{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T12:27:35Z","timestamp":1765888055491,"version":"3.37.3"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,10,5]],"date-time":"2018-10-05T00:00:00Z","timestamp":1538697600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1054146"],"award-info":[{"award-number":["1054146"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Med Inform Decis Mak"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1186\/s12911-018-0666-y","type":"journal-article","created":{"date-parts":[[2018,10,5]],"date-time":"2018-10-05T08:16:36Z","timestamp":1538727396000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Reliability, ease of use and usefulness of I-MeDeSA for evaluating drug-drug interaction alerts in an Australian context"],"prefix":"10.1186","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1645-9126","authenticated-orcid":false,"given":"Melissa T","family":"Baysari","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Lowenstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wu Yi","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard O","family":"Day","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,10,5]]},"reference":[{"issue":"2","key":"666_CR1","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1111\/j.1365-2125.2009.03443.x","volume":"68","author":"J Zwart-van Rijkom","year":"2009","unstructured":"Zwart-van Rijkom J, Uijtendaal E, ten Berg M, van Solinge W, Egberts A. Frequency and nature of drug-drug interactions in a Dutch univeristy hospital. Br J Clin Pharmacol. 2009;68(2):187\u201393.","journal-title":"Br J Clin Pharmacol"},{"issue":"8","key":"666_CR2","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1007\/s00228-003-0684-1","volume":"59","author":"L Gu\u00e9don-Moreau","year":"2003","unstructured":"Gu\u00e9don-Moreau L, Ducrocq D, Duc M-F, Quieureux Y, L\u2019H\u00f4te C, Deligne J, Caron J. Absolute contraindications in relation to potential drug interactions in outpatient prescriptions: analysis of the first five million prescriptions in 1999. Eur J Clin Pharmacol. 2003;59(8):689\u201395.","journal-title":"Eur J Clin Pharmacol"},{"issue":"7456","key":"666_CR3","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1136\/bmj.329.7456.15","volume":"329","author":"M Pirmohamed","year":"2004","unstructured":"Pirmohamed M, James S, Meakin S, Green C, Scott AK, Walley TJ, Farrar K, Park BK, Breckenridge AM. Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients. BMJ (Clinical research ed). 2004;329(7456):15\u20139.","journal-title":"BMJ (Clinical research ed)"},{"issue":"8","key":"666_CR4","doi-asserted-by":"publisher","first-page":"667","DOI":"10.2165\/11534400-000000000-00000","volume":"33","author":"R Leone","year":"2010","unstructured":"Leone R, Magro L, Moretti U, Cutroneo P, Moschini M, Motola D, Tuccori M, Conforti A. Identifying adverse drug reactions associated with drug-drug interactions. Drug Saf. 2010;33(8):667\u201375.","journal-title":"Drug Saf"},{"issue":"5","key":"666_CR5","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1002\/pds.3592","volume":"23","author":"S Dechanont","year":"2014","unstructured":"Dechanont S, Maphanta S, Butthum B, Kongkaew C. Hospital admissions\/visits associated with drug-drug interactions: a systematic review and meta-analysis. Pharmacoepidemiol Drug Saf. 2014;23(5):489\u201397.","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"666_CR6","doi-asserted-by":"publisher","first-page":"525","DOI":"10.2165\/00002018-200831060-00007","volume":"31","author":"Y Ko","year":"2008","unstructured":"Ko Y, Malone D, Skrepnek G. Prescribers\u2019 knowledge of and sources of information for potential drug-drug interactions; a postal survey of US prescribers. Drug Saf. 2008;31:525\u201336.","journal-title":"Drug Saf"},{"issue":"1","key":"666_CR7","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1001\/jama.1995.03530010043033","volume":"274","author":"DW Bates","year":"1995","unstructured":"Bates DW, Cullen DJ, Laird N, et al. Incidence of adverse drug events and potential adverse drug events: implications for prevention. JAMA. 1995;274(1):29\u201334.","journal-title":"JAMA"},{"key":"666_CR8","unstructured":"Payne TH, Nichol WP, Hoey P, Savarino J. Characteristics and override rates of order checks in a practitioner order entry system. Proceedings of the AMIA Symposium. 