{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T04:12:58Z","timestamp":1750479178742},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1999,6,1]],"date-time":"1999-06-01T00:00:00Z","timestamp":928195200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[1999,6,1]],"date-time":"1999-06-01T00:00:00Z","timestamp":928195200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Acta Vet Scand"],"published-print":{"date-parts":[[1999,6]]},"DOI":"10.1186\/bf03547029","type":"journal-article","created":{"date-parts":[[2020,11,28]],"date-time":"2020-11-28T19:02:47Z","timestamp":1606590167000},"page":"121-132","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Establishment of Ascaris suum in the Pig: Development of Immunity Following a Single Primary Infection"],"prefix":"10.1186","volume":"40","author":[{"given":"A. B.","family":"Helwigh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Nansen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[1999,6,1]]},"reference":[{"key":"BF03547029_CR1","first-page":"47","volume":"36","author":"JA Ajayi","year":"1988","unstructured":"Ajayi JA, Arabs WL, Adeleye GA: Helminths and protozoa of pigs on the Jos plateau, Nigeria: occurrence, age, incidence and seasonal distribution. Bull. Anim. Health. Prod. Afr. 1988, 36, 47\u201354.","journal-title":"Bull. Anim. Health. Prod. Afr"},{"key":"BF03547029_CR2","first-page":"322","volume":"28","author":"S Andersen","year":"1976","unstructured":"Andersen S: The influence of Ascaris suum upon growth rates in pigs. Nord. Vet. Med. 1976, 28, 322\u2013330.","journal-title":"Nord. Vet. Med"},{"key":"BF03547029_CR3","unstructured":"Astrup P, Br\u00f8chner-Mortensen K, Faber M: Klinisk laboratorieteknik (Clinical laboratory technique). Copenhagen, August Bangs Forlag, 1959."},{"key":"BF03547029_CR4","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1017\/S0031182098003382","volume":"117","author":"J Boes","year":"1998","unstructured":"Boes J, Medley GF, Eriksen L, Roepstorff A, Nansen P: Distribution of Ascaris suum in experimentally and naturally infected pigs and comparison with Ascaris lumbricoides infections in humans. Parasitology 1998, 117, 589\u2013597.","journal-title":"Parasitology"},{"key":"BF03547029_CR5","unstructured":"Eriksen L: Host parasite relations in Ascaris suum infection in pigs and mice. Institute of Internal Medicine, Royal Veterinary and Agricultural University. Doctoral thesis. 1981, pp 1\u2013193."},{"key":"BF03547029_CR6","first-page":"233","volume":"32","author":"L Eriksen","year":"1980","unstructured":"Eriksen L, Andersen S, Nielsen K, Pedersen A, Nielsen J: Experimental Ascaris suum infection in the pig. Serological response, eosinophilia in peripheral blood, occurrence of white spots in the liver and worm recovery from the intestine. Nord. Vet. Med. 1980, 32, 233\u2013242.","journal-title":"Serological response, eosinophilia in peripheral blood, occurrence of white spots in the liver and worm recovery from the intestine. Nord. Vet. Med"},{"key":"BF03547029_CR7","doi-asserted-by":"crossref","unstructured":"Eriksen L, Lind P, Nansen P, RoepstorffA, Urban JF: Resistance to Ascaris suum in parasite na\u00efve and naturally exposed growers, finishers and sows. Vet. Parasitol. 1992a, 41, 137\u2013149.","DOI":"10.1016\/0304-4017(92)90017-4"},{"key":"BF03547029_CR8","doi-asserted-by":"crossref","unstructured":"Eriksen L, Nansen P, RoepstorffA, Lind P, Nilsson O: Response to repeated inoculations with Ascaris suum eggs in pigs during the fattening period. I. Studies on worm population kinetics. Parasitol. Res. 1992b, 78, 241\u2013246.","DOI":"10.1007\/BF00931733"},{"key":"BF03547029_CR9","unstructured":"Jungersen G: Experimental Ascaris suum infection: manipulated infections and immune responses to larval migration in pigs. Royal Veterinary and Agricultural University, Copenhagen, Denmark. Ph.D thesis. 1998,"},{"key":"BF03547029_CR10","first-page":"151","volume":"1","author":"RJ J\u00f8rgensen","year":"1975","unstructured":"J\u00f8rgensen RJ, Nansen P, Nielsen K, Eriksen L, Andersen S: Experimental Ascaris suum infection in the pig. Population kinetic following low and high levels of primary infection in piglets. Vet. Parasitol. 