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However, the advantages of SR-DLR at coronary computed tomography angiography (CCTA) have not been fully investigated. The present study aimed to compare the image quality of the coronary arteries and in-stent lumen between SR-DLR and model-based iterative reconstruction (MBIR). We prospectively enrolled 70 patients (median age, 69 years; interquartile range [IQR], 59\u201375 years; 50 men) who underwent CCTA using a 320-detector row CT scanner between January and August 2022. The image noise in the ascending aorta, left atrium, and septal wall of the ventricle was measured, and the signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) in the proximal coronary arteries were calculated. Of the twenty stents, stent strut thickness and luminal diameter were quantitatively evaluated. The image noise on SR-DLR was significantly lower than that on MBIR (median 22.1 HU; IQR, 19.3\u201324.9 HU vs. 27.4 HU; IQR, 24.2\u201331.2 HU, p\u2009&lt;\u20090.01), whereas the SNR (median 16.3; IQR, 11.8\u201321.8 vs. 13.7; IQR, 9.9\u201318.4, p\u2009=\u20090.01) and CNR (median 24.4; IQR, 15.5\u201330.2 vs. 19.2; IQR, 14.1\u201323.2, p\u2009&lt;\u20090.01) on SR-DLR were significantly higher than that on MBIR. Stent struts were significantly thinner (median, 0.68\u00a0mm; IQR, 0.61\u20130.78\u00a0mm vs. 0.81\u00a0mm; IQR, 0.72\u20130.96\u00a0mm, p\u2009&lt;\u20090.01) and in-stent lumens were significantly larger (median, 1.84\u00a0mm; IQR, 1.65\u20132.26\u00a0mm vs. 1.52\u00a0mm; IQR, 1.28\u20132.25\u00a0mm, p\u2009&lt;\u20090.01) on SR-DLR than on MBIR. Although further large-scale studies using invasive coronary angiography as the reference standard, comparative studies with UHRCT, and studies in more challenging population for CCTA are needed, this study\u2019s initial experience with SR-DLR would improve the utility of CCTA in daily clinical practice due to the better image quality of the coronary arteries and in-stent lumen at CCTA compared with conventional MBIR.<\/jats:p>","DOI":"10.1186\/s12880-023-01139-7","type":"journal-article","created":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T11:03:00Z","timestamp":1698663780000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Super-resolution deep learning reconstruction at coronary computed tomography angiography to evaluate the coronary arteries and in-stent lumen: an initial experience"],"prefix":"10.1186","volume":"23","author":[{"given":"Makoto","family":"Orii","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Misato","family":"Sone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Osaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuta","family":"Ueyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuya","family":"Chiba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadashi","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunihiro","family":"Yoshioka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,10,30]]},"reference":[{"key":"1139_CR1","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1016\/j.jacc.2005.05.056","volume":"46","author":"GL Raff","year":"2005","unstructured":"Raff GL, Gallagher MJ, O\u2019Neill WW, Goldstein JA. 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Ltd. Other authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The study was approved by the institution\u2019s human research committee (Iwate Medical University). All methods were carried out in accordance with relevant guidelines and regulations, and informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not Applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}],"article-number":"171"}}