{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T18:56:51Z","timestamp":1782845811000,"version":"3.54.5"},"reference-count":91,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T00:00:00Z","timestamp":1738800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T00:00:00Z","timestamp":1738800000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Headache Pain"],"DOI":"10.1186\/s10194-025-01958-9","type":"journal-article","created":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T07:57:20Z","timestamp":1738828640000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Headaches attributed to cranial and cervical artery dissections"],"prefix":"10.1186","volume":"26","author":[{"given":"Diana","family":"Doukhi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phanie","family":"Debette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9rome","family":"Mawet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,2,6]]},"reference":[{"key":"1958_CR1","unstructured":"Lucado J, Paez K, Elixhauser A (2011) Headaches in U.S. hospitals and emergency departments, 2008. Healthcare Cost and utilization project (HCUP) statistical briefs. Agency for Healthcare Research and Quality (US)"},{"issue":"1","key":"1958_CR2","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1186\/s10194-019-1053-5","volume":"5","author":"A Doretti","year":"2019","unstructured":"Doretti A, Shestaritc I, Ungaro D et al (2019) School of Advanced studies of the European Headache Federation (EHF-SAS). Headaches in the emergency department -a survey of patients\u2019 characteristics, facts and needs. J Headache Pain 5(1):100. https:\/\/doi.org\/10.1186\/s10194-019-1053-5","journal-title":"J Headache Pain"},{"key":"1958_CR3","doi-asserted-by":"publisher","first-page":"684","DOI":"10.1111\/j.1468-2982.2006.01093.x","volume":"26","author":"JN Goldstein","year":"2006","unstructured":"Goldstein JN, Camargo CA Jr, Pelletier AJ, Edlow JA (2006) Headache in United States emergency departments: demographics, work-up and frequency of pathological diagnoses. Cephalalgia: Int J Headache 26:684\u2013690. https:\/\/doi.org\/10.1111\/j.1468-2982.2006.01093.x","journal-title":"Cephalalgia: Int J Headache"},{"key":"1958_CR4","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1016\/j.nrleng.2020.06.018","volume":"38","author":"D Garc\u00eda-Azor\u00edn","year":"2023","unstructured":"Garc\u00eda-Azor\u00edn D, Abelaira-Freire J, Rodriguez-Adrada E et al (2023) Study about the Manchester Triage System subtriage in patients that visited the Emergency Department due to headache. Neurologia 38:270\u2013277. https:\/\/doi.org\/10.1016\/j.nrleng.2020.06.018","journal-title":"Neurologia"},{"key":"1958_CR5","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1177\/0333102421999045","volume":"41","author":"JF Rothrock","year":"2021","unstructured":"Rothrock JF, Diener HC (2021) Headache secondary to cerebrovascular disease. Cephalalgia: Int J Headache 41:479\u2013492. https:\/\/doi.org\/10.1177\/0333102421999045","journal-title":"Cephalalgia: Int J Headache"},{"key":"1958_CR6","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1177\/0333102420981721","volume":"41","author":"D Garc\u00eda-Azor\u00edn","year":"2021","unstructured":"Garc\u00eda-Azor\u00edn D, Gonz\u00e1lez-Garc\u00eda N, Abelaira-Freire J et al (2021) Management of thunderclap headache in the emergency room: a retrospective cohort study. Cephalalgia: Int J Headache 41:711\u2013720. https:\/\/doi.org\/10.1177\/0333102420981721","journal-title":"Cephalalgia: Int J Headache"},{"key":"1958_CR7","doi-asserted-by":"publisher","unstructured":"Headache Classification Committee of the International Headache Society (IHS) (2013) The International classification of Headache disorders, 3rd edition (beta version). Cephalalgia 33:629\u2013808. https:\/\/doi.org\/10.1177\/0333102413485658","DOI":"10.1177\/0333102413485658"},{"key":"1958_CR8","doi-asserted-by":"publisher","first-page":"954","DOI":"10.1016\/S1474-4422(18)30322-3","volume":"17","author":"LJ Stovner","year":"2018","unstructured":"Stovner LJ, Nichols E, Steiner TJ et al (2018) Global, regional, and national burden of migraine and tension-type headache, 1990\u20132016: a systematic analysis for the global burden of Disease Study 2016. Lancet Neurol 17:954\u2013976. https:\/\/doi.org\/10.1016\/S1474-4422(18)30322-3","journal-title":"Lancet Neurol"},{"key":"1958_CR9","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1177\/03331024211068073","volume":"42","author":"HM Al-Khazali","year":"2022","unstructured":"Al-Khazali HM, Younis S, Al-Sayegh Z et al (2022) Prevalence of neck pain in migraine: a systematic review and meta-analysis. Cephalalgia: Int J Headache 42:663\u2013673. https:\/\/doi.org\/10.1177\/03331024211068073","journal-title":"Cephalalgia: Int J Headache"},{"key":"1958_CR10","doi-asserted-by":"publisher","first-page":"1809","DOI":"10.1212\/01.wnl.0000244486.30455.71","volume":"67","author":"VH Lee","year":"2006","unstructured":"Lee VH, Brown RD Jr, Mandrekar JN, Mokri B (2006) Incidence and outcome of cervical artery dissection: a population-based study. Neurology 