1975, 1, 151\u2013157.","journal-title":"Population kinetic following low and high levels of primary infection in piglets. Vet. Parasitol"},{"key":"BF03547029_CR11","doi-asserted-by":"publisher","first-page":"499","DOI":"10.2307\/3275608","volume":"50","author":"GW Kelley","year":"1964","unstructured":"Kelley GW, Nayak DP: Acquired immunity to migrating larvae of Ascaris suum induced in pigs by repeated oral inoculations on infective eggs. J. Parasitol. 1964, 50, 499\u2013503.","journal-title":"J. Parasitol"},{"key":"BF03547029_CR12","first-page":"240","volume":"79","author":"P Lind","year":"1993","unstructured":"Lind P, Eriksen L, Nansen P, Nilsson O, Roepstorff A: Response to repeated inoculations with Ascaris suum eggs in pigs during the fattening period. II. Specific IgA, IgG, and IgM antibodies determined by enzyme-linked immunosorbent assay. Parasitol. Res. 1993, 79, 240\u2013244.","journal-title":"II. Specific IgA, IgG, and IgM antibodies determined by enzyme-linked immunosorbent assay. Parasitol. Res"},{"key":"BF03547029_CR13","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1016\/S0749-0720(15)31255-X","volume":"2","author":"KD Murrell","year":"1986","unstructured":"Murrell KD: Epidemiology, pathogenesis, and control of major swine helminth parasites. Vet. Clin. North. Am. Food. Anim. Pract. 1986, 2, 439\u2013454.","journal-title":"Vet. Clin. North. Am. Food. Anim. Pract"},{"key":"BF03547029_CR14","first-page":"393","volume":"31","author":"A Oksanen","year":"1990","unstructured":"Oksanen A, Eriksen L, RoepstorffA, Nansen P, Lind P: Embryonation and infectivity of Ascaris suum eggs. A Comparison of eggs collected from worm uteri with eggs isolated from pig faeces. Acta Vet. Scand. 1990, 31, 393\u2013398.","journal-title":"A Comparison of eggs collected from worm uteri with eggs isolated from pig faeces. Acta Vet. Scand"},{"key":"BF03547029_CR15","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1017\/S0031182000081956","volume":"111","author":"S Petkevicius","year":"1995","unstructured":"Petkevicius S, Bj\u00f8rn H, Roepstorff A, Nansen P, Bach Knudsen KE, Barnes EH, Jensen K: The effect of two types of diet on populations of A. suum and O. dentatum in experimentally infected pigs. Parasitology 1995, 111, 395\u2013402.","journal-title":"Parasitology"},{"key":"BF03547029_CR16","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1017\/S0031182097001480","volume":"115","author":"A Roepstorff","year":"1997","unstructured":"Roepstorff A, Eriksen L, Slotved H-C, Nansen P: Experimental Ascaris suum infections in the pig: worm population kinetics following single inoculations with three doses of infective eggs. Parasitology 1997, 115, 443\u2013452.","journal-title":"Parasitology"},{"key":"BF03547029_CR17","doi-asserted-by":"crossref","unstructured":"Roepstorff A, Jorsal SE: Prevalence of helminth infections in swine in Denmark. Vet. Parasitol. 1989,33, 231\u2013239.","DOI":"10.1016\/0304-4017(89)90133-7"},{"key":"BF03547029_CR18","doi-asserted-by":"crossref","unstructured":"Roepstorff A, Murrell KD: Transmission Dynamics of helminth parasites of pigs on continuous pasture: Ascaris suum and Trichuris suis. Int. J. Parasitol. 1997,27, 563\u2013572.","DOI":"10.1016\/S0020-7519(97)00022-2"},{"key":"BF03547029_CR19","unstructured":"Roepstorff A, Nansen P: The epidemiology, diagnosis and control of helminth parasites of swine. A FAO handbook (1999)."},{"key":"BF03547029_CR20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/BF03547094","volume":"7","author":"O Ron\u00e9us","year":"1966","unstructured":"Ron\u00e9us O: Studies in the aetiology and pathogenesis of white spots in the liver of pigs. Acta Vet. Scand. 1966, 7, 1\u2013112.","journal-title":"Acta Vet. Scand"},{"key":"BF03547029_CR21","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1186\/BF03548483","volume":"38","author":"H-C Slotved","year":"1997","unstructured":"Slotved H-C, Barnes EH, Eriksen L, Roepstorff A, Nansen P, Bj\u00f8rn H: Use of an agar-gel technique for large scale application to recovering Ascaris suum from the intestinal contents of pigs. Acta Vet. Scand. 