{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T01:28:26Z","timestamp":1794360506536,"version":"4.9.0"},"reference-count":81,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,10,29]],"date-time":"2018-10-29T00:00:00Z","timestamp":1540771200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Health Research Board","award":["HRB\/MRCG-2016-20"],"award-info":[{"award-number":["HRB\/MRCG-2016-20"]}]},{"DOI":"10.13039\/501100001602","name":"Science Foundation Ireland","doi-asserted-by":"crossref","award":["SFI 16\/RI\/3701"],"award-info":[{"award-number":["SFI 16\/RI\/3701"]}],"id":[{"id":"10.13039\/501100001602","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Proteom"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1186\/s12014-018-9212-2","type":"journal-article","created":{"date-parts":[[2018,10,28]],"date-time":"2018-10-28T22:35:31Z","timestamp":1540766131000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Proteomic profiling of liver tissue from the mdx-4cv mouse model of Duchenne muscular dystrophy"],"prefix":"10.1186","volume":"15","author":[{"given":"Sandra","family":"Murphy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margit","family":"Zweyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Henry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Meleady","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rustam R.","family":"Mundegar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dieter","family":"Swandulla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kay","family":"Ohlendieck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,10,29]]},"reference":[{"key":"9212_CR1","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1146\/annurev-genom-090314-025003","volume":"16","author":"S Guiraud","year":"2015","unstructured":"Guiraud S, Aartsma-Rus A, Vieira NM, Davies KE, van Ommen GJ, Kunkel LM. The pathogenesis and therapy of muscular dystrophies. Annu Rev Genom Hum Genet. 2015;16:281\u2013308.","journal-title":"Annu Rev Genom Hum Genet"},{"key":"9212_CR2","doi-asserted-by":"publisher","first-page":"2266","DOI":"10.1016\/j.biocel.2013.05.001","volume":"45","author":"J Shin","year":"2013","unstructured":"Shin J, Tajrishi MM, Ogura Y, Kumar A. Wasting mechanisms in muscular dystrophy. Int J Biochem Cell Biol. 2013;45:2266\u201379.","journal-title":"Int J Biochem Cell Biol"},{"key":"9212_CR3","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1152\/physrev.00007.2015","volume":"96","author":"DG Allen","year":"2016","unstructured":"Allen DG, Whitehead NP, Froehner SC. Absence of dystrophin disrupts skeletal muscle signaling: roles of Ca2+, reactive oxygen species, and nitric oxide in the development of muscular dystrophy. Physiol Rev. 2016;96:253\u2013305.","journal-title":"Physiol Rev"},{"key":"9212_CR4","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1007\/s00292-017-0265-1","volume":"38","author":"K Ohlendieck","year":"2017","unstructured":"Ohlendieck K, Swandulla D. Molecular pathogenesis of Duchenne muscular dystrophy-related fibrosis. Pathologe. 2017;38:21\u20139.","journal-title":"Pathologe"},{"key":"9212_CR5","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1007\/s11940-014-0287-4","volume":"16","author":"N Goemans","year":"2014","unstructured":"Goemans N, Buyse G. Current treatment and management of dystrophinopathies. Curr Treat Options Neurol. 2014;16:287.","journal-title":"Curr Treat Options Neurol"},{"key":"9212_CR6","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1016\/S1474-4422(18)30024-3","volume":"17","author":"DJ Birnkrant","year":"2018","unstructured":"Birnkrant DJ, Bushby K, Bann CM, Apkon SD, Blackwell A, Brumbaugh D, Case LE, Clemens PR, Hadjiyannakis S, Pandya S, Street N, Tomezsko J, Wagner KR, Ward LM, Weber DR, DMD Care Considerations Working Group. Diagnosis and management of Duchenne muscular dystrophy, part 1: diagnosis, and neuromuscular, rehabilitation, endocrine, and gastrointestinal and nutritional management. Lancet Neurol. 2018;17:251\u201367.","journal-title":"Lancet Neurol"},{"key":"9212_CR7","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1016\/S1474-4422(18)30025-5","volume":"17","author":"DJ Birnkrant","year":"2018","unstructured":"Birnkrant DJ, Bushby K, Bann CM, Alman BA, Apkon SD, Blackwell A, Case LE, Cripe L, Hadjiyannakis S, Olson AK, Sheehan DW, Bolen J, Weber DR, Ward LM, DMD Care Considerations Working Group. Diagnosis and management of Duchenne muscular dystrophy, part 2: respiratory, cardiac, bone health, and orthopaedic management. Lancet Neurol. 