67:1809\u20131812. https:\/\/doi.org\/10.1212\/01.wnl.0000244486.30455.71","journal-title":"Neurology"},{"key":"1958_CR11","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1016\/S1474-4422(09)70084-5","volume":"8","author":"S Debette","year":"2009","unstructured":"Debette S, Leys D (2009) Cervical-artery dissections: predisposing factors, diagnosis, and outcome. Lancet Neurol 8:668\u2013678. https:\/\/doi.org\/10.1016\/S1474-4422(09)70084-5","journal-title":"Lancet Neurol"},{"key":"1958_CR12","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1111\/ijs.12154","volume":"9","author":"Y B\u00e9jot","year":"2014","unstructured":"B\u00e9jot Y, Daubail B, Debette S et al (2014) Incidence and outcome of cerebrovascular events related to cervical artery dissection: the Dijon Stroke Registry. Int J Stroke: Official J Int Stroke Soc 9:879\u2013882. https:\/\/doi.org\/10.1111\/ijs.12154","journal-title":"Int J Stroke: Official J Int Stroke Soc"},{"key":"1958_CR13","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1016\/S1474-4422(15)00009-5","volume":"14","author":"S Debette","year":"2015","unstructured":"Debette S, Compter A, Labeyrie MA et al (2015) Epidemiology, pathophysiology, diagnosis, and management of intracranial artery dissection. Lancet Neurol 14:640\u2013654. https:\/\/doi.org\/10.1016\/S1474-4422(15)00009-5","journal-title":"Lancet Neurol"},{"key":"1958_CR14","doi-asserted-by":"publisher","first-page":"1950","DOI":"10.1212\/WNL.0b013e318293e2eb","volume":"80","author":"ST Engelter","year":"2013","unstructured":"Engelter ST, Grond-Ginsbach C, Metso TM et al (2013) Cervical artery dissection: trauma and other potential mechanical trigger events. Neurology 80:1950\u20131957. https:\/\/doi.org\/10.1212\/WNL.0b013e318293e2eb","journal-title":"Neurology"},{"key":"1958_CR15","doi-asserted-by":"publisher","first-page":"1174","DOI":"10.1212\/WNL.0b013e31822f03fc","volume":"77","author":"S Debette","year":"2011","unstructured":"Debette S, Grond-Ginsbach C, Bodenant M et al (2011) Differential features of carotid and vertebral artery dissections: the CADISP Study. Neurology 77:1174\u20131181. https:\/\/doi.org\/10.1212\/WNL.0b013e31822f03fc","journal-title":"Neurology"},{"key":"1958_CR16","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1007\/BF00919596","volume":"242","author":"M Sturzenegger","year":"1995","unstructured":"Sturzenegger M (1995) Spontaneous internal carotid artery dissection: early diagnosis and management in 44 patients. J Neurol 242:231\u2013238. https:\/\/doi.org\/10.1007\/BF00919596","journal-title":"J Neurol"},{"key":"1958_CR17","doi-asserted-by":"publisher","first-page":"1021","DOI":"10.1136\/jnnp.2006.094359","volume":"77","author":"M Arnold","year":"2006","unstructured":"Arnold M, Cumurciuc R, Stapf C et al (2006) Pain as the only symptom of cervical artery dissection. J Neurol Neurosurg Psychiatry 77:1021\u20131024. https:\/\/doi.org\/10.1136\/jnnp.2006.094359","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"1958_CR18","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1007\/s00415-018-9111-5","volume":"266","author":"Y Wang","year":"2019","unstructured":"Wang Y, Cheng W, Lian Y et al (2019) Characteristics and relative factors of headache caused by cervicocerebral artery dissection. J Neurol 266:298\u2013305. https:\/\/doi.org\/10.1007\/s00415-018-9111-5","journal-title":"J Neurol"},{"key":"1958_CR19","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1111\/ijs.12546","volume":"100","author":"K Fukuhara","year":"2015","unstructured":"Fukuhara K, Ogata T, Ouma S et al (2015) Impact of initial symptom for accurate diagnosis of vertebral artery dissection. Int J Stroke: Official J Int Stroke Soc 10 Suppl A 100:30\u201333. https:\/\/doi.org\/10.1111\/ijs.12546","journal-title":"Int J Stroke: Official J Int Stroke Soc 10 Suppl A"},{"key":"1958_CR20","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1016\/j.jstrokecerebrovasdis.2018.10.034","volume":"28","author":"Y Wang","year":"2019","unstructured":"Wang Y, Cheng W, Lian Y (2019) The Headache and Neck Pain in ischemic stroke patients caused by Cervicocerebral Artery Dissection. A case-control study. J Stroke Cerebrovasc Diseases: Official J Natl Stroke Association 28:557\u2013561. https:\/\/doi.org\/10.1016\/j.jstrokecerebrovasdis.2018.10.034","journal-title":"J Stroke Cerebrovasc Diseases: Official J Natl Stroke Association"},{"key":"1958_CR21","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1016\/j.jns.2016.01.062","volume":"362","author":"H Kobayashi","year":"2016","unstructured":"Kobayashi H, Morishita T, Ogata T et al (2016) Extracranial and intracranial vertebral artery dissections: a comparison of clinical findings. J Neurol Sci 362:244\u2013250. https:\/\/doi.org\/10.1016\/j.jns.2016.01.062","journal-title":"J Neurol Sci"},{"key":"1958_CR22","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1111\/head.14454","volume":"63","author":"Y Hashimoto","year":"2023","unstructured":"Hashimoto Y, Matsushige T, Kawano R et al (2023) Headache characteristics to screen for cervicocerebral artery dissection in patients with acute onset unusual