{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T19:25:11Z","timestamp":1774121111129,"version":"3.50.1"},"reference-count":85,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2015,11,30]],"date-time":"2015-11-30T00:00:00Z","timestamp":1448841600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Med Inform Decis Mak"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1186\/s12911-015-0222-y","type":"journal-article","created":{"date-parts":[[2015,11,30]],"date-time":"2015-11-30T20:22:34Z","timestamp":1448914954000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["A generic solution for web-based management of pseudonymized data"],"prefix":"10.1186","volume":"15","author":[{"given":"Ronald","family":"Lautenschl\u00e4ger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florian","family":"Kohlmayer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabian","family":"Prasser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klaus A.","family":"Kuhn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,11,30]]},"reference":[{"key":"222_CR1","volume-title":"Guidelines for human biobanks and genetic research databases","author":"HBGRDs","year":"2008","unstructured":"HBGRDs. Guidelines for human biobanks and genetic research databases. 2008. http:\/\/www.oecd.org\/science\/biotech\/guidelinesforhumanbiobanksandgeneticresearchdatabaseshbgrds.htm . Accessed 28 September 2015."},{"key":"222_CR2","volume-title":"Public population project in genomics and society","author":"P3G","year":"2015","unstructured":"P3G. Public population project in genomics and society. 2015. http:\/\/p3g.org . Accessed 28 September 2015."},{"key":"222_CR3","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1038\/nbt.1958","volume":"29","author":"HE Wichmann","year":"2011","unstructured":"Wichmann HE, Kuhn KA, Waldenberger M, Schmelcher D, Schuffenhauer S, Meitinger T, et al. Comprehensive catalog of european biobanks. Nat Biotechnol. 2011;29:795\u20137. doi: 10.1038\/nbt.1958 .","journal-title":"Nat Biotechnol"},{"key":"222_CR4","volume-title":"Building data bridges from biology to medicine in Europe","author":"BioMedBridges","year":"2015","unstructured":"BioMedBridges. Building data bridges from biology to medicine in Europe. 2015. http:\/\/www.biomedbridges.eu . Accessed 28 September 2015."},{"issue":"4","key":"222_CR5","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1504\/IJIEM.2010.035624","volume":"6","author":"A Appari","year":"2010","unstructured":"Appari A, Johnson ME. Information security and privacy in healthcare: current state of research. Int J Internet Enterp Manag. 2010;6(4):279\u2013314. doi: 10.1504\/IJIEM.2010.035624 .","journal-title":"Int J Internet Enterp Manag"},{"key":"222_CR6","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1197\/jamia.M1603","volume":"12","author":"B Malin","year":"2005","unstructured":"Malin B. An evaluation of the current state of genomic data privacy protection technology and a roadmap for the future. J Am Med Inform Assoc. 2005;12:28\u201334.","journal-title":"J Am Med Inform Assoc"},{"key":"222_CR7","doi-asserted-by":"publisher","unstructured":"Ayday E, De Cristofaro E, Hubaux J-P, Tsudik, G. The chills and thrills of whole genome sequencing. IEEE Computer. 2013;99:1. doi: 10.1109\/MC.2013.333 .","DOI":"10.1109\/MC.2013.333"},{"key":"222_CR8","unstructured":"European Parliament and Council of the European Union: European Parliament and council directive 95\/46\/EC of 24 October 1995 on the protection of individuals with regard to the processing of personal data and on the free movement of such data. Official Journal L 1995;281:31\u201350."