{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T13:09:52Z","timestamp":1722431392915},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"S1","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Syst Biol"],"published-print":{"date-parts":[[2019,3]]},"DOI":"10.1186\/s12918-019-0685-z","type":"journal-article","created":{"date-parts":[[2019,3,5]],"date-time":"2019-03-05T10:05:38Z","timestamp":1551780338000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Systems biology research at BGRS-2018"],"prefix":"10.1186","volume":"13","author":[{"given":"Yuriy L.","family":"Orlov","sequence":"first","affiliation":[]},{"given":"Ralf","family":"Hofest\u00e4dt","sequence":"additional","affiliation":[]},{"given":"Ancha V.","family":"Baranova","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2019,3,5]]},"reference":[{"issue":"Suppl 14","key":"685_CR1","doi-asserted-by":"publisher","first-page":"996","DOI":"10.1186\/s12864-016-3350-6","volume":"17","author":"YL Orlov","year":"2016","unstructured":"Orlov YL, Baranova AV, Hofestadt R, Kolchanov NA. Computational genomics at BGRS\\SB-2016: introductory note. BMC Genomics. 2016;17(Suppl 14):996.","journal-title":"BMC Genomics"},{"issue":"Suppl 3","key":"685_CR2","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1186\/s12870-016-0923-0","volume":"16","author":"YL Orlov","year":"2016","unstructured":"Orlov YL, Baranova AV, Salina EA. Computational plant bioscience at BGRS\\SB-2016: introductory note. BMC Plant Biol. 2016;16(Suppl 3):243.","journal-title":"BMC Plant Biol"},{"issue":"Suppl 3","key":"685_CR3","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1186\/s12863-016-0465-3","volume":"17","author":"YL Orlov","year":"2016","unstructured":"Orlov YL, Baranova AV, Markel AL. Computational models in genetics at BGRS\\SB-2016: introductory note. BMC Genet. 2016;17(Suppl 3):155.","journal-title":"BMC Genet"},{"key":"685_CR4","doi-asserted-by":"publisher","unstructured":"Orlov YL, Baranova AV, Kolchanov NA, Moroz LL. Evolutionary biology research at BGRS-2018. BMC Evol Biol. 2019;19(Suppl 1). \n                    https:\/\/doi.org\/10.1186\/s12862-019-1368-5","DOI":"10.1186\/s12862-019-1368-5"},{"key":"685_CR5","doi-asserted-by":"crossref","unstructured":"Orlov YL, Fernandez-Masso JR, Chen M, Baranova AV. Medical genomics at Belyaev Conference - 2017. BMC Med Genomics. 2018;11(Suppl 1):11.","DOI":"10.1186\/s12920-018-0324-3"},{"key":"685_CR6","doi-asserted-by":"crossref","unstructured":"Orlov YL, Moroz LL, Baranova AV. Neuroscience researches at Belyaev conference-2017. BMC Neurosci. 2018;19(Suppl 1):14.","DOI":"10.1186\/s12868-018-0410-7"},{"issue":"Suppl 1","key":"685_CR7","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1186\/s12863-017-0577-4","volume":"18","author":"YL Orlov","year":"2017","unstructured":"Orlov YL, Baranova AV, Tatarinova TV, Kolchanov NA. Genetics at Belyaev conference - 2017: introductory note. BMC Genet. 2017;18(Suppl 1):116.","journal-title":"BMC Genet"},{"issue":"Suppl 2","key":"685_CR8","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1186\/s12870-017-1189-x","volume":"17","author":"YL Orlov","year":"2017","unstructured":"Orlov YL, Baranova AV, Chen M, Salina EA. Plant biology at Belyaev conference - 2017. BMC Plant Biol. 2017;17(Suppl 2):257.","journal-title":"BMC Plant Biol"},{"key":"685_CR9","doi-asserted-by":"publisher","unstructured":"Sakharov DA, Maltseva DV, Knyazev EN, Nikulin SV, Poloznikov AA, Shilin SA, Baranova A, Tsypina IM, Tonevitsky AG. Towards embedding Caco-2 model of gut interface 2 in a microfluidic device to enable multi-organ models for systems biology. BMC Syst Biol. 2019;13(Suppl 1). \n                    https:\/\/doi.org\/10.1186\/s12918-019-0686-y\n                    \n                  .","DOI":"10.1186\/s12918-019-0686-y"},{"key":"685_CR10","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1016\/j.jbiotec.2015.02.002","volume":"205","author":"EM Materne","year":"2015","unstructured":"Materne EM, Ramme AP, Terrasso AP, Serra M, Alves PM, Brito C, Sakharov DA, Tonevitsky AG, Lauster R, Marx U. A multi-organ chip co-culture of neurospheres and liver equivalents for long-term substance testing. J Biotechnol. 