headache. Headache 63:283\u2013289. https:\/\/doi.org\/10.1111\/head.14454","journal-title":"Headache"},{"key":"1958_CR23","doi-asserted-by":"publisher","first-page":"21653","DOI":"10.1038\/s41598-023-48941-5","volume":"13","author":"SJ Lee","year":"2023","unstructured":"Lee SJ, Lee JS, Kim M et al (2023) Significance of headache in intracranial vertebrobasilar artery dissections: an observational study. Sci Rep 13:21653. https:\/\/doi.org\/10.1038\/s41598-023-48941-5","journal-title":"Sci Rep"},{"key":"1958_CR24","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1007\/s10072-018-3576-y","volume":"40","author":"S Gallerini","year":"2019","unstructured":"Gallerini S, Marsili L, Bartalucci M et al (2019) Headache secondary to cervical artery dissections: practice pointers. Neurol Sciences: Official J Italian Neurol Soc Italian Soc Clin Neurophysiol 40:613\u2013615. https:\/\/doi.org\/10.1007\/s10072-018-3576-y","journal-title":"Neurol Sciences: Official J Italian Neurol Soc Italian Soc Clin Neurophysiol"},{"key":"1958_CR25","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1161\/01.str.26.2.235","volume":"26","author":"V Biousse","year":"1995","unstructured":"Biousse V, D\u2019Anglejan-Chatillon J, Touboul PJ et al (1995) Time course of symptoms in extracranial carotid artery dissections. A series of 80 patients. Stroke 26:235\u2013239. https:\/\/doi.org\/10.1161\/01.str.26.2.235","journal-title":"Stroke"},{"key":"1958_CR26","doi-asserted-by":"publisher","first-page":"1517","DOI":"10.1212\/wnl.45.8.1517","volume":"45","author":"PL Silbert","year":"1995","unstructured":"Silbert PL, Mokri B, Schievink WI (1995) Headache and neck pain in spontaneous internal carotid and vertebral artery dissections. Neurology 45:1517\u20131522. https:\/\/doi.org\/10.1212\/wnl.45.8.1517","journal-title":"Neurology"},{"key":"1958_CR27","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1007\/s10194-007-0387-6","volume":"8","author":"CR Campos","year":"2007","unstructured":"Campos CR, Calderaro M, Scaff M, Conforto AB (2007) Primary headaches and painful spontaneous cervical artery dissection. J Headache Pain 8:180\u2013184. https:\/\/doi.org\/10.1007\/s10194-007-0387-6","journal-title":"J Headache Pain"},{"key":"1958_CR28","doi-asserted-by":"publisher","first-page":"1179","DOI":"10.1007\/s00415-003-0174-5","volume":"250","author":"R Dziewas","year":"2003","unstructured":"Dziewas R, Konrad C, Dr\u00e4ger B et al (2003) Cervical artery dissection\u2013clinical features, risk factors, therapy and outcome in 126 patients. J Neurol 250:1179\u20131184. https:\/\/doi.org\/10.1007\/s00415-003-0174-5","journal-title":"J Neurol"},{"key":"1958_CR29","doi-asserted-by":"publisher","first-page":"1985","DOI":"10.1007\/s10072-017-3084-5","volume":"38","author":"N Giannini","year":"2017","unstructured":"Giannini N, Ulivi L, Maccarrone M et al (2017) Epidemiology and cerebrovascular events related to cervical and intracranial arteries dissection: the experience of the city of Pisa. Neurol Sciences: Official J Italian Neurol Soc Italian Soc Clin Neurophysiol 38:1985\u20131991. https:\/\/doi.org\/10.1007\/s10072-017-3084-5","journal-title":"Neurol Sciences: Official J Italian Neurol Soc Italian Soc Clin Neurophysiol"},{"key":"1958_CR30","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1007\/s10072-020-04651-8","volume":"41","author":"S Vidale","year":"2020","unstructured":"Vidale S (2020) Headache in cervicocerebral artery dissection. Neurological sciences: official journal of the Italian Neurological Society and of the Italian society of. Clin Neurophysiol 41:395\u2013399. https:\/\/doi.org\/10.1007\/s10072-020-04651-8","journal-title":"Clin Neurophysiol"},{"key":"1958_CR31","doi-asserted-by":"publisher","first-page":"112","DOI":"10.5853\/jos.2018.03055","volume":"21","author":"L Mayer","year":"2019","unstructured":"Mayer L, Boehme C, Toell T et al (2019) Local signs and symptoms in spontaneous cervical artery dissection: a single Centre Cohort Study. J Stroke 21:112\u2013115. https:\/\/doi.org\/10.5853\/jos.2018.03055","journal-title":"J Stroke"},{"key":"1958_CR32","doi-asserted-by":"publisher","first-page":"872","DOI":"10.1177\/03331024221079298","volume":"42","author":"L Mayer-Suess","year":"2022","unstructured":"Mayer-Suess L, Frank F, T\u00f6ll T et al (2022) Head\/neck pain characteristics after spontaneous cervical artery dissection in the acute phase and on a long-run. Cephalalgia: Int J Headache 42:872\u2013878. https:\/\/doi.org\/10.1177\/03331024221079298","journal-title":"Cephalalgia: Int J Headache"},{"key":"1958_CR33","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1046\/j.1468-2982.2002.00421.x","volume":"22","author":"F Mainardi","year":"2002","unstructured":"Mainardi F, Maggioni F, Dainese F et al (2002) Spontaneous carotid artery dissection with cluster-like headache. Cephalalgia: Int J Headache 22:557\u2013559. https:\/\/doi.org\/10.1046\/j.1468-2982.2002.00421.x","journal-title":"Cephalalgia: Int J Headache"},{"key":"1958_CR34","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1111\/j.1526-4610.2007.01034.x","volume":"48","author":"A