{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T13:05:29Z","timestamp":1772802329166,"version":"3.50.1"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2004,8,11]],"date-time":"2004-08-11T00:00:00Z","timestamp":1092182400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2004,8,11]],"date-time":"2004-08-11T00:00:00Z","timestamp":1092182400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arthritis Res Ther"],"DOI":"10.1186\/ar1213","type":"journal-article","created":{"date-parts":[[2004,8,12]],"date-time":"2004-08-12T06:23:11Z","timestamp":1092291791000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Antibodies against the CB10 fragment of type II collagen in rheumatoid arthritis"],"prefix":"10.1186","volume":"6","author":[{"given":"Andrew D","family":"Cook","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robyn","family":"Gray","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Ramshaw","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian R","family":"Mackay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Merrill J","family":"Rowley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2004,8,11]]},"reference":[{"key":"1201_CR1","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1111\/j.1600-065X.1990.tb00817.x","volume":"118","author":"R Holmdahl","year":"1990","unstructured":"Holmdahl R, Andersson M, Goldschmidt TJ, Gustafsson K, Jansson L, Mo JA: Type II collagen autoimmunity in animals and provocations leading to arthritis. Immunol Rev. 1990, 118: 193-232.","journal-title":"Immunol Rev"},{"key":"1201_CR2","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1002\/art.1780300418","volume":"30","author":"WC Watson","year":"1987","unstructured":"Watson WC, Brown PS, Pitcock JA, Townes AS: Passive transfer studies with type II collagen antibody in B10.D2\/old and new line and C57Bl\/6 normal and beige (Chediak\u2013Higashi) strains: evidence of important roles for C5 and multiple inflammatory cell types in the development of erosive arthritis. Arthritis Rheum. 1987, 30: 460-465.","journal-title":"Arthritis Rheum"},{"key":"1201_CR3","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1002\/anr.1780320906","volume":"32","author":"A Tarkowski","year":"1989","unstructured":"Tarkowski A, Klareskog L, Carlsten H, Herberts P, Koopman WJ: Secretion of antibodies to types I and II collagen by synovial tissue cells in patients with rheumatoid arthritis. Arthritis Rheum. 1989, 32: 1087-1092.","journal-title":"Arthritis Rheum"},{"key":"1201_CR4","doi-asserted-by":"publisher","first-page":"1409","DOI":"10.1002\/art.1780400808","volume":"40","author":"U Rudolphi","year":"1997","unstructured":"Rudolphi U, Rzepka R, Batsford S, Kaufmann SH, von der Mark K, Peter HH, Melchers I: The B cell repertoire of patients with rheumatoid arthritis. II. Increased frequencies of IgG+ and IgA+ B cells specific for mycobacterial heat-shock protein 60 or human type II collagen in synovial fluid and tissue. Arthritis Rheum. 1997, 40: 1409-1419.","journal-title":"Arthritis Rheum"},{"key":"1201_CR5","doi-asserted-by":"publisher","first-page":"902","DOI":"10.1136\/ard.46.12.902","volume":"46","author":"K Morgan","year":"1987","unstructured":"Morgan K, Clague RB, Collins I, Ayad S, Phinn SD, Holt PJ: Incidence of antibodies to native and denatured cartilage collagens (types II, IX, and XI) and to type I collagen in rheumatoid arthritis. Ann Rheum Dis. 1987, 46: 902-907.","journal-title":"Ann Rheum Dis"},{"key":"1201_CR6","doi-asserted-by":"publisher","first-page":"1493","DOI":"10.1002\/art.1780331006","volume":"33","author":"K Terato","year":"1990","unstructured":"Terato K, Shimozuru Y, Katayama K, Takemitsu Y, Yamashita I, Miyatsu M, Fujii K, Sagara M, Kobayashi S, Goto M, et al: Specificity of antibodies to type II collagen in rheumatoid arthritis. Arthritis Rheum. 1990, 33: 1493-1500.","journal-title":"Arthritis Rheum"},{"key":"1201_CR7","first-page":"2090","volume":"24","author":"AD Cook","year":"1997","unstructured":"Cook AD, Mackay IR, Cicuttini FM, Rowley MJ: IgG subclasses of antibodies to type II collagen in rheumatoid arthritis differ from those in systemic lupus erythematosus and other connective tissue diseases. J Rheumatol. 