2002:602\u20136."},{"issue":"16","key":"666_CR9","doi-asserted-by":"publisher","first-page":"1465","DOI":"10.1001\/archinternmed.2009.252","volume":"169","author":"SN Weingart","year":"2009","unstructured":"Weingart SN, Simchowitz B, Padolsky H, et al. AN empirical model to estimate the potential impact of medication safety alerts on patient safety, health care utilization, and cost in ambulatory care. Arch Intern Med. 2009;169(16):1465\u201373.","journal-title":"Arch Intern Med"},{"issue":"1","key":"666_CR10","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1197\/jamia.M2170","volume":"14","author":"GJ Kuperman","year":"2007","unstructured":"Kuperman GJ, Bobb A, Payne TH, Avery AJ, Gandhi TK, Burns G, Classen DC, Bates DW. Medication-related clinical decision support in computerized provider order entry systems: a review. J Am Med Inform Assoc. 2007;14(1):29\u201340.","journal-title":"J Am Med Inform Assoc"},{"issue":"2","key":"666_CR11","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1197\/jamia.M1809","volume":"13","author":"H van der Sijs","year":"2006","unstructured":"van der Sijs H, Aarts J, Vulto A, Berg M. Overriding of drug safety alerts in computerized physician order entry. J Am Med Inform Assoc. 2006;13(2):138\u201347.","journal-title":"J Am Med Inform Assoc"},{"issue":"12","key":"666_CR12","doi-asserted-by":"publisher","first-page":"1161","DOI":"10.1097\/00005650-200212000-00004","volume":"40","author":"PA Glassman","year":"2002","unstructured":"Glassman PA, Simon B, Belperio P, Lanto A. Improving recognition of drug interactions: benefits and barriers to using automated drug alerts. Med Care. 2002;40(12):1161\u201371.","journal-title":"Med Care"},{"issue":"11\u201312","key":"666_CR13","doi-asserted-by":"publisher","first-page":"676","DOI":"10.5694\/mja11.10206","volume":"195","author":"KH Yu","year":"2011","unstructured":"Yu KH, Sweidan M, Williamson M, Fraser A. Drug interaction alerts in software\u2014what do general practitioners and pharmacists want? Med J Aust. 2011;195(11\u201312):676\u201380.","journal-title":"Med J Aust"},{"issue":"1","key":"666_CR14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1472-6947-13-1","volume":"13","author":"JJ Coleman","year":"2013","unstructured":"Coleman JJ, van der Sijs H, Haefeli WE, Slight SP, McDowell SE, Seidling HM, Eiermann B, Aarts J, Ammenwerth E, Ferner RE, et al. On the alert: future priorities for alerts in clinical decision support for computerized physician order entry identified from a European workshop. BMC Med Inform Decis Mak. 2013;13(1):1\u20138.","journal-title":"BMC Med Inform Decis Mak"},{"issue":"6","key":"666_CR15","doi-asserted-by":"publisher","first-page":"1243","DOI":"10.1093\/jamia\/ocv011","volume":"22","author":"TH Payne","year":"2015","unstructured":"Payne TH, Hines LE, Chan RC, Hartman S, Kapusnik-Uner J, Russ AL, Chaffee BW, Hartman C, Tamis V, Galbreth B, et al. Recommendations to improve the usability of drug-drug interaction clinical decision support alerts. J Am Med Inform Assoc. 2015;22(6):1243\u201350.","journal-title":"J Am Med Inform Assoc"},{"issue":"5","key":"666_CR16","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1136\/jamia.2010.005264","volume":"17","author":"S Phansalkar","year":"2010","unstructured":"Phansalkar S, Edworthy J, Hellier E, Seger DL, Schedlbauer A, Avery AJ, Bates DW. A review of human factors principles for the design and implementation of medication safety alerts in clinical information systems. J Am Med Inform Assoc. 