"Capital Health Research and Development of Special Fund","doi-asserted-by":"publisher","award":["2020-2-4063"],"award-info":[{"award-number":["2020-2-4063"]}],"id":[{"id":"10.13039\/501100010270","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010270","name":"Capital Health Research and Development of Special Fund","doi-asserted-by":"publisher","award":["2020-2-4063"],"award-info":[{"award-number":["2020-2-4063"]}],"id":[{"id":"10.13039\/501100010270","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010270","name":"Capital Health Research and Development of Special Fund","doi-asserted-by":"publisher","award":["2020-2-4063"],"award-info":[{"award-number":["2020-2-4063"]}],"id":[{"id":"10.13039\/501100010270","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010270","name":"Capital Health Research and Development of Special Fund","doi-asserted-by":"publisher","award":["2020-2-4063"],"award-info":[{"award-number":["2020-2-4063"]}],"id":[{"id":"10.13039\/501100010270","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010270","name":"Capital Health Research and Development of Special Fund","doi-asserted-by":"publisher","award":["2020-2-4063"],"award-info":[{"award-number":["2020-2-4063"]}],"id":[{"id":"10.13039\/501100010270","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Natural Key Clinical Specialty Construction Project","award":["2020-QTL-009"],"award-info":[{"award-number":["2020-QTL-009"]}]},{"name":"National Natural Key Clinical Specialty Construction Project","award":["2020-QTL-009"],"award-info":[{"award-number":["2020-QTL-009"]}]},{"name":"National Natural Key Clinical Specialty Construction Project","award":["2020-QTL-009"],"award-info":[{"award-number":["2020-QTL-009"]}]},{"name":"National Natural Key Clinical Specialty Construction Project","award":["2020-QTL-009"],"award-info":[{"award-number":["2020-QTL-009"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Med Imaging"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Noninvasive assessment of pulmonary artery systolic pressure by Doppler echocardiography (sPAP<jats:sub>ECHO<\/jats:sub>) has been widely adopted to screen for pulmonary hypertension (PH), but there is still a high proportion of overestimation or underestimation of sPAP<jats:sub>ECHO<\/jats:sub>. We therefore aimed to explore the accuracy and influencing factors of sPAP<jats:sub>ECHO<\/jats:sub> with right heart catheterization (RHC) as a reference.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>A total of 218 highly suspected PH patients who underwent RHC and echocardiography within 7\u00a0days were included. The correlation and consistency between tricuspid regurgitation (TR)-related methods and RHC results were tested by Pearson and Bland\u2013Altman methods. TR-related methods included peak velocity of TR (TR Vmax), TR pressure gradient (TR-PG), TR mean pressure gradient (TR-mPG), estimated mean pulmonary artery pressure (mPAP<jats:sub>ECHO<\/jats:sub>), and sPAP<jats:sub>ECHO<\/jats:sub>. With mPAP\u2009\u2265\u200925\u00a0mm Hg measured by RHC as the standard diagnostic criterion of PH, the ROC curve was used to compare the diagnostic efficacy of sPAP<jats:sub>ECHO<\/jats:sub> with other TR-derived parameters. The ratio (sPAP<jats:sub>ECHO<\/jats:sub>\u2013sPAP<jats:sub>RHC<\/jats:sub>)\/sPAP<jats:sub>RHC<\/jats:sub> was calculated and divided into three groups as follows: patients with an estimation error between\u2009\u2212\u200910% and\u2009+\u200910% were defined as the accurate group; patients with an estimated difference greater than\u2009+\u200910% were classified as the overestimated group; and patients with an estimation error greater than\u2009\u2212\u200910% were classified as the underestimated group. The influencing factors of sPAP<jats:sub>ECHO<\/jats:sub> were analyzed by ordinal regression analysis.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>sPAP<jats:sub>ECHO<\/jats:sub> had the highest correlation coefficient (r\u2009=\u20090.781, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), best diagnostic efficiency (AUC\u2009=\u20090.98), and lowest bias (mean bias\u2009=\u20090.07\u00a0mm Hg; 95% limits of agreement,\u2009\u2212\u200932.08 to\u2009+\u200932.22\u00a0mm Hg) compared with other TR-related methods. Ordinal regression analysis showed that TR signal quality, sPAP<jats:sub>RHC<\/jats:sub> level, and pulmonary artery wedge pressure (PAWP) affected the accuracy of sPAP<jats:sub>ECHO<\/jats:sub> (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). Relative to the good signal quality, the OR values of medium and poor signal quality were 0.26 (95% CI: 0.14, 0.48) and 0.23 (95% CI: 0.07, 0.73), respectively. Compared with high sPAP<jats:sub>RHC<\/jats:sub> level, the OR values of low and medium sPAP<jats:sub>RHC<\/jats:sub> levels were 21.56 (95% CI: 9.57, 48.55) and 5.13 (95% CI: 2.55, 10.32), respectively. The OR value of PAWP was 0.94 (95% CI: 0.89, 0.99). TR severity and right ventricular systolic function had no significant effect on the accuracy of sPAP<jats:sub>ECHO<\/jats:sub>.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>In this study, we found that all TR-related methods, including sPAP<jats:sub>ECHO<\/jats:sub>, had comparable and good efficiency in PH screening. To make the assessment of sPAP<jats:sub>ECHO<\/jats:sub> more accurate, attention should be paid to TR signal quality, sPAP<jats:sub>RHC<\/jats:sub> level, and PAWP.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12880-022-00806-5","type":"journal-article","created":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T11:05:41Z","timestamp":1652699141000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["The accuracy and influencing factors of Doppler echocardiography in estimating pulmonary artery systolic pressure: comparison with right heart catheterization: a retrospective cross-sectional study"],"prefix":"10.1186","volume":"22","author":[{"given":"Guang-jie","family":"Lv","sequence":"first","affiliation":[]},{"given":"Ai-li","family":"Li","sequence":"additional","affiliation":[]},{"given":"Xin-cao","family":"Tao","sequence":"additional","affiliation":[]},{"given":"Ya-nan","family":"Zhai","sequence":"additional","affiliation":[]},{"given":"Yu","family":"Zhang","sequence":"additional","affiliation":[]},{"given":"Jie-ping","family":"Lei","sequence":"additional","affiliation":[]},{"given":"Qian","family":"Gao","sequence":"additional","affiliation":[]},{"given":"Wan-mu","family":"Xie","sequence":"additional","affiliation":[]},{"given":"Zhen-guo","family":"Zhai","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2022,5,16]]},"reference":[{"issue":"4","key":"806_CR1","doi-asserted-by":"publisher","first-page":"903","DOI":"10.1183\/13993003.01032-2015","volume":"46","author":"N Galie","year":"2015","unstructured":"Galie N, Humbert M, Vachiery JL, et al. 2015 ESC\/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT). 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Ethical approval number was 2020-95-K59. The protocol was approved by the Ethic Committee of China-Japan Friendship Hospital. The institutional review board of the China-Japan Friendship Hospital waived the need for written patient informed consent as this study involved the retrospective analysis of clinically acquired data.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"91"}}