{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T05:34:43Z","timestamp":1769060083013,"version":"3.49.0"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:00:00Z","timestamp":1761004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:00:00Z","timestamp":1761004800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"NIH","award":["K99LM014097"],"award-info":[{"award-number":["K99LM014097"]}]},{"name":"NIH","award":["R01AG062499"],"award-info":[{"award-number":["R01AG062499"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Med Inform Decis Mak"],"DOI":"10.1186\/s12911-025-03231-0","type":"journal-article","created":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T11:26:36Z","timestamp":1761045996000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A standard-based taxonomy of features that affect user response to clinical decision support alerts"],"prefix":"10.1186","volume":"25","author":[{"given":"Siru","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allison B.","family":"McCoy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dean F.","family":"Sittig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josh F.","family":"Peterson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas A.","family":"Lasko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam","family":"Wright","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,10,21]]},"reference":[{"issue":"3","key":"3231_CR2","doi-asserted-by":"publisher","first-page":"331","DOI":"10.4338\/ACI-2010-05-RA-0031","volume":"1","author":"A Wright","year":"2010","unstructured":"Wright A, Phansalkar S, Bloomrosen M, Jenders RA, Bobb AM, Halamka JD, et al. Best practices in clinical decision support: the case of preventive care reminders. Appl Clin Inf. 2010;1(3):331.","journal-title":"Appl Clin Inf"},{"issue":"3","key":"3231_CR3","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1001\/archinternmed.2008.551","volume":"169","author":"T Isaac","year":"2009","unstructured":"Isaac T, Weissman JS, Davis RB, Massagli M, Cyrulik A, Sands DZ, et al. Overrides of medication alerts in ambulatory care. Arch Intern Med. 2009;169(3):305\u201311.","journal-title":"Arch Intern Med"},{"issue":"3","key":"3231_CR4","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1136\/amiajnl-2013-001813","volume":"21","author":"KC Nanji","year":"2014","unstructured":"Nanji KC, Slight SP, Seger DL, Cho I, Fiskio JM, Redden LM, et al. Overrides of medication-related clinical decision support alerts in outpatients. J Am Med Inform Assoc. 2014;21(3):487\u201391.","journal-title":"J Am Med Inform Assoc"},{"issue":"July","key":"3231_CR5","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/j.ijmedinf.2017.08.008","volume":"107","author":"Y Zenziper Straichman","year":"2017","unstructured":"Zenziper Straichman Y, Kurnik D, Matok I, Halkin H, Markovits N, Ziv A, et al. Prescriber response to computerized drug alerts for electronic prescriptions among hospitalized patients. Int J Med Inf. 2017;107(July):70\u20135.","journal-title":"Int J Med Inf"},{"key":"3231_CR6","doi-asserted-by":"publisher","unstructured":"Ancker JS, Edwards A, Nosal S, Hauser D, Mauer E, Kaushal R. Effects of workload, work complexity, and repeated alerts on alert fatigue in a clinical decision support system. BMC Med Inform Decis Mak. 2017 Dec 10;17(1):36. Available from: http:\/\/bmcmedinformdecismak.biomedcentral.com\/articles\/https:\/\/doi.org\/10.1186\/s12911-017-0430-8","DOI":"10.1186\/s12911-017-0430-8"},{"key":"3231_CR7","doi-asserted-by":"crossref","unstructured":"Wright A, Aaron S, Seger DL, Samal L, Schiff GD, Bates DW. Reduced effectiveness of interruptive drug-drug interaction alerts after conversion to a commercial electronic health record. J Gen Intern Med. 2018 Nov 1 [cited 2023 Oct 8];33(11):1868\u201376. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/29766382\/","DOI":"10.1007\/s11606-018-4415-9"},{"issue":"13","key":"3231_CR8","doi-asserted-by":"publisher","first-page":"1086","DOI":"10.1093\/ajhp\/zxac045","volume":"79","author":"T Reese","year":"2022","unstructured":"Reese T, Wright A, Liu S, Boyce R, Romero A, Del Fiol G, et al. Improving the specificity of drug-drug interaction alerts: can it be done? Am J Health Syst Pharm. 2022;79(13):1086\u201395.","journal-title":"Am J Health Syst Pharm"},{"key":"3231_CR9","doi-asserted-by":"publisher","unstructured":"Liu S, McCoy AB, Peterson JF, Lasko TA, Sittig DF, Nelson SD et al. Leveraging explainable artificial intelligence to optimize clinical decision support. J Am Med Inform Assoc. 2024 Apr 3;31(4):968\u201374. Available from: https:\/\/doi.org\/10.1093\/jamia\/ocae019","DOI":"10.1093\/jamia\/ocae019"},{"key":"3231_CR10","doi-asserted-by":"publisher","unstructured":"Liu S, Wright AP, Patterson BL, Wanderer JP, Turer RW, Nelson SD et al. Using AI-generated suggestions from ChatGPT to optimize clinical decision support. J Am Med Inform Assoc. 