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To contrast these theoretical assumptions, this study aims to identify the level of training and technical knowledge of primary school teachers in Spain regarding the use of ICTs for supporting students with special needs. The research methodology used was a mixed research design (quantitative and qualitative method), analysing 777 questionnaires supplied to primary school teachers and 723 interviews conducted with key informants (members of management teams, ICT coordinators, directors and technological advisors of teacher training centres). The results informed teachers' knowledge about ICT and disability and barriers or obstacles to their training. 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