Rigamonti","year":"2008","unstructured":"Rigamonti A, Iurlaro S, Reganati P et al (2008) Cluster headache and internal carotid artery dissection: two cases and review of the literature. Headache 48:467\u2013470. https:\/\/doi.org\/10.1111\/j.1526-4610.2007.01034.x","journal-title":"Headache"},{"key":"1958_CR35","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1111\/j.1468-2982.2004.00905.x","volume":"25","author":"SL Lai","year":"2005","unstructured":"Lai SL, Chang YY, Liu JS, Chen SS (2005) Cluster-like headache from vertebral artery dissection: angiographic evidence of neurovascular activation. Cephalalgia: Int J Headache 25:629\u2013632. https:\/\/doi.org\/10.1111\/j.1468-2982.2004.00905.x","journal-title":"Cephalalgia: Int J Headache"},{"key":"1958_CR36","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1111\/j.1526-4610.2005.05034_2.x","volume":"45","author":"A Rogalewski","year":"2005","unstructured":"Rogalewski A, Evers S (2005) Symptomatic hemicrania continua after internal carotid artery dissection. Headache 45:167\u2013169. https:\/\/doi.org\/10.1111\/j.1526-4610.2005.05034_2.x","journal-title":"Headache"},{"key":"1958_CR37","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1111\/j.1526-4610.2006.00637.x","volume":"47","author":"A Ashkenazi","year":"2007","unstructured":"Ashkenazi A, Abbas MA, Sharma DK, Silberstein SD (2007) Hemicrania continua-like headache associated with internal carotid artery dissection may respond to indomethacin. Headache 47:127\u2013130. https:\/\/doi.org\/10.1111\/j.1526-4610.2006.00637.x","journal-title":"Headache"},{"key":"1958_CR38","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1111\/j.1526-4610.2008.01066.x","volume":"48","author":"N Morelli","year":"2008","unstructured":"Morelli N, Mancuso M, Gori S et al (2008) Vertebral artery dissection onset mimics migraine with aura in a graphic designer. Headache 48:621\u2013624. https:\/\/doi.org\/10.1111\/j.1526-4610.2008.01066.x","journal-title":"Headache"},{"key":"1958_CR39","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1136\/jnnp.59.3.340","volume":"59","author":"G Young","year":"1995","unstructured":"Young G, Humphrey P (1995) Vertebral artery dissection mimicking migraine. J Neurol Neurosurg Psychiatry 59:340\u2013341. https:\/\/doi.org\/10.1136\/jnnp.59.3.340","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"1958_CR40","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1016\/s0303-8467(98)00011-0","volume":"100","author":"IE Silverman","year":"1998","unstructured":"Silverman IE, Wityk RJ (1998) Transient migraine-like symptoms with internal carotid artery dissection. Clin Neurol Neurosurg 100:116\u2013120. https:\/\/doi.org\/10.1016\/s0303-8467(98)00011-0","journal-title":"Clin Neurol Neurosurg"},{"issue":"3","key":"1958_CR41","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1136\/emj.15.3.187","volume":"15","author":"Z Mirza","year":"1998","unstructured":"Mirza Z, Hayward P, Hulbert D (1998) Spontaneous carotid artery dissection presenting as migraine\u2013a diagnosis not to be missed. J Accid Emerg Med May 15(3):187\u2013189. https:\/\/doi.org\/10.1136\/emj.15.3.187","journal-title":"J Accid Emerg Med May"},{"key":"1958_CR42","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1046\/j.1526-4610.1997.3702109.x","volume":"37","author":"RF Duyff","year":"1997","unstructured":"Duyff RF, Snijders CJ, Vanneste JA (1997) Spontaneous bilateral internal carotid artery dissection and migraine: a potential diagnostic delay. Headache 37:109\u2013112. https:\/\/doi.org\/10.1046\/j.1526-4610.1997.3702109.x","journal-title":"Headache"},{"key":"1958_CR43","doi-asserted-by":"publisher","first-page":"3294","DOI":"10.12998\/wjcc.v9.i14.3294","volume":"9","author":"RJ Long","year":"2021","unstructured":"Long RJ, Zhu YS, Wang AP (2021) Cluster headache due to structural lesions: a systematic review of published cases. World J Clin Cases 9:3294\u20133307. https:\/\/doi.org\/10.12998\/wjcc.v9.i14.3294","journal-title":"World J Clin Cases"},{"key":"1958_CR44","doi-asserted-by":"publisher","unstructured":"Debette S, Mazighi M, Bijlenga P et al (2021) ESO guideline for the management of extracranial and intracranial artery dissection. Eur Stroke J Sep 6(3). https:\/\/doi.org\/10.1177\/23969873211046475. XXXIX-LXXXVIII","DOI":"10.1177\/23969873211046475"},{"key":"1958_CR45","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1007\/s10140-008-0770-x","volume":"16","author":"JM Provenzale","year":"2009","unstructured":"Provenzale JM (2009) MRI and MRA for evaluation of dissection of craniocerebral arteries: lessons from the medical literature. Emerg Radiol 16:185\u2013193. https:\/\/doi.org\/10.1007\/s10140-008-0770-x","journal-title":"Emerg Radiol"},{"key":"1958_CR46","doi-asserted-by":"publisher","first-page":"1221","DOI":"10.1212\/WNL.0b013e318251595f","volume":"78","author":"TM Metso","year":"2012","unstructured":"Metso TM, Tatlisumak T, Debette S et al (2012) Migraine in cervical artery dissection and ischemic stroke patients. Neurology 