{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T10:58:49Z","timestamp":1740135529308,"version":"3.37.3"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,7,14]],"date-time":"2022-07-14T00:00:00Z","timestamp":1657756800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,7,14]],"date-time":"2022-07-14T00:00:00Z","timestamp":1657756800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Med Imaging"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Malignant \u2018triton\u2019 tumor is an extremely rare subtype of malignant periphery nerve sheath tumors. Clinical diagnosis of malignant triton tumor is difficult before surgery due to its low incidence and the lack of knowledge. Therefore, to describe and summarize the CT imaging characteristics of malignant triton tumor is of great assistance for early and preoperative diagnosis.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>Two cases suspected of MTT by CT scan before operation were closely observed. The diagnosis of malignant triton tumor was eventually confirmed by immunochemical assay, which verified speculation of CT scans. Huge, irregular, well-circumscribed lobulated mass-like shadows can be observed from these patients by CT scans. Besides, heterogeneity of density within the body of tumor was well-established by CT scans, together with linear septum. Meanwhile, CT scans demonstrated that calcifications were remarkable at the margin of tumor body.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Some CT image features from two cases were presented as a reference for the preoperative consideration of MTT: (i) enormity of mass-like shadow; (ii) presence of well-circumscribed lobulated shape; (iii) septum within the well-defined mass accompanied with hemorrhage, necrosis and cystic changes as well as calcification, especially within neurofibromatosis type 1 patients.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12880-022-00848-9","type":"journal-article","created":{"date-parts":[[2022,7,14]],"date-time":"2022-07-14T12:05:14Z","timestamp":1657800314000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Computed tomography imaging features of malignant \u2018triton\u2019 tumor to facilitate its clinical diagnosis: report of two cases"],"prefix":"10.1186","volume":"22","author":[{"given":"Yuan","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiling","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ning","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David P.","family":"Molloy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chun","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7807-8882","authenticated-orcid":false,"given":"Qingchen","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,7,14]]},"reference":[{"issue":"1","key":"848_CR1","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1097\/JTO.0b013e31819151ab","volume":"4","author":"J Dartnell","year":"2009","unstructured":"Dartnell J, Pilling J, Ferner R, Cane P, Lang-Lazdunski L. Malignant triton tumor of the brachial plexus invading the left thoracic inlet: a rare differential diagnosis of pancoast tumor. J Thorac Oncol. 2009;4(1):135\u20137.","journal-title":"J Thorac Oncol"},{"issue":"4","key":"848_CR2","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1007\/s12105-015-0624-2","volume":"9","author":"JA Bishop","year":"2015","unstructured":"Bishop JA, Thompson LD, Cardesa A, Barnes L, Lewis JJ, Triantafyllou A, Hellquist H, Stenman G, Hunt JL, Williams MD, et al. Rhabdomyoblastic differentiation in head and neck malignancies other than rhabdomyosarcoma. Head Neck Pathol. 2015;9(4):507\u201318.","journal-title":"Head Neck Pathol"},{"issue":"12","key":"848_CR3","doi-asserted-by":"publisher","first-page":"1878","DOI":"10.5858\/2006-130-1878-MPNSTW","volume":"130","author":"CJ Stasik","year":"2006","unstructured":"Stasik CJ, Tawfik O. Malignant peripheral nerve sheath tumor with rhabdomyosarcomatous differentiation (malignant triton tumor). Arch Pathol Lab Med. 2006;130(12):1878\u201381.","journal-title":"Arch Pathol Lab Med"},{"issue":"11","key":"848_CR4","first-page":"2543","volume":"55","author":"JS Brooks","year":"1985","unstructured":"Brooks JS, Freeman M, Enterline HT. Malignant \u201cTriton\u201d tumors. Natural history and immunohistochemistry of nine new cases with literature review. Cancer-Am Cancer Soc. 1985;55(11):2543\u20139.","journal-title":"Cancer-Am Cancer Soc"},{"issue":"3","key":"848_CR5","first-page":"277","volume":"17","author":"E Kamperis","year":"2013","unstructured":"Kamperis E, Barbetakis N, Asteriou C, Kleontas A, Christoforidou V. Malignant triton tumor of the chest wall invading the lung A case report and literature review. Hippokratia. 