{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T21:55:23Z","timestamp":1793483723437,"version":"4.5.0"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T00:00:00Z","timestamp":1668729600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T00:00:00Z","timestamp":1668729600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Med Imaging"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Automatic segmentation of brain tumours using deep learning algorithms is currently one of the research hotspots in the medical image segmentation field. An improved U-Net network is proposed to segment brain tumours to improve the segmentation effect of brain tumours.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>To solve the problems of other brain tumour segmentation models such as U-Net, including insufficient ability to segment edge details and reuse feature information, poor extraction of location information and the commonly used binary cross-entropy and Dice loss are often ineffective when used as loss functions for brain tumour segmentation models, we propose a serial encoding\u2013decoding structure, which achieves improved segmentation performance by adding hybrid dilated convolution (HDC) modules and concatenation between each module of two serial networks. In addition, we propose a new loss function to focus the model more on samples that are difficult to segment and classify. We compared the results of our proposed model and the commonly used segmentation models under the IOU, PA, Dice, precision, Hausdorf95, and ASD metrics.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The performance of the proposed method outperforms other segmentation models in each metric. In addition, the schematic diagram of the segmentation results shows that the segmentation results of our algorithm are closer to the ground truth, showing more brain tumour details, while the segmentation results of other algorithms are smoother.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Our algorithm has better semantic segmentation performance than other commonly used segmentation algorithms. The technology we propose can be used in the brain tumour diagnosis to provide better protection for patients' later treatments.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12880-022-00931-1","type":"journal-article","created":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T09:51:09Z","timestamp":1668765069000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":50,"title":["Brain tumour segmentation based on an improved U-Net"],"prefix":"10.1186","volume":"22","author":[{"given":"Ping","family":"Zheng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xunfei","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenbo","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,11,18]]},"reference":[{"issue":"12","key":"931_CR1","doi-asserted-by":"publisher","first-page":"e855","DOI":"10.1016\/j.na.2008.12.042","volume":"71","author":"G Mayer","year":"2009","unstructured":"Mayer G, Vrscay E. 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