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Yet, few studies focused on combined lifestyles, particularly in Chinese populations. This cross-sectional study aimed to investigate the relationships of a combined lifestyle index with migraine in Hong Kong Chinese women.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Baseline data from a cohort study named Migraine Exposures and Cardiovascular Health in Hong Kong Chinese Women (MECH-HK) were used for analysis. In total 3510 women aged 55.2\u2009\u00b1\u20099.1\u2009years were included. The combined lifestyle index comprised eight lifestyle factors: smoking, physical activity, sleep, stress, fatigue, diet, body mass index, and alcohol. Each component was attributed a point of 0 (unhealthy) or 1 (healthy). The overall index was the sum of these points, ranging from 0 (the least healthy) to 8 points (the healthiest). Migraine was diagnosed by the International Classification of Headache Disorders 3rd edition. Additionally, for women with migraine, the data on migraine attack frequency (attacks\/month) was collected.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>A total of 357 women with migraine (10.2%) were identified. The prevalence of migraine for the 0\u20133-point, 4-point, 5-point, 6-point, and 7\u20138-point groups were 18.0% (162\/899), 10.9% (86\/788), 6.6% (51\/776), 6.0% (38\/636), and 4.9% (20\/411), respectively. In the most-adjusted model, compared to the 0\u20133-point group, the odds ratios and 95% confidence intervals for the 4-point, 5-point, 6-point, and 7\u20138-point groups were 0.57 (0.43\u20130.75), 0.33 (0.24\u20130.46), 0.30 (0.21\u20130.44), and 0.25 (0.15\u20130.41), respectively (all <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). For each component, migraine was significantly associated with sleep, stress, fatigue, and diet; but was unrelated to smoking, physical activity, body mass index, and alcohol. Among women with migraine, per point increase in the combined lifestyle index was associated with a reduced migraine attack frequency (\u03b2\u2009=\u2009\u2212\u20090.55; 95% confidence interval\u2009=\u2009\u2212\u20090.82, \u2212\u20090.28; p\u2009&lt;\u20090.001).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>A combined lifestyle index was inversely associated with migraine and migraine attack frequency in Hong Kong Chinese women. Adhering to a healthy lifestyle pattern might be beneficial to the prevention of migraine attacks. Conversely, it is also plausible that women with migraine might have a less healthy lifestyle pattern compared to those without headaches.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s10194-024-01729-y","type":"journal-article","created":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T11:02:38Z","timestamp":1708426958000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Associations of combined lifestyle index with migraine prevalence and headache frequency: a cross-sectional study from the MECH-HK study"],"prefix":"10.1186","volume":"25","author":[{"given":"Yunyang","family":"Deng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harry Haoxiang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei Wan","family":"Ngai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dexing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangyan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao Jie","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,2,20]]},"reference":[{"issue":"1","key":"1729_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/j.1468-2982.2008.01709.x","volume":"38","author":"J Olesen","year":"2018","unstructured":"Olesen J (2018) Headache Classification Committee of the International Headache Society (I) The International Classification of Headache Disorders, 3rd edition. 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