},{"key":"222_CR9","unstructured":"European Commission. Proposal for a regulation of the European Parliament and of the Council on the protection of individuals with regard to the processing of personal data and on the free movement of such data (General data protection regulation). Outcome of the European Parliament\u2019s first reading (Strasbourg, 10 to 13 March 2014). Brussels. 2014."},{"key":"222_CR10","unstructured":"Council of Europe: Recommendation Rec(2006) 4 of the Committee of Ministers to member states on research on biological materials of human origin. 958th meeting. 15 March 2006."},{"key":"222_CR11","volume-title":"HIPAA administrative simplification regulation, 45 CFR Parts 160, 162, and 164","author":"U.S. Department of Health and Human Services Office for Civil Rights","year":"2013","unstructured":"U.S. Department of Health and Human Services Office for Civil Rights. HIPAA administrative simplification regulation, 45 CFR Parts 160, 162, and 164. 2013."},{"key":"222_CR12","volume-title":"UK biobank ethics and governance framework (version 3.0)","author":"UK Biobank","year":"2007","unstructured":"UK Biobank. UK biobank ethics and governance framework (version 3.0). 2007. https:\/\/www.ukbiobank.ac.uk\/wp-content\/uploads\/2011\/05\/EGF20082.pdf . Accessed 28 September 2015."},{"key":"222_CR13","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1517\/phgs.4.2.209.22627","volume":"4","author":"H Hakonarson","year":"2003","unstructured":"Hakonarson H, Gulcher JR, Stefansson K. deCODE genetics, Inc. Pharmacogenomics. 2003;4:209\u201315.","journal-title":"Pharmacogenomics"},{"key":"222_CR14","unstructured":"The German National Cohort: http:\/\/nationale-kohorte.de\/informationen-auf-englisch\/ (2015). Accessed 30 November 2015."},{"key":"222_CR15","unstructured":"Federal Data Protection Act in the version promulgated on 14 January 2003 (Federal Law Gazette I p. 66), as most recently amended by Article 1 of the Act of 14 August 2009 (Federal Law Gazette I p. 2814). 2009."},{"key":"222_CR16","unstructured":"Republic of Italy. Personal data protection code. legislative decree No. 196, (196), 1\u2013186. 2003."},{"issue":"Suppl 1","key":"222_CR17","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1258\/135581903766468800","volume":"8","author":"W Lowrance","year":"2003","unstructured":"Lowrance W. Learning from experience: privacy and the secondary use of data in health research. J Health Serv Res Policy. 2003;8 Suppl 1:2\u20137. doi: 10.1258\/135581903766468800 .","journal-title":"J Health Serv Res Policy"},{"issue":"7650","key":"222_CR18","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1136\/bmj.333.7560.196","volume":"333","author":"D Kalra","year":"2006","unstructured":"Kalra D, Gertz R, Singleton P, Inskip HM. Confidentiality of personal health information used for research. BMJ. 2006;333(7650):196\u20138. doi: 10.1136\/bmj.333.7560.196 .","journal-title":"BMJ"},{"key":"222_CR19","unstructured":"International Organization for Standardization (ISO). Health informatics - pseudonymization. ISO\/TS 25237:2008(E). 2008."},{"key":"222_CR20","doi-asserted-by":"crossref","unstructured":"Pommerening K, Drepper J, Helbing K, Ganslandt T. Leitfaden zum Datenschutz in medizinischen Forschungsprojekten. 