2023 Jun 20;30(7):1237\u201345. Available from: https:\/\/academic.oup.com\/jamia\/advance-article\/doi\/https:\/\/doi.org\/10.1093\/jamia\/ocad072\/7136722","DOI":"10.1093\/jamia\/ocad072\/7136722"},{"issue":"5","key":"3231_CR11","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1093\/jamia\/ocab292","volume":"29","author":"S Liu","year":"2022","unstructured":"Liu S, Kawamoto K, Del Fiol G, Weir C, Malone DC, Reese TJ, et al. The potential for leveraging machine learning to filter medication alerts. J Am Med Inform Assoc. 2022;29(5):891\u20139.","journal-title":"J Am Med Inform Assoc"},{"key":"3231_CR12","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1186\/1472-6947-11-35","volume":"11","author":"D Riedmann","year":"2011","unstructured":"Riedmann D, Jung M, Hackl WO, St\u00fchlinger W, van der Sijs H, Ammenwerth E. Development of a context model to prioritize drug safety alerts in CPOE systems. BMC Med Inf Decis Mak. 2011;11:35.","journal-title":"BMC Med Inf Decis Mak"},{"key":"3231_CR13","first-page":"920","volume":"169","author":"E Ammenwerth","year":"2011","unstructured":"Ammenwerth E, Hackl WO, Riedmann D, Jung M. Contextualization of automatic alerts during electronic prescription: researchers\u2019 and users\u2019 opinions on useful context factors. Stud Health Technol Inform. 2011;169:920\u20134.","journal-title":"Stud Health Technol Inform"},{"issue":"1","key":"3231_CR14","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1186\/1472-6947-12-111","volume":"12","author":"M Jung","year":"2012","unstructured":"Jung M, Riedmann D, Hackl WO, Hoerbst A, Jaspers MW, Ferret L, et al. Physicians\u2019 perceptions on the usefulness of contextual information for prioritizing and presenting alerts in computerized physician order entry systems. BMC Med Inf Decis Mak. 2012;12(1):111.","journal-title":"BMC Med Inf Decis Mak"},{"issue":"1","key":"3231_CR15","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1186\/s12911-021-01465-2","volume":"21","author":"S Liu","year":"2021","unstructured":"Liu S, Reese TJ, Kawamoto K, Fiol G, Del, Weir C, Del Fiol G, et al. A systematic review of theoretical constructs in CDS literature. BMC Med Inf Decis Mak. 2021;21(1):102.","journal-title":"BMC Med Inf Decis Mak"},{"key":"3231_CR16","doi-asserted-by":"crossref","unstructured":"Liu S, Reese TJ, Kawamoto K, Del Fiol G, Weir C. Toward Optimized Clinical Decision Support: A Theory-Based Approach. In: 2020 IEEE International Conference on Healthcare Informatics (ICHI). IEEE; 2020. pp. 1\u20132.","DOI":"10.1109\/ICHI48887.2020.9374346"},{"issue":"11","key":"3231_CR17","doi-asserted-by":"publisher","first-page":"2514","DOI":"10.1093\/jamia\/ocab160","volume":"28","author":"S Liu","year":"2021","unstructured":"Liu S, Reese TJ, Kawamoto K, Del Fiol G, Weir C. A theory-based meta-regression of factors influencing clinical decision support adoption and implementation. J Am Med Inform Assoc. 2021;28(11):2514\u201322.","journal-title":"J Am Med Inform Assoc"},{"key":"3231_CR18","unstructured":"Health Level 7. FHIR v5.0.0: R5 [Internet]. [cited 2020 Dec 30]. Available from: https:\/\/www.hl7.org\/fhir\/"},{"issue":"1","key":"3231_CR19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12911-016-0389-x","volume":"17","author":"A Boussadi","year":"2017","unstructured":"Boussadi A, Zapletal E. A fast healthcare interoperability resources (FHIR) layer implemented over i2b2. BMC Med Inf Decis Mak. 2017;17(1):1\u201312.","journal-title":"BMC Med Inf Decis Mak"},{"key":"3231_CR20","doi-asserted-by":"publisher","first-page":"15","DOI":"10.4324\/9781498757461","volume-title":"Improving outcomes with clinical decision support: an implementer\u2019s Guide. 2nd Editio. Improving outcomes with clinical decision support","author":"J Osheroff","year":"2012","unstructured":"Osheroff J. Improving outcomes with clinical decision support: an implementer\u2019s Guide. 2nd Editio. Improving outcomes with clinical decision support. Chicago: HIMSS Publishing; 2012. p. 15."}],"container-title":["BMC Medical Informatics and Decision Making"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12911-025-03231-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12911-025-03231-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12911-025-03231-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T00:03:36Z","timestamp":1761091416000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcmedinformdecismak.biomedcentral.com\/articles\/10.1186\/s12911-025-03231-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,21]]},"references-count":19,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["3231"],"URL":"https:\/\/doi.org\/10.1186\/s12911-025-03231-0","relation":{},"ISSN":["1472-6947"],"issn-type":[{"value":"1472-6947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,21]]},"assertion":[{"value":"23 December 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 September 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 October 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"389"}}