{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T02:52:43Z","timestamp":1778899963250,"version":"3.51.4"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,6,10]],"date-time":"2019-06-10T00:00:00Z","timestamp":1560124800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,6,10]],"date-time":"2019-06-10T00:00:00Z","timestamp":1560124800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012107","name":"Waterloo Foundation","doi-asserted-by":"publisher","award":["918-1234"],"award-info":[{"award-number":["918-1234"]}],"id":[{"id":"10.13039\/100012107","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MR\/K51347\/1"],"award-info":[{"award-number":["MR\/K51347\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MR\/L011166\/1"],"award-info":[{"award-number":["MR\/L011166\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MR\/N022572\/1"],"award-info":[{"award-number":["MR\/N022572\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["G0801418"],"award-info":[{"award-number":["G0801418"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["G0800509"],"award-info":[{"award-number":["G0800509"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001262","name":"Baily Thomas Charitable Fund","doi-asserted-by":"publisher","award":["2314\/1"],"award-info":[{"award-number":["2314\/1"]}],"id":[{"id":"10.13039\/501100001262","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["5UO1MH101724"],"award-info":[{"award-number":["5UO1MH101724"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012068","name":"Health and Care Research Wales","doi-asserted-by":"crossref","award":["Welsh Government, 507556"],"award-info":[{"award-number":["Welsh Government, 507556"]}],"id":[{"id":"10.13039\/100012068","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["ISSF"],"award-info":[{"award-number":["ISSF"]}],"id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["503147"],"award-info":[{"award-number":["503147"]}],"id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neurodevelop Disord"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1186\/s11689-019-9271-3","type":"journal-article","created":{"date-parts":[[2019,6,10]],"date-time":"2019-06-10T16:02:44Z","timestamp":1560182564000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Using kinematic analyses to explore sensorimotor control impairments in children with 22q11.2 deletion syndrome"],"prefix":"10.1186","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9791-7813","authenticated-orcid":false,"given":"Adam C.","family":"Cunningham","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liam","family":"Hill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Mon-Williams","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathryn J.","family":"Peall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David E. J.","family":"Linden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeremy","family":"Hall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J.","family":"Owen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marianne B. M.","family":"van den Bree","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,6,10]]},"reference":[{"issue":"8","key":"9271_CR1","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1002\/pd.4613","volume":"35","author":"FR Grati","year":"2015","unstructured":"Grati FR, Gomes DM, Ferreira JCPB, Dupont C, Alesi V, Gouas L, et al. Prevalence of recurrent pathogenic microdeletions and microduplications in over 9500 pregnancies. Prenat Diagn. 2015;35(8):801\u20139.","journal-title":"Prenat Diagn"},{"key":"9271_CR2","doi-asserted-by":"publisher","first-page":"15071","DOI":"10.1038\/nrdp.2015.71","volume":"1","author":"DM McDonald-McGinn","year":"2015","unstructured":"McDonald-McGinn DM, Sullivan KE, Marino B, Philip N, Swillen A, Vorstman JAS, et al. 22q11.2 deletion syndrome. Nat Rev Dis Primer. 2015;1:15071.","journal-title":"Nat Rev Dis Primer"},{"issue":"01","key":"9271_CR3","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1192\/bjp.2017.6","volume":"212","author":"A Cunningham","year":"2017","unstructured":"Cunningham A, Delport S, Cumines W, Busse M, Linden D, Hall J, et al. Developmental coordination disorder, psychopathology and IQ in 22q11.2 deletion syndrome. Br J Psychiatry. 2017;212(01):27\u201333.","journal-title":"Br J Psychiatry"},{"issue":"3","key":"9271_CR4","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1111\/dmcn.14132","volume":"61","author":"R Blank","year":"2019","unstructured":"Blank R, Barnett AL, Cairney J, Green D, Kirby A, Polatajko H, et al. International clinical practice recommendations on the definition, diagnosis, assessment, intervention, and psychosocial aspects of developmental coordination disorder. Dev Med Child Neurol. 