1st ed. Berlin: MWV; 2014. ISBN-10: 3954661233.","DOI":"10.32745\/9783954662951"},{"key":"222_CR21","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1055\/s-0038-1628626","volume":"46","author":"A Winter","year":"2007","unstructured":"Winter A, Funkat G, Haeber A, Mauz-Koerholz C, Pommerening K, Smers S, et al. Integrated information systems for translational medicine. Methods Inf Med. 2007;46:601\u20137.","journal-title":"Methods Inf Med"},{"key":"222_CR22","first-page":"5","volume-title":"eHealth: Combining health telematics, telemedicine, biomedical engineering and bioinformatics to the edge","author":"K Pommerening","year":"2008","unstructured":"Pommerening K, Sax U, M\u00fcller T, Speer R, Ganslandt T, Drepper J, et al. Integrating eHealth and medical research: The TMF data protection scheme. In: Blobel B, Pharow P, Zvarova J, Lopez D, editors. eHealth: Combining health telematics, telemedicine, biomedical engineering and bioinformatics to the edge. Berlin: Akademische Verlagsgesellschaft Aka GmbH; 2008. p. 5\u201310."},{"issue":"6","key":"222_CR23","doi-asserted-by":"publisher","first-page":"601","DOI":"10.3414\/ME09-02-0058","volume":"49","author":"K Helbing","year":"2010","unstructured":"Helbing K, Demiroglu SY, Rakebrandt F, Pommerening K, Rienhoff O, Sax U. A data protection scheme for medical research networks. Methods Inf Med. 2010;49(6):601\u20137. doi: 10.3414\/ME09-02-0058 .","journal-title":"Methods Inf Med"},{"key":"222_CR24","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/j.ics.2005.03.185","volume":"1281","author":"L Brinkmann","year":"2005","unstructured":"Brinkmann L, Klein A, Ganslandt T, \u00dcckert F. Implementing a data safety and protection concept for a web-based exchange of variable medical image data. Int Congr Ser. 2005;1281:191\u20135. doi: 10.1016\/j.ics.2005.03.185 .","journal-title":"Int Congr Ser"},{"key":"222_CR25","first-page":"730","volume":"150","author":"M Spitzer","year":"2009","unstructured":"Spitzer M, Ullrich T, Ueckert F. Securing a web-based teleradiology platform according to German law and \u201cBest Practices\u201d. Stud Health Technol Inform. 2009;150:730\u20134.","journal-title":"Stud Health Technol Inform"},{"issue":"1","key":"222_CR26","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/s12911-014-0123-5","volume":"15","author":"M Lablans","year":"2015","unstructured":"Lablans M, Borg A, \u00dcckert F. A RESTful interface to pseudonymization services in modern web applications. BMC Med Inform Decis Mak. 2015;15(1):2. doi: 10.1186\/s12911-014-0123-5 .","journal-title":"BMC Med Inform Decis Mak"},{"key":"222_CR27","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1186\/1750-1172-7-66","volume":"7","author":"B Kalman","year":"2012","unstructured":"Kalman B, Lautenschlaeger R, Kohlmayer F, B\u00fcchner B, Kmiec T, Klopstock T, et al. An international registry for neurodegeneration with brain iron accumulation. Orphanet J Rare Dis. 2012;7:66. doi: 10.1186\/1750-1172-7-66 .","journal-title":"Orphanet J Rare Dis"},{"key":"222_CR28","unstructured":"m4 Leading-Egde Cluster: m4 data integration systems. http:\/\/www.m4.de\/en\/leading-edge-cluster\/m4-data-integrationsystem.html (2015). Accessed 30 November 2015."},{"issue":"3","key":"222_CR29","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1007\/s11825-012-0338-8","volume":"24","author":"B B\u00fcchner","year":"2012","unstructured":"B\u00fcchner B, Gallenm\u00fcller C, Lautenschl\u00e4ger R, Kuhn KA, Wittig I, Sch\u00f6ls L, et al. Das deutsche Netzwerk f\u00fcr mitochondriale Erkrankungen (mitoNET). Med Genet. 2012;24(3):193\u20139. doi: 10.1007\/s11825-012-0338-8 .","journal-title":"Med Genet"},{"key":"222_CR30","unstructured":"Sommerville I: Software engineering. 9th ed. Addison-Wesley; 2010:792. ISBN-10: 0137035152."