2018;17:347\u201361.","journal-title":"Lancet Neurol"},{"key":"9212_CR8","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1016\/S1474-4422(18)30026-7","volume":"17","author":"DJ Birnkrant","year":"2018","unstructured":"Birnkrant DJ, Bushby K, Bann CM, Apkon SD, Blackwell A, Colvin MK, Cripe L, Herron AR, Kennedy A, Kinnett K, Naprawa J, Noritz G, Poysky J, Street N, Trout CJ, Weber DR, Ward LM, DMD Care Considerations Working Group. Diagnosis and management of Duchenne muscular dystrophy, part 3: primary care, emergency management, psychosocial care, and transitions of care across the lifespan. Lancet Neurol. 2018;17:445\u201355.","journal-title":"Lancet Neurol"},{"key":"9212_CR9","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1016\/j.neubiorev.2013.03.016","volume":"37","author":"WM Snow","year":"2013","unstructured":"Snow WM, Anderson JE, Jakobson LS. Neuropsychological and neurobehavioral functioning in Duchenne muscular dystrophy: a review. Neurosci Biobehav Rev. 2013;37:743\u201352.","journal-title":"Neurosci Biobehav Rev"},{"key":"9212_CR10","first-page":"5","volume":"38","author":"T Moriuchi","year":"1991","unstructured":"Moriuchi T, Fujii Y, Kagawa N, Hizawa K. Autopsy study on the weight of the heart, liver, kidney and brain in Duchenne muscular dystrophy. Tokushima J Exp Med. 1991;38:5\u201313.","journal-title":"Tokushima J Exp Med"},{"key":"9212_CR11","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1097\/MPG.0b013e318217f5d9","volume":"53","author":"C Veropalumbo","year":"2011","unstructured":"Veropalumbo C, Del Giudice E, Capuano G, Gentile C, Di Cosmo N, Vajro P. Duchenne and Becker muscular dystrophy presenting as nonalcoholic fatty liver disease. J Pediatr Gastroenterol Nutr. 2011;53:463\u20134.","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"9212_CR12","first-page":"24","volume":"31","author":"L Politano","year":"2012","unstructured":"Politano L, Nigro G. Treatment of dystrophinopathic cardiomyopathy: review of the literature and personal results. Acta Myol. 2012;31:24\u201330.","journal-title":"Acta Myol"},{"key":"9212_CR13","doi-asserted-by":"crossref","first-page":"497","DOI":"10.5694\/j.1326-5377.1999.tb123758.x","volume":"171","author":"JL Hynson","year":"1999","unstructured":"Hynson JL, South M. Childhood hepatotoxicity with paracetamol doses less than 150\u00a0mg\/kg per day. Med J Aust. 1999;171:497.","journal-title":"Med J Aust"},{"key":"9212_CR14","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1111\/j.1365-2044.2007.05340.x","volume":"63","author":"B Pearce","year":"2008","unstructured":"Pearce B, Grant IS. Acute liver failure following therapeutic paracetamol administration in patients with muscular dystrophies. Anaesthesia. 2008;63:89\u201391.","journal-title":"Anaesthesia"},{"key":"9212_CR15","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1097\/MCO.0000000000000135","volume":"18","author":"LL Spriet","year":"2015","unstructured":"Spriet LL, Whitfield J. Taurine and skeletal muscle function. Curr Opin Clin Nutr Metab Care. 2015;18:96\u2013101.","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"9212_CR16","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/j.biocel.2015.07.016","volume":"66","author":"JR Terrill","year":"2015","unstructured":"Terrill JR, Grounds MD, Arthur PG. Taurine deficiency, synthesis and transport in the mdx mouse model for Duchenne muscular dystrophy. Int J Biochem Cell Biol. 2015;66:141\u20138.","journal-title":"Int J Biochem Cell Biol"},{"key":"9212_CR17","doi-asserted-by":"publisher","first-page":"3095","DOI":"10.1113\/JP271418","volume":"594","author":"JR Terrill","year":"2016","unstructured":"Terrill JR, Pinniger GJ, Graves JA, Grounds MD, Arthur PG. Increasing taurine intake and taurine synthesis improves skeletal muscle function in the mdx mouse model for Duchenne muscular dystrophy. J Physiol. 