2019;61(3):242\u201385.","journal-title":"Dev Med Child Neurol"},{"issue":"2","key":"9271_CR5","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1097\/01.DBP.0000267554.96081.12","volume":"28","author":"NJ Roizen","year":"2007","unstructured":"Roizen NJ, Antshel KM, Fremont W, AbdulSabur N, Higgins AM, Shprintzen RJ, et al. 22q11.2DS deletion syndrome: developmental milestones in infants and toddlers. J Dev Behav Pediatr. 2007;28(2):119\u201324.","journal-title":"J Dev Behav Pediatr"},{"issue":"3","key":"9271_CR6","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1016\/j.neulet.2006.02.001","volume":"399","author":"Joel P. Bish","year":"2006","unstructured":"Bish JP, Pendyal A, Ding L, Ferrante H, Nguyen V, McDonald-McGinn D, et al. Specific cerebellar reductions in children with chromosome 22q11.2 deletion syndrome. Neurosci Lett. 2006\/03\/07. 2006;399(3):245\u2013248.","journal-title":"Neuroscience Letters"},{"issue":"2","key":"9271_CR7","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/j.biopsych.2014.10.025","volume":"78","author":"JE Schmitt","year":"2014","unstructured":"Schmitt JE, Vandekar S, Yi J, Calkins ME, Ruparel K, Roalf DR, et al. Aberrant cortical morphometry in the 22q11.2 deletion syndrome. Biol Psychiatry. 2014;78(2):135\u201343.","journal-title":"Biol Psychiatry"},{"issue":"12","key":"9271_CR8","doi-asserted-by":"publisher","first-page":"2082","DOI":"10.1002\/mds.21103","volume":"21","author":"C Sobin","year":"2006","unstructured":"Sobin C, Monk SH, Kiley-Brabeck K, Khuri J, Karayiorgou M. Neuromotor deficits in children with the 22q11 deletion syndrome. Mov Disord Off J Mov Disord Soc. 2006;21(12):2082\u20139.","journal-title":"Mov Disord Off J Mov Disord Soc"},{"issue":"2","key":"9271_CR9","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1016\/j.ridd.2011.10.004","volume":"33","author":"S Duijff","year":"2012","unstructured":"Duijff S, Klaassen P, Beemer F, Swanenburg de Veye H, Vorstman J, Sinnema G. Intelligence and visual motor integration in 5-year-old children with 22q11-deletion syndrome. Res Dev Disabil. 2012 Mar;33(2):334\u201340.","journal-title":"Res Dev Disabil"},{"issue":"4","key":"9271_CR10","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1016\/j.jpeds.2010.04.073","volume":"157","author":"NJ Roizen","year":"2011","unstructured":"Roizen NJ, Higgins AM, Antshel KM, Fremont W, Shprintzen R, Kates WR. 22q11.2 deletion syndrome: are motor deficits more than expected for IQ level? J Pediatr. 2011;157(4):658\u201361.","journal-title":"J Pediatr"},{"issue":"6","key":"9271_CR11","first-page":"532","volume":"15","author":"K Van Aken","year":"2009","unstructured":"Van Aken K, Caeyenberghs K, Smits-Engelsman B, Swillen A. The motor profile of primary school-age children with a 22q11.2 deletion syndrome (22q11.2DS) and an age- and IQ-matched control group. Child Neuropsychol J Norm Abnorm Dev Child Adolesc. 2009;15(6):532\u201342.","journal-title":"Child Neuropsychol J Norm Abnorm Dev Child Adolesc"},{"issue":"5","key":"9271_CR12","doi-asserted-by":"publisher","first-page":"1495","DOI":"10.1016\/j.ridd.2012.03.023","volume":"33","author":"SA Howley","year":"2012","unstructured":"Howley SA, Prasad SE, Pender NP, Murphy KC. Relationship between reaction time, fine motor control, and visual-spatial perception on vigilance and visual-motor tasks in 22q11.2 deletion syndrome. Res Dev Disabil. 2012;33(5):1495\u2013502.","journal-title":"Res Dev Disabil"},{"issue":"6","key":"9271_CR13","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1176\/appi.ajp.2013.13070864","volume":"171","author":"Maude Schneider","year":"2014","unstructured":"Schneider M, Debban\u00e9 M, Bassett AS, Chow EWC, Fung WLA, van den Bree MBM, et al. Psychiatric disorders from childhood to adulthood in 22q11.2 deletion syndrome: Results from the international consortium on brain and behavior in 22q11.2 deletion syndrome. Am J Psychiatry. 2014\/03\/01. 2014;171(6):627\u2013639.","journal-title":"American Journal of Psychiatry"},{"issue":"6","key":"9271_CR14","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1177\/1362361311418692","volume":"16","author":"N Papadopoulos","year":"2012","unstructured":"Papadopoulos N, McGinley J, Tonge B, Bradshaw J, Saunders K, Murphy A, et al. Motor proficiency and emotional\/behavioural disturbance in autism and Asperger\u2019s disorder: another piece of the neurological puzzle? Autism. 