78:1221\u20131228. https:\/\/doi.org\/10.1212\/WNL.0b013e318251595f","journal-title":"Neurology"},{"key":"1958_CR47","doi-asserted-by":"publisher","first-page":"769","DOI":"10.1212\/WNL.0000000000006037","volume":"91","author":"A Compter","year":"2018","unstructured":"Compter A, Schilling S, Vaineau CJ et al (2018) Determinants and outcome of multiple and early recurrent cervical artery dissections. Neurology 91:769\u2013780. https:\/\/doi.org\/10.1212\/WNL.0000000000006037","journal-title":"Neurology"},{"key":"1958_CR48","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1007\/s10194-012-0420-2","volume":"13","author":"H Maruyama","year":"2012","unstructured":"Maruyama H, Nagoya H, Kato Y et al (2012) Spontaneous cervicocephalic arterial dissection with headache and neck pain as the only symptom. J Headache Pain 13:247\u2013253. https:\/\/doi.org\/10.1007\/s10194-012-0420-2","journal-title":"J Headache Pain"},{"key":"1958_CR49","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1046\/j.1468-2982.1992.1205314.x","volume":"12","author":"V Biousse","year":"1992","unstructured":"Biousse V, Woimant F, Amarenco P et al (1992) Pain as the only manifestation of internal carotid artery dissection. Cephalalgia 12:314\u2013317. https:\/\/doi.org\/10.1046\/j.1468-2982.1992.1205314.x","journal-title":"Cephalalgia"},{"key":"1958_CR50","doi-asserted-by":"publisher","first-page":"033310242412302","DOI":"10.1177\/03331024241230247","volume":"44","author":"M Obadia","year":"2024","unstructured":"Obadia M, Nasr N, Volle G et al (2024) Long-term clinical and ultrasound follow-up after transient perivascular inflammation of the carotid artery (TIPIC) syndrome: a multicenter study. Cephalalgia 44:03331024241230247. https:\/\/doi.org\/10.1177\/03331024241230247","journal-title":"Cephalalgia"},{"key":"1958_CR51","doi-asserted-by":"publisher","first-page":"886","DOI":"10.1177\/0333102411401634","volume":"31","author":"PM Rist","year":"2011","unstructured":"Rist PM, Diener HC, Kurth T, Sch\u00fcrks M (2011) Migraine, migraine aura, and cervical artery dissection: a systematic review and meta-analysis. Cephalalgia: Int J Headache 31:886\u2013896. https:\/\/doi.org\/10.1177\/0333102411401634","journal-title":"Cephalalgia: Int J Headache"},{"key":"1958_CR52","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1002\/ana.21871","volume":"67","author":"A Nozari","year":"2010","unstructured":"Nozari A, Dilekoz E, Sukhotinsky I et al (2010) Microemboli may link spreading depression, migraine aura, and patent foramen ovale. Ann Neurol 67:221\u2013229. https:\/\/doi.org\/10.1002\/ana.21871","journal-title":"Ann Neurol"},{"key":"1958_CR53","doi-asserted-by":"publisher","first-page":"333102422114478","DOI":"10.1177\/03331024221144782","volume":"43","author":"BP Martins","year":"2023","unstructured":"Martins BP, Mesquita I, Sousa JM et al (2023) Persistent headache attributed to past cervicocephalic artery dissection: clinical characteristics and contributors to headache persistence. Cephalalgia: Int J Headache 43:3331024221144782. https:\/\/doi.org\/10.1177\/03331024221144782","journal-title":"Cephalalgia: Int J Headache"},{"key":"1958_CR54","doi-asserted-by":"publisher","first-page":"712","DOI":"10.1177\/0333102414520767","volume":"34","author":"HW Schytz","year":"2014","unstructured":"Schytz HW, Ashina M, Magyari M et al (2014) Acute headache and persistent headache attributed to cervical artery dissection: field testing of ICHD-III beta. Cephalalgia: Int J Headache 34:712\u2013716. https:\/\/doi.org\/10.1177\/0333102414520767","journal-title":"Cephalalgia: Int J Headache"},{"key":"1958_CR55","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1159\/000107817","volume":"5","author":"D Leys","year":"1995","unstructured":"Leys D, Th. Moulin TS, Begey S, Chavot D (1995) Follow-Up of patients with history of cervical artery dissection. Cerebrovasc Dis 5:43\u201349. https:\/\/doi.org\/10.1159\/000107817","journal-title":"Cerebrovasc Dis"},{"key":"1958_CR56","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1186\/s10194-022-01479-9","volume":"23","author":"ER Lebedeva","year":"2022","unstructured":"Lebedeva ER, Ushenin AV, Gurary NM et al (2022) Persistent headache after first-ever ischemic stroke: clinical characteristics and factors associated with its development. J Headache Pain 23:103. https:\/\/doi.org\/10.1186\/s10194-022-01479-9","journal-title":"J Headache Pain"},{"key":"1958_CR57","doi-asserted-by":"publisher","first-page":"1442","DOI":"10.1111\/head.13382","volume":"58","author":"J Lai","year":"2018","unstructured":"Lai J, Harrison RA, Plecash A, Field TS (2018) A narrative review of persistent Post-stroke Headache - A New Entry in the International classification of Headache disorders. Headache 58:1442\u20131453. https:\/\/doi.org\/10.1111\/head.13382","journal-title":"Headache"},{"key":"1958_CR58","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1212\/wnl.50.1.203","volume":"50","author":"JM Ferro","year":"1998","unstructured":"Ferro JM, Melo TP, Guerreiro M (1998) Headaches in intracerebral hemorrhage survivors. Neurology 50:203\u2013207. https:\/\/doi.org\/10.1212\/wnl.50.1.203","journal-title":"Neurology"},{"key":"1958_CR59","doi-asserted-by":"publisher","first-page":"1446","DOI":"10.1007\/s00415-010-5539-y","volume":"257","author":"H