2016;594:3095\u2013110.","journal-title":"J Physiol"},{"key":"9212_CR18","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1186\/s12967-015-0610-1","volume":"13","author":"A Luca De","year":"2015","unstructured":"De Luca A, Pierno S, Camerino DC. Taurine: the appeal of a safe amino acid for skeletal muscle disorders. J Transl Med. 2015;13:243.","journal-title":"J Transl Med"},{"key":"9212_CR19","doi-asserted-by":"publisher","first-page":"e91514","DOI":"10.1371\/journal.pone.0091514","volume":"9","author":"DI Stapleton","year":"2014","unstructured":"Stapleton DI, Lau X, Flores M, Trieu J, Gehrig SM, Chee A, Naim T, Lynch GS, Koopman R. Dysfunctional muscle and liver glycogen metabolism in mdx dystrophic mice. PLoS ONE. 2014;9:e91514.","journal-title":"PLoS ONE"},{"key":"9212_CR20","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1210\/jcem-60-2-320","volume":"60","author":"GR Freidenberg","year":"1985","unstructured":"Freidenberg GR, Olefsky JM. Dissociation of insulin resistance and decreased insulin receptor binding in Duchenne muscular dystrophy. J Clin Endocrinol Metab. 1985;60:320\u20137.","journal-title":"J Clin Endocrinol Metab"},{"key":"9212_CR21","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.dsx.2017.08.006","volume":"12","author":"C Saure","year":"2018","unstructured":"Saure C, Caminiti C, Weglinski J, de Castro Perez F, Monges S. Energy expenditure, body composition, and prevalence of metabolic disorders in patients with Duchenne muscular dystrophy. Diabetes Metab Syndr. 2018;12:81\u20135.","journal-title":"Diabetes Metab Syndr"},{"key":"9212_CR22","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/j.csbj.2015.11.002","volume":"14","author":"S Murphy","year":"2015","unstructured":"Murphy S, Ohlendieck K. The biochemical and mass spectrometric profiling of the dystrophin complexome from skeletal muscle. Comput Struct Biotechnol J. 2015;14:20\u20137.","journal-title":"Comput Struct Biotechnol J"},{"key":"9212_CR23","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1002\/pmic.201500158","volume":"16","author":"A Holland","year":"2016","unstructured":"Holland A, Murphy S, Dowling P, Ohlendieck K. Pathoproteomic profiling of the skeletal muscle matrisome in dystrophinopathy associated myofibrosis. Proteomics. 2016;16:345\u201366.","journal-title":"Proteomics"},{"key":"9212_CR24","doi-asserted-by":"publisher","DOI":"10.1002\/prca.201700071","author":"SJ Carr","year":"2018","unstructured":"Carr SJ, Zahedi RP, Lochm\u00fcller H, Roos A. Mass spectrometry-based protein analysis to unravel the tissue pathophysiology in Duchenne muscular dystrophy. Proteom Clin Appl. 2018. https:\/\/doi.org\/10.1002\/prca.201700071 .","journal-title":"Proteom Clin Appl"},{"key":"9212_CR25","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1002\/mus.21873","volume":"43","author":"JH Shin","year":"2011","unstructured":"Shin JH, Hakim CH, Zhang K, Duan D. Genotyping mdx, mdx3cv, and mdx4cv mice by primer competition polymerase chain reaction. Muscle Nerve. 2011;43:283\u20136.","journal-title":"Muscle Nerve"},{"key":"9212_CR26","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1203\/00006450-199207000-00025","volume":"32","author":"I Danko","year":"1992","unstructured":"Danko I, Chapman V, Wolff JA. The frequency of revertants in mdx mouse genetic models for Duchenne muscular dystrophy. Pediatr Res. 1992;32:128\u201331.","journal-title":"Pediatr Res"},{"key":"9212_CR27","doi-asserted-by":"publisher","first-page":"4177","DOI":"10.1111\/febs.12267","volume":"280","author":"TA Partridge","year":"2013","unstructured":"Partridge TA. The mdx mouse model as a surrogate for Duchenne muscular dystrophy. FEBS J. 2013;280:4177\u201386.","journal-title":"FEBS J"},{"key":"9212_CR28","doi-asserted-by":"publisher","first-page":"2318","DOI":"10.1002\/pmic.201400471","volume":"15","author":"A Holland","year":"2015","unstructured":"Holland A, Dowling P, Meleady P, Henry M, Zweyer M, Mundegar RR, Swandulla D, Ohlendieck K. Label-free mass spectrometric analysis of the mdx-4cv diaphragm identifies the matricellular protein periostin as a potential factor involved in dystrophinopathy-related fibrosis. Proteomics. 2015;15:2318\u201331.","journal-title":"Proteomics"},{"key":"9212_CR29","doi-asserted-by":"publisher","first-page":"298","DOI":"10.3390\/proteomes3030298","volume":"3","author":"S Murphy","year":"2015","unstructured":"Murphy S, Zweyer M, Mundegar RR, Henry M, Meleady P, Swandulla D, Ohlendieck K. Concurrent label-free mass spectrometric analysis of dystrophin isoform Dp427 and the Myofibrosis marker collagen in crude extracts from mdx-4cv skeletal muscles. Proteomes. 2015;3:298\u2013327.","journal-title":"Proteomes"},{"key":"9212_CR30","first-page":"397","volume":"4","author":"S Murphy","year":"2015","unstructured":"Murphy S, Henry M, Meleady P, Zweyer M, Mundegar RR, Swandulla D, Ohlendieck K. Simultaneous pathoproteomic evaluation of the dystrophin-glycoprotein complex and secondary changes in the mdx-4cv mouse model of Duchenne muscular dystrophy. Biology (Basel). 