{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T18:27:00Z","timestamp":1773685620914,"version":"3.50.1"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,1,16]],"date-time":"2025-01-16T00:00:00Z","timestamp":1736985600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,1,16]],"date-time":"2025-01-16T00:00:00Z","timestamp":1736985600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Med Imaging"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aims to investigate the predictive effectiveness of bedside lung ultrasound score (LUS) in conjunction with rapid shallow breathing index (RSBI) and oxygenation index (P\/F ratio) for weaning pediatric patients from mechanical ventilation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a retrospective study. Eighty-two critically ill pediatric patients, who were admitted to the Pediatric Intensive Care Unit (PICU) and underwent mechanical ventilation from January 2023 to April 2024, were enrolled in this study. Prior to weaning, all patients underwent bedside LUS, with concurrent measurements of their RSBI and P\/F ratio. Patients were followed up for weaning outcomes and categorized into successful and failed weaning groups based on these outcomes. Differences in clinical baseline data, LUS scores, RSBI and P\/F ratios between the two groups were compared. The predictive value of LUS scores, RSBI and P\/F ratios for weaning outcomes was assessed using receiver operating characteristic (ROC) curves and the area under the curve (AUC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Out of the 82 subjects, 73 (89.02%) successfully weaned, while 9 (10.98%) failed. No statistically significant differences were observed in age, gender, BMI, and respiratory failure-related comorbidities between the successful and failed weaning groups (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&gt;\u20090.05). Compared to the successful weaning group, the failed weaning group exhibited longer hospital and intubation durations, higher LUS and RSBI, and lower P\/F ratios, with statistically significant differences (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.05). An LUS score\u2009\u2265\u200915.5 was identified as the optimal cutoff for predicting weaning failure, with superior predictive power compared to RSBI and P\/F ratios. The combined use of LUS, RSBI and P\/F ratios for predicting weaning outcomes yielded a larger area under the curve, indicating higher predictive efficacy.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The LUS demonstrates a high predictive value for the weaning outcomes of pediatric patients on mechanical ventilation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12880-025-01552-0","type":"journal-article","created":{"date-parts":[[2025,1,16]],"date-time":"2025-01-16T07:49:29Z","timestamp":1737013769000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Value of combining lung ultrasound score with oxygenation and functional indices in determining weaning timing for critically ill pediatric patients"],"prefix":"10.1186","volume":"25","author":[{"given":"Ximeng","family":"Hao","sequence":"first","affiliation":[]},{"given":"Hongnian","family":"Duan","sequence":"additional","affiliation":[]},{"given":"Qiushuang","family":"Li","sequence":"additional","affiliation":[]},{"given":"Dan","family":"Wang","sequence":"additional","affiliation":[]},{"given":"Xin","family":"Yin","sequence":"additional","affiliation":[]},{"given":"Zhiyan","family":"Di","sequence":"additional","affiliation":[]},{"given":"Shanshan","family":"Du","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2025,1,16]]},"reference":[{"issue":"2","key":"1552_CR1","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1111\/pan.14364","volume":"32","author":"L Sequera-Ramos","year":"2022","unstructured":"Sequera-Ramos L, Garcia-Marcinkiewicz A, Riva T, et al. 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This study was conducted under the Declaration of Helsinki.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval and consent to participate"}},{"value":"Informed consent was obtained from all patients\u2019 parents or legal guardians in accordance with the ethics committee guidelines for the publication of this manuscript.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"All authors declare that they have no competing interests and any accompanying images. All authors agreed to publish this work.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"19"}}