2013;17(3):277\u201380.","journal-title":"Hippokratia"},{"issue":"6","key":"848_CR6","doi-asserted-by":"publisher","first-page":"3551","DOI":"10.3892\/ol.2015.3762","volume":"10","author":"G Li","year":"2015","unstructured":"Li G, Liu C, Liu Y, Xu F, Su Z, Wang Y, Ren S, Deng T, Huang D, Tian Y, et al. Analysis of clinical features and prognosis of malignant triton tumor: A report of two cases and literature review. Oncol Lett. 2015;10(6):3551\u20136.","journal-title":"Oncol Lett"},{"issue":"1","key":"848_CR7","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1002\/jso.23042","volume":"106","author":"YJ McConnell","year":"2012","unstructured":"McConnell YJ, Giacomantonio CA. Malignant triton tumors\u2013complete surgical resection and adjuvant radiotherapy associated with improved survival. J Surg Oncol. 2012;106(1):51\u20136.","journal-title":"J Surg Oncol"},{"key":"848_CR8","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/j.ijscr.2019.08.020","volume":"62","author":"I Chaudhry","year":"2019","unstructured":"Chaudhry I, Algazal T, Cheema A, Al FA, Al MN, Mutairi H, Abbas A, Amr S. Mediastinal malignant triton tumor: a rare case series and review of literature. Int J Surg Case Rep. 2019;62:115\u20139.","journal-title":"Int J Surg Case Rep"},{"key":"848_CR9","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1186\/s40001-015-0172-y","volume":"20","author":"L Gao","year":"2015","unstructured":"Gao L, Song H, Mu K, Wang J, Guo B, Shi B, Li G. Primary epididymis malignant triton tumor: case report and review of the literature. Eur J Med Res. 2015;20:79.","journal-title":"Eur J Med Res"},{"issue":"9","key":"848_CR10","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1016\/j.ijscr.2014.07.014","volume":"5","author":"A Zakzouk","year":"2014","unstructured":"Zakzouk A, Hammad F, Langlois O, Aziz M, Marie JP, Choussy O. Malignant triton tumour of the sinonasal tract: case report and literature review. Int J Surg Case Rep. 2014;5(9):608\u201312.","journal-title":"Int J Surg Case Rep"},{"issue":"2","key":"848_CR11","first-page":"426","volume":"32","author":"JM Woodruff","year":"1973","unstructured":"Woodruff JM, Chernik NL, Smith MC, Millett WB, Foote FJ. Peripheral nerve tumors with rhabdomyosarcomatous differentiation (malignant \u201cTriton\u201d tumors). Cancer-Am Cancer Soc. 1973;32(2):426\u201339.","journal-title":"Cancer-Am Cancer Soc"},{"issue":"5","key":"848_CR12","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1177\/1066896915583996","volume":"23","author":"K Thway","year":"2015","unstructured":"Thway K, Hamarneh W, Miah AB, Fisher C. Malignant peripheral nerve sheath tumor with rhabdomyosarcomatous and glandular elements: rare epithelial differentiation in a triton tumor. Int J Surg Pathol. 2015;23(5):377\u201383.","journal-title":"Int J Surg Pathol"},{"key":"848_CR13","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1102\/1470-7330.2012.0043","volume":"12","author":"SC Kamran","year":"2012","unstructured":"Kamran SC, Shinagare AB, Howard SA, Hornick JL, Ramaiya NH. A-Z of malignant peripheral nerve sheath tumors. Cancer Imaging. 2012;12:475\u201383.","journal-title":"Cancer Imaging"},{"issue":"1","key":"848_CR14","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.pedneo.2013.01.013","volume":"56","author":"TH Jaing","year":"2015","unstructured":"Jaing TH, Chuang CC, Jung SM, Wu CT, Tseng CK, Chen CS. Malignant triton tumor of the cervical spine: report of one case and review of the literature. Pediatr Neonatol. 2015;56(1):58\u201361.","journal-title":"Pediatr Neonatol"},{"issue":"2","key":"848_CR15","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1634\/theoncologist.2013-0328","volume":"19","author":"M Farid","year":"2014","unstructured":"Farid M, Demicco EG, Garcia R, Ahn L, Merola PR, Cioffi A, Maki RG. Malignant peripheral nerve sheath tumors. Oncologist. 