{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T13:56:06Z","timestamp":1791813366636,"version":"4.3.4"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2005,12,1]],"date-time":"2005-12-01T00:00:00Z","timestamp":1133395200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0\/"},{"start":{"date-parts":[[2005,12,1]],"date-time":"2005-12-01T00:00:00Z","timestamp":1133395200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arthritis Res Ther"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To study the inter-reader reliability of detecting abnormalities of sacroiliac (SI) joints in patients with recent-onset inflammatory back pain by magnetic resonance imaging (MRI), and to study the prevalence of inflammation and structural changes at various sites of the SI joints.<\/jats:p><jats:p>Sixty-eight patients with inflammatory back pain (at least four of the five following criteria: symptom onset before age 40, insidious onset, morning stiffness, duration &gt;3 months, improvement with exercise \u2014 or three out of five of these plus night pain) were included (38% male; mean age, 34.9 years [standard deviation 10.3]; 46% HLA-B27-positive; mean symptom duration, 18 months), with symptom duration &lt;2 years. A MRI scan of the SI joints was made in the coronal plane with the following sequences: T1-weighted spin echo, short-tau inversion recovery, T2-weighted fast-spin echo with fat saturation, and T1-spin echo with fat saturation after the administration of gadolinium. Both SI joints were scored for inflammation (separately for subchondral bone and bone marrow, joint space, joint capsule, ligaments) as well as for structural changes (erosions, sclerosis, ankylosis), by two observers independently. Agreement between the two readers was analysed by concordance and discordance rates and by kappa statistics.<\/jats:p><jats:p>Inflammation was present in 32 SI joints of 22 patients, most frequently located in bone marrow and\/or subchondral bone (29 joints in 21 patients). Readers agreed on the presence of inflammation in 85% of the cases in the right SI joint and in 78% of the cases in the left SI joint. Structural changes on MRI were present in 11 patients. Ten of these 11 patients also showed signs of inflammation.<\/jats:p><jats:p>Agreement on the presence or absence of inflammation and structural changes of SI joints by MRI was acceptable, and was sufficiently high to be useful in ascertaining inflammatory and structural changes due to sacroiliitis. About one-third of patients with recent-onset inflammatory back pain show inflammation, and about one-sixth show structural changes in at least one SI joint.<\/jats:p>","DOI":"10.1186\/ar1859","type":"journal-article","created":{"date-parts":[[2005,12,1]],"date-time":"2005-12-01T19:14:30Z","timestamp":1133464470000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":50,"title":["Magnetic resonance imaging changes of sacroiliac joints in patients with recent-onset inflammatory back pain: inter-reader reliability and prevalence of abnormalities"],"prefix":"10.1186","volume":"8","author":[{"given":"Liesbeth","family":"Heuft-Dorenbosch","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ren\u00e9","family":"Weijers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Landew\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sjef","family":"van der Linden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D\u00e9sir\u00e9e","family":"van der Heijde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2005,12,1]]},"reference":[{"key":"1737_CR1","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1002\/art.1780270301","volume":"27","author":"SM van der Linden","year":"1984","unstructured":"van der Linden SM, Valkenburg HA, de Jongh BM, Cats A: The risk of developing ankylosing spondylitis in HLA-B27 positive individuals. A comparison of relatives of spondylitis patients with the general population. Arthritis Rheum. 1984, 27: 241-249.","journal-title":"Arthritis Rheum"},{"key":"1737_CR2","doi-asserted-by":"publisher","first-page":"1218","DOI":"10.1002\/art.1780341003","volume":"34","author":"M Dougados","year":"1991","unstructured":"Dougados M, van der Linden S, Juhlin R, Huitfeldt B, Amor B, Calin A, Cats A, Dijkmans B, Olivieri I, Pasero G, The European Spondylarthropathy Study Group, et al: The European Spondylarthropathy Study Group preliminary criteria for the classification of spondylarthropathy. Arthritis Rheum. 1991, 34: 1218-1227.","journal-title":"Arthritis Rheum"},{"key":"1737_CR3","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1097\/00002281-200007000-00002","volume":"12","author":"E Feldtkeller","year":"2000","unstructured":"Feldtkeller E, Bruckel J, Khan MA: Scientific contributions of ankylosing spondylitis patient advocacy groups. Curr Opin Rheumatol. 2000, 12: 239-247. 