2012;16(6):627\u201340.","journal-title":"Autism."},{"issue":"3","key":"9271_CR15","doi-asserted-by":"publisher","first-page":"768","DOI":"10.1016\/j.ridd.2010.01.019","volume":"31","author":"K Van Aken","year":"2010","unstructured":"Van Aken K, Swillen A, Beirinckx M, Janssens L, Caeyenberghs K, Smits-Engelsman B. Kinematic movement strategies in primary school children with 22q11 . 2 deletion syndrome compared to age- and IQ-matched controls during visuo-manual tracking. Res Dev Disabil. 2010;31(3):768\u201376.","journal-title":"Res Dev Disabil"},{"issue":"3","key":"9271_CR16","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1016\/j.ridd.2010.01.002","volume":"31","author":"K Van Aken","year":"2010","unstructured":"Van Aken K, Swillen A, Beirinckx M, Janssens L, Caeyenberghs K, Smits-Engelsman B. Prospective control abilities during visuo-manual tracking in children with 22q11.2 deletion syndrome compared to age- and IQ-matched controls. Res Dev Disabil. 2010 May;31(3):634\u201341.","journal-title":"Res Dev Disabil"},{"issue":"1","key":"9271_CR17","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1192\/bjp.bp.113.132324","volume":"204","author":"Maria Niarchou","year":"2014","unstructured":"Niarchou M, Zammit S, van Goozen SH, Thapar A, Tierling HM, Owen MJ, et al. Psychopathology and cognition in children with 22q11.2 deletion syndrome. Br J Psychiatry. 2013\/10\/12. 2014;204(1):46\u201354.","journal-title":"British Journal of Psychiatry"},{"issue":"2","key":"9271_CR18","doi-asserted-by":"publisher","first-page":"e88692","DOI":"10.1371\/journal.pone.0088692","volume":"9","author":"I Flatters","year":"2014","unstructured":"Flatters I, Hill LJB, Williams JHG, Barber SE, Mon-Williams M. Manual control age and sex differences in 4 to 11 year old children. Holmes NP, editor. PLoS One. 2014;9(2):e88692.","journal-title":"PLoS One"},{"issue":"1","key":"9271_CR19","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1016\/j.jneumeth.2009.07.025","volume":"184","author":"PR Culmer","year":"2009","unstructured":"Culmer PR, Levesley MC, Mon-Williams M, Williams JHG. A new tool for assessing human movement: the kinematic assessment tool. J Neurosci Methods. 2009;184(1):184\u201392.","journal-title":"J Neurosci Methods"},{"key":"9271_CR20","volume-title":"WASI: Wechsler abbreviated scale of intelligence. WASI. Psychological corporation","author":"D Wechsler","year":"1999","unstructured":"Wechsler D. WASI: Wechsler abbreviated scale of intelligence. WASI. Psychological corporation; 1999."},{"key":"9271_CR21","volume-title":"Social Communication Questionnaire","author":"M Rutter","year":"2003","unstructured":"Rutter M, Bailey A, Lord C. Social Communication Questionnaire. Los Angeles, CA: Western Psychological Services; 2003."},{"issue":"04","key":"9271_CR22","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1017\/S003329170003498X","volume":"25","author":"A Angold","year":"2009","unstructured":"Angold A, Prendergast M, Cox A, Harrington R, Simonoff E, Rutter M. The child and adolescent psychiatric assessment (CAPA). Psychol Med. 2009;25(04):739.","journal-title":"Psychol Med"},{"key":"9271_CR23","unstructured":"Development Core Team R. R: A Language and Environment for Statistical Computing. Vol. 0, R Foundation for Statistical Computing Vienna Austria. 2011. p. {ISBN} 3\u2013900051\u201307-0."},{"issue":"9","key":"9271_CR24","doi-asserted-by":"publisher","first-page":"2907","DOI":"10.1007\/s00221-014-3947-4","volume":"232","author":"I Flatters","year":"2014","unstructured":"Flatters I, Mushtaq F, Hill LJB, Holt RJ, Wilkie RM, Mon-Williams M. The relationship between a child\u2019s postural stability and manual dexterity. Exp Brain Res. 2014;232(9):2907\u201317.","journal-title":"Exp Brain Res"},{"issue":"10","key":"9271_CR25","doi-asserted-by":"publisher","first-page":"1088","DOI":"10.1016\/j.biopsych.2006.04.003","volume":"60","author":"C Klein","year":"2006","unstructured":"Klein C, Wendling K, Huettner P, Ruder H, Peper M. Intra-subject variability in attention-deficit hyperactivity disorder. Biol Psychiatry. 