2014;19(2):193\u2013201.","journal-title":"Oncologist"},{"issue":"7","key":"848_CR16","doi-asserted-by":"publisher","first-page":"808","DOI":"10.1016\/j.ejso.2006.04.008","volume":"32","author":"E Aldlyami","year":"2006","unstructured":"Aldlyami E, Dramis A, Grimer RJ, Abudu A, Carter SR, Tillman RM. Malignant triton tumour of the thigh\u2013a retrospective analysis of nine cases. Eur J Surg Oncol. 2006;32(7):808\u201310.","journal-title":"Eur J Surg Oncol"},{"key":"848_CR17","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2019.05.015","volume":"183","author":"S Tish","year":"2019","unstructured":"Tish S, Ross L, Habboub G, Roser F, Recinos PF. Malignant triton tumor diagnosed twelve years after radiosurgically treated vestibular schwannoma. Clin Neurol Neurosurg. 2019;183: 105367.","journal-title":"Clin Neurol Neurosurg"},{"issue":"5","key":"848_CR18","doi-asserted-by":"publisher","first-page":"874","DOI":"10.3171\/jns.1992.76.5.0874","volume":"76","author":"DH Han","year":"1992","unstructured":"Han DH, Kim DG, Chi JG, Park SH, Jung HW, Kim YG. Malignant triton tumor of the acoustic nerve Case report. J Neurosurg. 1992;76(5):874\u20137.","journal-title":"J Neurosurg"},{"issue":"1","key":"848_CR19","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/0899-7071(93)90014-E","volume":"17","author":"S Nosaka","year":"1993","unstructured":"Nosaka S, Kao SC. MRI of malignant \u201ctriton\u201d tumor in a child. Clin Imaging. 1993;17(1):53\u20135.","journal-title":"Clin Imaging"},{"issue":"2","key":"848_CR20","doi-asserted-by":"publisher","first-page":"371","DOI":"10.2214\/AJR.07.2065","volume":"189","author":"SD Allen","year":"2007","unstructured":"Allen SD, Moskovic EC, Fisher C, Thomas JM. Adult rhabdomyosarcoma: cross-sectional imaging findings including histopathologic correlation. AJR Am J Roentgenol. 2007;189(2):371\u20137.","journal-title":"AJR Am J Roentgenol"},{"issue":"5","key":"848_CR21","doi-asserted-by":"publisher","first-page":"1645","DOI":"10.1016\/S0003-4975(02)04825-7","volume":"75","author":"L Lang-Lazdunski","year":"2003","unstructured":"Lang-Lazdunski L, Pons F, Jancovici R. Malignant \u201cTriton\u201d tumor of the posterior mediastinum: prolonged survival after staged resection. ANN Thorac Surg. 2003;75(5):1645\u20138.","journal-title":"ANN Thorac Surg"},{"issue":"3","key":"848_CR22","doi-asserted-by":"publisher","first-page":"230","DOI":"10.2478\/raon-2013-0047","volume":"47","author":"SC Kamran","year":"2013","unstructured":"Kamran SC, Shinagare AB, Howard SA, Nishino M, Hornick JL, Krajewski KM, Ramaiya NH. Intrathoracic malignant peripheral nerve sheath tumors: imaging features and implications for management. Radiol Oncol. 2013;47(3):230\u20138.","journal-title":"Radiol Oncol"}],"container-title":["BMC Medical Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12880-022-00848-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12880-022-00848-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12880-022-00848-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,14]],"date-time":"2022-07-14T12:09:29Z","timestamp":1657800569000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcmedimaging.biomedcentral.com\/articles\/10.1186\/s12880-022-00848-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,14]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["848"],"URL":"https:\/\/doi.org\/10.1186\/s12880-022-00848-9","relation":{},"ISSN":["1471-2342"],"issn-type":[{"type":"electronic","value":"1471-2342"}],"subject":[],"published":{"date-parts":[[2022,7,14]]},"assertion":[{"value":"11 March 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 July 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 July 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"We have received the written informed consent for their images and personal or clinical details to be published from these two patients and their immediate families.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declares that there is no conflict of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"125"}}