2015;4:397\u2013423.","journal-title":"Biology (Basel)."},{"key":"9212_CR31","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2018.01.015","author":"S Murphy","year":"2018","unstructured":"Murphy S, Zweyer M, Henry M, Meleady P, Mundegar RR, Swandulla D, Ohlendieck K. Proteomic analysis of the sarcolemma-enriched fraction from dystrophic mdx-4cv skeletal muscle. J Proteom. 2018. https:\/\/doi.org\/10.1016\/j.jprot.2018.01.015 .","journal-title":"J Proteom"},{"key":"9212_CR32","doi-asserted-by":"publisher","first-page":"1357","DOI":"10.3892\/ijmm.2017.2952","volume":"39","author":"S Murphy","year":"2017","unstructured":"Murphy S, Dowling P, Zweyer M, Henry M, Meleady P, Mundegar RR, Swandulla D, Ohlendieck K. Proteomic profiling of mdx-4cv serum reveals highly elevated levels of the inflammation-induced plasma marker haptoglobin in muscular dystrophy. Int J Mol Med. 2017;39:1357\u201370.","journal-title":"Int J Mol Med"},{"key":"9212_CR33","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.jprot.2016.03.011","volume":"145","author":"S Murphy","year":"2016","unstructured":"Murphy S, Dowling P, Zweyer M, Mundegar RR, Henry M, Meleady P, Swandulla D, Ohlendieck K. Proteomic analysis of dystrophin deficiency and associated changes in the aged mdx-4cv heart model of dystrophinopathy-related cardiomyopathy. J Proteom. 2016;145:24\u201336.","journal-title":"J Proteom"},{"key":"9212_CR34","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1186\/s12014-015-9099-0","volume":"12","author":"S Murphy","year":"2015","unstructured":"Murphy S, Zweyer M, Henry M, Meleady P, Mundegar RR, Swandulla D, Ohlendieck K. Label-free mass spectrometric analysis reveals complex changes in the brain proteome from the mdx-4cv mouse model of Duchenne muscular dystrophy. Clin Proteom. 2015;12:27.","journal-title":"Clin Proteom"},{"key":"9212_CR35","doi-asserted-by":"publisher","first-page":"1292","DOI":"10.1073\/pnas.86.4.1292","volume":"86","author":"VM Chapman","year":"1989","unstructured":"Chapman VM, Miller DR, Armstrong D, Caskey CT. Recovery of induced mutations for X chromosome-linked muscular dystrophy in mice. Proc Natl Acad Sci USA. 1989;86:1292\u20136.","journal-title":"Proc Natl Acad Sci USA"},{"key":"9212_CR36","doi-asserted-by":"publisher","first-page":"11317","DOI":"10.3390\/molecules200611317","volume":"20","author":"A Holland","year":"2015","unstructured":"Holland A, Henry M, Meleady P, Winkler CK, Krautwald M, Brinkmeier H, Ohlendieck K. Comparative Label-free mass spectrometric analysis of mildly versus severely affected mdx mouse skeletal muscles identifies annexin, lamin, and vimentin as universal dystrophic markers. Molecules. 2015;20:11317\u201344.","journal-title":"Molecules"},{"key":"9212_CR37","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","volume":"72","author":"MM Bradford","year":"1976","unstructured":"Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248\u201354.","journal-title":"Anal Biochem"},{"key":"9212_CR38","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.ab.2017.11.022","volume":"543","author":"S Murphy","year":"2018","unstructured":"Murphy S, Ohlendieck K. Proteomic profiling of large myofibrillar proteins from dried and long-term stored polyacrylamide gels. Anal Biochem. 2018;543:8\u201311.","journal-title":"Anal Biochem"},{"key":"9212_CR39","doi-asserted-by":"publisher","first-page":"e0004837","DOI":"10.1371\/journal.pntd.0004837","volume":"10","author":"G Deslyper","year":"2016","unstructured":"Deslyper G, Colgan TJ, Cooper AJ, Holland CV, Carolan JC. A proteomic investigation of hepatic resistance to ascaris in a murine model. PLoS Negl Trop Dis. 2016;10:e0004837.","journal-title":"PLoS Negl Trop Dis"},{"key":"9212_CR40","doi-asserted-by":"publisher","first-page":"7369","DOI":"10.3748\/wjg.v23.i41.7369","volume":"23","author":"F O\u2019Sullivan","year":"2017","unstructured":"O\u2019Sullivan F, Keenan J, Aherne S, O\u2019Neill F, Clarke C, Henry M, Meleady P, Breen L, Barron N, Clynes M, Horgan K, Doolan P, Murphy R. Parallel mRNA, proteomics and miRNA expression analysis in cell line models of the intestine. World J Gastroenterol. 2017;23:7369\u201386.","journal-title":"World J Gastroenterol."