},{"issue":"12","key":"222_CR31","doi-asserted-by":"publisher","first-page":"1180","DOI":"10.1038\/mp.2012.11","volume":"17","author":"SY Demiroglu","year":"2012","unstructured":"Demiroglu SY, Skrowny D, Quade M, Schwanke J, Budde M, Gullatz V, et al. Managing sensitive phenotypic data and biomaterial in large-scale collaborative psychiatric genetic research projects: practical considerations. Mol Psychiatry. 2012;17(12):1180\u20135. doi: 10.1038\/mp.2012.11 .","journal-title":"Mol Psychiatry"},{"key":"222_CR32","doi-asserted-by":"publisher","first-page":"364","DOI":"10.3414\/ME14-01-0133","volume":"54","author":"M Bialke","year":"2015","unstructured":"Bialke M, Bahls T, Havemann C, Piegsa J, Weitmann K, Wegner T, et al. MOSAIC \u2013 a modular approach to data management in epidemiological studies. Methods Inf Med. 2015;54:364\u201371. doi: 10.3414\/ME14-01-0133 .","journal-title":"Methods Inf Med"},{"issue":"3","key":"222_CR33","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1016\/j.cmpb.2010.12.016","volume":"107","author":"J Meyer","year":"2012","unstructured":"Meyer J, Ostrzinski S, Fredrich D, Havemann C, Krafczyk J, Hoffmann W. Efficient data management in a large-scale epidemiology research project. Comput Methods Programs Biomed. 2012;107(3):425\u201335. doi: 10.1016\/j.cmpb.2010.12.016 .","journal-title":"Comput Methods Programs Biomed"},{"key":"222_CR34","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1186\/1745-6215-12-85","volume":"12","author":"C Ohmann","year":"2011","unstructured":"Ohmann C, Kuchinke W, Canham S, Lauritsen J, Salas N, Schade-Brittinger C, et al. Standard requirements for GCP-compliant data management in multinational clinical trials. Trials. 2011;12:85. doi: 10.1186\/1745-6215-12-85 .","journal-title":"Trials"},{"key":"222_CR35","unstructured":"Kohlmayer F, Lautenschl\u00e4ger R, Wurst SHR, Klopstock T, Prokisch H, Meitinger T, et al. Konzept f\u00fcr ein deutschlandweites Krankheitsnetz am Beispiel von mitoREGISTER. GI Jahrestagung. 2010:746\u2013751."},{"issue":"5","key":"222_CR36","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1002\/mds.21331","volume":"22","author":"K Eggert","year":"2007","unstructured":"Eggert K, W\u00fcllner U, Antony G, Gasser T, Janetzky B, Klein C, et al. Data protection in biomaterial banks for parkinson\u2019s disease research: the model of GEPARD (gene bank parkinson\u2019s disease germany). Mov Disord. 2007;22(5):611\u2013318. doi: 10.1002\/mds.21331 .","journal-title":"Mov Disord"},{"issue":"Pt 2","key":"222_CR37","doi-asserted-by":"publisher","first-page":"1334","DOI":"10.3233\/978-1-60750-588-4-1334","volume":"160","author":"A Dangl","year":"2010","unstructured":"Dangl A, Demiroglu SY, Gaedcke J, Helbing K, Jo P, Rakebrandt F, et al. The IT-infrastructure of a biobank for an academic medical center. Stud Health Technol Inform. 2010;160(Pt 2):1334\u20138. doi: 10.3233\/978-1-60750-588-4-1334 .","journal-title":"Stud Health Technol Inform"},{"key":"222_CR38","doi-asserted-by":"publisher","unstructured":"Jin J, Ahn G-J, Hu H, Covington MJ, Zhang X. Patient-centric authorization framework for sharing electronic health records. In Proc 14th ACM Symp Access Control Model Technol. 