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The differences in quantitative DCE-MRI and DWI parameters including Krans, Kep and ADC values were analyzed between MR-detected EMVI (mrEMVI)-positive and -negative groups. Multivariate logistic regression analysis was performed to build the combined prediction model for pathologic EMVI (pEMVI) with statistically significant quantitative parameters. The performance of the model for predicting pEMVI was evaluated using receiver operating characteristic (ROC) curve.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Of the 82 patients, 24 were mrEMVI-positive and 58 were -negative. In the mrEMVI positive group, the Ktrans and Kep values were significantly higher than those in the mrEMVI negative group (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01), but the ADC values were significantly lower (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). A negative correlation was observed between the Ktrans vs ADC values and Kep vs ADC values in patients with rectal cancer. Among the four quantitative parameters, Ktrans and ADC value were independently associated with mrEMVI by multivariate logistic regression analysis. ROC analysis showed that combined prediction model based on quantitative DCE parameters and ADC values had a good prediction efficiency for pEMVI in rectal cancer.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The quantitative DCE-MRI parameters, Krans, Kep and ADC values play important role in predicting EMVI of rectal cancer, with Ktrans and ADC value being independent predictors of EMVI in rectal cancer.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12880-022-00810-9","type":"journal-article","created":{"date-parts":[[2022,4,28]],"date-time":"2022-04-28T12:04:24Z","timestamp":1651147464000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Preoperative prediction of extramural venous invasion in rectal cancer by dynamic contrast-enhanced and diffusion weighted MRI: a preliminary study"],"prefix":"10.1186","volume":"22","author":[{"given":"Weiqun","family":"Ao","sequence":"first","affiliation":[]},{"given":"Xian","family":"Zhang","sequence":"additional","affiliation":[]},{"given":"Xiuzhen","family":"Yao","sequence":"additional","affiliation":[]},{"given":"Xiandi","family":"Zhu","sequence":"additional","affiliation":[]},{"given":"Shuitang","family":"Deng","sequence":"additional","affiliation":[]},{"given":"Jianju","family":"Feng","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2022,4,28]]},"reference":[{"key":"810_CR1","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1016\/j.surge.2020.11.014","volume":"19","author":"M Baig","year":"2021","unstructured":"Baig M, Sayyed R, Nasim S, Khan S. 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