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MW was supported by personal grants from the Netherlands Organization for Scientific Research (VIDI Grant no. 91717337 and Aspasia grant). TH received support from the Dutch Heart Foundation and the Netherlands Organisation for Scientific Research (NWO), as part of their joint strategic research programme: \u201cEarlier recognition of cardiovascular diseases\u201d. AW and GT and IB report grant support by the European Community (101070917), Stichting Dioraphte (20010407), and the Clayco foundation. In addition, IB reports independent research support from the Dutch Heart Foundation (2020T065), and GT reports additional grants or consultancy support from Abbvie, Novartis, Lilly, Lundbeck, Organon, Pfizer, Teva, and independent support from the Dutch Research Council, Heart Foundation, Dutch Brain Foundation. AMB received honoraria and research\/travel grants from Allergan\/AbbVie, Amgen\/Novartis, Eli Lilly, Pfizer, Satsuma, Teva, and Tonix, and independent support from the Dutch Research Council and ZonMw.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"37"}}