2009; 125\u2013134; doi 10.1145\/1542207.1542228 .","DOI":"10.1145\/1542207.1542228"},{"key":"222_CR39","isbn-type":"print","first-page":"123","volume-title":"Web services: Concepts, architectures and applications (Data-centric systems and applications)","author":"G Alonso","year":"2004","unstructured":"Alonso G, Casati F, Kuno H, Machiraju V. Web services: Concepts, architectures and applications (Data-centric systems and applications). Berlin Heidelberg: Springer; 2004. p. 123\u201349. ISBN 3642078885.","ISBN":"https:\/\/id.crossref.org\/isbn\/3642078885"},{"key":"222_CR40","first-page":"36","volume-title":"BIS 2000, 4th Int Conf on Bus Inf Syst","author":"P Dadam","year":"2000","unstructured":"Dadam P, Reichert M, Kuhn KA. Clinical workflows-the killer application for process-oriented information systems? In: Abramowicz W, Orlowska ME, editors. BIS 2000, 4th Int Conf on Bus Inf Syst. London: Springer; 2000. p. 36\u201359."},{"key":"222_CR41","volume-title":"Usability issues in web site design","author":"N Bevan","year":"1999","unstructured":"Bevan N. Usability issues in web site design. 1999. http:\/\/experiencelab.typepad.com\/files\/usability-issues-in-website-design-1.pdf . Accessed 28 September 2015."},{"key":"222_CR42","unstructured":"Goldberg SI, Niemierko A, Turchin A. Analysis of data errors in clinical research databases. AMIA Annu Symp Proc. 2008:242\u2013246."},{"key":"222_CR43","unstructured":"The HL7 CCOW Standard: http:\/\/www.hl7.com.au\/CCOW.htm (2006). Accessed 28 September 2015."},{"key":"222_CR44","unstructured":"Demiroglu SY, Skrowny D, Schulze TG. Adaption of the identity management regarding new requirements of a long-term psychosis biobank. In: Moen A, Andersen SK, Aarts J, Hurlen P, editors. In Proc 23rd Int Conf European Federation Med Inform. Oslo. MIE 2011. 2011:1\u20133."},{"key":"222_CR45","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1186\/s12967-015-0545-6","volume":"13","author":"M Bialke","year":"2015","unstructured":"Bialke M, Penndorf P, Wegner T, Bahls T, Havemann C, Piegsa J, et al. A workflow-driven approach to integrate generic software modules in a trusted third party. J Transl Med. 2015;13:176. doi: 10.1186\/s12967-015-0545-6 .","journal-title":"J Transl Med"},{"key":"222_CR46","unstructured":"AngularJS: https:\/\/angularjs.org (2015). Accessed 28 September 2015."},{"key":"222_CR47","unstructured":"BACKBONE.JS: http:\/\/backbonejs.org (2015). Accessed 28 September 2015."},{"key":"222_CR48","doi-asserted-by":"publisher","unstructured":"Jackson C, Bortz A, Boneh D, Mitchell JC. Protecting browser state from web privacy attacks. Proc Int Conf World Wide Web. 2006:737\u2013744; doi: 10.1145\/1135777.1135884 .","DOI":"10.1145\/1135777.1135884"},{"key":"222_CR49","doi-asserted-by":"publisher","unstructured":"Jackson C, Wang HJ. Subspace: Secure cross-domain communication for web mashups. Proc Int Conf World Wide Web. 2007:611\u2013620; doi: 10.1145\/1242572.1242655 .","DOI":"10.1145\/1242572.1242655"},{"key":"222_CR50","doi-asserted-by":"publisher","unstructured":"De Ryck P, Decat M, Desmet L, Piessens F, Joosen W. Security of web mashups: a survey. Proc Nord Conf Sec IT Syst. 2012:223\u2013238; doi: 10.1007\/978-3-642-27937-9_16 .","DOI":"10.1007\/978-3-642-27937-9_16"},{"key":"222_CR51","unstructured":"Son S, Shmatikov V. The postman always rings twice: attacking and defending postMessage in HTML5 websites. In: ISOC Network and Distributed System Security Symposium, NDSS 2013. 2013."},{"key":"222_CR52","unstructured":"JGroups: http:\/\/www.jgroups.org (2015). Accessed 28 September 2015."},{"key":"222_CR53","volume-title":"RFC 4120: the Kerberos network authentication service (V5)","author":"C Neuman","year":"2005","unstructured":"Neuman C, Kohl J. RFC 4120: the Kerberos network authentication service (V5). 2005. http:\/\/www.ietf.org\/rfc\/rfc4120.txt . Accessed 28 September 2015."},{"key":"222_CR54","unstructured":"Shibboleth 3: a new identity platform. 