},{"key":"9212_CR41","doi-asserted-by":"publisher","first-page":"D183","DOI":"10.1093\/nar\/gkw1138","volume":"45","author":"H Mi","year":"2017","unstructured":"Mi H, Huang X, Muruganujan A, Tang H, Mills C, Kang D, Thomas PD. PANTHER version 11: expanded annotation data from gene ontology and reactome pathways, and data analysis tool enhancements. Nucleic Acids Res. 2017;45:D183\u20139.","journal-title":"Nucleic Acids Res"},{"key":"9212_CR42","doi-asserted-by":"publisher","first-page":"D362","DOI":"10.1093\/nar\/gkw937","volume":"45","author":"D Szklarczyk","year":"2017","unstructured":"Szklarczyk D, Morris JH, Cook H, Kuhn M, Wyder S, Simonovic M, Santos A, Doncheva NT, Roth A, Bork P, Jensen LJ, von Mering C. The STRING database in 2017: quality-controlled protein-protein association networks, made broadly accessible. Nucleic Acids Res. 2017;45:D362\u20138.","journal-title":"Nucleic Acids Res"},{"key":"9212_CR43","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/B978-0-12-420119-4.00012-4","volume":"541","author":"JL Brunelle","year":"2014","unstructured":"Brunelle JL, Green R. One-dimensional SDS-polyacrylamide gel electrophoresis (1D SDS-PAGE). Methods Enzymol. 2014;541:151\u20139.","journal-title":"Methods Enzymol"},{"key":"9212_CR44","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1369\/jhc.2008.950105","volume":"56","author":"RR Mundegar","year":"2008","unstructured":"Mundegar RR, Franke E, Sch\u00e4fer R, Zweyer M, Wernig A. Reduction of high background staining by heating unfixed mouse skeletal muscle tissue sections allows for detection of thermostable antigens with murine monoclonal antibodies. J Histochem Cytochem. 2008;56:969\u201375.","journal-title":"J Histochem Cytochem"},{"key":"9212_CR45","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1186\/1479-7364-5-3-170","volume":"5","author":"RL Smathers","year":"2011","unstructured":"Smathers RL, Petersen DR. The human fatty acid-binding protein family: evolutionary divergences and functions. Hum Genom. 2011;5:170\u201391.","journal-title":"Hum Genom"},{"key":"9212_CR46","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1007\/s00281-009-0155-6","volume":"31","author":"H Ishibashi","year":"2009","unstructured":"Ishibashi H, Nakamura M, Komori A, Migita K, Shimoda S. Liver architecture, cell function, and disease. Semin Immunopathol. 2009;31:399\u2013409.","journal-title":"Semin Immunopathol"},{"key":"9212_CR47","doi-asserted-by":"publisher","first-page":"2901","DOI":"10.1096\/fj.14-250555","volume":"28","author":"C Kampf","year":"2014","unstructured":"Kampf C, Mardinoglu A, Fagerberg L, Hallstr\u00f6m BM, Edlund K, Lundberg E, Pont\u00e9n F, Nielsen J, Uhlen M. The human liver-specific proteome defined by transcriptomics and antibody-based profiling. FASEB J. 2014;28:2901\u201314.","journal-title":"FASEB J"},{"key":"9212_CR48","doi-asserted-by":"publisher","first-page":"1260419","DOI":"10.1126\/science.1260419","volume":"347","author":"M Uhl\u00e9n","year":"2015","unstructured":"Uhl\u00e9n M, Fagerberg L, Hallstr\u00f6m BM, Lindskog C, Oksvold P, Mardinoglu A, Sivertsson \u00c5, Kampf C, Sj\u00f6stedt E, Asplund A, Olsson I, Edlund K, Lundberg E, Navani S, Szigyarto CA, Odeberg J, Djureinovic D, Takanen JO, Hober S, Alm T, Edqvist PH, Berling H, Tegel H, Mulder J, Rockberg J, Nilsson P, Schwenk JM, Hamsten M, von Feilitzen K, Forsberg M, Persson L, Johansson F, Zwahlen M, von Heijne G, Nielsen J, Pont\u00e9n F. Proteomics. Tissue-based map of the human proteome. Science. 2015;347:1260419.","journal-title":"Science"},{"key":"9212_CR49","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1038\/nature13302","volume":"509","author":"MS Kim","year":"2014","unstructured":"Kim MS, Pinto SM, Getnet D, Nirujogi RS, Manda SS, Chaerkady R, Madugundu AK, Kelkar DS, Isserlin R, Jain S, Thomas JK, Muthusamy B, Leal-Rojas P, Kumar P, Sahasrabuddhe NA, Balakrishnan L, Advani J, George B, Renuse S, Selvan LD, Patil AH, Nanjappa V, Radhakrishnan A, Prasad S, Subbannayya T, Raju R, Kumar M, Sreenivasamurthy SK, Marimuthu A, Sathe GJ, Chavan S, Datta KK, Subbannayya Y, Sahu A, Yelamanchi SD, Jayaram S, Rajagopalan P, Sharma J, Murthy KR, Syed N, Goel R, Khan AA, Ahmad S, Dey G, Mudgal K, Chatterjee A, Huang TC, Zhong J, Wu X, Shaw PG, Freed D, Zahari MS, Mukherjee KK, Shankar S, Mahadevan A, Lam H, Mitchell CJ, Shankar SK, Satishchandra P, Schroeder JT, Sirdeshmukh R, Maitra A, Leach SD, Drake CG, Halushka MK, Prasad TS, Hruban RH, Kerr CL, Bader GD, Iacobuzio-Donahue CA, Gowda H, Pandey A. A draft map of the human proteome. Nature. 