2006;60(10):1088\u201397.","journal-title":"Biol Psychiatry"},{"issue":"1","key":"9271_CR26","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1017\/S1355617714001076","volume":"21","author":"M Musso","year":"2015","unstructured":"Musso M, Westervelt HJ, Long JD, Morgan E, Woods SP, Smith MM, et al. Intra-individual variability in prodromal Huntington disease and its relationship to genetic burden. J Int Neuropsychol Soc JINS. 2015;21(1):8\u201321.","journal-title":"J Int Neuropsychol Soc JINS"},{"issue":"1","key":"9271_CR27","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/j.neulet.2008.06.004","volume":"441","author":"RM Camicioli","year":"2008","unstructured":"Camicioli RM, Wieler M, de Frias CM, Martin WRW. Early, untreated Parkinson\u2019s disease patients show reaction time variability. Neurosci Lett. 2008;441(1):77\u201380.","journal-title":"Neurosci Lett"},{"issue":"9","key":"9271_CR28","doi-asserted-by":"publisher","first-page":"796","DOI":"10.1111\/j.1467-9280.2007.01982.x","volume":"18","author":"DL Gilden","year":"2007","unstructured":"Gilden DL, Hancock H. Response variability in attention-deficit disorders. Psychol Sci. 2007;18(9):796\u2013802.","journal-title":"Psychol Sci"},{"issue":"6","key":"9271_CR29","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1037\/a0024479","volume":"25","author":"SK Helps","year":"2011","unstructured":"Helps SK, Broyd SJ, Bitsakou P, Sonuga-Barke EJS. Identifying a distinctive familial frequency band in reaction time fluctuations in ADHD. Neuropsychology. 2011;25(6):711\u20139.","journal-title":"Neuropsychology."},{"issue":"1","key":"9271_CR30","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1007\/s00221-003-1403-y","volume":"150","author":"JL Contreras-Vidal","year":"2003","unstructured":"Contreras-Vidal JL, Buch ER. Effects of Parkinson\u2019s disease on visuomotor adaptation. Exp Brain Res. 2003;150(1):25\u201332.","journal-title":"Exp Brain Res"},{"issue":"11","key":"9271_CR31","doi-asserted-by":"publisher","first-page":"1720","DOI":"10.1002\/mds.26672","volume":"31","author":"A Castagna","year":"2016","unstructured":"Castagna A, Frittoli S, Ferrarin M, Del Sorbo F, Romito LM, Elia AE, et al. Quantitative gait analysis in parkin disease: possible role of dystonia. Mov Disord. 2016;31(11):1720\u20138.","journal-title":"Mov Disord"},{"issue":"3","key":"9271_CR32","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1002\/ajmg.a.36928","volume":"167","author":"E Boot","year":"2015","unstructured":"Boot E, Butcher NJ, van Amelsvoort TAMJ, Lang AE, Marras C, Pondal M, et al. Movement disorders and other motor abnormalities in adults with 22q11.2 deletion syndrome. Am J Med Genet A. 2015;167(3):639\u201345.","journal-title":"Am J Med Genet A"},{"issue":"4","key":"9271_CR33","doi-asserted-by":"publisher","first-page":"1351","DOI":"10.1016\/j.ridd.2011.01.041","volume":"32","author":"A Kirby","year":"2011","unstructured":"Kirby A, Edwards L, Sugden D. Emerging adulthood in developmental co-ordination disorder: parent and young adult perspectives. Res Dev Disabil. 2011;32(4):1351\u201360.","journal-title":"Res Dev Disabil"},{"issue":"4","key":"9271_CR34","doi-asserted-by":"publisher","first-page":"1357","DOI":"10.1016\/j.ridd.2013.01.003","volume":"34","author":"A Kirby","year":"2013","unstructured":"Kirby A, Williams N, Thomas M, Hill EL. Self-reported mood, general health, wellbeing and employment status in adults with suspected DCD. Res Dev Disabil. 2013;34(4):1357\u201364.","journal-title":"Res Dev Disabil"}],"container-title":["Journal of Neurodevelopmental Disorders"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s11689-019-9271-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s11689-019-9271-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s11689-019-9271-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,8]],"date-time":"2020-06-08T23:04:27Z","timestamp":1591657467000},"score":1,"resource":{"primary":{"URL":"https:\/\/jneurodevdisorders.biomedcentral.com\/articles\/10.1186\/s11689-019-9271-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,10]]},"references-count":34,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["9271"],"URL":"https:\/\/doi.org\/10.1186\/s11689-019-9271-3","relation":{},"ISSN":["1866-1947","1866-1955"],"issn-type":[{"value":"1866-1947","type":"print"},{"value":"1866-1955","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,10]]},"assertion":[{"value":"19 October 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 May 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 June 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The study was approved by NHS Wales Research Ethics committee (ref: 09\/WSE04\/22). All participants were recruited via UK Medical Genetics clinics, word of mouth, and advertisements through 22q11.2DS charities, using protocols approved by the NHS Ethics and Research and Development committees. Informed written consent was obtained prior to recruitment from carers of the children, and the children themselves where appropriate.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"8"}}