2013. https:\/\/shibboleth.net\/documents\/business-case.pdf . Accessed 28 September 2015."},{"key":"222_CR55","unstructured":"Anderson A, Lockhart H. SAML 2.0 profile of XACML. OASIS Open 2004. http:\/\/docs.oasis-open.org\/xacml\/access_control-xacml-2.0-saml_profile-spec-cd-01.pdf . Accessed 28 September 2015."},{"key":"222_CR56","volume-title":"RFC 791: Darpa internet program protocol specification","author":"University of Southern California","year":"1981","unstructured":"University of Southern California. RFC 791: Darpa internet program protocol specification. 1981. https:\/\/tools.ietf.org\/html\/rfc791 . Accessed 28 September 2015."},{"key":"222_CR57","unstructured":"Jones MB. The emerging JSON-based identity protocol suite. W3C workshop on identity in the browser. 2011:1\u20133."},{"key":"222_CR58","volume-title":"FP7-HEALTH - FP7 specific programme \u2018cooperation\u2019 - research theme: \u2018health\u2019","author":"European Commission","year":"2007","unstructured":"European Commission. FP7-HEALTH - FP7 specific programme \u2018cooperation\u2019 - research theme: \u2018health\u2019. 2007. http:\/\/cordis.europa.eu\/programme\/rcn\/852_en.html . Accessed 28 September 2015."},{"key":"222_CR59","unstructured":"OATH Standard: http:\/\/www.openauthentication.org (2015). Accessed 28 September 2015."},{"issue":"5","key":"222_CR60","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1016\/j.ajhg.2008.09.017","volume":"83","author":"PN Robinson","year":"2008","unstructured":"Robinson PN, K\u00f6hler S, Bauer S, Seelow D, Horn D, Mundlos S. The human phenotype ontology: a tool for annotating and analyzing human hereditary disease. Am J Hum Genet. 2008;83(5):610\u20135. doi: 10.1016\/j.ajhg.2008.09.017 .","journal-title":"Am J Hum Genet"},{"issue":"12","key":"222_CR61","doi-asserted-by":"publisher","first-page":"1932","DOI":"10.1212\/01.wnl.0000219759.72195.41","volume":"66","author":"AM Schaefer","year":"2012","unstructured":"Schaefer AM, Phoenix C, Elson JL. Mitochondrial disease in adults: a scale to monitor progression and treatment mitochondrial disease in adults. Neurology. 2012;66(12):1932\u20134.","journal-title":"Neurology"},{"issue":"6","key":"222_CR62","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1017\/S0012162299000870","volume":"41","author":"MJ Barry","year":"1999","unstructured":"Barry MJ, VanSwearingen JM, Albright AL. Reliability and responsiveness of the barry-albright dystonia scale. Dev Med Child Neurol. 1999;41(6):404\u201311.","journal-title":"Dev Med Child Neurol"},{"issue":"11","key":"222_CR63","doi-asserted-by":"publisher","first-page":"1717","DOI":"10.1212\/01.wnl.0000219042.60538.92","volume":"66","author":"T Schmitz-H\u00fcbsch","year":"2006","unstructured":"Schmitz-H\u00fcbsch T, Du Montcel ST, Baliko L, Berciano J, Boesch S, Depondt C, et al. Scale for the assessment and rating of ataxia: development of a new clinical scale. Neurology. 2006;66(11):1717\u201320.","journal-title":"Neurology"},{"issue":"1","key":"222_CR64","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1186\/1472-6947-13-75","volume":"13","author":"H Aamot","year":"2013","unstructured":"Aamot H, Kohl CD, Richter D, Knaup-Gregori P. Pseudonymization of patient identifiers for translational research. BMC Med Inform Decis Mak. 2013;13(1):75. doi: 10.1186\/1472-6947-13-75 .","journal-title":"BMC Med Inform Decis Mak"},{"key":"222_CR65","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1007\/978-3-642-01209-9_5","volume-title":"Computer and Information Science","author":"T Neubauer","year":"2009","unstructured":"Neubauer T, Kolb M. An evaluation of technologies for the pseudonymization of medical data. In: Computer and Information Science. Berlin: Springer; 2009. p. 47\u201360. doi: 10.1007\/978-3-642-01209-9_5 ."