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The app was developed to make target information available to as large an audience as possible.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We now report a major update of the iOS version of the app. This includes enhancements that use an implementation of ECFP_6 fingerprints that we have made open source. Using these fingerprints, the user can propose compounds with possible anti-TB activity, and view the compounds within a cluster landscape. Proposed compounds can also be compared to existing target data, using a n\u00e4ive Bayesian scoring system to rank probable targets. We have curated an additional 60 new compounds and their targets for<jats:italic>Mtb<\/jats:italic>and added these to the original set of 745 compounds. We have also curated 20 further compounds (many without targets in TB Mobile) to evaluate this version of the app with 805 compounds and associated targets.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:italic>TB Mobile<\/jats:italic>can now manage a small collection of compounds that can be imported from external sources, or exported by various means such as email or app-to-app inter-process communication. This means that<jats:italic>TB Mobile<\/jats:italic>can be used as a node within a growing ecosystem of mobile apps for cheminformatics. It can also cluster compounds and use internal algorithms to help identify potential targets based on molecular similarity.<jats:italic>TB Mobile<\/jats:italic>represents a valuable dataset, data-visualization aid and target prediction tool.<\/jats:p><\/jats:sec>","DOI":"10.1186\/s13321-014-0038-2","type":"journal-article","created":{"date-parts":[[2014,8,2]],"date-time":"2014-08-02T22:03:58Z","timestamp":1407017038000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["New target prediction and visualization tools incorporating open source molecular fingerprints for TB Mobile 2.0"],"prefix":"10.1186","volume":"6","author":[{"given":"Alex M","family":"Clark","sequence":"first","affiliation":[]},{"given":"Malabika","family":"Sarker","sequence":"additional","affiliation":[]},{"given":"Sean","family":"Ekins","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2014,8,4]]},"reference":[{"key":"38_CR1","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1038\/nrd3368","volume":"10","author":"R Macarron","year":"2011","unstructured":"Macarron R, Banks MN, Bojanic D, Burns DJ, Cirovic DA, Garyantes T, Green DV, Hertzberg RP, Janzen WP, Paslay JW, Schopfer U, Sittampalam GS: Impact of high-throughput screening in biomedical research. 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