1997, 24: 2090-2096.","journal-title":"J Rheumatol"},{"key":"1201_CR8","doi-asserted-by":"publisher","first-page":"2569","DOI":"10.1002\/1529-0131(199912)42:12<2569::AID-ANR9>3.0.CO;2-3","volume":"42","author":"AD Cook","year":"1999","unstructured":"Cook AD, Stockman A, Brand CA, Tait BD, Mackay IR, Muirden KD, Bernard CC, Rowley MJ: Antibodies to type II collagen and HLA disease susceptibility markers in rheumatoid arthritis. Arthritis Rheum. 1999, 42: 2569-2576. 10.1002\/1529-0131(199912)42:12<2569::AID-ANR9>3.0.CO;2-3.","journal-title":"Arthritis Rheum"},{"key":"1201_CR9","doi-asserted-by":"publisher","first-page":"1363","DOI":"10.1002\/art.1780241105","volume":"24","author":"DE Trentham","year":"1981","unstructured":"Trentham DE, Kammer GM, McCune WJ, David JR: Autoimmunity to collagen: a shared feature of psoriatic and rheumatoid arthritis. Arthritis Rheum. 1981, 24: 1363-1369.","journal-title":"Arthritis Rheum"},{"key":"1201_CR10","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1136\/ard.47.4.313","volume":"47","author":"EK Choi","year":"1988","unstructured":"Choi EK, Gatenby PA, McGill NW, Bateman JF, Cole WG, York JR: Autoantibodies to type II collagen: occurrence in rheumatoid arthritis, other arthritides, autoimmune connective tissue diseases, and chronic inflammatory syndromes. Ann Rheum Dis. 1988, 47: 313-322.","journal-title":"Ann Rheum Dis"},{"key":"1201_CR11","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1002\/art.1780310303","volume":"31","author":"G Charriere","year":"1988","unstructured":"Charriere G, Hartmann DJ, Vignon E, Ronziere MC, Herbage D, Ville G: Antibodies to types I, II, IX, and XI collagen in the serum of patients with rheumatic diseases. Arthritis Rheum. 1988, 31: 325-332.","journal-title":"Arthritis Rheum"},{"key":"1201_CR12","first-page":"289","volume":"15","author":"MJ Rowley","year":"1988","unstructured":"Rowley MJ, Gershwin ME, Mackay IR: Collagen antibodies in juvenile arthritis and adult rheumatoid arthritis: differences in levels and type-specificity. J Rheumatol. 1988, 15: 289-294.","journal-title":"J Rheumatol"},{"key":"1201_CR13","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1038\/icb.1990.4","volume":"68","author":"EK Choi","year":"1990","unstructured":"Choi EK, Gatenby PA, Bateman JF, Cole WG: Antibodies to type II collagen in SLE: a role in the pathogenesis of deforming arthritis?. Immunol Cell Biol. 1990, 68: 27-31.","journal-title":"Immunol Cell Biol"},{"key":"1201_CR14","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1016\/S0140-6736(85)90436-2","volume":"2","author":"RS Pereira","year":"1985","unstructured":"Pereira RS, Black CM, Duance VC, Jones VE, Jacoby RK, Welsh KI: Disappearing collagen antibodies in rheumatoid arthritis. Lancet. 1985, 2: 501-502. 10.1016\/S0140-6736(85)90436-2.","journal-title":"Lancet"},{"key":"1201_CR15","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1007\/BF00182710","volume":"16","author":"K Fujii","year":"1992","unstructured":"Fujii K, Tsuji M, Kitamura A, Murota K: The diagnostic significance of anti-type II collagen antibody assay in rheumatoid arthritis. Int Orthop. 1992, 16: 272-276. 10.1007\/BF00182710.","journal-title":"Int Orthop"},{"key":"1201_CR16","first-page":"1186","volume":"21","author":"AD Cook","year":"1994","unstructured":"Cook AD, Rowley MJ, Stockman A, Muirden KD, Mackay IR: Specificity of antibodies to type II collagen in early rheumatoid arthritis. J Rheumatol. 1994, 21: 1186-1191.","journal-title":"J Rheumatol"},{"key":"1201_CR17","doi-asserted-by":"publisher","first-page":"1720","DOI":"10.1002\/art.1780391015","volume":"39","author":"AD Cook","year":"1996","unstructured":"Cook AD, Rowley MJ, Mackay IR, Gough A, Emery P: Antibodies to type II collagen in early rheumatoid arthritis. Correlation with disease progression. Arthritis Rheum. 1996, 39: 1720-1727.","journal-title":"Arthritis Rheum"},{"key":"1201_CR18","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1002\/art.1780310302","volume":"31","author":"FC Arnett","year":"1988","unstructured":"Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, Healey LA, Kaplan SR, Liang MH, Luthra HS, et al: The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 1988, 31: 315-324.","journal-title":"Arthritis Rheum"},{"key":"1201_CR19","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/S0198-8859(96)00204-2","volume":"51","author":"MA Sherritt","year":"1996","unstructured":"Sherritt MA, Tait B, Varney M, Kanaan C, Stockman A, Mackay IR, Muirden K, Bernard CC, Rowley MJ: Immunosusceptibility genes in rheumatoid arthritis. Hum Immunol. 