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The Comit\u00e9 de \u00c9tica de la Investigaci\u00f3n Cl\u00ednica con Medicamentos (CEIm) of the Hospital 12 de Octubre (Madrid, Spain) approved this work with registration number 19\/434. Written informed consent in accordance with the recommendations of the Declaration of Human Rights, the Conference of Helsinki, and institutional regulations were obtained from all patients.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable\u2014no individual details, images or videos were used in this work.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"179"}}