},{"key":"222_CR66","doi-asserted-by":"publisher","DOI":"10.1267\/METH05020193","author":"D Kalra","year":"2005","unstructured":"Kalra D, Singleton P, Milan J, MacKay J, Detmer D, Rector A, et al. Security and confidentiality approach for the clinical e-science framework (CLEF). Methods Inf Med. 2005. doi: 10.1267\/METH05020193 .","journal-title":"Methods Inf Med"},{"issue":"3","key":"222_CR67","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1136\/jamia.2009.002725","volume":"17","author":"G Loukides","year":"2010","unstructured":"Loukides G, Denny JC, Malin B. The disclosure of diagnosis codes can breach research participants\u2019 privacy. J Am Med Inform Assoc. 2010;17(3):322\u20137. doi: 10.1136\/jamia.2009.002725 .","journal-title":"J Am Med Inform Assoc"},{"key":"222_CR68","unstructured":"M. Howard und S. Lipner. The security development lifecycle: SDL, a process for developing demonstrably more secure software. Microsoft Press; 2006. ISBN-10: 0735622140"},{"key":"222_CR69","unstructured":"International Organization for Standardization (ISO): Information technology - security techniques - information security management systems - overview and vocabulary. ISO\/IEC 27000:2009(E). 2009."},{"key":"222_CR70","doi-asserted-by":"crossref","unstructured":"Shirey R. RFC4949: Internet security glossary (V2). 2007. https:\/\/tools.ietf.org\/html\/rfc4949 Accessed 28 September 2015.","DOI":"10.17487\/rfc4949"},{"key":"222_CR71","doi-asserted-by":"crossref","unstructured":"Majchrzak T, Schmitt O. Improving epidemiology research with patient registries based on advanced web technology. In: Proc Int Conf Info Sys Crisis Response Management. 2012:1\u20135.","DOI":"10.4018\/ijiscram.2013070104"},{"issue":"2","key":"222_CR72","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1267\/METH03020148","volume":"42","author":"GJE Moor De","year":"2003","unstructured":"De Moor GJE, Claerhout B, De Meyer F. Privacy enhancing techniques: the key to secure communication and management of clinical and genomic data. Methods Inf Med. 2003;42(2):148\u201353. doi: 10.1267\/METH03020148 .","journal-title":"Methods Inf Med"},{"key":"222_CR73","doi-asserted-by":"publisher","first-page":"170","DOI":"10.3233\/978-1-60750-939-4-170","volume":"95","author":"B Claerhout","year":"2002","unstructured":"Claerhout B, De Moor GJE, De Meyer F. Secure communication and management of clinical and genomic data: the use of pseudonymisation as privacy enhancing technique. Stud Health Technol Inform. 2002;95:170\u20135. doi: 10.3233\/978-1-60750-939-4-170 .","journal-title":"Stud Health Technol Inform"},{"issue":"1","key":"222_CR74","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/S0020-7101(96)01232-9","volume":"43","author":"K Iversen","year":"1996","unstructured":"Iversen K, Gr\u00f8tan T. Socio-technical aspects of the use of health related personal information for management and research. Int J Biomed Comput. 1996;43(1):83\u201391.","journal-title":"Int J Biomed Comput"},{"issue":"3","key":"222_CR75","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/S0167-7799(02)00039-2","volume":"21","author":"JE Wylie","year":"2003","unstructured":"Wylie JE, Mineau GP. Biomedical databases: protecting privacy and promoting research. Trends Biotechnol. 