{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T21:16:39Z","timestamp":1790975799379,"version":"4.1.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T00:00:00Z","timestamp":1750377600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T00:00:00Z","timestamp":1750377600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100007465","name":"UiT The Arctic University of Norway","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100007465","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Headache Pain"],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background and purpose<\/jats:title>\n            <jats:p>Migraine considerably affects women during their reproductive years. This cross-sectional study uses data from the Norwegian Women and Health study (NOWAC) and investigates the typical age at migraine onset and cessation in women and assesses how reproductive milestones affect migraine patterns.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>4825 women with a history of migraine were included in the study. Participants completed a questionnaire that procured detailed information on their migraine characteristics and reproductive histories.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Average ages at migraine onset and cessation were 27.8 and 49.7 years, respectively. Migraine onset after age 50 was reported in 9.2% of the participants. Although 80.7% reported cessation before age 60, 46.3% continued to experience migraines postmenopause. Women with migraine with aura were more likely to report migraine onset before menarche than those with migraine without aura.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Migraines usually resolve during the fifth decade of a woman\u2019s life and menstruation cessation does not necessarily equate to migraine cessation, as almost half of the women continued to experience migraines postmenopause, and one in five after 60 years. Migraine symptom persistence in a significant proportion of postmenopausal women underscores the need for continued management and research on the factors influencing migraine prevalence in later life stages.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Graphical Abstract<\/jats:title>\n            <jats:p>Age at last migraine attack by migraine type. Orange dotted line represents mean age at menopause.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/s10194-025-02083-3","type":"journal-article","created":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T08:55:13Z","timestamp":1750409713000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Migraine through puberty and menopausal transition\u2014data from the population-based Norwegian Women and Health study (NOWAC)"],"prefix":"10.1186","volume":"26","author":[{"given":"Nora Stensland","family":"Bugge","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kjersti Gr\u00f8tta","family":"Vetvik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl Bj\u00f8rnar","family":"Alstadhaug","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tonje","family":"Braaten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,6,20]]},"reference":[{"key":"2083_CR1","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1186\/s10194-022-01402-2","volume":"23","author":"LJ Stovner","year":"2022","unstructured":"Stovner LJ, Hagen K, Linde M et al (2022) The global prevalence of headache: an update, with analysis of the influences of methodological factors on prevalence estimates. 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The study has been licensed by the Norwegian Data Inspectorate (2002\/2241) and approved by the Regional Committee for Medical and Health Research Ethics (REC-635219).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"KGV has received honoraria for lecturing and\/or participation in advisory boards from Novartis, TEVA, Roche, Pfizer, Lundbeck, Eli Lilly and Abbvie.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"145"}}