10.1097\/00002281-200007000-00002.","journal-title":"Curr Opin Rheumatol"},{"key":"1737_CR4","first-page":"997","volume":"26","author":"A Spoorenberg","year":"1999","unstructured":"Spoorenberg A, de Vlam K, van der Heijde D, de Klerk E, Dougados M, Mielants H, van der Tempel , Boers M, van der Linden Sj: Radiological scoring methods in ankylosing spondylitis: reliability and sensitivity to change over one year. J Rheumatol. 1999, 26: 997-1002.","journal-title":"J Rheumatol"},{"key":"1737_CR5","doi-asserted-by":"publisher","first-page":"1039","DOI":"10.1002\/art.1780370709","volume":"37","author":"J Braun","year":"1994","unstructured":"Braun J, Bollow M, Eggens U, Konig H, Distler A, Sieper J: Use of dynamic magnetic resonance imaging with fast imaging in the detection of early and advanced sacroiliitis in spondylarthropathy patients. Arthritis Rheum. 1994, 37: 1039-1045.","journal-title":"Arthritis Rheum"},{"key":"1737_CR6","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1007\/s003930050154","volume":"58","author":"M Bollow","year":"1999","unstructured":"Bollow M, Loreck D, Banzer D, Brandt H, Zerbes K, Kourik W, Mellorowicz H, Backhaus M, Schmidt W, Bohl-Buhler M, et al: Diagnostic imaging of inflammation in the axial skeleton. Zeitschr Rheumatol. 1999, 58: 61-70. 10.1007\/s003930050154.","journal-title":"Zeitschr Rheumatol"},{"key":"1737_CR7","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1016\/S1521-6942(02)90250-0","volume":"16","author":"J Braun","year":"2002","unstructured":"Braun J, van der Heijde D: Imaging and scoring in ankylosing spondylitis. Best Pract Res Clin Rheumatol. 2002, 16: 573-604.","journal-title":"Best Pract Res Clin Rheumatol"},{"key":"1737_CR8","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1136\/ard.2003.011247","volume":"63","author":"M Rudwaleit","year":"2004","unstructured":"Rudwaleit M, van der Heijde D, Khan MA, Braun J, Sieper J: How to diagnose axial spondyloarthritis early. Ann Rheum Dis. 2004, 63: 535-543. 10.1136\/ard.2003.011247.","journal-title":"Ann Rheum Dis"},{"key":"1737_CR9","doi-asserted-by":"publisher","first-page":"2613","DOI":"10.1001\/jama.1977.03270510035017","volume":"237","author":"A Calin","year":"1977","unstructured":"Calin A, Porta J, Fries JF, Schurman DJ: Clinical history as a screening test for ankylosing spondylitis. JAMA. 1977, 237: 2613-2614. 10.1001\/jama.237.24.2613.","journal-title":"JAMA"},{"key":"1737_CR10","first-page":"1649","volume":"80","author":"J Bigot","year":"1999","unstructured":"Bigot J, Loeuille D, Chary-Valckenaere I, Pourel J, Cao MM, Blum A: Determination of the best diagnostic criteria of sacroiliitis with MRI. J Radiol. 1999, 80: 1649-1657.","journal-title":"J Radiol"},{"key":"1737_CR11","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1034\/j.1600-0455.2003.00034.x","volume":"44","author":"KB Puhakka","year":"2003","unstructured":"Puhakka KB, Jurik AG, Egund N, Schiottz-Christensen B, Stengaard-Pedersen K, van Overeem Hansen G, Christiansen J: Imaging of sacroiliitis in early seronegative spondylarthropathy. Assessment of abnormalities by MR in comparison with radiography and CT. Acta Radiol. 2003, 44: 218-229. 10.1034\/j.1600-0455.2003.00034.x.","journal-title":"Acta Radiol"},{"key":"1737_CR12","first-page":"393","volume":"19","author":"P Docherty","year":"1992","unstructured":"Docherty P, Mitchell MJ, MacMillan L, Mosher D, Barnes DC, Hanly JG: Magnetic resonance imaging in the detection of sacroiliitis. J Rheumatol. 1992, 19: 393-401.","journal-title":"J Rheumatol"},{"key":"1737_CR13","first-page":"2050","volume":"32","author":"R Landew\u00e9","year":"2005","unstructured":"Landew\u00e9 R, Hermann K-G, van der Heijde D, Baraliakos X, Jurik A-G, Lambert R, Ostergaard M, Rudwaleit M, Salonen D, Braun J, the ASAS\/OMERACT MRI in AS Working Group: Scoring sacro-iliac joints by magnetic resonance imaging. A multiple-reader reliability experiment. J Rheumatol. 2005, 32: 2050-2055.","journal-title":"J Rheumatol"}],"container-title":["Arthritis Research &amp; Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/ar1859.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/ar1859\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/ar1859.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T10:26:24Z","timestamp":1728383184000},"score":1,"resource":{"primary":{"URL":"https:\/\/arthritis-research.biomedcentral.com\/articles\/10.1186\/ar1859"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,12,1]]},"references-count":13,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2005,2]]}},"alternative-id":["1737"],"URL":"https:\/\/doi.org\/10.1186\/ar1859","relation":{},"ISSN":["1478-6354"],"issn-type":[{"value":"1478-6354","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,12,1]]},"assertion":[{"value":"6 July 2005","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 October 2005","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 November 2005","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 December 2005","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"R11"}}