1996, 51: 32-40. 10.1016\/S0198-8859(96)00204-2.","journal-title":"Hum Immunol"},{"key":"1201_CR20","doi-asserted-by":"publisher","first-page":"448","DOI":"10.3109\/03009749709065718","volume":"26","author":"MJ Rowley","year":"1997","unstructured":"Rowley MJ, Stockman A, Brand CA, Tait BD, Rowley GL, Sherritt MA, Mackay IR, Muirden KD, Bernard CC: The effect of HLA-DRB1 disease susceptibility markers on the expression of RA. Scand J Rheumatol. 1997, 26: 448-455.","journal-title":"Scand J Rheumatol"},{"key":"1201_CR21","doi-asserted-by":"publisher","first-page":"107","DOI":"10.3109\/03008207609152206","volume":"4","author":"PG Scott","year":"1976","unstructured":"Scott PG, Veis A: The cyanogen bromide peptides of bovine soluble and insoluble collagens. I. Characterization of peptides from soluble type I collagen by sodium dodecylsulphate polyacrylamide gel electrophoresis. Connect Tissue Res. 1976, 4: 107-116.","journal-title":"Connect Tissue Res"},{"key":"1201_CR22","doi-asserted-by":"publisher","first-page":"3153","DOI":"10.1021\/bi00741a003","volume":"12","author":"EJ Miller","year":"1973","unstructured":"Miller EJ, Lunde LG: Isolation and characterization of the cyanogen bromide peptides from the alpha 1(II) chain of bovine and human cartilage collagen. Biochemistry. 1973, 12: 3153-3159. 10.1021\/bi00741a003.","journal-title":"Biochemistry"},{"key":"1201_CR23","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1016\/S0174-173X(85)80001-7","volume":"5","author":"K Terato","year":"1985","unstructured":"Terato K, Cremer MA, Hasty KA, Kang AH, Hasty DL, Townes AS: Physicochemical and immunological studies of the renatured alpha 1(II) chains and isolated cyanogen bromide peptides of type II collagen. Collagen Relat Res. 1985, 5: 469-480.","journal-title":"Collagen Relat Res"},{"key":"1201_CR24","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1002\/art.1780290314","volume":"29","author":"R Holmdahl","year":"1986","unstructured":"Holmdahl R, Rubin K, Klareskog L, Larsson E, Wigzell H: Characterization of the antibody response in mice with type II collagen-induced arthritis, using monoclonal anti-type II collagen antibodies. Arthritis Rheum. 1986, 29: 400-410.","journal-title":"Arthritis Rheum"},{"key":"1201_CR25","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1002\/(SICI)1097-0282(1998)47:2<127::AID-BIP2>3.0.CO;2-W","volume":"47","author":"M Goodman","year":"1998","unstructured":"Goodman M, Bhumralkar , Jefferson EA, Kwak J, Locardi E: Collagen mimetics. Biopolymers. 1998, 47: 127-142. 10.1002\/(SICI)1097-0282(1998)47:2<127::AID-BIP2>3.0.CO;2-W.","journal-title":"Biopolymers"},{"key":"1201_CR26","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1093\/rheumatology\/29.4.254","volume":"29","author":"C Buckee","year":"1990","unstructured":"Buckee C, Morgan K, Ayad S, Collins I, Clague RB, Holt PJ: Diversity of antibodies to type II collagen in patients with rheumatoid arthritis: detection by binding to alpha-chains and to cyanogen bromide peptides. Br J Rheumatol. 1990, 29: 254-258.","journal-title":"Br J Rheumatol"},{"key":"1201_CR27","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1007\/BF00300979","volume":"12","author":"MJ Rowley","year":"1992","unstructured":"Rowley MJ, Mackay IR, Brand CA, Bateman JF, Chan D: Epitope specificity of antibodies to type II collagen in rheumatoid arthritis and systemic lupus erythematosus. Rheumatol Int. 1992, 12: 65-69. 10.1007\/BF00300979.","journal-title":"Rheumatol Int"},{"key":"1201_CR28","doi-asserted-by":"publisher","first-page":"201","DOI":"10.3109\/08916939109001890","volume":"10","author":"J Worthington","year":"1991","unstructured":"Worthington J, Brass A, Morgan K: Identification of antibody epitopes within the CB-11 peptide of type II collagen. I. Detection of antibody binding sites by epitope scanning. Autoimmunity. 1991, 10: 201-207.","journal-title":"Autoimmunity"},{"key":"1201_CR29","doi-asserted-by":"publisher","first-page":"2339","DOI":"10.1002\/art.10472","volume":"46","author":"H Burkhardt","year":"2002","unstructured":"Burkhardt H, Koller T, Engstrom A, Nandakumar KS, Turnay J, Kraetsch HG, Kalden JR, Holmdahl R: Epitope-specific recognition of type II collagen by rheumatoid arthritis antibodies is shared with recognition by antibodies that are arthritogenic in collagen-induced arthritis in the mouse. Arthritis Rheum. 