2014;509:575\u201381.","journal-title":"Nature"},{"key":"9212_CR50","doi-asserted-by":"publisher","first-page":"582","DOI":"10.1038\/nature13319","volume":"509","author":"M Wilhelm","year":"2014","unstructured":"Wilhelm M, Schlegl J, Hahne H, Gholami AM, Lieberenz M, Savitski MM, Ziegler E, Butzmann L, Gessulat S, Marx H, Mathieson T, Lemeer S, Schnatbaum K, Reimer U, Wenschuh H, Mollenhauer M, Slotta-Huspenina J, Boese JH, Bantscheff M, Gerstmair A, Faerber F, Kuster B. Mass-spectrometry-based draft of the human proteome. Nature. 2014;509:582\u20137.","journal-title":"Nature"},{"key":"9212_CR51","doi-asserted-by":"publisher","first-page":"712","DOI":"10.1016\/j.jhep.2014.10.036","volume":"62","author":"A Teufel","year":"2015","unstructured":"Teufel A. Bioinformatics and database resources in hepatology. J Hepatol. 2015;62:712\u20139.","journal-title":"J Hepatol"},{"issue":"8","key":"9212_CR52","doi-asserted-by":"publisher","first-page":"1239","DOI":"10.1111\/liv.12173","volume":"33","author":"Y Zhang","year":"2013","unstructured":"Zhang Y, Yang C, Wang S, Chen T, Li M, Wang X, Li D, Wang K, Ma J, Wu S, Zhang X, Zhu Y, Wu J, He F. LiverAtlas: a unique integrated knowledge database for systems-level research of liver and hepatic disease. Liver Int. 2013;33(8):1239\u201348.","journal-title":"Liver Int"},{"key":"9212_CR53","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1186\/1477-5956-7-35","volume":"7","author":"G Gazzana","year":"2009","unstructured":"Gazzana G, Borlak J. An update on the mouse liver proteome. Proteome Sci. 2009;7:35.","journal-title":"Proteome Sci."},{"key":"9212_CR54","doi-asserted-by":"publisher","first-page":"1076","DOI":"10.1016\/j.cmet.2014.11.002","volume":"20","author":"SB Azimifar","year":"2014","unstructured":"Azimifar SB, Nagaraj N, Cox J, Mann M. Cell-type-resolved quantitative proteomics of murine liver. Cell Metab. 2014;20:1076\u201387.","journal-title":"Cell Metab"},{"key":"9212_CR55","doi-asserted-by":"publisher","first-page":"3190","DOI":"10.1074\/mcp.M116.060145","volume":"15","author":"C Ding","year":"2016","unstructured":"Ding C, Li Y, Guo F, Jiang Y, Ying W, Li D, Yang D, Xia X, Liu W, Zhao Y, He Y, Li X, Sun W, Liu Q, Song L, Zhen B, Zhang P, Qian X, Qin J, He F. A cell-type-resolved liver proteome. Mol Cell Proteom. 2016;15:3190\u2013202.","journal-title":"Mol Cell Proteom"},{"key":"9212_CR56","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1097\/MCO.0000000000000031","volume":"17","author":"AE Thumser","year":"2014","unstructured":"Thumser AE, Moore JB, Plant NJ. Fatty acid binding proteins: tissue-specific functions in health and disease. Curr Opin Clin Nutr Metab Care. 2014;17:124\u20139.","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"9212_CR57","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1016\/j.bbrc.2017.09.046","volume":"493","author":"J Jung","year":"2017","unstructured":"Jung J, Wang J, Groenendyk J, Lee D, Michalak M, Agellon LB. Fatty acid binding protein (Fabp) 5 interacts with the calnexin cytoplasmic domain at the endoplasmic reticulum. Biochem Biophys Res Commun. 2017;493:202\u20136.","journal-title":"Biochem Biophys Res Commun"},{"key":"9212_CR58","doi-asserted-by":"publisher","first-page":"7153","DOI":"10.1073\/pnas.1507719112","volume":"112","author":"Y Hathout","year":"2015","unstructured":"Hathout Y, Brody E, Clemens PR, Cripe L, DeLisle RK, Furlong P, Gordish-Dressman H, Hache L, Henricson E, Hoffman EP, Kobayashi YM, Lorts A, Mah JK, McDonald C, Mehler B, Nelson S, Nikrad M, Singer B, Steele F, Sterling D, Sweeney HL, Williams S, Gold L. Large-scale serum protein biomarker discovery in Duchenne muscular dystrophy. Proc Natl Acad Sci USA. 2015;112:7153\u20138.","journal-title":"Proc Natl Acad Sci USA"},{"key":"9212_CR59","doi-asserted-by":"publisher","first-page":"241","DOI":"10.3233\/JND-140066","volume":"2","author":"PM Burch","year":"2015","unstructured":"Burch PM, Pogoryelova O, Goldstein R, Bennett D, Guglieri M, Straub V, Bushby K, Lochm\u00fcller H, Morris C. Muscle-derived proteins as serum biomarkers for monitoring disease progression in three forms of muscular dystrophy. J Neuromuscul Dis. 2015;2:241\u201355.","journal-title":"J Neuromuscul Dis"},{"key":"9212_CR60","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/s12014-016-9109-x","volume":"13","author":"Y Hathout","year":"2016","unstructured":"Hathout Y, Seol H, Han MH, Zhang A, Brown KJ, Hoffman EP. Clinical utility of serum biomarkers in Duchenne muscular dystrophy. Clin Proteom. 