2010;17(5):493\u2013501.","journal-title":"J Am Med Inform Assoc"},{"issue":"4","key":"666_CR17","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1136\/amiajnl-2010-000039","volume":"18","author":"HM Seidling","year":"2011","unstructured":"Seidling HM, Phansalkar S, Seger DL, Paterno MD, Shaykevich S, Haefeli WE, Bates DW. Factors influencing alert acceptance: a novel approach for predicting the success of clinical decision support. J Am Med Inform Assoc. 2011;18(4):479\u201384.","journal-title":"J Am Med Inform Assoc"},{"issue":"Supplement 1","key":"666_CR18","doi-asserted-by":"publisher","first-page":"i62","DOI":"10.1136\/amiajnl-2011-000362","volume":"18","author":"M Zachariah","year":"2011","unstructured":"Zachariah M, Phansalkar S, Seidling HM, Neri PM, Cresswell KM, Duke J, Bloomrosen M, Volk LA, Bates DW. Development and preliminary evidence for the validity of an instrument assessing implementation of human-factors principles in medication-related decision-support systems\u2014I-MeDeSA. J Am Med Inform Assoc. 2011;18(Supplement 1):i62\u201372.","journal-title":"J Am Med Inform Assoc"},{"issue":"e2","key":"666_CR19","doi-asserted-by":"publisher","first-page":"e332","DOI":"10.1136\/amiajnl-2013-002279","volume":"21","author":"S Phansalkar","year":"2014","unstructured":"Phansalkar S, Zachariah M, Seidling HM, Mendes C, Volk L, Bates DW. Evaluation of medication alerts in electronic health records for compliance with human factors principles. J Am Med Inform Assoc. 2014;21(e2):e332\u201340.","journal-title":"J Am Med Inform Assoc"},{"issue":"2","key":"666_CR20","doi-asserted-by":"publisher","first-page":"571","DOI":"10.4338\/ACI-2014-01-RA-0005","volume":"5","author":"I Cho","year":"2014","unstructured":"Cho I, Lee J, Han H, Phansalkar S, Bates DW. Evaluation of a Korean version of a tool for assessing the incorporation of human factors into a medication-related decision support system: the I-MeDeSA. Appl Clin Inform. 2014;5(2):571\u201388.","journal-title":"Appl Clin Inform"},{"key":"666_CR21","first-page":"754","volume":"18","author":"MT Baysari","year":"2011","unstructured":"Baysari MT, Westbrook JI, Richardson KL, Day RO. The influence of computerized decision support on prescribing during ward-rounds: are the decision-makers targeted? JAMIA. 2011;18:754\u20139.","journal-title":"JAMIA"},{"key":"666_CR22","doi-asserted-by":"crossref","unstructured":"Iarossi G. The power of survey design: A User\u2019s Guide for Managing Surveys, Interpeting Results and Influencing Respondents: World Bank Publications; 2006.","DOI":"10.1596\/978-0-8213-6392-8"}],"container-title":["BMC Medical Informatics and Decision Making"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12911-018-0666-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12911-018-0666-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12911-018-0666-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,4]],"date-time":"2019-10-04T19:05:49Z","timestamp":1570215949000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcmedinformdecismak.biomedcentral.com\/articles\/10.1186\/s12911-018-0666-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,5]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["666"],"URL":"https:\/\/doi.org\/10.1186\/s12911-018-0666-y","relation":{},"ISSN":["1472-6947"],"issn-type":[{"type":"electronic","value":"1472-6947"}],"subject":[],"published":{"date-parts":[[2018,10,5]]},"assertion":[{"value":"17 May 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 September 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 October 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Ethics approval was obtained from Macquarie University\u2019s Human Research Ethics Committee (#5201600140), St Vincent\u2019s Hospital Human Research Ethics Committee (LNR\/16\/SVH\/75) and Concord Repatriation General Hospital\u2019s Research Governance Committee (2016\u2013132).","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"As this study involved no participants, consent for publication is not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"83"}}