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The main online databases were accessed in January 2022 without time constraints. All clinical studies investigating the use of synthetic grafts for MPFL reconstruction were accessed. Revision settings were not considered. Only articles reporting data on patients with recurrent patellofemoral instability were eligible. Studies regarding congenital or acute patellofemoral dislocation were excluded. Only studies performing a follow-up longer than 24\u00a0months were considered.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Data on 199 patients [mean age 22.3 (range 19.0\u201328.0) years] were collected. The mean follow-up was 60.5 (39.0\u2013142.8) months. All the scores of interest improved at last follow-up: Kujala (+\u200924.8; <jats:italic>P<\/jats:italic>\u2009=\u20090.0002), Lysholm (+\u200942.0; <jats:italic>P<\/jats:italic>\u2009=\u20090.02), Tegner (+\u20091.2; <jats:italic>P<\/jats:italic>\u2009=\u20090.03), IKDC (+\u200920.9; <jats:italic>P<\/jats:italic>\u2009=\u20090.02). Post-operatively, a positive apprehension test was detected in 6.1% (7\/115) of patients, and a sensation of instability was reported by 1.5% (3\/199) of patients. The rate of re-dislocations was 2.5% (5 of 199 patients), and revision procedures were performed in less than 1% (1 of 199) of patients.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Synthetic graft may be reliable and feasible for primary MPFL reconstruction in patients with recurrent patellofemoral instability.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s10195-022-00660-9","type":"journal-article","created":{"date-parts":[[2022,8,22]],"date-time":"2022-08-22T16:03:50Z","timestamp":1661184230000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Synthetic graft for medial patellofemoral ligament reconstruction: a systematic review"],"prefix":"10.1186","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7220-1221","authenticated-orcid":false,"given":"Filippo","family":"Migliorini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f6rg","family":"Eschweiler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"Spiezia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Knobe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Hildebrand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Maffulli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,8,22]]},"reference":[{"issue":"4","key":"660_CR1","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1249\/MSS.0b013e318160740f","volume":"40","author":"PMV Sillanp\u00e4\u00e4","year":"2008","unstructured":"Sillanp\u00e4\u00e4 PMV, Iivonen T et al (2008) Incidence and risk factors of acute traumatic primary patellar dislocation. 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