2016;13:9.","journal-title":"Clin Proteom"},{"key":"9212_CR61","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1186\/s12872-015-0026-0","volume":"15","author":"U Hoffmann","year":"2015","unstructured":"Hoffmann U, Espeter F, Wei\u00df C, Ahmad-Nejad P, Lang S, Brueckmann M, Akin I, Neumaier M, Borggrefe M, Behnes M. Ischemic biomarker heart-type fatty acid binding protein (hFABP) in acute heart failure\u2014diagnostic and prognostic insights compared to NT-proBNP and troponin I. BMC Cardiovasc Disord. 2015;15:50.","journal-title":"BMC Cardiovasc Disord"},{"key":"9212_CR62","doi-asserted-by":"publisher","first-page":"3606","DOI":"10.1038\/s41598-018-22082-6","volume":"8","author":"Y Urasaki","year":"2018","unstructured":"Urasaki Y, Zhang C, Cheng JX, Le TT. Quantitative assessment of liver steatosis and affected pathways with molecular imaging and proteomic profiling. Sci Rep. 2018;8:3606.","journal-title":"Sci Rep"},{"key":"9212_CR63","doi-asserted-by":"publisher","first-page":"1049","DOI":"10.1002\/cam4.1020","volume":"6","author":"T Ohata","year":"2017","unstructured":"Ohata T, Yokoo H, Kamiyama T, Fukai M, Aiyama T, Hatanaka Y, Hatanaka K, Wakayama K, Orimo T, Kakisaka T, Kobayashi N, Matsuno Y, Taketomi A. Fatty acid-binding protein 5 function in hepatocellular carcinoma through induction of epithelial-mesenchymal transition. Cancer Med. 2017;6:1049\u201361.","journal-title":"Cancer Med"},{"key":"9212_CR64","doi-asserted-by":"publisher","first-page":"14873","DOI":"10.1007\/s13277-016-5350-1","volume":"37","author":"W Wang","year":"2016","unstructured":"Wang W, Chu HJ, Liang YC, Huang JM, Shang CL, Tan H, Liu D, Zhao YH, Liu TY, Yao SZ. FABP5 correlates with poor prognosis and promotes tumor cell growth and metastasis in cervical cancer. Tumour Biol. 2016;37:14873\u201383.","journal-title":"Tumour Biol"},{"issue":"Suppl","key":"9212_CR65","doi-asserted-by":"publisher","first-page":"S138","DOI":"10.1194\/jlr.R800079-JLR200","volume":"50","author":"SJ Wakil","year":"2009","unstructured":"Wakil SJ, Abu-Elheiga LA. Fatty acid metabolism: target for metabolic syndrome. J Lipid Res. 2009;50(Suppl):S138\u201343.","journal-title":"J Lipid Res"},{"key":"9212_CR66","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/j.2040-4603.2018.tb00008.x","volume":"8","author":"M Alves-Bezerra","year":"2017","unstructured":"Alves-Bezerra M, Cohen DE. Triglyceride Metabolism in the Liver. Compr Physiol. 2017;8:1\u20138.","journal-title":"Compr Physiol."},{"key":"9212_CR67","doi-asserted-by":"publisher","first-page":"942","DOI":"10.1210\/en.2007-1713","volume":"149","author":"NA Ducharme","year":"2008","unstructured":"Ducharme NA, Bickel PE. Lipid droplets in lipogenesis and lipolysis. Endocrinology. 2008;149:942\u20139.","journal-title":"Endocrinology"},{"key":"9212_CR68","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1016\/j.biochi.2013.08.026","volume":"96","author":"C Sztalryd","year":"2014","unstructured":"Sztalryd C, Kimmel AR. Perilipins: lipid droplet coat proteins adapted for tissue-specific energy storage and utilization, and lipid cytoprotection. Biochimie. 2014;96:96\u2013101.","journal-title":"Biochimie"},{"key":"9212_CR69","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1042\/BSR20080015","volume":"28","author":"K Hagopian","year":"2008","unstructured":"Hagopian K, Ramsey JJ, Weindruch R. Enzymes of glycerol and glyceraldehyde metabolism in mouse liver: effects of caloric restriction and age on activities. Biosci Rep. 2008;28:107\u201315.","journal-title":"Biosci Rep"},{"key":"9212_CR70","doi-asserted-by":"publisher","first-page":"2089","DOI":"10.1016\/j.bbapap.2010.08.001","volume":"1804","author":"K Ohlendieck","year":"2010","unstructured":"Ohlendieck K. Proteomics of skeletal muscle glycolysis. Biochim Biophys Acta. 2010;1804:2089\u2013101.","journal-title":"Biochim Biophys Acta"},{"key":"9212_CR71","doi-asserted-by":"publisher","first-page":"4610","DOI":"10.1002\/pmic.200600082","volume":"6","author":"P Doran","year":"2006","unstructured":"Doran P, Martin G, Dowling P, Jockusch H, Ohlendieck K. Proteome analysis of the dystrophin-deficient MDX diaphragm reveals a drastic increase in the heat shock protein cvHSP. Proteomics. 2006;6:4610\u201321.","journal-title":"Proteomics"},{"key":"9212_CR72","doi-asserted-by":"publisher","first-page":"2312","DOI":"10.1002\/pmic.201200578","volume":"13","author":"A Holland","year":"2013","unstructured":"Holland A, Dowling P, Zweyer M, Swandulla D, Henry M, Clynes M, Ohlendieck K. Proteomic profiling of cardiomyopathic tissue from the aged mdx model of Duchenne muscular dystrophy reveals a drastic decrease in laminin, nidogen and annexin. Proteomics. 