2002, 46: 2339-2348. 10.1002\/art.10472.","journal-title":"Arthritis Rheum"},{"key":"1201_CR30","doi-asserted-by":"publisher","first-page":"1120","DOI":"10.1002\/art.1780260910","volume":"26","author":"SS Kerwar","year":"1983","unstructured":"Kerwar SS, Englert ME, McReynolds RA, Landes MJ, Lloyd JM, Oronsky AL, Wilson FJ: Type II collagen-induced arthritis. Studies with purified anticollagen immunoglobulin. Arthritis Rheum. 1983, 26: 1120-1131.","journal-title":"Arthritis Rheum"},{"key":"1201_CR31","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1007\/BF01965042","volume":"25","author":"N Loutis","year":"1988","unstructured":"Loutis N, Bruckner P, Pataki A: Induction of erosive arthritis in mice after passive transfer of anti-type II collagen antibodies. Agents Actions. 1988, 25: 352-359.","journal-title":"Agents Actions"},{"key":"1201_CR32","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1111\/j.1365-3083.1990.tb02754.x","volume":"31","author":"R Holmdahl","year":"1990","unstructured":"Holmdahl R, Jansson L, Larsson A, Jonsson R: Arthritis in DBA\/1 mice induced with passively transferred type II collagen immune serum. Immunohistopathology and serum levels of anti-type II collagen auto-antibodies. Scand J Immunol. 1990, 31: 147-157.","journal-title":"Scand J Immunol"},{"key":"1201_CR33","doi-asserted-by":"publisher","first-page":"1023","DOI":"10.1002\/art.1780370707","volume":"37","author":"J Ronnelid","year":"1994","unstructured":"Ronnelid J, Lysholm J, Engstrom-Laurent A, Klareskog L, Heyman B: Local anti-type II collagen antibody production in rheumatoid arthritis synovial fluid. Evidence for an HLA-DR4-restricted IgG response. Arthritis Rheum. 1994, 37: 1023-1029.","journal-title":"Arthritis Rheum"},{"key":"1201_CR34","first-page":"770","volume":"15","author":"I Collins","year":"1988","unstructured":"Collins I, Morgan K, Clague RB, Brenchley PE, Holt PJ: IgG subclass distribution of antinative type II collagen and antidenatured type II collagen antibodies in patients with rheumatoid arthritis. J Rheumatol. 1988, 15: 770-774.","journal-title":"J Rheumatol"},{"key":"1201_CR35","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1002\/art.1780290114","volume":"29","author":"R Holmdahl","year":"1986","unstructured":"Holmdahl R, Jansson L, Larsson E, Rubin K, Klareskog L: Homologous type II collagen induces chronic and progressive arthritis in mice. Arthritis Rheum. 1986, 29: 106-113.","journal-title":"Arthritis Rheum"},{"key":"1201_CR36","doi-asserted-by":"publisher","first-page":"1531","DOI":"10.1172\/JCI115164","volume":"87","author":"HE Jasin","year":"1991","unstructured":"Jasin HE, Taurog JD: Mechanisms of disruption of the articular cartilage surface in inflammation. Neutrophil elastase increases availability of collagen type II epitopes for binding with antibody on the surface of articular cartilage. J Clin Invest. 1991, 87: 1531-1536.","journal-title":"J Clin Invest"},{"key":"1201_CR37","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1007\/s00281-003-0131-5","volume":"25","author":"D Kyburz","year":"2003","unstructured":"Kyburz D, Corr M: The KRN mouse model of inflammatory arthritis. Springer Semin Immunopathol. 2003, 25: 79-90. 10.1007\/s00281-003-0131-5.","journal-title":"Springer Semin Immunopathol"}],"container-title":["Arthritis Res Ther"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/ar1213.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/ar1213\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/ar1213.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T16:04:12Z","timestamp":1714061052000},"score":1,"resource":{"primary":{"URL":"https:\/\/arthritis-research.biomedcentral.com\/articles\/10.1186\/ar1213"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,8,11]]},"references-count":37,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2004,9]]}},"alternative-id":["1201"],"URL":"https:\/\/doi.org\/10.1186\/ar1213","relation":{},"ISSN":["1478-6354"],"issn-type":[{"value":"1478-6354","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,8,11]]},"assertion":[{"value":"2 April 2004","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 June 2004","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 June 2004","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 August 2004","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}],"article-number":"R477"}}