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The role of the Danish Headache Society is to educate and advocate for the needs of patients with headache and facial pain. Therefore, the Danish Headache Society has launched a third version of the guideline for the diagnosis, organization and treatment of the most common types of headaches and facial pain in Denmark. The second edition was published in Danish in 2010 and has been a great success, but as new knowledge and treatments have emerged it was timely to revise the guideline. The recommendations for the primary headaches and facial pain are largely in accordance with the European guidelines produced by the European Academy of Neurology. The guideline should be used a practical tool for use in daily clinical practice for primary care physicians, neurologists with a common interest in headache, as well as other health-care professionals treating headache patients. The guideline first describes how to examine and diagnose the headache patient and how headache treatment is organized in Denmark. This description is followed by sections on the characteristics, diagnosis and treatment of each of the most common primary and secondary headache disorders and trigeminal neuralgia. The guideline includes many tables to facilitate a quick overview. Finally, the particular challenges regarding migraine and female hormones as well as headache in children are addressed.<\/jats:p>","DOI":"10.1186\/s10194-021-01228-4","type":"journal-article","created":{"date-parts":[[2021,4,8]],"date-time":"2021-04-08T13:03:17Z","timestamp":1617886997000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":64,"title":["Reference programme: diagnosis and treatment of headache disorders and facial pain. 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Faisal M. Amin has received lecturing fee or participated in advisory boards for TEVA, Eli Lilly, Lundbeck and Novartis. Faisal M. Amin is principal investigator for phase 4 trials for TEVA and Novartis. Faisal M. Amin is the current president of the Danish Headache Society, and serve as associate editor for Headache Medicine and Frontiers in Pain Research. Rigmor H. Jensen is or has been principal investigator in studies sponsored by Lundbeck, Eli Lilly and ATI and has given lectures for Novartis, Lundbeck, Allergan, TEVA and ATI. Messoud Ashina is a consultant, speaker, or scientific advisor for AbbVie, Allergan, Amgen, Eli Lilly, Lundbeck, Novartis, and Teva; primary investigator for AbbVie, Amgen, Eli Lilly, Lundbeck, Novartis, and Teva trials. Messoud Ashina serves as associate editor of Cephalalgia; associate editor of Headache; associate editor of the Journal of Headache and Pain. Messoud Ashina is President of the International Headache Society. Nunu Lund has given lectures for laegekurser.dk and ABG Investment. Lars Bendtsen has served on the scientific advisory board for Novartis, Allergan, Teva, Lundbeck and Eli Lilly. Henrik W. Schytz has served on scientific advisory board for Lundbeck and Eli Lilly and has received lecturing fee from TEVA and Novartis. Henrik W. Schytz has received research grants from Novartis. Lars Poulsen, Dagmar Beier, Karen Aegidius, Lise L. Thomsen, Flemming W.\u00a0Bach, Hanne Johansen, Jakob M. Hansen, Helge Kasch, Signe B. Munksgaard, Lars Poulsen, Peter T. Schmidt-Hansen and Vlasta V. Cvetkovic reports no conflicts of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"22"}}