2013;13:2312\u201323.","journal-title":"Proteomics"},{"key":"9212_CR73","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1016\/j.tibs.2005.01.005","volume":"30","author":"JW Kim","year":"2005","unstructured":"Kim JW, Dang CV. Multifaceted roles of glycolytic enzymes. Trends Biochem Sci. 2005;30:142\u201350.","journal-title":"Trends Biochem Sci"},{"key":"9212_CR74","doi-asserted-by":"publisher","first-page":"2629","DOI":"10.1038\/onc.2016.410","volume":"36","author":"X Yu","year":"2017","unstructured":"Yu X, Li S. Non-metabolic functions of glycolytic enzymes in tumorigenesis. Oncogene. 2017;36:2629\u201336.","journal-title":"Oncogene"},{"key":"9212_CR75","doi-asserted-by":"publisher","first-page":"e0151547","DOI":"10.1371\/journal.pone.0151547","volume":"11","author":"M Mazzorana","year":"2016","unstructured":"Mazzorana M, Hussain R, Sorensen T. Ca-dependent folding of human calumenin. PLoS ONE. 2016;11:e0151547.","journal-title":"PLoS ONE"},{"key":"9212_CR76","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1042\/BJ20101825","volume":"434","author":"J Wang","year":"2011","unstructured":"Wang J, Pantopoulos K. Regulation of cellular iron metabolism. Biochem J. 2011;434:365\u201381.","journal-title":"Biochem J"},{"key":"9212_CR77","doi-asserted-by":"publisher","first-page":"706","DOI":"10.1016\/j.bbagen.2010.03.019","volume":"1800","author":"RR Crichton","year":"2010","unstructured":"Crichton RR, Declercq JP. X-ray structures of ferritins and related proteins. Biochim Biophys Acta. 2010;1800:706\u201318.","journal-title":"Biochim Biophys Acta"},{"key":"9212_CR78","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/0005-2728(96)00022-9","volume":"1275","author":"PM Harrison","year":"1996","unstructured":"Harrison PM, Arosio P. The ferritins: molecular properties, iron storage function and cellular regulation. Biochim Biophys Acta. 1996;1275:161\u2013203.","journal-title":"Biochim Biophys Acta"},{"key":"9212_CR79","doi-asserted-by":"publisher","first-page":"229","DOI":"10.3892\/ijmm.2012.1006","volume":"30","author":"S Carberry","year":"2012","unstructured":"Carberry S, Zweyer M, Swandulla D, Ohlendieck K. Proteomics reveals drastic increase of extracellular matrix proteins collagen and dermatopontin in the aged mdx diaphragm model of Duchenne muscular dystrophy. Int J Mol Med. 2012;30:229\u201334.","journal-title":"Int J Mol Med"},{"key":"9212_CR80","doi-asserted-by":"publisher","first-page":"544","DOI":"10.3892\/ijmm.2013.1429","volume":"32","author":"S Carberry","year":"2013","unstructured":"Carberry S, Brinkmeier H, Zhang Y, Winkler CK, Ohlendieck K. Comparative proteomic profiling of soleus, extensor digitorum longus, flexor digitorum brevis and interosseus muscles from the mdx mouse model of Duchenne muscular dystrophy. Int J Mol Med. 2013;32:544\u201356.","journal-title":"Int J Mol Med"},{"key":"9212_CR81","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1016\/j.nmd.2018.03.008","volume":"28","author":"J Rouillon","year":"2018","unstructured":"Rouillon J, Lefebvre T, Denard J, Puy V, Daher R, Ausseil J, Zocevic A, Fogel P, Peoc\u2019h K, Wong B, Servais L, Voit T, Puy H, Karim Z, Svinartchouk F. High urinary ferritin reflects myoglobin iron evacuation in DMD patients. Neuromuscul Disord. 2018;28:564\u201371.","journal-title":"Neuromuscul Disord"}],"container-title":["Clinical Proteomics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12014-018-9212-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12014-018-9212-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12014-018-9212-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T22:10:37Z","timestamp":1775254237000},"score":1,"resource":{"primary":{"URL":"https:\/\/clinicalproteomicsjournal.biomedcentral.com\/articles\/10.1186\/s12014-018-9212-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,29]]},"references-count":81,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["9212"],"URL":"https:\/\/doi.org\/10.1186\/s12014-018-9212-2","relation":{},"ISSN":["1542-6416","1559-0275"],"issn-type":[{"value":"1542-6416","type":"print"},{"value":"1559-0275","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,29]]},"assertion":[{"value":"14 August 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 October 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 October 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"34"}}