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This study assessed the effects of a pre-visit website with tailored information and question prompt sheet (QPS), named E-info gene\n                      <jats:sup>ca<\/jats:sup>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A total of 197 counselees were randomized to receive usual care (UC) or UC plus E-info gene\n                      <jats:sup>ca<\/jats:sup>\n                      . All counselees completed a pre- and post-visit questionnaire and visits were videotaped. We studied effects on counselees' information recall, knowledge about breast cancer and heredity, fulfillment of needs, risk perception alignment, anxiety and perceived personal control, using multilevel regression analyses.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Intent-to-treat analysis showed that counselees in the intervention group (\n                      <jats:italic>n<\/jats:italic>\n                      = 103) had higher levels of recall of information from the consultation (\u03b2 = .32; confidence interval (CI): .04 to .60;\n                      <jats:italic>P<\/jats:italic>\n                      = .02; d = .17) and post-visit knowledge of breast cancer and heredity (\u03b2 = .30; CI: .03 to .57;\n                      <jats:italic>P<\/jats:italic>\n                      = .03) than counselees in the UC group (\n                      <jats:italic>n<\/jats:italic>\n                      = 94). Also, intervention group counselees reported better fulfilment of information needs (\u03b2 = .31; CI: .03 to .60;\n                      <jats:italic>P<\/jats:italic>\n                      = .03). The effects of the intervention were strongest for those counselees who did not receive an indication for DNA testing. Their recall scores showed a larger increase (\u03b2 = .95; CI: .32 to 1.59;\n                      <jats:italic>P<\/jats:italic>\n                      = .003; d = .30) and their anxiety levels dropped more in the intervention compared to the UC group (\u03b2 = -.60; CI: -1.12 to -.09;\n                      <jats:italic>P<\/jats:italic>\n                      = .02). No intervention effects were found after the first visit on risk perception alignment or perceived personal control.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study shows that pre-counseling education, using tailored information technology, leads to more effective first visits for breast cancer genetic counseling, in particular for counselees who received no indication for DNA testing and, therefore, had no indication for a second visit. Future study should focus on the effects of a pre-visit website on the outcomes after a complete series of visits.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration<\/jats:title>\n                    <jats:p>\n                      Dutch Trial Register\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.controlled-trials.com\/ISRCTN82643064\">ISRCTN82643064<\/jats:ext-link>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/bcr3133","type":"journal-article","created":{"date-parts":[[2012,3,6]],"date-time":"2012-03-06T08:14:12Z","timestamp":1331021652000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Effects of a pre-visit educational website on information recall and needs fulfilment in breast cancer genetic counselling, a randomized controlled trial"],"prefix":"10.1186","volume":"14","author":[{"given":"Akke","family":"Albada","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"van Dulmen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jozien M","family":"Bensing","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margreet GEM","family":"Ausems","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,3,6]]},"reference":[{"key":"2933_CR1","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1034\/j.1399-0004.2001.600501.x","volume":"60","author":"BB Biesecker","year":"2001","unstructured":"Biesecker BB: Goals of genetic counseling. 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