Naess","year":"2010","unstructured":"Naess H, Lunde L, Brogger J, Waje-Andreassen U (2010) Post-stroke pain on long-term follow-up: the Bergen stroke study. J Neurol 257:1446\u20131452. https:\/\/doi.org\/10.1007\/s00415-010-5539-y","journal-title":"J Neurol"},{"key":"1958_CR60","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1016\/j.jstrokecerebrovasdis.2008.10.004","volume":"18","author":"K Koopman","year":"2009","unstructured":"Koopman K, Uyttenboogaart M, Vroomen PC et al (2009) Long-term sequelae after cerebral venous thrombosis in functionally independent patients. J Stroke Cerebrovasc Diseases: Official J Natl Stroke Association 18:198\u2013202. https:\/\/doi.org\/10.1016\/j.jstrokecerebrovasdis.2008.10.004","journal-title":"J Stroke Cerebrovasc Diseases: Official J Natl Stroke Association"},{"key":"1958_CR61","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1159\/000313608","volume":"30","author":"V Artto","year":"2010","unstructured":"Artto V, Metso TM, Metso AJ et al (2010) Migraine with aura is a risk factor for cervical artery dissection: a case-control study. Cerebrovasc Dis (Basel Switz 30:36\u201340. https:\/\/doi.org\/10.1159\/000313608","journal-title":"Cerebrovasc Dis (Basel Switz"},{"key":"1958_CR62","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1016\/j.jstrokecerebrovasdis.2013.02.014","volume":"22","author":"B Censori","year":"2013","unstructured":"Censori B, Partziguian T, Poloni M (2013) Migraine improves after ischemic stroke. J Stroke Cerebrovasc Diseases: Official J Natl Stroke Association 22:338\u2013342. https:\/\/doi.org\/10.1016\/j.jstrokecerebrovasdis.2013.02.014","journal-title":"J Stroke Cerebrovasc Diseases: Official J Natl Stroke Association"},{"key":"1958_CR63","doi-asserted-by":"publisher","unstructured":"Giuli V, Graziano F, Zini A, et al.\u2026 Italian Project on Stroke in Young Adults (IPSYS) Investigators (2019) Migraine improvement after spontaneous cervical artery dissection the Italian Project on Stroke in Young Adults (IPSYS) Neurological sciences: official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 40:59\u201366. https:\/\/doi.org\/10.1007\/s10072-018-3578-9","DOI":"10.1007\/s10072-018-3578-9"},{"key":"1958_CR64","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1212\/wnl.57.1.130","volume":"57","author":"E Linetsky","year":"2001","unstructured":"Linetsky E, Leker RR, Ben-Hur T (2001) Headache characteristics in patients after migrainous stroke. Neurology 57:130\u2013132. https:\/\/doi.org\/10.1212\/wnl.57.1.130","journal-title":"Neurology"},{"key":"1958_CR65","doi-asserted-by":"publisher","first-page":"251581632095817","DOI":"10.1177\/2515816320958176","volume":"3","author":"JL Brandes","year":"2020","unstructured":"Brandes JL, Klise S, Krege JH et al (2020) Long-term safety and efficacy of lasmiditan for acute treatment of migraine: final results of the GLADIATOR study. Cephalalgia Rep 3:2515816320958176. https:\/\/doi.org\/10.1177\/2515816320958176","journal-title":"Cephalalgia Rep"},{"key":"1958_CR66","doi-asserted-by":"publisher","first-page":"2370","DOI":"10.1212\/WNL.96.15_supplement.2370","volume":"96","author":"J Schim","year":"2021","unstructured":"Schim J, Hutchinson S, Lipton R et al (2021) Rimegepant is safe and tolerable for the Acute treatment of migraine in patients using preventive migraine medications: results from a long-term open-label safety study (2370). Neurology 96:2370. https:\/\/doi.org\/10.1212\/WNL.96.15_supplement.2370","journal-title":"Neurology"},{"key":"1958_CR67","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1186\/s10194-024-01873-5","volume":"25","author":"Z Yang","year":"2024","unstructured":"Yang Z, Wang X, Niu M et al (2024) First real-world study on the effectiveness and tolerability of rimegepant for acute migraine therapy in Chinese patients. J Headache Pain 25:160. https:\/\/doi.org\/10.1186\/s10194-024-01873-5","journal-title":"J Headache Pain"},{"key":"1958_CR68","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1111\/head.13682","volume":"60","author":"J Ailani","year":"2020","unstructured":"Ailani J, Lipton RB, Hutchinson S et al (2020) Long-term safety evaluation of Ubrogepant for the Acute Treatment of Migraine: phase 3, Randomized, 52\u2010Week Extension Trial. Headache 60:141\u2013152. https:\/\/doi.org\/10.1111\/head.13682","journal-title":"Headache"},{"key":"1958_CR69","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1111\/head.14062","volume":"61","author":"C Chiang","year":"2021","unstructured":"Chiang C, Arca KN, Dunn RB et al (2021) Real-world efficacy, tolerability, and safety of ubrogepant. Headache 61:620\u2013627. https:\/\/doi.org\/10.1111\/head.14062","journal-title":"Headache"},{"key":"1958_CR70","doi-asserted-by":"publisher","first-page":"1753","DOI":"10.1177\/0333102419869918","volume":"39","author":"PJ Goadsby","year":"2019","unstructured":"Goadsby PJ, Tepper SJ, Watkins PB et al (2019) Safety and tolerability of ubrogepant following intermittent, high-frequency dosing: Randomized, placebo-controlled