2003;21(3):113\u20136. doi: 10.1016\/S0167-7799(02)00039-2 .","journal-title":"Trends Biotechnol"},{"issue":"3","key":"222_CR76","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1007\/s10278-006-1051-4","volume":"20","author":"R Noumeir","year":"2007","unstructured":"Noumeir R, Lemay A, Lina JM. Pseudonymization of radiology data for research purposes. J Digit Imaging. 2007;20(3):284\u201395. doi: 10.1007\/s10278-006-1051-4 .","journal-title":"J Digit Imaging"},{"key":"222_CR77","first-page":"239","volume":"126","author":"IL Lo","year":"2007","unstructured":"Lo IL. Multi-centric universal pseudonymisation for secondary use of the EHR. Stud Health Technol Inform. 2007;126:239\u201347.","journal-title":"Stud Health Technol Inform"},{"key":"222_CR78","doi-asserted-by":"publisher","unstructured":"Heurix J, Karlinger M, Neubauer T. Pseudonymization with metadata encryption for privacy-preserving searchable documents. In: Proc Annu Hawaii Int Conf Syst Sci. HICSS 2012. 2012:3011\u20133020; doi: 10.1109\/HICSS.2012.491 .","DOI":"10.1109\/HICSS.2012.491"},{"issue":"3","key":"222_CR79","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1016\/j.ijmedinf.2010.10.016","volume":"80","author":"T Neubauer","year":"2011","unstructured":"Neubauer T, Heurix J. A methodology for the pseudonymization of medical data. Int J Med Inform. 2011;80(3):190\u2013204. doi: 10.1016\/j.ijmedinf.2010.10.016 .","journal-title":"Int J Med Inform"},{"issue":"2","key":"222_CR80","doi-asserted-by":"publisher","first-page":"23","DOI":"10.4304\/jsw.3.2.23-32","volume":"3","author":"B Riedl","year":"2008","unstructured":"Riedl B, Grascher V, Neubauer T. A secure e-health architecture based on the appliance of pseudonymization. J Software. 2008;3(2):23\u201332. doi: 10.4304\/jsw.3.2.23-32 .","journal-title":"J Software"},{"key":"222_CR81","unstructured":"Starlims: http:\/\/www.starlims.com\/de-de\/home (2015). Accessed 28 September 2015."},{"key":"222_CR82","unstructured":"secuTrial: http:\/\/www.secutrial.com (2015). Accessed 28 September 2015."},{"key":"222_CR83","unstructured":"DSLib: http:\/\/www.unimedizin-mainz.de\/imbei\/informatik\/opensource\/dslib.html (2015). Accessed 28 September 2015."},{"key":"222_CR84","doi-asserted-by":"crossref","unstructured":"Muscholl M, Lablans M, \u00dcckert F. OSSE: open source registry system for rare diseases in the EU (executive summary). 2014. http:\/\/download.osse-register.de\/OSSE_Executive_Summary.pdf . Accessed 30 November 2015.","DOI":"10.1186\/1750-1172-9-S1-O9"},{"key":"222_CR85","doi-asserted-by":"publisher","unstructured":"Muscholl M, Lablans M, Wagner TO, \u00dcckert F. OSSE: open source registry software solution. Orphanet J Rare Dis. 2014; 9 Suppl 1; doi: 10.1186\/1750-1172-9-S1-O9 .","DOI":"10.1186\/1750-1172-9-S1-O9"}],"container-title":["BMC Medical Informatics and Decision Making"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12911-015-0222-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12911-015-0222-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12911-015-0222-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,12]],"date-time":"2020-09-12T02:38:21Z","timestamp":1599878301000},"score":1,"resource":{"primary":{"URL":"http:\/\/bmcmedinformdecismak.biomedcentral.com\/articles\/10.1186\/s12911-015-0222-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11,30]]},"references-count":85,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["222"],"URL":"https:\/\/doi.org\/10.1186\/s12911-015-0222-y","relation":{},"ISSN":["1472-6947"],"issn-type":[{"value":"1472-6947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,11,30]]},"article-number":"100"}}