2015;205:36\u201346.","journal-title":"J Biotechnol"},{"issue":"3","key":"685_CR11","doi-asserted-by":"publisher","first-page":"397","DOI":"10.14573\/altex.1803221","volume":"35","author":"A Poloznikov","year":"2018","unstructured":"Poloznikov A, Gazaryan I, Shkurnikov M, Nikulin S, Drapkina O, Baranova A, Tonevitsky A. In vitro and in silico liver models: current trends, challenges and opportunities. ALTEX. 2018;35(3):397\u2013412.","journal-title":"ALTEX"},{"key":"685_CR12","doi-asserted-by":"publisher","unstructured":"Moskalev A, Proshkina E, Zhavoronkov A, Shaposhnikov M. Effects of unpaired 1 gene overexpression on the lifespan of Drosophila melanogaster. BMC Syst Biol. 2019;13(Suppl 1). \n                    https:\/\/doi.org\/10.1186\/s12918-019-0687-x\n                    \n                  .","DOI":"10.1186\/s12918-019-0687-x"},{"key":"685_CR13","doi-asserted-by":"publisher","unstructured":"Pastushkova LH, Rusanov VB, Goncharova AG, Brzhozovskiy AG, Kononikhin AS, Chernikova AG, Kashirina DN, Nosovsky AM, Baevsky RM, Nikolaev EN, Larina IM. Urine proteome changes associated with autonomic regulation of heart rate in cosmonauts. BMC Systems Biol. 2019;13(Suppl 1). \n                    https:\/\/doi.org\/10.1186\/s12918-019-0688-9\n                    \n                  .","DOI":"10.1186\/s12918-019-0688-9"},{"issue":"4","key":"685_CR14","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1177\/1469066717717610","volume":"23","author":"A Brzhozovskiy","year":"2017","unstructured":"Brzhozovskiy A, Kononikhin A, Indeykina M, Pastushkova L, Popov IA, Nikolaev EN, Larina IM. Label-free study of cosmonaut's urinary proteome changes after long-duration spaceflights. Eur J Mass Spectrom (Chichester). 2017;23(4):225\u20139.","journal-title":"Eur J Mass Spectrom (Chichester)"},{"issue":"1","key":"685_CR15","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1080\/14789450.2017.1258307","volume":"14","author":"AS Kononikhin","year":"2017","unstructured":"Kononikhin AS, Starodubtseva NL, Pastushkova LK, Kashirina DN, Fedorchenko KY, Brhozovsky AG, Popov IA, Larina IM, Nikolaev EN. Spaceflight induced changes in the human proteome. Expert Rev Proteomics. 2017;14(1):15\u201329.","journal-title":"Expert Rev Proteomics"},{"key":"685_CR16","doi-asserted-by":"publisher","unstructured":"Zubairova US, Verman PY, Oshchepkova PA, Elsukova AS, Doroshklov AV. LSM-W2: laser scanning microscopy worker for wheat leaf surface morphology. BMC Systems Biol. 2019;13(Suppl 1). \n                    https:\/\/doi.org\/10.1186\/s12918-019-0689-8\n                    \n                  .","DOI":"10.1186\/s12918-019-0689-8"}],"container-title":["BMC Systems Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12918-019-0685-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12918-019-0685-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12918-019-0685-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,3,4]],"date-time":"2020-03-04T00:20:36Z","timestamp":1583281236000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcsystbiol.biomedcentral.com\/articles\/10.1186\/s12918-019-0685-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3]]},"references-count":16,"journal-issue":{"issue":"S1","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["685"],"URL":"https:\/\/doi.org\/10.1186\/s12918-019-0685-z","relation":{},"ISSN":["1752-0509"],"issn-type":[{"value":"1752-0509","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3]]},"assertion":[{"value":"5 March 2019","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Not applicable.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"21"}}