trial in healthy adults. Cephalalgia 39:1753\u20131761. https:\/\/doi.org\/10.1177\/0333102419869918","journal-title":"Cephalalgia"},{"key":"1958_CR71","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1016\/S1474-4422(17)30435-0","volume":"17","author":"A Charles","year":"2018","unstructured":"Charles A (2018) The pathophysiology of migraine: implications for clinical management. Lancet Neurol 17:174\u2013182. https:\/\/doi.org\/10.1016\/S1474-4422(17)30435-0","journal-title":"Lancet Neurol"},{"key":"1958_CR72","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1111\/j.1526-4610.1989.hed2909560.x","volume":"29","author":"J D\u2019Anglejan-Chatillon","year":"1989","unstructured":"D\u2019Anglejan-Chatillon J, Ribeiro V, Mas JL et al (1989) Migraine\u2013a risk factor for dissection of cervical arteries. Headache 29:560\u2013561. https:\/\/doi.org\/10.1111\/j.1526-4610.1989.hed2909560.x","journal-title":"Headache"},{"key":"1958_CR73","doi-asserted-by":"publisher","first-page":"904","DOI":"10.1177\/23969873231191860","volume":"8","author":"Z Sun","year":"2023","unstructured":"Sun Z, Kleine-Borgmann J, Suh J et al (2023) Migraine and the risk of cervical artery dissection: a systematic review and meta-analysis. Eur Stroke J 8:904\u2013914. https:\/\/doi.org\/10.1177\/23969873231191860","journal-title":"Eur Stroke J"},{"key":"1958_CR74","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1212\/NXG.0000000000000653","volume":"8","author":"I Daghals","year":"2022","unstructured":"Daghals I, Sargurupremraj M, Danning R et al (2022) Migraine, Stroke, and cervical arterial dissection: Shared Genetics for a Triad of Brain disorders with vascular involvement. Neurol Genet 8:653. https:\/\/doi.org\/10.1212\/NXG.0000000000000653","journal-title":"Neurol Genet"},{"key":"1958_CR75","doi-asserted-by":"publisher","unstructured":"Freilinger T, Anttila V, Vries B, et al (2012) Genome-wide association analysis identifies susceptibility loci for migraine without aura.\u2026 International Headache Genetics Consortium 44:777\u2013782. https:\/\/doi.org\/10.1038\/ng.2307","DOI":"10.1038\/ng.2307"},{"key":"1958_CR76","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1038\/ng.3154","volume":"47","author":"S Debette","year":"2015","unstructured":"Debette S, Kamatani Y, Metso TM et al (2015) Common variation in PHACTR1 is associated with susceptibility to cervical artery dissection. Nat Genet 47:78\u201383. https:\/\/doi.org\/10.1038\/ng.3154","journal-title":"Nat Genet"},{"key":"1958_CR77","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1016\/j.cell.2017.06.049","volume":"170","author":"RM Gupta","year":"2017","unstructured":"Gupta RM, Hadaya J, Trehan A et al (2017) A Genetic Variant Associated with five vascular diseases is a Distal Regulator of Endothelin-1 gene expression. Cell 170:522\u201353315. https:\/\/doi.org\/10.1016\/j.cell.2017.06.049","journal-title":"Cell"},{"key":"1958_CR78","doi-asserted-by":"publisher","first-page":"964","DOI":"10.1038\/s41588-023-01410-1","volume":"55","author":"D Adlam","year":"2023","unstructured":"Adlam D, Berrandou TE, Georges A et al (2023) Genome-wide association meta-analysis of spontaneous coronary artery dissection identifies risk variants and genes related to artery integrity and tissue-mediated coagulation. Nat Genet 55:964\u2013972. https:\/\/doi.org\/10.1038\/s41588-023-01410-1","journal-title":"Nat Genet"},{"key":"1958_CR79","doi-asserted-by":"publisher","first-page":"1472","DOI":"10.1161\/ATVBAHA.115.305534","volume":"35","author":"M Beaudoin","year":"2015","unstructured":"Beaudoin M, Gupta RM, Won HH et al (2015) Myocardial infarction-Associated SNP at 6p24 interferes with MEF2 binding and associates with PHACTR1 expression levels in human coronary arteries. Arterioscler Thromb Vasc Biol 35:1472\u20131479. https:\/\/doi.org\/10.1161\/ATVBAHA.115.305534","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"1958_CR80","doi-asserted-by":"publisher","first-page":"002327","DOI":"10.1161\/CIRCGEN.118.002327","volume":"11","author":"X Wang","year":"2018","unstructured":"Wang X, Musunuru K (2018) Confirmation of causal rs9349379- PHACTR1 expression quantitative trait Locus in Human-Induced Pluripotent Stem Cell endothelial cells. Circulation Genomic Precision Med 11:002327. https:\/\/doi.org\/10.1161\/CIRCGEN.118.002327","journal-title":"Circulation Genomic Precision Med"},{"key":"1958_CR81","doi-asserted-by":"publisher","unstructured":"Rubin S, Bougaran P, Martin S et al (2022) PHACTR-1 (phosphatase and actin Regulator 1. Deficiency in either endothelial or smooth muscle cells does not predispose mice to Nonatherosclerotic Arteriopathies in 3 transgenic mice arteriosclerosis, thrombosis, and vascular biology. 