1997, 38, 207\u2013212.","journal-title":"Acta Vet. Scand"},{"key":"BF03547029_CR22","doi-asserted-by":"publisher","first-page":"612","DOI":"10.2307\/3283786","volume":"82","author":"H-C Slotved","year":"1995","unstructured":"Slotved H-C, Roepstorff A, Barnes EH, Eriksen L, Nansen P: Comparison of two methods for recovery of migrating Ascaris suum larvae from the liver and lungs of pigs. J. Parasitol. 1995, 82, 612\u2013615.","journal-title":"J. Parasitol"},{"key":"BF03547029_CR23","unstructured":"Stewart TB: Losing millions to the insidious invaders. Pigs-Misset 1996, June, 8\u20139."},{"key":"BF03547029_CR24","first-page":"151","volume":"38","author":"LF Taffs","year":"1964","unstructured":"Taffs LF: Immunological studies on experimental infection of pigs with Ascaris suum Goeze, 1782. III. The antibody response and acquired immunity. J. Helminthol. 1964, 38, 151\u2013158.","journal-title":"III. The antibody response and acquired immunity. J. Helminthol"},{"key":"BF03547029_CR25","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1016\/S0749-0720(15)31218-4","volume":"2","author":"JF Urban","year":"1986","unstructured":"Urban JF: The epidemiology and control of swine parasites. Immunity and vaccines. Vet. Clin. North. Am. Food. Anim. Pract. 1986, 2, 765\u2013778.","journal-title":"Immunity and vaccines. Vet. Clin. North. Am. Food. Anim. Pract"},{"key":"BF03547029_CR26","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/0014-4894(88)90051-3","volume":"66","author":"JF Urban","year":"1988","unstructured":"Urban JF, Alizadeh H, Romanowski D: Ascaris suum: Development of intestinal immunity to infective second-stage larvae in swine. Exp. Parasitol. 1988, 66, 66\u201377.","journal-title":"Exp. Parasitol"},{"key":"BF03547029_CR27","doi-asserted-by":"crossref","unstructured":"Urban JF, Romanowski D: Ascaris suum: Protective immunity in pigs immunized with products from eggs and larvae. Exp. Parasitol. 1985, 60, 245\u2013 254.","DOI":"10.1016\/0014-4894(85)90028-1"},{"key":"BF03547029_CR28","first-page":"2104","volume":"45","author":"JF Urban","year":"1984","unstructured":"Urban JF, Tromba FG: An ultraviolet-attenuated egg vaccine for swine ascariasis: parameters affecting the development of protective immunity. Am. J. Vet. Res. 1984, 45, 2104\u20132108.","journal-title":"Am. J. Vet. Res"},{"key":"BF03547029_CR29","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/0304-4017(90)90023-5","volume":"37","author":"S Yang","year":"1990","unstructured":"Yang S, Gaafar SM, Bottoms GD: Effects of multiple dose infections with Ascaris suum on blood gastrointestinal hormone levels in pigs. Vet. Parasitol. 1990, 37, 31\u201344.","journal-title":"Vet. Parasitol"},{"key":"BF03547029_CR30","first-page":"127","volume":"23","author":"S Yoshihara","year":"1983","unstructured":"Yoshihara S, Nakagawa M, Suda H, Ikeda K, Hanashiro K: White spots of the liver in pigs experimentally infected with Ascaris suum. National Institute of Animal Health Q. (Japan) 1983, 23, 127\u2013137.","journal-title":"(Japan)"},{"key":"BF03547029_CR31","first-page":"64","volume":"35","author":"S Yoshihara","year":"1987","unstructured":"Yoshihara S, Nakagawa M, Suda H, Kobayashi K: Enhancement of white spots lesions in the liver of pigs repeatedly infected with Ascaris suum. J. Tokyo Vet. Animal Sci. 1987, 35, 64\u201371.","journal-title":"Tokyo Vet. Animal Sci"}],"container-title":["Acta Veterinaria Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/BF03547029.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/BF03547029\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/BF03547029.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,13]],"date-time":"2021-05-13T08:17:04Z","timestamp":1620893824000},"score":1,"resource":{"primary":{"URL":"https:\/\/actavetscand.biomedcentral.com\/articles\/10.1186\/BF03547029"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,6]]},"references-count":31,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1999,6]]}},"alternative-id":["BF03547029"],"URL":"https:\/\/doi.org\/10.1186\/bf03547029","relation":{},"ISSN":["1751-0147"],"issn-type":[{"value":"1751-0147","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,6]]},"assertion":[{"value":"10 October 1998","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 January 1999","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 June 1999","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}