42:597\u2013609. https:\/\/doi.org\/10.1161\/ATVBAHA.122.317431","DOI":"10.1161\/ATVBAHA.122.317431"},{"key":"1958_CR82","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1111\/j.1526-4610.2007.00958.x","volume":"48","author":"K Imamura","year":"2008","unstructured":"Imamura K, Takeshima T, Fusayasu E, Nakashima K (2008) Increased plasma matrix metalloproteinase-9 levels in migraineurs. Headache 48:135\u2013139. https:\/\/doi.org\/10.1111\/j.1526-4610.2007.00958.x","journal-title":"Headache"},{"key":"1958_CR83","doi-asserted-by":"publisher","first-page":"698","DOI":"10.1111\/j.1526-4610.2006.00641.x","volume":"47","author":"R Leira","year":"2007","unstructured":"Leira R, Sobrino T, Rodr\u00edguez-Y\u00e1\u00f1ez M et al (2007) Mmp-9 immunoreactivity in acute migraine. Headache 47:698\u2013702. https:\/\/doi.org\/10.1111\/j.1526-4610.2006.00641.x","journal-title":"Headache"},{"key":"1958_CR84","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1159\/000098331","volume":"23","author":"B Guillon","year":"2007","unstructured":"Guillon B, Peynet J, Bertrand M et al (2007) Do extracellular-matrix-regulating enzymes play a role in cervical artery dissection? Cerebrovascular diseases (Basel. Switzerland 23:299\u2013303. https:\/\/doi.org\/10.1159\/000098331","journal-title":"Switzerland"},{"key":"1958_CR85","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1111\/head.12798","volume":"56","author":"J Mawet","year":"2016","unstructured":"Mawet J, Debette S, Bousser MG, Ducros A (2016) The Link between Migraine, reversible cerebral vasoconstriction syndrome and cervical artery dissection. Headache 56:645\u2013656. https:\/\/doi.org\/10.1111\/head.12798","journal-title":"Headache"},{"key":"1958_CR86","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1161\/STROKEAHA.120.031579","volume":"52","author":"S Bonacina","year":"2021","unstructured":"Bonacina S, Grassi M, Zedde M et al (2021) Clinical features of patients with cervical artery dissection and fibromuscular dysplasia. Stroke 52:821\u2013829. https:\/\/doi.org\/10.1161\/STROKEAHA.120.031579","journal-title":"Stroke"},{"key":"1958_CR87","doi-asserted-by":"publisher","first-page":"1006367","DOI":"10.1371\/journal.pgen.1006367","volume":"12","author":"SR Kiando","year":"2016","unstructured":"Kiando SR, Tucker NR, Castro-Vega LJ et al (2016) PHACTR1 is a genetic susceptibility locus for Fibromuscular Dysplasia supporting its Complex genetic pattern of inheritance. PLoS Genet 12:1006367. https:\/\/doi.org\/10.1371\/journal.pgen.1006367","journal-title":"PLoS Genet"},{"key":"1958_CR88","doi-asserted-by":"publisher","first-page":"1537","DOI":"10.1161\/CIRCULATIONAHA.110.000125","volume":"123","author":"S Debette","year":"2011","unstructured":"Debette S, Metso T, Pezzini A et al (2011) Association of vascular risk factors with cervical artery dissection and ischemic stroke in young adults. Circulation 123:1537\u20131544. https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.110.000125","journal-title":"Circulation"},{"key":"1958_CR89","doi-asserted-by":"publisher","first-page":"1411","DOI":"10.1016\/j.jacc.2023.07.021","volume":"82","author":"Q Le Grand","year":"2023","unstructured":"Le Grand Q, Ecker Ferreira L, Metso TM et al (2023) Genetic insights on the relation of vascular risk factors and cervical artery dissection. J Am Coll Cardiol 82:1411\u20131423. https:\/\/doi.org\/10.1016\/j.jacc.2023.07.021","journal-title":"J Am Coll Cardiol"},{"key":"1958_CR90","doi-asserted-by":"publisher","unstructured":"Finocchi C, Sassos D (2017) Headache and arterial hypertension. Neurological sciences: official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 38:67\u201372. https:\/\/doi.org\/10.1007\/s10072-017-2893-x","DOI":"10.1007\/s10072-017-2893-x"},{"key":"1958_CR91","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1177\/1358863X241252444","volume":"29","author":"BJ Wells","year":"2024","unstructured":"Wells BJ, Wood MJ, O\u2019Duffy AE et al (2024) Migraine headache in patients with spontaneous coronary artery dissection: a report of the iSCAD Registry. Vascular Med 29:286\u2013295","journal-title":"Vascular Med"}],"container-title":["The Journal of Headache and Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s10194-025-01958-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s10194-025-01958-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s10194-025-01958-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T07:57:25Z","timestamp":1738828645000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejournalofheadacheandpain.biomedcentral.com\/articles\/10.1186\/s10194-025-01958-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,6]]},"references-count":91,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["1958"],"URL":"https:\/\/doi.org\/10.1186\/s10194-025-01958-9","relation":{},"ISSN":["1129-2377"],"issn-type":[{"value":"1129-2377","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,6]]},"assertion":[{"value":"3 December 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 January 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 February 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"DD has no competing interests; SB has no competing interests; JM has received financial supports for boards and meeting presentations from Lilly, Abbvie, TEVA, Lundbeck, Pfizer and Orion Pharma. He has received travel fees for congress from Ipsen Pharmaceuticals, Abbvie, Lundbeck, SOS Oxygen and Dr Reddy\u2019s.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"28"}}